• Korean Journal of Veterinary Research
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• v.42 no.2
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• pp.269-275
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• 2002

The aim of this study was to investigate the usefulness and effectiveness of thermography in horse. Total 21 horses associated with locomotors, wound, and ophthalmic disease were investigated. Thermographically, the wannest area in normal limb was coronary band ($27.26^{\circ}C$), and carpus, metacarpus, fetlock, and pastern area were $26.64^{\circ}C$, $24.42^{\circ}C$, $23.64^{\circ}C$ and $23.06^{\circ}C$, respectively. The temperature($^{\circ}C$) of horses with lameness, swelling, nervous, ataxia was lower(cold spot) than surrounding tissue or symmetry area, and with heat, signs of inflammation was increased(hot spot). These results suggest that the thermography is useful for the early detection of locomotors, wound, and ophthalmic disease in horse and an excellent adjunct to clinical examination.

• Journal of the Korean association of regional geographers
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• v.21 no.3
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• pp.583-592
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• 2015

As the increase of an environmental disease has become a social problem after industrialization, academic interest in a spatial difference and characteristics of an environmental disease is on rise. The purpose of this study is to analyze the spatial distribution and characteristics of an environmental disease using the data provided by National Health Insurance Corporation in 2009. This research is focusing on atopic dermatitis among a variety of environmental diseases and shows the map that atopic dermatitis patients are distributed. Also, The Local Moran's I show how spatial autocorrelation of atopic dermatitis patients are distributed. First, the distribution of atopic dermatitis patients show the spatial difference. Second, 42 places including the western part of Incheon are hot spots of atopic dermatitis. Third, 39 places including Danyang are cold spot of atopic dermatitis. Forth, Jeju-si and Seogwipo-si are unusually hot spot of atopic dermatitis. These results have important implications that further research need to be done in public health geography.

• The Plant Pathology Journal
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• v.30 no.2
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• pp.125-135
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• 2014

A population model of bacterial spot caused by Xanthomonas campestris pv. vesicatoria on hot pepper was developed to predict the primary disease infection date. The model estimated the pathogen population on the surface and within the leaf of the host based on the wetness period and temperature. For successful infection, at least 5,000 cells/ml of the bacterial population were required. Also, wind and rain were necessary according to regression analyses of the monitored data. Bacterial spot on the model is initiated when the pathogen population exceeds $10^{15}cells/g$ within the leaf. The developed model was validated using 94 assessed samples from 2000 to 2007 obtained from monitored fields. Based on the validation study, the predicted initial infection dates varied based on the year rather than the location. Differences in initial infection dates between the model predictions and the monitored data in the field were minimal. For example, predicted infection dates for 7 locations were within the same month as the actual infection dates, 11 locations were within 1 month of the actual infection, and only 3 locations were more than 2 months apart from the actual infection. The predicted infection dates were mapped from 2009 to 2012; 2011 was the most severe year. Although the model was not sensitive enough to predict disease severity of less than 0.1% in the field, our model predicted bacterial spot severity of 1% or more. Therefore, this model can be applied in the field to determine when bacterial spot control is required.

• Journal of Genetic Medicine
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• v.13 no.1
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• pp.20-25
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• 2016

Purpose: Xeroderma pigmentosum (XP) is rare autosomal recessive genetic disorder of DNA repair in which the ability to repair damage caused by ultraviolet light is deficient. We reported the first molecularly confirmed Korean patient of XP by targeted exome sequencing. The prevalence of XP included all subtype and carrier frequency of XP-A the using public data were estimated for the first time in South Korea. Materials and Methods: We described a 4-year-old Korean girl with clinical diagnosis of XP. We performed targeted exome sequencing in the patient for genetic confirmation considering disease genetic heterogeneity and for differential diagnosis. We verified a carrier frequency of c.390-1G>C in XPA gene known as mutational hot spot using Korean Reference Genome Data Base. We estimated the period prevalence of all subtypes of XP based on claims data of the Health Insurance Review and Assessment Service in South Korea. Results: We identified homozygous splicing mutation of XPA (c.390-1G>C) in the patient. The carrier frequency of risk for XPA (c.390-1G>C) was relatively high 1.608 e-03 (allele count 2/1244). The prevalence of XP in South Korea was 0.3 per million people. Conclusion: We expect that c.390-1G>C is hot spot for the mutation of XPA and possible founder variant in South Korea. However, the prevalence in South Korea was extremely low compared with Western countries and Japan.

• The Plant Pathology Journal
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• v.27 no.2
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• pp.183-186
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• 2011

During the summer of 2005, specimens of soybean cultivars (Daepung, Daewon, Hwanggeum and Taegwang) showing frogeye leaf spot (FLS) were obtained from various areas in Korea. Eight isolates identified as Cercospora sojina were inoculated on the adaxial leaf surfaces of 63 Korean soybean cultivars; the disease responses to each isolate were evaluated 14 days and 21 days after inoculation. Based on the disease responses (resistant or susceptible) of the cultivars by the isolates, a set of cultivars (Anpeong, Bogwang, Cheongdu No. 1, Cheongja No. 3, Dachae, Daemang, Jangwon, Namhae, Sowon, Taegwang) were selected and inoculated with seven isolates for further testing pathogenic variance. Interestingly, 6 out of 7 tested C. sojina isolates revealed differential ability in infecting different soybean cultivars. This result may indicate the possibility of new race occurrence or pathogenic variation; this also presents evidence for prevalent FLS occurrence during humid and hot weather in Korea.

• Journal of Animal Science and Technology
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• v.57 no.11
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• pp.32.1-32.8
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• 2015

Peste des petits ruminants (PPR) is considered to be one of the main constraints to enhancing the productivity of goats and sheep in regions where it is present and becoming endemic. PPR was recognized in Pakistan in early 1990s but got importance during the Participatory Disease Surveillance (PDS) of Rinderpest Eradication Campaign. Lot of research work has been initiated during last decade towards disease epidemiology, risk factor recognition, laboratory diagnosis, vaccination and demonstration of control strategies. Although there are ongoing projects working towards the progressive control of the disease in country yet there is need to have a national level control program for PPR. Also there is need to have comprehensive social economic surveys, disease hot spot recognition and identification of role of other species in disease transmission. With combined efforts of local and national authorities and political will, there is high likelihood that this devastating disease can be controlled and eventually eradicated in near future.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.39 no.1
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• pp.29-40
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• 2021

Risk factors that threaten public safety such as crime, fire, and traffic accidents have spatial characteristics. Since each region has different dangerous environments, it is necessary to analyze the spatial pattern of risk factors for each sector such as traffic accident, fire, crime, and living safety. The purpose of this study is to analyze the spatial distribution pattern of local safety level index, which act as an index that rates the safety level of each sector (traffic accident, fire, crime, living safety, suicide, and infectious disease) for basic local governments across the nation. The following analysis tools were used to analyze the spatial autocorrelation of local safety level index : Global Moran's I, Local Moran's I, and Getis-Ord's G⁎i. The result of the analysis shows that the distribution of safety level on traffic accidents, fire, and suicide tends to be more clustered spatially compared to the safety level on crime, living safety, and infectious disease. As a result of analyzing significant spatial correlations between different regions, it was found that the Seoul metropolitan areas are relatively safe compared to other cities based on the integrated index of local safety. In addition, hot spot analysis using statistical values from Getis-Ord's G⁎i derived three hot spots(Samchuck, Cheongsong-gun, and Gimje) in which safety-vulnerable areas are clustered and 15 cold spots which are clusters of areas with high safety levels. These research findings can be used as basic data when the government is making policies to improve the safety level by identifying the spatial distribution and the spatial pattern in areas with vulnerable safety levels.

• Imaging Science in Dentistry
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• v.36 no.3
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• pp.157-162
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• 2006

Familial gigantiform cementoma is a rare fibre-cemento-osseous disease of the jaws which appears to be transmitted as an autosomal dominant trait with variable expressivity of the phenotype. A 7-year-old girl visited DKUDH complaining of the painless facial deformity. Clinically, significant facio-lingual expansion was observed at the left maxilla, left mandibular body and symphysis portion. Malposition of lower anterior teeth was found. Panoramic radiograph and CT scan showed the extensive expansile mixed lesion at maxilla and mandible. Bone scan revealed hot spot at the maxilla and left side of mandible. Histologic examination revealed moderately dense fibrous connective tissue with scattered masses resembling cementum. The patient's mother had a history of the mandibular resection due to benign tumor. Her younger brother had buccal expansion of right mandible. We report our finding of a family that has exhibited clinical, radiographic and histologic findings consistent with the familial gigantiform cementoma.

• The Plant Pathology Journal
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• v.34 no.2
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• pp.93-103
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• 2018

Leaf blotch of wheat caused by Bipolaris sorokiniana is a major constraint to wheat production, causing significant yield reduction resulting in severe economic impact. The present study characterizes to determine and compare pathogenic variability exist/not based on components of leaf blotch disease development and level of aggressiveness due to agroclimatic condition of B. sorokiniana in wheat. A total of 169 virulent isolates of B. sorokiniana isolated from spot blotch infected leaf from different wheat growing agroclimate of Bangladesh. Pathogenic variability was investigated on a susceptible wheat variety 'kanchan' now in Bangladesh. A clear evidence of positive relationship among the components was recorded. From hierarchical cluster analysis five groups were originating among the isolates. It resolved that a large amount of pathogenic diversity exists in Bipolaris sorokiniana. Variation in aggressiveness was found among the isolates from different wheat growing areas. Most virulent isolates BS 24 and BS 33 belonging to High Ganges River Flood Plain agro-climatic zones considered by rice-wheat cropping pattern, hot and humid weather, high land and low organic matter content in soil. Positive relationship was found between pathogenic variability and aggressiveness with agro-climatic condition.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.sup3
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• pp.59-64
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• 2016

Breast cancer (BC) is the most common cancer in females (27% of the total) and the main cause of death (16%) due to cancer in women in developed and developing countries. Variations in its incidence rate among geographical areas are due to various contributing factors. Since there have been a lack of studies on this topic in our country, the present spatial analysis of breast cancer incidence in Iran in 2009 was conducted using data from the national cancer registry system. The reported incidences of the disease were standardized according to the World Health Organization population and the direct method. Then data was inserted into the GIS software and finally, using the Hot Spot Analysis (Geties-Ord Gi), high-risk areas were drawn. Provinces with incidences 1.96 SD higher or lower than the national average were considered as hot spots or cold spots, at the significance level of 0.05%. In 2009, a total of 7,582 cases of BC occurred in Iran. The annual incidence was 33.2 per hundred thousand people. Our study showed that the highest incidence of BC in women occurred in the central provinces of the country, Tehran, Isfahan, Yazd, Markazi and Fars. The results of hot spots analysis showed that the distribution of high-risk BC was focused in central parts of Iran, especially Isfahan province (p <0.01). The other provinces were not significantly different from the national average. The higher incidence in central provinces may be due to greater exposure to carcinogens in urban areas, a Western lifestyle and high prevalence of other risk factors. Further epidemiological studies about the etiology and early detection of BC are essential.