• Journal of applied mathematics & informatics
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• 제27권3_4호
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• pp.779-793
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• 2009

This paper deals with a delayed SEIRS epidemic model with pulse vaccination and crowded incidence rate. Moreover, the case of vertical and horizontal transmission is considered. By using the discrete dynamical system determined by the stroboscopic map, the exact infection-free periodic solution of the SEIRS model is obtained. Further, by employing the comparison arguments, we prove that under the condition that $R_*$ < 1 the infection-free periodic solution is globally attractive, and that under the condition that $R^*$ > 1 the disease is uniformly persistent, which means that after some period of time the disease will become endemic.

• 한국동물위생학회지
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• 제13권1호
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• pp.90-95
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• 1990

1) During 5 month(Oct. 1988-Feb. 1989), abortion(11 heads), stillbirth(3 heads), and congenital abnormalities(28 heads) of newborn were occurred in 42 milk cows raised in Cheju island. These cows were diagnosed with Akabane disease by clinical, pathological and serological test. 2) In May and Oct. 1989, 213 tattles at 10 farms were investigated on the actual condition of possessing Akabane antibody. The results was that 210 heads(98.6%) in 213 cattles reacted as positive condition in Akabane antibody. The antibody titer was from 4 to over 256. 3) During some years, the author suppose that the vaccination for Akabane disease will be unnecessary because of higher positive antibody reaction except the newly introduced cattle.

• Safety and Health at Work
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• 제3권1호
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• pp.11-16
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• 2012

Lead poisoning is one of the earliest identified and most known occupational disease. Its acute effects have been recognized from antiquity when this condition principally afflicted manual workers and slaves, actually scarcely considered by the medicine of that time. The Industrial Revolution caused an epidemic of metal intoxication, urging scientists and physician of that period to study and identify specific symptoms and organ alterations related to chronic lead poisoning. During the 20th century, the acknowledgment of occupational and environmental toxicity of lead fostered public awareness and legislation to protect health. More recently, the identification of sub-clinical effects have greatly modified the concept of lead poisoning and the approaches of medicine towards this condition. Nowadays, lead poisoning is rarely seen in developed countries, but it still represents a major environmental problem in certain areas. Consequently, it may appear as a paradigm of "occupational and environmental disease," and the history of this condition seems to parallel the historical development of modern "Occupational and Environmental Health" as a more complete medical discipline.

• Molecular & Cellular Toxicology
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• 제5권2호
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• pp.108-112
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• 2009

Alzheimer's disease(AD) is a neurodegenerative disorder characterized pathologically by senile plaques, neurofibrillary tangles, and synapse loss. Especially, extracellular beta-amyloid (Abeta) deposition is a major pathological hallmark of Alzheimer's disease (AD). In AD senile plaques, high level of iron and car-bonylated Abeta were detected. Iron has a Lewis acid property which can increase the electrophilicity of carbonyls, which may react catalytically with nucleophiles, such as amines. Hence, this study investigated whether or not iron could promote the carbonylation of amine with malondialdehyde (MDA) in the physiological condition. As the basic study, we examined that iron might promote the conjugation reaction between propylamine, monoamine molecule and MDA in the physiological condition. As the concentration of iron increased, the fluorescence intensity produced from the conjugation reaction increased in a dose-dependent manner. Instead of propylamine, we applied the same reaction condition to Abeta 1-40 peptide, one of major components founded in AD senile plaques for the conjugation reaction. As the result, the fluorescence intensity produced from the conjugation reaction between Abeta 1-40 peptide and MDA showed the similar trend to that of the reaction used with propylamine. This study suggests that iron can accelerate the conjugation reaction of MDA to Abeta 1-40 peptide and play an another important role in deterioration of AD brain.

• 척추신경추나의학회지
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• 제5권1호
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• pp.57-66
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• 2010

항통을 주소로 내원한 환자의 크론병에 대한 침구(鍼灸)치료로 복통 및 설사의 관해 상태가 되는 양호한 효과를 얻었기에 보고하는 바이다. 다만, 치료 기간이 짧아 증상의 변화의 추적이 필요한 상태이며, 다양한 임상적 연구를 위한 임상사례 데이터가 축적되어야 할 것으로 사료된다.

• 대한예방한의학회지
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• 제19권2호
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• pp.51-56
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• 2015

Objective : We analyzed present condition of cooperative medical care using claims data of HEALTH INSURANCE REVIEW & ASSESSMENT SERVICE form patients treated by Korean-Western cooperative medicine. The study aimed to offer guidelines in selecting disease-related research in developing Korean-Western convergence technology. Method : Based on the patients using Korean medical service, we analyzed claims data of patients using Korean medical service and western medical service from January 2012 to December 2013. We were assigned to the server remotely. With the concept of 'episode of care', we rebuilt claims data and analyzed present condition of cooperative medical usage. Results : We analyzed present condition of cooperative medical care per episode of care. Among outpatients, Low back pain, lumbar region(M5456) was the highest number. Among inpatients, Sciatica due to intervertebral disc disorder(M511) was the highest number. Conclusion : Based on the claims data provided by HEALTH INSURANCE REVIEW & ASSESSMENT SERVICE, we have derived a list of multy frequently disease frequently treated by cooperative medical care by analyzing present condition.

• 근관절건강학회지
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• 제27권3호
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• pp.289-297
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• 2020

Purpose: This descriptive study aimed to identify the foot health condition and related characteristics of nurses. Methods: A literature-based questionnaire was developed and distributed to 472 nurses in a university hospital in B city, and data were collected from August 1 to August 15, 2020. The Foot Health Status Questionnaire (FHSQ) was used to measure foot health condition. Results: The most common foot diseases among the participants were plantar fasciitis (7.8%) and hallux valgus (7.0%). To relieve foot pain, most nurses used relaxation techniques, stretching, elevating the legs, and foot massage. The level of foot health condition among nurses was lower than that of older persons or the general public with chronic foot disease. The foot health condition of the nurses showed that the lower the age and the greater the number of foot diseases, the more severe the pain and dysfunction. Conclusion: The study shows that there is a need for interventions that will raise nurses' awareness about foot health and induce better foot health management.

• 한국치위생학회지
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• 제9권3호
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• pp.248-261
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• 2009

Objective : This study was performed in order to figure out Oral Health Actual Condition in Elementary School Teachers in Deagu area. This study was conducted from March through May 2008. Method : A total of three hundred and ten Elementary School Teachers were surveyed. The collected data were analyzed by Oral Health Actual Condition and cognition, Diet habit or living and one's own intellect health state, Oral disease sign symptoms of percent and 2-test and One-way ANOVA test by using SPSS12.0 Program. Results : 1. The most of result Frequencies of tooth brushing per one day were 3 over 91.0% and Oral Examination, Oral Health Education need. 2. The result of oral disease sign and symptom were hypersensitivity due to cold food(39.0%), halitosis(21.6%), gingival bleeding tendency(21.3), clicking sound on TMJ(18.7%), hypersensitivity due to tooth burshing(17.1%), easy crown fracture and to be fine(10.0%), pain on TMJ or limitation of mouth opening(7.1%). 3. The most of result age a group oral hygiene assistance article age 20 for interdental tooth brushing(46.4%), age 50 over not used interdental tooth brushing 38.5%. 4. The result of sign and symptom and snack following was statistically significant(P<0.05), health of own cognition and Oral health of own cognition was statistically significant(P<0.001). Conclusion : The study of understanded the Subjective Elementary School Teachers Oral Health Actual Condition and Promotion of Oral Health follow up Oral examination and Oral Health Education have to system groping.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2019년도 추계학술대회
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• pp.107-107
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• 2019

Ulcerative colitis (UC) is one of inflammatory bowel disease (IBD), characterized by chronic inflammatory response and dysregulation of immune function. The severity of US has been influenced by environmental factors and food habit. The immune modulatory, anti-inflammatory and steroidal medicine have been used for the treatment of UC. However, long-term administration of those medicine is accompanied with side-effect. So, it is necessary to develop the non side-effect medicine using natural product. Prebiotics influences intestinal condition and food consumption. The heredity, immunity and environmental condition are related with occurrence of UC. In recent study, UC patients had lower level of prebiotics such as Lactobacillus and Bifidobacterium compared with healthy people. Also, previous study announced that imbalance of enteric flora aggravates the severity of UC. The effectiveness of probiotics might affect colon ability and viable bacteria also could promote the proliferation of beneficial intestinal bacteria. Prebiotics, such as herbal medicine, could lead to balance of intestinal bacteria or increase beneficial bacteria. So, proper choice of herbal medicine could control the intestinal condition. This study aimed to investigate the effect of mixture of probiotics and prebiotics (synbiotics) on dextran sulfate sodium (DSS)-induced UC in vivo. The synbiotics consist of Lactobacillus buchneri, Polymnia sonchifolia and Glycine max Merr. in this study. To evaluate the effect of synbiotics, 3% DSS was administered in BALB/c mice and synbiotics was daily administered for experimental days. The administration of synbiotics regulated colon length shortening, body weight change and disease activity index effectively. Also, extract of synbiotics upregulated survival ability of Lactobacillus buchneri in gut condition. These results suggest that mixture of probiotics and prebiotics, called as synbiotics, could influence intestinal condition also regulate the colon disease. Synbiotics might be a therapeutic agent for treatment of UC.

• 산업기술연구
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• 제32권A호
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• pp.15-20
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• 2012

For emergency patients as heart disease, fast treatment is very important. This paper describes a smart phone software to detect emergency circumstance and request rescue. Detection of emergency condition of heart disease patients is based on physical motion and biological heart signals as electrocardiogram. Most smart phones have three axis acceleration sensor. On emergency condition, patients remain stationary. Thus the software detect stationary condition by using acceleration sensor data. For more precise detection, it combines electrocardiogram of patients. To request rescue, it sends help messages to designated persons. In addition, it generates emergency sound to surrounding people and plays a video of emergency measure that any person on the place can help the patient temporarily.