• Title/Summary/Keyword: Discontinuation

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Geochemical Investigations of Contaminated River Waters Part II-Chemical Oxygen Demand of River Water and Industrial Waste Water in Seoul (汚濁河川水의 地球化學的인 硏究 (第 II 報) 서울市內 河川水 및 工場排水의 化學的 酸素要求量)

  • Lee, Yong-Keun
    • Journal of the Korean Chemical Society
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    • v.14 no.1
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    • pp.5-12
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    • 1970
  • River water and industrial waste water in Seoul were studied by means of chemical oxygen demand(COD) as an indicator for water pollution, from August 1967 to July 1968. Rivers flowing through residential and industrial areas are badly contaminated and COD of water in Han River increases as it progresses to downstream. Seasonal variation of COD showed that higher value of COD was observed in spring and lower in autumn. It is clear that the seasonal variation of COD is influenced by the precipitation. Close relationship was found between COD and population density. The lowest COD curve obtained by plotting COD values against population density and show that the curve slopes upward. The discontinuation of the curve was shown at the population density of 14,000/km$^2$; an increase in COD was acute over the population density of 14,000/km$^2$.

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A Case of Venlafaxine-Induced Interstitial Lung Disease

  • Oh, Serim;Cha, Seung-Ick;Kim, Hyera;Kim, Minjung;Choi, Sun Ha;Seo, Hyewon;Park, Tae-In
    • Tuberculosis and Respiratory Diseases
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    • v.77 no.2
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    • pp.81-84
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    • 2014
  • A patient treated with venlafaxine for major depression developed an interstitial lung disease (ILD) with the characteristic clinical, radiological and pathological features of chronic hypersensitivity pneumonitis. A high resolution computed tomography scan demonstrated ground glass opacity, mosaic perfusion with air-trapping and traction bronchiectasis in both lungs. The pathological findings were consistent with a nonspecific interstitial pneumonia pattern. Clinical and radiological improvements were noted after the discontinuation of venlafaxine and the administration of a corticosteroid. This report provides further evidence that the anti-depressant venlafaxine can cause ILD.

A Neurobiological Concept of Schizophrenia - Approach to Vulnerability -

  • Sato, Mitsumoto
    • Korean Journal of Biological Psychiatry
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    • v.3 no.1
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    • pp.37-45
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    • 1996
  • Recent studies on long-term outcome of schizophrenia revealed that schizophrenic symptoms recover in more than 50%, while it remains severe in less than 20% after 20 years or more from the onset. Psychopharmacological studies indicate that 75% of remitted schizophrenics may recur within 2 years after discontinuation of maintenance pharmacotherapy. In addition, family studies revealed that schizophrenic decompensation may occur significantly more frequent in discharged patients with high expressed emotion family than in low expressed emotion family. These findings strongly support a clinical validity of stress-vulnerability concept of schizophrenia which open a new viewpoint to two central problems in schizophrenia treatment, i.e. psychotic relapses and chronification of the fist episode schizophrenia. Moreover, recent psychopathological studies argue that schizophrenic symptoms are manifestations of psychological reaction secondary to a primary cognitive impairment(neurobiological vulnerability), which is originated in neurobiological changes in the brain. Recent approaches to the vulnerability to schizophrenic symptoms or schizophrenic decompensation are reviewed.

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A Study on Spatial Image Transformation by the Transparent Furniture Elements (투명가구요소에 의한 공간이미지 변화연구)

  • Kim, Jong-Seo
    • Journal of the Korea Furniture Society
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    • v.20 no.5
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    • pp.533-542
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    • 2009
  • The space is generally the discontinuation space without being understood agreed by some people. In this time, expressing transparency has various significances in furniture design because modern people want transparence and space due to the complication, numerous unreasonable facts and the lack of honesty in the society. Philip Johnson's Glass House in 1946 influenced architecture, interior, furniture and life article to use transparent materials and space that is being until currently development. The transparency which comes to be preferred clearly means to develop the society continuously. It can be more liberal, honest, and transparent society. The trend appeared in furniture design has meaning as the representative product. This research has perceptional transparency(visible transparency), abstract transparency through space(phenomenal transparency), overlap of surface element, display of line element, image using dot, and changing the image of various spaces.

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Effect of Vibramycin Precon PT-122M in urogenital infections (비뇨기과 영역에서의 Vibramycin Precon PT-122M의 효과)

  • Lim J.K.;Shin S.G.;Park C.W.;Shin S.G.
    • The Korean Journal of Pharmacology
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    • v.13 no.1 s.21
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    • pp.23-27
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    • 1977
  • To investigate the efficacy, tolerance of Vibramycin Precon PT-122 M and to determine the nature, incidence and severity of side effects of this formulation, 19 patients with urogenital infections were studied. 1. Vibramycin Precon PT-122 M reduced the signs and symptoms of various urogenital infections so as to determine the overall efficacy as good or satisfactory. 2. Intravenous injection of PT-122 M was generally well tolerated in all patients except 2 case of discontinuation because of adverse effect. 3. PT-122 M showed mild to moderate side effects but clinical features ana response to therapy were not influencea by those side effects.

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Simulation Study on the Stream Server for Deciding the Priority for Using Resources (스트림 서버에서 자원 사용 우선순위 결정을 위한 시뮬레이션 연구)

  • 박진원
    • Proceedings of the Korea Society for Simulation Conference
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    • 2003.11a
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    • pp.67-74
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    • 2003
  • Stream servers are for supplying multimedia stream data to users through the internet such as movies and musics without discontinuation. A typical stream server is designed roughly by considering the characteristics of stream services and by employing processors, memory, PCI bus, Ethernet, TOE and disks. This study focuses on deciding the priority for using resources such as PCI bus, buffer memory and TOE buffer, which have limited capacities in a typical stream server. The simulation study shows that the top priority for using PCI bus for normal streaming services should be given to the operation that sends data from buffer memory to TOE buffer Giving priority for using PCI bus to other operation such as sending data from disks to memory results in deadlock Phenomenon.

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Hepatotoxicity in an Adolescent with Black Iced Tea Overconsumption

  • Hadjipanayis, Adamos;Efstathiou, Elisavet;Papaevangelou, Vasiliki
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.22 no.4
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    • pp.387-391
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    • 2019
  • Tea is the most widely consumed beverage after water in the world. The consumption of iced tea has increased in Western countries and spiked among teenagers for enjoyment, freshening up and alertness. A teenager presented with symptoms of hepatitis. Liver ultrasound revealed sludge in the gallbladder. Laboratory investigations excluded all known causes of hepatotoxicity. Detail nutritional history revealed that the patient had been drinking 1.5-2 liters of black iced tea per day for the last three months. He was immediately advised to stop drinking any tea. Gradually all symptoms disappeared and two months after discontinuation of the tea, all liver enzymes returned to normal and the sludge in the gallbladder disappeared. This case report underlines the importance of a meticulous assessment of a child's dietary behavior when investigating a case of hepatotoxicity and raises awareness about the potential side effects of tea overconsumption.

Skin-Related Toxicity of Tyrosine Kinase Inhibitor in Thyroid Cancer (갑상선암에서 표적치료항암제의 피부 관련 부작용)

  • Lim, Dong-Jun
    • International journal of thyroidology
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    • v.11 no.2
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    • pp.82-87
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    • 2018
  • Skin-related toxicity is one of the most important adverse events from multi-target tyrosine kinase inhibitor (MTKI) to treat radioiodine refractory thyroid cancer. As hand foot skin reaction can limit quality of life and therapeutic effectiveness, it is essential to cope with a variety of severity of skin-related toxicity induced by MTKI. Herein, we will discuss two representative cases of skin-related toxicities which were managed by discontinuation/reduction of therapeutic doses of MTKI and were treated by proper medication in thyroid cancer patients with distant metastasis.

Imatinib-induced hepatitis treated by corticosteroids in a patient with metastatic gastrointestinal stromal tumor

  • Kang, Min Kyu;Lee, Heon Ju;Choi, Joon Hyuk
    • Journal of Yeungnam Medical Science
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    • v.36 no.2
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    • pp.155-158
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    • 2019
  • Imatinib mesylate is currently used as the first-line treatment for metastatic gastrointestinal stromal tumors (GISTs). Imatinib-induced hepatotoxicity in patients with GIST is very rare. Its features vary from subclinical elevation of serum aminotransferase to clinically apparent acute hepatitis, which is associated with immunologic reactions. Imatinib-induced hepatotoxicity with autoimmune-like features can be treated by the discontinuation of imatinib mesylate and the administration of oral steroids. Here, we report a case of late-onset imatinib-induced hepatitis with autoimmune-like features in a patient with metastatic GIST, which was improved by oral corticosteroids.

Apathy syndrome in a patient previously treated with selective serotonin reuptake inhibitors for depression

  • Kim, Hye-Geum;Koo, Bon-Hoon;Lee, Seung Woo;Cheon, Eun-Jin
    • Journal of Yeungnam Medical Science
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    • v.36 no.3
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    • pp.249-253
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    • 2019
  • There is considerable overlap in the clinical presentations of apathy and depression. However, differential diagnosis between apathy and other psychiatric conditions, including depression and dementia, is important. In this report, we present the case of a 67-year-old woman with a history of receiving selective serotonin reuptake inhibitor (SSRI) treatment for depression. Differential diagnosis between treatment-resistant depression and SSRI-induced apathy syndrome was required. The symptoms of her apathy syndrome were relieved after the discontinuation of SSRIs and the addition of olanzapine, methylphenidate, and modafinil. Furthermore, we briefly review related literature in this article.