• Title/Summary/Keyword: Direct Modification Method

Search Result 95, Processing Time 0.026 seconds

Detection of the Carcinogenic Liver Fluke Opisthorchis viverrini Using a Mini Parasep SF Faecal Parasite Concentrator

  • Kaewpitoon, Soraya J;Rujirakul, Ratana;Tongtawee, Taweesak;Matrakul, Likit;Panpimanmas, Sukij;Wakkuwattapong, Parichart;Loyd, Ryan A;Kaewpitoon, Natthawut
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.1
    • /
    • pp.373-376
    • /
    • 2016
  • The Mini Parasep SF fecal parasite concentrator (MPSFC) is a new modification of the closed concentration system, which can easily be adopted in any routine clinical pathology laboratory. Here we describe our experience with the system in diagnosing Opisthorchis viverrini. A total of 199 fecal samples was submitted for routine examination in the clinical pathology laboratory of Suranaree University of Technology hospital, Nakhon Ratchasima province, Thailand, during August to October 2015. Out of all samples examined, 10 (5.03%) were positive with intestinal parasites including O. viverrini (2.01%), followed by Strongyloided stercoralis (1.51%), Hookworm (0.5%), Taenia spp. (0.5%), and Entamoeba coli (0.5%). Regarding the distribution of intestinal parasites in relation to the methods used, and found that 4 samples (2.01%) were positive using the direct wet smear method while 10 (5.03%) were positive with the Mini Parasep SF method; the difference was statistically significant ($X^2$-test = 116.506, p-value =0.001). Mean time for processing using the Parasep system was 6.03 min/sample, the conventional direct wet smear method at 0.3 min/sample. Cost per test, conventional direct wet smear method costing less than the Parasep method at USD 0.74/sample versus USD 1.47/sample. This first report of O. viverrini detection using MPSFC indicates that Parasep concentration test is useful in the routine laboratory, increasing the yield of parasites as compared to direct microscopy, but with greater processing time and cost. Further comparisons between the Parasep concentration test and common methods for O. viverrini detection are required, particularly concerning use in epidemiological surveys.

Nanoparticles Synthesis and Modification using Solution Plasma Process

  • Mun, Mu Kyeom;Lee, Won Oh;Park, Jin Woo;Kim, Doo San;Yeom, Geun Young;Kim, Dong Woo
    • Applied Science and Convergence Technology
    • /
    • v.26 no.6
    • /
    • pp.164-173
    • /
    • 2017
  • Across the most industry, the demand for nanoparticles is increasing. Therefore, many studies have been carried out to synthesize nanoparticles using various methods. The aim of this paper is to introduce an industry-applicable as well as financially and environmentally effective solution plasma process. The solution plasma process involves fewer chemicals than the traditional kit, and can be used to replace many of the chemical agents employed in previous synthesis of nanoparticles into plasma. In this study, this process is compared to the wet-reaction process that has thus far been widely used in the most industry. Furthermore, the solution plasma process has been classified into four different types (in-solution, out of solution, direct type, and remote type), according to its plasma occurrence position and plasma types. Thus, the source of radicals, nanoparticle synthesis, and modification methods are explained for each design. Lastly, unlike nanoparticles with hydrophilic functional groups that are made inside the solution, a nanoparticle synthesis and modification method to create a hydrophobic functional group is also proposed.

Static and Dynamic Analysis of Plate Structures using a High Performance Finite Element (고성능 유한요소를 이용한 평판구조물의 정적 및 동적해석)

  • Han In-Seon;Kim Sun-Hoon
    • Journal of the Computational Structural Engineering Institute of Korea
    • /
    • v.18 no.3
    • /
    • pp.311-320
    • /
    • 2005
  • In this paper an enhanced quadratic finite element for static and dynamic analysis of plate structures is presented. The performance of a proposed plate element is improved by the coupled use of non conforming displacement modes, the selective integration scheme, and the assumed shear strain fields. An efficient direct modification method is also applied to this element to solve the problem such as failure of the patch test due to the adoption of non conforming modes. The proposed quadratic finite element does not show any spurious mechanism and does not produce shear locking phenomena even with distorted meshes. It is shown that the results obtained by this element converged to analytical solutions very rapidly tough numerical tests for standard benchmark problems. It is also noted that this element is applicable to transient dynamic analysis of Mindlin plates.

A Four-node General Shell Element with Drilling DOFs (면내회전자유도를 갖는 4절점 곡면 쉘요소)

  • Chung, Keun-Young;Kim, Jae-Min;Lee, Eun-Haeng
    • Journal of the Earthquake Engineering Society of Korea
    • /
    • v.16 no.4
    • /
    • pp.37-52
    • /
    • 2012
  • In this study, a new 4-node general shell element with 6 DOFs per node is presented. Drilling rotational degrees of freedom are introduced by the variational principle with an independent rotation field. In formulation of the element, substitute transverse shear strain fields are used to avoid shear locking, while four nonconforming modes are applied in the in-plane displacement fields as a remedy for membrane locking. In addition, a direct modification method for nonconforming modes is employed in the numerical implementation of nonconforming modes to represent constant strain states. A 9-points integration rule is adopted for volume integration in the computation of the element stiffness matrix. With the combined use of these techniques, the developed shell element has no spurious zero energy modes, and can represent a constant strain state. Several numerical tests are carried out to evaluate the performance of the new element developed. The test results show that the behavior of the elements is satisfactory.

Application of the Runge Kutta Discontinuous Galerkin-Direct Ghost Fluid Method to internal explosion inside a water-filled tube

  • Park, Jinwon
    • International Journal of Naval Architecture and Ocean Engineering
    • /
    • v.11 no.1
    • /
    • pp.572-583
    • /
    • 2019
  • This paper aims to assess the applicability of the Runge Kutta Discontinuous Galerkin-Direct Ghost Fluid Method to the internal explosion inside a water-filled tube, which previously was studied by many researchers in separate works. Once the explosive charge located at the inner center of the water-filled tube explodes, the tube wall is subjected to an extremely high intensity fluid loading and deformed. The deformation causes a modification of the field of fluid flow in the region near the water-structure interface so that has substantial influence on the response of the structure. To connect the structure and the fluid, valid data exchanges along the interface are essential. Classical fluid structure interaction simulations usually employ a matched meshing scheme which discretizes the fluid and structure domains using a single mesh density. The computational cost of fluid structure interaction simulations is usually governed by the structure because the size of time step may be determined by the density of structure mesh. The finer mesh density, the better solution, but more expensive computational cost. To reduce such computational cost, a non-matched meshing scheme which allows for different mesh densities is employed. The coupled numerical approach of this paper has fewer difficulties in the implementation and computation, compared to gas dynamics based approach which requires complicated analytical manipulations. It can also be applied to wider compressible, inviscid fluid flow analyses often found in underwater explosion events.

Modification of C.I. Acid Red 57 Synthesis Process (C.I. Acid Red 57의 제조공정 개선에 관한 연구)

  • Chung, Sang Woo;Kim, Jae Pil
    • Textile Coloration and Finishing
    • /
    • v.9 no.5
    • /
    • pp.75-81
    • /
    • 1997
  • o-Aminobenzene sulfone-N-ethylanilide, the diazo component of C.I. Acid Red 57, is currently being diazotised by the use of nitrosylsulphuric acid because of its high molecular weight and weak basicity. However, this method has many problems such as complicated manufacturing process and discharge of large volume of strong acidic effluent. In this study, the possibility of replacing nitrosylsulphuric acid method by direct method, which is simpler and produces less effluent, has been checked and the optimum process condition was studied. The effect of HCl concentration, the amount of sodium nitrite and particle size of diazo component on diazotisation yield was investigated. The optimum pH condition for coupling reaction was also evaluated.

  • PDF

Design of web-stiffened lipped channel beams experiencing distortional global interaction by direct strength method

  • Hashmi S.S. Ahmed;G. Khushbu;M. Anbarasu;Ather Khan
    • Structural Engineering and Mechanics
    • /
    • v.90 no.2
    • /
    • pp.117-125
    • /
    • 2024
  • This article presents the behaviour and design of cold-formed steel (CFS) web-stiffened lipped channel beams that primarily fail owing to the buckling interaction of distortional and global buckling modes. The incorporation of an intermediate stiffener in the web of the lipped channel improved the buckling performance leads to distortional buckling at intermediate length beams. The prediction of the strength of members that fail in individual buckling modes can be easily determined using the current DSM equations. However, it is difficult to estimate the strength of members undergoing buckling interactions. Special attention is required to predict the strength of the members undergoing strong buckling interactions. In the present study, the geometric dimensions of the web stiffened lipped channel beam sections were chosen such that they have almost equal distortional and global buckling stresses to have strong interactions. A validated numerical model was used to perform a parametric study and obtain design strength data for CFS web-stiffened lipped channel beams. Based on the obtained numerical data, an assessment of the current DSM equations and the equations proposed in the literature (for lipped channel CFS sections) is performed. Suitable modifications were also proposed in this work, which resulted in a higher level of design accuracy to predict the flexural strength of CFS web stiffened lipped channel beams undergoing distortional and global mode interaction. Furthermore, reliability analysis was performed to confirm the reliability of the proposed modification.

Estimation of the vibration fatigue of a linear elastic system based on a desiign sensitivity analysis (설계 만감도 해석을 활용한 선형 시스템 진동내구 평가)

  • Kim, Chan-Jung;Kim, Ku-Sik;Kang, Ho-Young;Jin, Yeo-Hwa;Lee, Bong-Hyun
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2010.10a
    • /
    • pp.491-496
    • /
    • 2010
  • The direct design modification of problematic component is disallowed in order to sacrifice other major factors such as a stability or a major performance. So, the best design policy is to risvise the immature structural medchanism under the minimal design change as soon as possible. For this paper presents a new design sensitivity analysis based on transmissibility rtio (TR) of response acceleration to find a proper candidate for the minimal design modification. The new sensitivity analysis is based on the fact that the sensitivity of TR over a small design change is inversly proportinal to the magnitude of TR. The theory of proposed design sensitivity analysis is simulated with the variance of TR over a dynamic change. Then, new methodology is appplied for a linear elastic specimen to detect the most sensitive node over a design change using measured accleration data during uni-axial vibration test, The physical verification of the sensitivity method is conducted on the CAE model of a linear elastic specimen by adding concentration mass and the vibration fatigue of the simple specimen is analyzed to estimate the relationship between fatigue behaviors and sensitivity consequences.

  • PDF

Photo-induced chemical change of di-fluoride in the CYTOP doped graphene

  • Yang, Mi-Hyun;Manoj, Sharma;Ihm, Kyuwook;Ahn, Joung Real
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2015.08a
    • /
    • pp.115-115
    • /
    • 2015
  • Many efforts have been devoted on chemical modification of graphene layer to modulate its electrical properties. In the previous report, laser irradiation on the CYTOP (Amorphous Fluoropolymer) covered graphene layer induces chemical modification wherein carbon fluoride is formed on the graphene surface. This results in the insulating I-V characteristics, which have been attracting much research interests on it. However, the direct analytical evidence of the fluoride formation on graphene surface is not yet studied. In this work we investigated what happened on the CYTOP/graphene interface during photon irradiation using spatially resolved photoemission spectroscopy method. It is found that the soft x-ray (614 eV) induces desorption of fluoride atoms from the CYTOP and change di-fluoride form to mono-fluoride. As the photo-induced fluorine desorption is continue strong dipole field generated by initial di-fluoride forms is gradually decreased, resulting in the overall binding energy shift of the C 1s core levels. Both photo-modified CYTOP and CYTOP starts to desorb above $286^{\circ}C$ (~ 0.047 eV), which means that no strong chemical interaction between CYTOP and graphene is established.

  • PDF

Structural Dynamics Optimization by Second Order Sensitivity with respect to Finite Element Parameter (유한요소 구조 인자의 2차 민감도에 의한 동적 구조 최적화)

  • Kim, Yong-Yun
    • Transactions of the Korean Society of Machine Tool Engineers
    • /
    • v.15 no.3
    • /
    • pp.8-16
    • /
    • 2006
  • This paper discusses design sensitivity analysis and its application to a structural dynamics modification. Eigenvalue derivatives are determined with respect to the element parameters, which include intrinsic property parameters such as Young's modulus, density of the material, diameter of a beam element, thickness of a plate element, and shape parameters. Derivatives of stiffness and mass matrices are directly calculated by derivatives of element matrices. The first and the second order derivatives of the eigenvalues are then mathematically derived from a dynamic equation of motion of FEM model. The calculation of the second order eigenvalue derivative requires the sensitivity of its corresponding eigenvector, which are developed by Nelson's direct approach. The modified eigenvalue of the structure is then evaluated by the Taylor series expansion with the first and the second derivatives of eigenvalue. Numerical examples for simple beam and plate are presented. First, eigenvalues of the structural system are numerically calculated. Second, the sensitivities of eigenvalues are then evaluated with respect to the element intrinsic parameters. The most effective parameter is determined by comparing sensitivities. Finally, we predict the modified eigenvalue by Taylor series expansion with the derivatives of eigenvalue for single parameter or multi parameters. The examples illustrate the effectiveness of the eigenvalue sensitivity analysis for the optimization of the structures.