• Korean Journal of Radiology
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• v.25 no.6
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• pp.540-549
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• 2024

Objective: This study investigated the feasibility and prognostic relevance of threshold-based quantification of myocardial delayed enhancement (MDE) on CT in patients with nonischemic dilated cardiomyopathy (NIDCM). Materials and Methods: Forty-three patients with NIDCM (59.3 ± 17.1 years; 21 male) were included in the study and underwent cardiac CT and MRI. MDE was quantified manually and with a threshold-based quantification method using cutoffs of 2, 3, and 4 standard deviations (SDs) on three sets of CT images (100 kVp, 120 kVp, and 70 keV). Interobserver agreement in MDE quantification was assessed using the intraclass correlation coefficient (ICC). Agreement between CT and MRI was evaluated using the Bland-Altman method and the concordance correlation coefficient (CCC). Patients were followed up for the subsequent occurrence of the primary composite outcome, including cardiac death, heart transplantation, heart failure hospitalization, or appropriate use of an implantable cardioverter-defibrillator. The Kaplan-Meier method was used to estimate event-free survival according to MDE levels. Results: Late gadolinium enhancement (LGE) was observed in 29 patients (67%, 29/43), and the mean LGE found with the 5-SD threshold was 4.1% ± 3.6%. The 4-SD threshold on 70-keV CT showed excellent interobserver agreement (ICC = 0.810) and the highest concordance with MRI (CCC = 0.803). This method also yielded the smallest bias with the narrowest range of 95% limits of agreement compared to MRI (bias, -0.119%; 95% limits of agreement, -4.216% to 3.978%). During a median follow-up of 1625 days (interquartile range, 712-1430 days), 10 patients (23%, 10/43) experienced the primary composite outcome. Event-free survival significantly differed between risk subgroups divided by the optimal MDE cutoff of 4.3% (log-rank P = 0.005). Conclusion: The 4-SD threshold on 70-keV monochromatic CT yielded results comparable to those of MRI for quantifying MDE as a marker of myocardial fibrosis, which showed prognostic value in patients with NIDCM.

• Korean Journal of Radiology
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• v.24 no.5
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• pp.395-405
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• 2023

Objective: This study aimed to develop and validate models using radiomics features on a native T1 map from cardiac magnetic resonance (CMR) to predict left ventricular reverse remodeling (LVRR) in patients with nonischemic dilated cardiomyopathy (NIDCM). Materials and Methods: Data from 274 patients with NIDCM who underwent CMR imaging with T1 mapping at Severance Hospital between April 2012 and December 2018 were retrospectively reviewed. Radiomic features were extracted from the native T1 maps. LVRR was determined using echocardiography performed ≥ 180 days after the CMR. The radiomics score was generated using the least absolute shrinkage and selection operator logistic regression models. Clinical, clinical + late gadolinium enhancement (LGE), clinical + radiomics, and clinical + LGE + radiomics models were built using a logistic regression method to predict LVRR. For internal validation of the result, bootstrap validation with 1000 resampling iterations was performed, and the optimism-corrected area under the receiver operating characteristic curve (AUC) with 95% confidence interval (CI) was computed. Model performance was compared using AUC with the DeLong test and bootstrap. Results: Among 274 patients, 123 (44.9%) were classified as LVRR-positive and 151 (55.1%) as LVRR-negative. The optimism-corrected AUC of the radiomics model in internal validation with bootstrapping was 0.753 (95% CI, 0.698-0.813). The clinical + radiomics model revealed a higher optimism-corrected AUC than that of the clinical + LGE model (0.794 vs. 0.716; difference, 0.078 [99% CI, 0.003-0.151]). The clinical + LGE + radiomics model significantly improved the prediction of LVRR compared with the clinical + LGE model (optimism-corrected AUC of 0.811 vs. 0.716; difference, 0.095 [99% CI, 0.022-0.139]). Conclusion: The radiomic characteristics extracted from a non-enhanced T1 map may improve the prediction of LVRR and offer added value over traditional LGE in patients with NIDCM. Additional external validation research is required.

• Journal of Chest Surgery
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• v.12 no.1
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• pp.67-74
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• 1979

Esophagocardiomyotomy [modified Heller procedure] is a widely accepted operation for relief of dysphagia in patient with esophageal achalasia. But patients with advanced achalasia were more likely to get poorer results from a modified Heller myotomy because of the dependent pouch that creates an angulation at the junction of thick-walled dilated esophagus with the thin wailed aganglionic segment and hinders complete emptying. Thorbjarnarson[1975] proposed the method including truncal vagectomy and pyloroplasty. Vagectomy and pyloroplasty should lesson the severity of acid-peptic esophagitis, if reflux should occur postoperatively. Here we presented 4 cases esophageal achalasia treated by modified Heller operation of 3 cases and one case of Thorbjarnarson method. All postoperative results are good.

• Journal of Chest Surgery
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• v.20 no.3
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• pp.619-623
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• 1987

We experienced a surgical case of esophageal atresia and tracheoesophageal fistula combined with imperforated anus, tracheal bronchus in a one day baby. A vacuum delivered full term baby, weighing 4.1 Kg showed grunting respiration, repeated regurgitation and distended abdomen after birth. Esophagogram revealed markedly dilated proximal esophagus as blind pouch and also noted displaced type of tracheal bronchus of right upper lobe by incidental bronchogram. Surgical correction with Haight anastomosis was performed successfully on the second day.

• Journal of the Korean Institute of Navigation
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• v.19 no.3
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• pp.21-28
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• 1995

Mathematical morphology skeleton image processing makes many partial skeleton image planes from an original binary image. And the original binary image can be reconstructed without any distortion by summing the first partial skeleton image plane and each dilated partial skeleton image planes using the same structuring element. Especially compression effects of Elias coding to the morphological globally minimal skeleton(GMS) image, is better than that of PCX and Huffman coding. And then this paper proposes mathematical morphological GMS image processing which can be applied to a binary image transmitting for facimile and big size(bigger than $64{\times}64$ size) bitmap fonts storing in a memory.

• 대한핵의학회:학술대회논문집
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• 2005.11a
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• pp.345.1-345.1
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• 2005

• Journal of the Korean Data and Information Science Society
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• v.21 no.4
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• pp.777-782
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• 2010

We introduce some techniques to decompose the impulse (the unit sample) into several dilated pieces in the discrete time domain. From the decomposition of the impulse, we obtain localized moving averages. Thus we construct hybrid Bollinger bands that may give various strategies for stock traders. By simulations, we report that more than 94% of stock prices of companies in KOSPI 200 are inside this hybrid Bollinger band.

• Plant Resources
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• v.1 no.2
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• pp.121-125
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• 1998

Wood and bark structure of Laurus, which is considered as an important spice resources was characterized by several transitional and advanced features. Annual rings are distinct: vessel elements are moderately short and narrow, both simple and sealariform perforation plates. alternate intervascular pitting; irregularly septate fiber are present; parenchyma strands are scanty paratracheal: rays are both homogeneous and heterogeneous with multiseriate: phloem rays are dilated. Comparisons with other genera of Lauraceae suggest that Laurus is transitional and advanced state in evolutionary trends in the family.

• Journal of Chest Surgery
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• v.19 no.1
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• pp.160-164
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• 1986

Tetralogy of Fallot with absent pulmonic valve is a rare cardiac malformation. The most significant symptoms during early infancy are secondary to bronchial compression resulting from the dilated pulmonary arteries. The clinical diagnosis was confirmed by echocardiography, cardiac catheterization and cardioangiography. A case of TOF with absent pulmonic valve was successful operated upon without insertion of the pulmonic valve. The narrow pulmonic valve annulus was enlarged with a transannular pericardial patch graft. The postoperative course was uneventful.

• Journal of the Korean Mathematical Society
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• v.59 no.5
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• pp.997-1013
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• 2022

In this paper we give conditions on a matrix which guarantee that it is similar to a centrosymmetric matrix. We use this conditions to show that some 4 × 4 and 6 × 6 Toeplitz matrices are similar to centrosymmetric matrices. Furthermore, we give conditions for a matrix to be similar to a matrix which has a centrosymmetric principal submatrix, and conditions under which a matrix can be dilated to a matrix similar to a centrosymmetric matrix.