• 대한핵의학회지
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• 제24권2호
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• pp.332-336
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• 1990

Pheochromocytoma occurs at all ages but is most common in young to midadult life. In adults 10 percent of pheochronocytoma are bilateral. And bilateral lesions are common in the familial syndromes; within Multiple Endocrine Neoplasia (MEN) kindreds over half with pheochromocytomas have bilateral lesions. We report a case of bilateral pheochromocytoma firstly detected by ultrasonogram. This 24-year-old male was normotensive and had symptoms of dilated cardiomyopathy and elevated VMA level. CT and MRI were performed to evaluate the tissue nature and associated abnormalities. $^{131}I-MIBG$ scan seems to be the imaging of choice in patients with suspected multicentric/bilateral or recurrent or metastatic pheochromocytomas.

• Journal of Chest Surgery
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• 제53권2호
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• pp.79-81
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• 2020

Treatment options for children with end-stage heart failure are limited. We report the first case of a successful pediatric heart transplantation bridged with a durable left ventricular assist device in Korea. A 10-month-old female infant with dilated cardiomyopathy and left ventricular non-compaction was listed for heart transplantation. During the waiting period, the patient's status deteriorated. Therefore, we decided to provide support with a durable left ventricular assist device as a bridge to transplantation. The patient was successfully bridged to heart transplantation with effective support and without any major adverse events.

• Applied Microscopy
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• 제22권2호
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• pp.127-140
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• 1992

This research was undertaken to determine the effects of the cyclophosphamide (CP) on the epididymal corpus of the male rat in terms of ultrastructural alteration and protein analysis by SDS-PAGE at different groups; control group, 1 week group, 3 weeks group and 5 weeks group were treated with saline (control group) or CP at doses of 20mg/kg/week, 1 time a week, respectively. In the cytoplasm of the principal cells on the epididymal corpus, the mitochondria were significantly swollen or disrupted. The lumens of rough endoplasmic reticulum (rER) were also dilated and the number of secretory vesicles and lysosomes were increased respectively. CP caused changes in protein concentrations in the corpus of epididymis after CP treatment. Total proteins of 31 to 36 species were expressed in the corpus fluid. Then the more CP was increased, the more concentration of proteins caused to decrease, synthesize or increase in epididymal corpus. In contrast to the control group, in particular 88KD and the other 8 proteins in the corpus fluid, were decreased or disappeared respectively, whereas acid phosphatase and the other 9 proteins in the corpus fluid, were increased or synthesized respectively. The other proteins are not showed distinctive difference. It is suggested that treatment with CP alters the specific cell organelles and proteins in segment of the epididymal corpus.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1972년도 춘계종합 학술대회 초록집
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• pp.16.3-17
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• 1972

본원 이비인후과에서 Achalasia(무이완증)라고 진단한 1예의 환자에 대하여 Mercury bongienage를 실시하여 좋은 치료 효과를 보았기에 보고하는 바이다. 본 환자는 25세의 처녀로써 5년 전부터 식후 흉골하불경감과 타액과다 등이 있어 약 이년 전에 모병원 내과에서 진찰결과 전폐에 심한 건성잡음을 지닌 기관지 천식이라는 추정하에 치료하였으나 포말상백색타액과 호흡곤란, 소화불량, 해수, 연하장애 등의 증상이 계속되어 본과에 문진해 와서 입원 후 Esophagography와 Esophagoscopy를 실시하였다. 그 결과 Esophagogram상 분문부의 심한 협착과 그 상부의 심한 확장을 볼 수 있었고, Esophagoscopy시 분문부에서는 관강을 찾을 수 없었고 그 대신 증대된 mocosal fold를 볼 수 있었고 식도벽의 궤양이나 종물은 발견할 수 없었다. 약 1개월간의 mercury fougienage 결과 많은 증세의 호전이 있었으며 육개월이 지난 현재도 양호한 상태로 특별한 호소없이 지내고 있다.

• 한방안이비인후피부과학회지
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• 제17권3호
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• pp.167-173
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• 2004

Strabismus is a misalignment of the eyes. It is divided into paralytic strabismus and non-paralytic strabismus. There are so many causes in paralytic strabismus, and the oculomotor nerve palsy is one of them. Many studies reported the etiology and clinical features of oculomotor nerve palsy. Common causes of oculomotor nerve palsy are idiopathic, vascula.; disease, aneurysm, head trauma, neoplasm and miscellaneous. Recently the proportion of traumatic cause has been increased, but the treatment is difficult as it used to be. In this case report, one case of traumatic oculomotor nerve palsy with zygomatic arch Fx and clavicle Fx were treated by herbal medicine and acupuncture. After Treatment, symptoms- ptosis, deviation of Lt. eye to downward & outward in primary position, diplopia, limited adduction & elevation & depression, dilated pupil without pupil reflex- were improved. There are so many hypothesises but no definite guide lines are established about the oriental medical treatment of oculomotor nerve palsy, so we expect the establishment of definite guide lines by further clinical studies.

• 한방안이비인후피부과학회지
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• 제21권1호
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• pp.16-25
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• 2008

Background & Objectives : Rhinitis is an inflammation of nasal mucosa. The major symtoms are watery rhinorrhea, sneezing, itchy nose, and nasal obstruction. Allergic rhinitis is an immune reaction by allergen. So, we aimed to determine therapeutic effects of Acorus gramineus by observing changes in IL-4, $IFN-{\gamma}$ and the nasal mucosal tissue. Materials and Methods : Fifteen BALC/c mice were divided into three groups : m group(which ate low concentrated herbal medicine ), M group(which ate high concentrated herbal medicine) and control group. Control and experimental group were induced allergic rhinitis by Ovalbumin as the method of Levin and Vaz. Experimental group was orally administered the Acorus gramineus extract for 28days. We observed changes in IL-4, $IFN-{\gamma}$ and trans aminase(AST, ALT) in blood and nasal mucosa and submucosa. Results : There were no significant changes statistically in IL-4 and $IFN-{\gamma}$ in blood(p<0.05). And there were no hepatotoxicity with Acorus gramineus extract. Histologically, almost no inflammatory response in treatment group(m,M) against that there were inflammatory response(increased goblet cells, dilated vessels, edema of bowman's glands and injured olfactory hairs) in control group. Conclusion : According to above results, it is supposed that Acorus gramineus has no immunological effects on allergic rhinitis.

• 한국임상수의학회지
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• 제22권3호
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• pp.281-283
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• 2005

A 3-month-old male, Cocker Spaniel with persistent regurgitation immediately after weaning and stunted growth was referred. Radiographic findings on the lateral view include ventral deviation of the thoracic trachea caused by draping of the dilated esophagus and a distinct interface of the dorsal wall of the esophagus silhouetting with the cranial thoracic hypaxial muscles. On the ventrodorsal view, the cranial mediastinum was widened with soft tissue opacity. The trachea was deviated to the right. In an esophagogram, the segmental dilation of the esophagus with constriction of the lumen just cranial to the heart base was identified. In a fluoroscopic examination, the contrast medium was massively accumulated in the cranial portion of the constricted esophagus. At surgery, it was confirmed that the esophageal tract was constricted at the cranial to the base of the heart by aberrant right subclavian artery. It was ligated and divided surgically. Current state of the referred is maintained normal condition from the surgical repair.

• 한국통신학회논문지
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• 제21권7호
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• pp.1696-1705
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• 1996

중앙값여파기의 일반화된 형태인 스택여파기의 이론을 써서 잡음으로 왜곡된 영상에서의 윤곽선 검출기를 연구하였다. 이 논문에서 제안된 추정값 차이기법(difference of estimates:DoE)은 충격성 잡음의 환경에서 매우 효율적인 기법으로 기존의 형태학적 접근 방법을 개선하였다고 할 수 있다. 이 기법에서는 잡음이 있는 영상에 스택필터를 사용하여 잡음이 없는 원영상의 불림 영상(diated version)과 녹임 영상(eroded version)을 최적으로 추정한다. 그 결과로 얻어진 추정 영상의 차이에 적절한 문턱값 연산을 적용하여 윤곽선을 얻을 수 있다. 이 기법을 써서 얻은 결과는 가산상 정규 잡음의 경우에는 Canny의 기법을 이용하여 얻은 결과와 상응하는 성능을 갖고, 충격성 잡음의 경우에는 훨씬 좋은 성능을 보여준다.

• 약학회지
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• 제39권6호
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• pp.600-609
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• 1995

Studies on the pharmaco-constituents from the leaves of Cercts chinensis which have been used for the treatment of inflammation, contusion, dilated blood, pain of heart and stomach, edema, etc. in Korean folk remedies were carried out. Dried leaves of the plant were extracted with MeOH. The MeOH extract was suspended in distilled water and subsequently fractionated with $Et_{2}O$ and n-BuOH. From the $Et_{2}O$ and n-BuOH fractions, six phenolic compounds were isolated and identified as myricitrin($C_{21}H_{20}O_{12}, {\;}m.p.{\;}199~200^{\circ}$. $4myricetin-3-O-{\alpha}-L-rhamnopyranoside$), kaempferol($C_{15}H_{10}O_{6}, {\;}m.p. 276^{\circ}$), quercetin($C_{15}Ha_{10}O_{7}, {\;}m.p.{\;}313~314^{\circ}$), quercitrin ($C_{21}H_{20}O_{12}, {\;}m.p.{\;}176~178^{\circ}, {\;}quercetin-3-O-{\alpha}-L-rhamnopyranoside$), gallicin ($C_{8}H_{8}O_{5}, {\;}m.p.{\;}202~203^{\circ}$. methyl gallate), gallic acid ($C_{7}H_{6}O_{5}, {\;}m.p.{\;}260~265^{\circ}) through their physico-chemical data and UV, IR, EI-MS, $^{13}C-NMR$, and $^{1}H-NMR$ analysis with authentics.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권3호
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• pp.85-93
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• 2014

Purpose: Nodal metastasis is the main prognostic factor in the patients with oral squamous cell carcinoma (OSCC). We investigated the association between tumor-associated lymphatics and OSCC characteristics. Methods: Thirty-four specimens were used for the immunohistochemical staining with the antibody for vascular endothelial growth factor (VEGF)-C, VEGF-D, VEGF receptor (VEGFR)-3, phosphorylated VEGFR-3, D2-40, and matrix metallproteinases (MMPs). We observed the distribution of the lymphangiogenic factors and quantified the degree of expression. We determined lymphatic vessel density (LVD) and lymphatic vessel dilatation with D2-40 immunostaining. We assessed the association of LVD or lymphatic vessel dilatation with tumor progression or tumor differentiation. Results: OSCC cells expressed lymphangiogenic ligands. Lymphangiogenic receptor, VEGFR-3, was expressed and activated in some tumor cells as well as in tumor-associated endothelial cells. LVD was not associated with tumor size or nodal status, but lymphatic vessel dilatation was higher in tumors with nodal metastasis, and also higher in poorly differentiated tumors. In stromal area of OSCC, MMP-1 and MMP-10 were up-regulated and the basement membrane of tumor-associated endothelial cells was destroyed by these collagenases. Conclusion: In the primary tumors with nodal metastasis, especially in poorly differentiated OSCC, tumor cells invaded the dilated lymphatic vessels via ruptured sites. MMP-1 and MMP-10 are important in the lysis of the glycocalyx inside the tumor-associated lymphatic endothelial cells.