• Proceedings of the Korean Society of Computer Information Conference
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• 2018.07a
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• pp.63-66
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• 2018

스팸 스미싱 SMS의 차단을 위하여 지금까지 다양한 차단기법이 개발되어 사용되고 있다. 그 중에서도 대부분을 차지하는 방법들이 기계학습을 통한 내용 기반의 차단과 사용자의 스팸신고를 통한 송신자 차단 방법이다. 그러나 이러한 방법들은 공통적으로 스팸 스미싱을 식별하기 위해 학습 데이터가 필요하다는 문제점을 갖고 있기 때문에, 신종 스팸 공격들은 차단이 불가능하여 차단율의 한계를 보인다. 본 논문에서는 오늘날 사용되고 있는 스팸 스미싱 차단 기법들의 근본적인 문제점들을 규명하고, 이를 해결할 수 있는 스팸차단 기법 중 하나인 송신자 자가인증 기법을 소개한다. 그리고 송신자 자가인증 기법을 적용한 안드로이드애플리케이션의 구현 및 동작과정을 설명한다.

• International Journal of Stem Cells
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• v.17 no.1
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• pp.51-58
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• 2024

With the activity of intestinal stem cells and continuous turnover, the gut epithelium is one of the most dynamic tissues in animals. Due to its simple yet conserved tissue structure and enteric cell composition as well as advanced genetic and histologic techniques, Drosophila serves as a valuable model system for investigating the regulation of intestinal stem cells. The Drosophila gut epithelium is in constant contact with indigenous microbiota and encounters externally introduced "non-self" substances, including foodborne pathogens. Therefore, in addition to its role in digestion and nutrient absorption, another essential function of the gut epithelium is to control the expansion of microbes while maintaining its structural integrity, necessitating a tissue turnover process involving intestinal stem cell activity. As a result, the microbiome and pathogens serve as important factors in regulating intestinal tissue turnover. In this manuscript, I discuss crucial discoveries revealing the interaction between gut microbes and the host's innate immune system, closely associated with the regulation of intestinal stem cell proliferation and differentiation, ultimately contributing to epithelial homeostasis.

• Journal of Digital Convergence
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• v.17 no.3
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• pp.13-23
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• 2019

The purpose of this study is to investigate the effects of Characteristics of Entrepreneurship Education Program on Perceived Feasibility, Entrepreneurship, Career Decision Self-Efficacy and Entrepreneurial intention. A total of 559 questionnaires were collected from students participating in the BizCool Camp, were classified as SPSS 21.0 And Amos 22.0. As a result of the hypothesis test, the Characteristics of Entrepreneurship Education Program(Entrepreneurship Education Expertise, Differentiation of Entrepreneurship Education) positively affect Perceived Feasibility and Entrepreneurship, and Perceived Feasibility and Entrepreneurship increase Entrepreneurial Intention through Career Decision Self-Efficacy. This study proves that Entrepreneurship Recognition should be formed in order for The Youth Entrepreneurship Education Program to be Startups.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.9 no.2
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• pp.213-225
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• 2002

The purpose of this study was to identify the Effect of Hand Reflexology on Saeng-chi of physiologic, emotional & motivational responses and Immunity in ESRD patients who received hemodialysis in two general hospital from June to September. 2001 A two group quasi-experimental research with pre and post test design was used. The number of participants in the experimental group was 23, and in the control group, 20 The Hand Reflexology Intervention was developed by the researcher based on hand reflexology by Carter & Weber and Chi-massage by Chia. The Hand Reflexology was applied to both hands for 10 minutes per day. and 5 days by 5 times. To evaluate the effects of the program, Pre and Post evaluations were done. In the physiologic response, the PR was decreased at the 1st times post treatment and at the 5th. In addition BP was decreased at the 1st time, but not the 5th. After 5 treatments, there were significant increase in Hb and significant decreases in the BUN and Cr. levels in the experimental group. In the emotional and motivational responses, there were significant increases in vigor, mood, uplifts and self care agency scores in the experimental group, but there was no significant difference in the Rosenberg's self esteem score. In the experimental group, significantly increased CD4, and h/s ratios were found, also NK cells were significantly decreased, and there was a decrease in the CD8. However, no significant differences between groups were observed. There were significant increases in CD32, CD33, CD34 in the experimental group. The self care agency score correlated negatively with the CD8. From the above results, Hand Reflexology is shown to be an effective mind-body nursing intervention for enhancing Saeng-chi responses and affecting some of the immune responses. However, Immune cell activation and differentiation with hand reflexology will be achieved with future study.

• Molecules and Cells
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• v.38 no.3
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• pp.195-201
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• 2015

Antibodies are powerful defense tools against pathogens but may cause autoimmune diseases when erroneously directed toward self-antigens. Thus, antibody producing cells are carefully selected, refined, and expanded in a highly regulated microenvironment (germinal center) in the peripheral lymphoid organs. A subset of T cells termed T follicular helper cells (Tfh) play a central role in instructing B cells to form a repertoire of antibody producing cells that provide life-long supply of high affinity, pathogenspecific antibodies. Therefore, understanding how Tfh cells arise and how they facilitate B cell selection and differentiation during germinal center reaction is critical to improve vaccines and better treat autoimmune diseases. In this review, I will summarise recent findings on molecular and cellular mechanisms underlying Tfh generation and function with an emphasis on T cell costimulation.

• The Journal of Korean Medicine
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• v.33 no.4
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• pp.81-85
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• 2012

Objectives: To describe a clinical case of a patient with chronic fatigue syndrome (CFS) who was cured using indirect moxibustion. Methods: A male patient with severe CFS was treated with mainly indirect moxibustion (KI1, CV4 and CV8). The clinical outcome was observed by self-reporting, both visual analogue scale (VAS) and numerical rating scale (NRS). Results: The patient's symptoms matched the criteria for CFS diagnosis. His symptom differentiation was the "Yang deficiency of spleen and kidney". The fatigue feeling and related-symptoms were radically reduced by 14-day treatment. The VAS and NRS score changed from 8.5 and 70 to 3.5 and 35, respectively. Conclusions: This case report provides information on the potential of moxibustion therapy and its application for CFS and fatigue-associated disorders.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2008.05a
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• pp.232-235
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• 2008

This study aims to propose the residential service for Active senior from the age of 40's to 60's who prefers urban-type lifestyle. The lifestyle for Active senior was reorganized into the 5 main categories; convenience, well-being & activity, community, brand & Individuality and self-expression from the recent studies about the senior lifestyle. According to the lifestyle above, I propose the residential services to meet their needs. The result of the research, it showed that the services comcerned about the lifestyle; one stop living service, customized activity & health program, open community, various choices & facility differentiation and life-long education & working opportunity can be possible and more helpful in meeting the active senior's needs.

• Bulletin of the Korean Mathematical Society
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• v.52 no.4
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• pp.1383-1399
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• 2015

Let ${\mathbb{D}}=\{z{\in}{\mathbb{C}}:{\mid}z{\mid}<1\}$ be the open unit disk in the complex plane $\mathbb{C}$, ${\varphi}$ an analytic self-map of $\mathbb{D}$ and ${\psi}$ an analytic function in $\mathbb{D}$. Let D be the differentiation operator and $W_{{\varphi},{\psi}}$ the weighted composition operator. The boundedness and compactness of the product-type operator $W_{{\varphi},{\psi}}D$ from the weighted Bergman-Orlicz space to the weighted Zygmund space on $\mathbb{D}$ are characterized.

• Biomolecules & Therapeutics
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• v.21 no.3
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• pp.196-203
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• 2013

Recent accumulating studies have reported that hypoxic preconditioning during ex vivo expansion enhanced the self-renewal or differentiation of various stem cells and provide an important strategy for the adequate modulation of oxygen in culture conditions, which might increase the functional bioactivity of these cells for cardiac regeneration. In this study, we proposed a novel priming protocol to increase the functional bioactivity of cardiac progenitor cells (CPCs) for the treatment of cardiac regeneration. Firstly, patient-derived c-$kit^+$ CPCs isolated from the atrium of human hearts by enzymatic digestion and secondly, pivotal target molecules identified their differentiation into specific cell lineages. We observed that hCPCs, in response to hypoxia, strongly activated ERK phosphorylation in ex vivo culture conditioning. Interestingly, pre-treatment with an ERK inhibitor, U0126, significantly enhanced cellular proliferation and tubular formation capacities of CPCs. Furthermore, we observed that hCPCs efficiently maintained the expression of the c-kit, a typical stem cell marker of CPCs, under both hypoxic conditioning and ERK inhibition. We also show that hCPCs, after preconditioning of both hypoxic and ERK inhibition, are capable of differentiating into smooth muscle cells (SMCs) and cardiomyocytes (CMs), but not endothelial cells (ECs), as demonstrated by the strong expression of ${\alpha}$-SMA, Nkx2.5, and cTnT, respectively. From our results, we conclude that the functional bioactivity of patient-derived hCPCs and their ability to differentiate into SMCs and CMs can be efficiently increased under specifically defined culture conditions such as short-term hypoxic preconditioning and ERK inhibition.

• Advances in pediatric surgery
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• v.11 no.1
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• pp.1-8
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• 2005

With the development of fetal ultrasonography, detection of fetal ovarian cysts has been increased. Although ovarian cyst formation during the perinatal period is a self limiting process, there is still considerable controversy regarding the best treatment of the fetal ovarian cyst. The purpose of this study is to evaluate the natural history of fetal ovarian cysts and to analyze the result of treatment. From 1995 to 2004, 31 consecutive fetuses with ovarian cysts were followed by ultrasonography during the perinatal period. The fetal ovarian cyst was diagnosed by prenatal ultrasonography between 25weeks and 38 weeks and the mean size of the cysts was 5cm (ranged from 2 to 8cm). At birth, 3 cysts disappeared. In 2 cases, the diagnoses were changed to multicystic kidney disease and intestinal duplication. During following up of 26 cysts, 15 cysts have resolved completely. Seven cysts required oophorectomy because of cyst torsion (n=3), differentiation of tumorous condition (n=2), increased size of cyst (n=1), and large size (8cm) of cyst at birth (n=l). Fetal ovarian cyst should primarily be observed, and only in the limited cases, surgical treatment would be required for the risk of complications such as torsion and differentiation from benign to malignant pathology.