• 제목/요약/키워드: Differentially

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Detecting differentially expressed genes from a mixed data set

  • Lee, Sun-Ho;Kim, In-Young;Kim, Sang-Cheol;Rha, Sun-Young;Chung, Hyun-Chel;Kim, Byung-Soo
    • 한국통계학회:학술대회논문집
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    • 한국통계학회 2003년도 추계 학술발표회 논문집
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    • pp.173-177
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    • 2003
  • When we have both a paired data set and two independent data sets, neither a paired t-test nor a two-sample t-test can be used to detect differences between two samples. In order to identify differentially expressed genes in a mixed data set, a new test statistic is proposed.

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차동 연결된 Varactor를 이용한 6Gbps CMOS 피드포워드 이퀄라이저 (A 6Gbps CMOS Feed-Forward Equalizer Using A Differentially-Connected Varactor)

  • 문용삼
    • 대한전자공학회논문지SD
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    • 제46권2호
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    • pp.64-70
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    • 2009
  • 0.13-um CMOS 공정을 이용하여 3GHz에서 6.2dB의 gain을 갖는 피드포워드 이퀄라이저를 구현하고 14.7dB의 감쇄를 갖는 7-m SATA 케이블을 통해 6Gbps의 데이터를 에러 없이 복원하였다. 제안한 이퀄라이저 회로는 varactor의 차동 연결을 통해서 기존 이퀄라이저에서 사용되는 varactor 면적의 1/4만을 사용하도록 설계되어 pad-frame에 집적할 수 있을 뿐만 아니라, 높은 동작 주파수 및 3.6mW의 낮은 전력 소모를 유지할 수 있다.

중하중을 받는 이동로붓의 슬라이딩모드 제어 (Sliding Mode Control for a High-Load Wheeled Mobile Robot)

  • 홍대희;정재훈
    • 한국정밀공학회지
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    • 제17권5호
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    • pp.145-153
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    • 2000
  • This paper discusses the dynamic modeling and robust control development for a differentially steered mobile robot subject to wheel slip according to high load. Consideration of wheel slip is crucial for high load applications such as construction automation tasks because wheel slip acts as a severe disturbance to the system. It is shown that the uncertainty terms due to the wheel slip satisfy the matching condition for the sliding mode control design. From the full dynamic model of the mobile robot, a reduced ideal model is extracted to facilitate the control design. The sliding mode control method ensures the dynamic tracking performance for such a mobile robot. Numerical simulation shows the promise of the developed algorithm.

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미분적으로 평활한 불확정 비선형 시스템의 강인 안정화 (Robust Stabilization of Differentially Flat Uncertain Nonlinear Systems)

  • 주진만;박진배;최윤호;윤태성
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1998년도 하계학술대회 논문집 B
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    • pp.647-649
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    • 1998
  • This paper describes a robust stabilization of single input nonlinear systems with parametric uncertainty. We first investigate differential flatness of the nominal nonlinear systems. If a single input system is differentially flat, it possesses a flat output. And we define coordinate transformation functions via successively differentiating the flat output, and we also consider the robust fictitious controls at every differentiation of the flat output. In the new coordinates the nonlinear system is transformed into the Brunovsky normal form with matched uncertainty. With a robust control based on the Lyapunov method, the robust stabilization is achieved.

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Several Genes Expressed During Morphogenesis of Lentinus edodes(ImHyup-1)

  • Lee, Sang-Sun;Hong, Sung-Woon;Kim, Seung-Hae;Kim, Bong-Cheol
    • Mycobiology
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    • 제29권3호
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    • pp.135-141
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    • 2001
  • Differential display of reverse transcription(DDRT)-PCR was conducted to have a profile of the differentially expressed genes during the formation of fruiting body of Lentinus edodes. The lines of L. edodes(ImHyup-1) employed were cultivated in the artificial blocks of sawdust, and the fruiting body was induced from the mycelia or the mass protruded from the brown surface of the sawdust blocks. RNAs were prepared from the four different developmental stages; mycelial, primordial, and stipes and pileus of fruiting body. The fragments of cDNA were synthesized from the combinations of the arbitrary primers and 3' one anchored Oligo-dT primer. Twelve combinations using the primers have been tested, and among them nineteen bands were identified as differentially expressed. Those genes were further analyzed by DNA sequencing and followed by homology search. Characterization of one clone was conducted as a preliminary data and more are under investigation.

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Differential Responses of Large and Small Male Red-spotted Newts, Notophthalmus viridescens, to Conspecific Chemical Cues

  • Park, Dae-Sik;Jeanette M., Mc-Guire;Heather L., Eisthen
    • Animal cells and systems
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    • 제8권2호
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    • pp.81-87
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    • 2004
  • Male red-spotted newts, Notophthalmus viridescens, use chemical cues to locate and select potential mates. To investigate whether large and small males respond differentially to chemical cues from conspecifics, we conducted a series of two-choice Y-maze tests with odorant stimuli from two large females (LF/LF), one large versus one small female (LF/SF), and one large female placed with four males versus one small female (LF+4M/SF). We found that males responded more rapidly in a LF/LF choice situation than in those involving LF/SF or LF+4M/SF. In addition, small males chose more quickly than did large males. These results suggest that both body size and odorant context affect the speed of odorant responses. By responding differentially to conspecific chemical cues, small males may arrive earlier at a courting area, increasing their chances of successfully guarding and mating with a female.

Korean Retailers' Dependence Level: The Impact of Power Sources, Satisfaction, Conflict, and Long-Term Orientation

  • Yu, Jong-Pil;Pysarchik, Dawn Thorndike;Kim, Yu-Kyung
    • 마케팅과학연구
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    • 제18권1호
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    • pp.81-114
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    • 2008
  • The purpose of this study was to analyze how economic factors (economic satisfaction, economic conflict) and non-economic factors (non-economic satisfaction, non-economic conflict) differentially influence Korean retailers' long-term orientation with manufacturers, and how they are influenced by manufacturers' power sources under different levels of retailer dependence. After Korean retailers were divided into high and low dependence groups, path differences between the two groups were compared. The results suggested that manufacturers' coercive and non-coercive power sources do not differentially influence high and low dependence retailers' economic and non-economic satisfaction, and economic and non-economic conflict. However, the economic satisfaction of low dependence retailers more strongly affects their long-term orientation than that of high dependence retailers. Also, the economic conflict of highly dependent retailers more strongly affects their long-term orientation as compared to low dependence retailers. Finally, the impact of non-economic conflict negatively influences a long-term orientation for both retailer groups.

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In silico Identification of SFRP1 as a Hypermethylated Gene in Colorectal Cancers

  • Kim, Jongbum;Kim, Sangsoo
    • Genomics & Informatics
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    • 제12권4호
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    • pp.171-180
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    • 2014
  • Aberrant DNA methylation, as an epigenetic marker of cancer, influences tumor development and progression. We downloaded publicly available DNA methylation and gene expression datasets of matched cancer and normal pairs from the Cancer Genome Atlas Data Portal and performed a systematic computational analysis. This study has three aims to screen genes that show hypermethylation and downregulated patterns in colorectal cancers, to identify differentially methylated regions in one of these genes, SFRP1, and to test whether the SFRP genes affect survival or not. Our results show that 31 hypermethylated genes had a negative correlation with gene expression. Among them, SFRP1 had a differentially methylated pattern at each methylation site. We also show that SFRP1 may be a potential biomarker for colorectal cancer survival.

Inversion-Based Robust Output Tracking of Differentially Flat Nonlinear Systems

  • Joo, Jin-Man;Park, in-Bae;Park, Yoon-Ho
    • Transactions on Control, Automation and Systems Engineering
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    • 제3권1호
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    • pp.21-26
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    • 2001
  • In this study, we propose a two degree of freedom robust output tracking control method for a class of nonlinear system. We consider hyperbolically nonminimum phase single-input single-output uncertain nonlinear systems. We also consider the case that the nominal input-state equation is differentially flat. Nominal stable state trajectory is obtained in the flat output space via the flat output. Nominal feedforward control input is also computed from the nominal state trajectory. Due to the nature of the method, the generated flat output trajectory and control input are noncausal. Robust feedback control is designed to stabilize the systems around the nominal trajectory. A numerical example is given is given to demonstrate that robust tracking is achieved.

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