• 한국작물학회지
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• 제51권4호
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• pp.356-361
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• 2006

The present study was conducted to determine plant growth and physiological responses of corn, barnyardgrass, and soybean to ALA (5-aminolevulinic acid). ALA effect on early seedling growth of test plants was greatly concentration dependant, suggesting that it inhibits at higher concentrations. No significant difference in herbicidal activity of two types of ALA on plant height and weight of test plants was observed. Barnyardgrass was the most sensitive to ALA and followed by corn and soybean, indicating that both crop plants were less affected by ALA concentration as well as different growth stages than barnyardgrass. Greatly reduced chlorophyll contents from leaves of three plant species were observed with increasing of ALA concentration. Compared with untreated controls, higher amounts of three tetrapyrroles were detected from three crop plants, indicating more accumulation in ALA-treated plants. The differential selectivity among plant species would be explained with the differences in tetrapyrrole accumulating capabilities, the susceptibility of various greening groups of plant species to the accumulation of various tetrapyrroles, and their metabolism in various plant tissues. The results indicate that negative biological potential of ALA exhibited differently on plant species, and that the photodynamic herbicidal activity against susceptible plants highly correlated with the extent of tetrapyrrole accumulation by the species.

• 정보보호학회논문지
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• 제17권5호
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• pp.55-63
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• 2007

본 논문에서는 하드웨어 기반 블록 암호알고리즘에 대한 부채널분석 공격 취약성을 살펴보았다. 분석을 위해 ARIA 알고리즘을 FPGA에 구현하였으며 다양한 분석을 위해 두 가지 형태의 S-box로 나누어 구현하였다. 각각의 구현형태에 대해 DPA 공격, 근거리 DEMA 공격 및 원거리 DEMA 공격을 실험하였다. 기존에 발표된 소프트웨어 기반 스마트카드에 대한 DPA 공격결과와 비교했을 때 하드웨어(FPGA) 기반 암호알고리즘이 병렬처리 및 기타 이유로 인해 좀 더 많은 수의 수집신호가 필요하였지만 S-box의 구현형태에 상관없이 모든 부채널분석 공격에 취약함을 실험적으로 확인하였다.

• Genomics & Informatics
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• 제21권2호
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• pp.26.1-26.9
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• 2023

Stevens-Johnson syndrome (SJS) produces a severe hypersensitivity reaction caused by Herpes simplex virus or mycoplasma infection, vaccination, systemic disease, or other agents. Several studies have investigated the genetic susceptibility involved in SJS. To provide further genetic insights into the pathogenesis of SJS, this study prioritized high-impact, SJS-associated pathogenic variants through integrating bioinformatic and population genetic data. First, we identified SJS-associated single nucleotide polymorphisms from the genome-wide association studies catalog, followed by genome annotation with HaploReg and variant validation with Ensembl. Subsequently, expression quantitative trait locus (eQTL) from GTEx identified human genetic variants with differential gene expression across human tissues. Our results indicate that two variants, namely rs2074494 and rs5010528, which are encoded by the HLA-C (human leukocyte antigen C) gene, were found to be differentially expressed in skin. The allele frequencies for rs2074494 and rs5010528 also appear to significantly differ across continents. We highlight the utility of these population-specific HLA-C genetic variants for genetic association studies, and aid in early prognosis and disease treatment of SJS.

• 한국응용곤충학회지
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• 제55권1호
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• pp.17-26
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• 2016

기후변화는 국내 해충상의 변화에 영향을 주는 주요 요인 가운데 하나로 알려지고 있다. 특히 지구 온난화 모델에 따라 남방계 곤충의 서식지 확대가 예상되고 있다. 휴면 기작을 가지고 있지 않은 파밤나방(Spodoptera exigua)과 배추좀나방(Plutella xylostella)은 시설재배지를 중심으로 국내에서 월동이 가능한 것으로 알려지고 있다. 그러나 두 해충은 계절적 발생 양상에서 뚜렷한 차이를 보여주었다. 배추좀나방은 이른 봄철과 가을기간에 발생하고 여름 기간 중에는 발생하지 않았다. 반면에 파밤나방은 늦은 봄철에 나타나기 시작해 가을까지 지속적으로 발생하였다. 본 연구는 이러한 두 남방계 곤충이 계절적 발생 차이를 보이는 것이 이들이 갖는 고온에 대한 감수성 차이에 기인한 것으로 가정하였다. 이 가설을 증명하기 두 곤충의 내열성을 비교 분석하였다. 동일한 열처리($42^{\circ}C$)에서 배추좀나방 유충은 40 분 노출에 100% 사망률을 보인 반면, 파밤나방은 대부분의 유충이 80 분의 노출에서도 생존하였다. 이러한 내열성은 두 곤충 모두 이들의 발육시기에 따라 상이했다. 배추좀나방은 4령 유충과 성충이 가장 높은 내열성을 보인 반면, 파밤나방은 1령 유충에서 가장 높게 나타냈다. 두 곤충 모두는 $37^{\circ}C$에서 30 분간 전 처리 후 고온에 노출시키면 생존율이 뚜렷하게 증가했다. 이러한 내열성유기는 두 곤충 모두 혈림프의 글리세롤 함량 증가와 관련성을 보였다. 또한 파밤나방의 경우는 열충격단백질의 발현도 증가하였다. 따라서 이상의 결과는 여름기간 배추좀나방의 발생이 없는 것은 이 곤충의 고온에 대한 높은 감수성에 기인된 것으로 보이고, 반면에 파밤나방은 비교적 높은 내열성을 보유하여 여름 기간에도 발생을 지속시킨 것으로 해석되었다.

• 식물병연구
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• 제10권4호
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• pp.217-226
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• 2004

한 중 벼 도열병균의 특성 검정과 저항성원의 공동 평가를 통하여 병원균의 특성을 구명하고 주요 저항성원에 대한 정보와 한국 도열병균의 분화 현상이 중국으로부터 유래하였는지를 분석하였다. 각국의 대표균주 각각 100균주씩을 한국, 중국 판별품종 및 단인자 저항성 품종에 접종한 결과, 한국 병원균은 중국 단인자 저항성 품종에서 29개의 반응형을 보였으며, 한국균주 46%가 중국 NIL(LTH/일본품종 저항성 유전자)을 모두 침해하여, 우리나라 벼 육종 시 저항성원으로 적합지 않은 것으로 나타났다. 또한 한국판별품종에 대한 중국균주의 반응결과, KJ-201, KJ-301, KJ-403, KJ-105, KJ-101 레이스가 각각 11%, 10%, 9% , 8%, 7%의 비율로 나타났다. 그러나 RFLP-MGR586 profile은 한국 균주가 중국균주보다 band 수와 양상이 다양하여 변이가 심한 것으로 나타났으며, IRRI에서 육성한 11개의 단인자 저항성 품종에 대하여 한-중균주의 유전자 침해비율은 대체로 비슷한 경향이었다. Pi-z, Pi-3, Pi-5(t)는 한국 균주가 각각 56.6%, 58.1%, 45.4%침해하는 반면, 중국 균주는 각각 85.2%, 75.9%, 75.9%를 침해하여 중국 균주의 침해 비율이 높았고 Pi-b 유전자의 경우, 한국 균주의 82.6%가 침해하는 반면 중국 균주는 59.3%가 침해하여 한국 균주의 침해 비율이 높았다.

• 한국잡초학회지
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• 제4권1호
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• pp.96-106
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• 1984

Changes in weed floras and development of plant resistance to herbicides seemed to be closely related with increased and repeated use of herbicides. Herbicide use increased from 5% of the total consumption of pesticide in 1950 to 45% in 1976 in world basis. About 200 herbicides have been introduced to agriculture so as to control about 206 weed species which have been recorded important to human beings. In Korea, there was about 351 times in increased use of herbicides from 1966 to 1982. Interspecific selection by herbicide is mainly responsible for changes in weed floras and resulted in varying tolerance or susceptibility to herbicides, together with the changes of agricultural practices. The present trend toward continuous cereal cultivation throughout world will lead to type of changes in weed floras favorable to therophyte which can survive under unfavorable conditions as seeds rather than the types of geophyte which can survive unfavorable seasons as buds placed below soil surface. However, geophyte such as Sagitaria pygmaea, and Scirpus jurtcoides, and Cyperus rotundus and Cynodon dactylon in temperate warm climate become severe paddy weeds, presumably because of the removal of annual weeds by herbicides. Since differential tolerance to 2,4-D was firstly reported in Agrostis stolofera, about 30 species of weeds in 18 genera are presently known to have developed resistance to triazine herbicides. Resistance of weed biotypes to triazine herbicide is not mainly due to limited absorption and translocation or to the difference in metabolism, but is the result of biochemical changes at the site of metabolic activity, such as a loss of herbicide affinity for triazine binding site in the photosystem II complex of the chloroplast membrane. Genetical study showed that plastid resistance to triazine was wholly inherited through cytoplasmic DNA in the case of Brassica campestris. Plant tissue culture method can be utilized as an alternate mean of herbicide screening and development of resistance variants to herbicides as suggested by Chaleff and Parsons. In this purpose, one should be certain that the primary target process is operational in cell culture. Further, there are a variety of obstacles in doing this type of research, particularly development of resistance source and it's regeneration because cultured cells and whole plants represent different developmental state.

• Asian-Australasian Journal of Animal Sciences
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• 제22권3호
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• pp.336-342
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• 2009

Avian embryos at high altitude are independent of maternal protection against hypoxia, which is contrary to mammals. It is well known that chronic hypoxic exposure at key points can significantly impact on avian development. Tibetan Chicken, a Chinese indigenous breed, living in Tibetan areas with an altitude of 2.2 to 4.1 thousand meters, has an adaptive mechanism to hypoxia. In the present study, fertilized eggs of Tibetan Chicken were incubated under 13% and 21% oxygen concentration. Two lowland chicken breeds, Shouguang Chicken, an indigenous chicken breed in Shandong Province of China, and Dwarf Recessive White Chicken, an imported breed in Beijing, were used as control groups. The embryo mass and some organs such as brain, heart, liver, stomach and eye weight in the three species were measured at Hamburger-Hamilton stage 39, 41, 43 and 45 under hypoxic and normal conditions. The results showed that in hypoxia Tibetan Chicken significantly differed from the two lowland chicken breeds in embryo mass at Hamburger-Hamilton stage 41, 43 and 45 (p<0.01). In particular, Dwarf Recessive White Chicken and Shouguang Chicken showed retarded growth in hypoxic incubation (p<0.01), whereas Tibetan Chicken showed no significant difference between hypoxic and normal conditions (p>0.05). In addition, heart and the other organs showed different susceptibility to hypoxia at the studied stages. In conclusion, chronic hypoxia induced a change in the embryo development of the three different species and Tibetan Chicken showed adaptation to hypoxia. Of note, the embryo developmental physiology of Tibetan Chicken in response to hypoxia will shed light on the process of physiological acclimation or evolutionary adaptation as well as the study of clinical disease.

• Asian-Australasian Journal of Animal Sciences
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• 제25권2호
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• pp.278-285
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• 2012

Poultry products are an important source of Salmonella enterica. An effective way to reduce food poisoning due to Salmonella would be to breed chickens more resistant to infection. Unfortunately host responses to Salmonella are complex with many factors involved. To learn more about responses to Salmonella in young chickens of 2 wk old, a cDNA Microarray containing 13,319 probes was performed to compare gene expression profiles between two chicken groups under control and Salmonella infected conditions. Newly hatched chickens were orally infected with S. enterica serovar Enteritidis. Since the intestine is one of the important barriers the bacteria encounter after oral inoculation, intestine gene expression was investigated at 2 wk old. There were 588 differentially expressed genes detected, of which 276 were known genes, and of the total number 266 were up-regulated and 322 were down-regulated. Differences in gene expression between the two chicken groups were found in control as well as Salmonella infected conditions indicating a difference in the intestine development between the two chicken groups which might be linked to the difference in Salmonella susceptibility. The differential expressions of 4 genes were confirmed by quantitative real-time PCR and the results indicated that the expression changes of these genes were generally consistent with the results of GeneChips. The findings in this study have lead to the identification of novel genes and possible cellular pathways, which are host dependent.

• 전기학회논문지
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• 제64권9호
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• pp.1330-1336
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• 2015

It is necessary to study on acoustic and vibratory response of a MEMS resonant accelerometer before applying to military applications. In this paper, we analyze why the resonant accelerometer reacts to an acoustic wave and a high frequency vibration. And we describe experimental results on acoustic and vibratory response of the accelerometer. The accelerometer consists of a proof mass and a dual ended tuning fork. It is a differential resonant accelerometer with arranging a pair of accelerometers. The mode shape was analyzed to find out the input mode frequency by using a FEM simulation. Some experiments regarding the acoustic noise was carried out by using a tweeter and a microphone in the anechoic room. Results showed that the accelerometer reacted to the acoustic wave and vibration which had the input mode frequency as we had expected. We showed experimentally not only that the susceptibility of the accelerometer to an acoustic wave was 70 dB but also that the effectiveness of applying an acoustic absorber and a metal case was 20 dB, respectively. Also, we could minimize the vibratory response property of the accelerometer by installing a IMU with a silicone rubber mount pad.

• 대한조선학회논문집
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• 제55권1호
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• pp.9-21
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• 2018

Survivability of naval vessels is defined as the ability to perform functions and missions in a combat environment. Survivability has close relationship with the spatial layout of naval vessels. In order to maximize survivability, it must be considered from the early stage of design. However the existing concept of survivability was intended to be applied to unit vessels. So it was not suitable for assessment of spatial layout results at the early stage of design. In this paper, a simplified assessment method which can evaluate the spatial layout considering the survivability in the early stage of design has been proposed. For this, assessment layers were defined on survivability components such as susceptibility, vulnerability, and recoverability. Assessment layers of each component were overlapped to deduce a survivability layer of spatial layout alternatives. In addition, the proposed method and optimization algorithm were used to derive optimal spatial layout alternatives considering survivability.