• 제목/요약/키워드: Different sources

검색결과 3,409건 처리시간 0.037초

Mass-Based Metabolomic Analysis of Lactobacillus sakei and Its Growth Media at Different Growth Phases

  • Lee, Sang Bong;Rhee, Young Kyoung;Gu, Eun-Ji;Kim, Dong-Wook;Jang, Gwang-Ju;Song, Seong-Hwa;Lee, Jae-In;Kim, Bo-Min;Lee, Hyeon-Jeong;Hong, Hee-Do;Cho, Chang-Won;Kim, Hyun-Jin
    • Journal of Microbiology and Biotechnology
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    • 제27권5호
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    • pp.925-932
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    • 2017
  • Changes in the metabolite profiles of Lactobacillus sakei and its growth media, based on different culture times (0, 6, 12, and 24 h), were investigated using gas chromatography-mass spectrometry (MS) and liquid chromatography-MS with partial least squares discriminant analysis, in order to understand the growth characteristics of this organism. Cell and media samples of L. sakei were significantly separated on PLS-DA score plots. Cell and media metabolites, including sugars, amino acids, and organic acids, were identified as major metabolites contributing to the difference among samples. The alteration of cell and media metabolites during cell growth was strongly associated with energy production. Glucose, fructose, carnitine, tryptophan, and malic acid in the growth media were used as primary energy sources during the initial growth stage, but after the exhaustion of these energy sources, L. sakei could utilize other sources such as trehalose, citric acid, and lysine in the cell. The change in the levels of these energy sources was inversely similar to the energy production, especially ATP. Based on these identified metabolites, the metabolomic pathway associated with energy production through lactic acid fermentation was proposed. Although further studies are required, these results suggest that MS-based metabolomic analysis might be a useful tool for understanding the growth characteristics of L. sakei, the most important bacterium associated with meat and vegetable fermentation, during growth.

Reproductive Performance, Milk Composition, Blood Metabolites and Hormone Profiles of Lactating Sows Fed Diets with Different Cereal and Fat Sources

  • Park, M.S.;Shinde, P.L.;Yang, Y.X.;Kim, J.S.;Choi, J.Y.;Yun, K.;Kim, Y.W.;Lohakare, J.D.;Yang, B.K.;Lee, J.K.;Chae, Byung-Jo
    • Asian-Australasian Journal of Animal Sciences
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    • 제23권2호
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    • pp.226-233
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    • 2010
  • Different dietary cereal sources and fat types in the lactation diet were evaluated to investigate their effects on reproductive performance, milk composition, blood metabolites and hormones in multiparous sows. Twenty-four sows were randomly assigned to one of four treatments according to a 2${\times}$2 factorial arrangement of treatments. Each treatment had 6 replicates comprising 1 sow. Two cereal (corn or wheat) and two fat (tallow or soybean oil) sources were used to prepare iso-caloric and iso-nitrogenous diets. Sows fed corn-based diets lost less body weight (p = 0.003) and backfat thickness (p = 0.034), consumed more feed (p = 0.032) and had shorter wean-to-estrus interval (p = 0.016) than sows fed wheat-based diets. Fewer piglets and lower body weight of piglets (p<0.05) at weaning were noted in sows fed wheat-based diets than in sows fed corn-based diets. However, no significant effects (p>0.05) of dietary fat source and its interaction with dietary cereal source on sow body condition and reproductive performance were observed during lactation. Feeding of a corn-based diet improved (p<0.05) sow milk total solid, protein and fat, increased blood urea nitrogen (p = 0.032) and triglyceride (p = 0.018), and decreased blood creatinine (p = 0.011) concentration at weaning when compared with sows fed wheatbased diets. Sows fed corn-based diets had higher concentration of insulin (p = 0.048) and LH (p<0.05) at weaning than sows fed wheatbased diets. The results indicate that feeding corn-based diets to lactating sows improved sow body condition and reproductive performance compared with wheat-based diets regardless of fat sources.

위암환자에서 의무기록과 행정자료를 활용한 Charlson Comorbidity Index의 1년 이내 사망 및 재원일수 예측력 연구 (Prognostic Impact of Charlson Comorbidity Index Obtained from Medical Records and Claims Data on 1-year Mortality and Length of Stay in Gastric Cancer Patients)

  • 경민호;윤석준;안형식;황세민;서현주;김경훈;박형근
    • Journal of Preventive Medicine and Public Health
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    • 제42권2호
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    • pp.117-122
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    • 2009
  • Objectives : We tried to evaluate the agreement of the Charlson comorbidity index values(CCI) obtained from different sources(medical records and National Health Insurance claims data) for gastric cancer patients. We also attempted to assess the prognostic value of these data for predicting 1-year mortality and length of the hospital stay(length of stay). Methods : Medical records of 284 gastric cancer patients were reviewed, and their National Health Insurance claims data and death certificates were also investigated. To evaluate agreement, the kappa coefficient was tested. Multiple logistic regression analysis and multiple linear regression analysis were performed to evaluate and compare the prognostic power for predicting 1 year mortality and length of stay. Results : The CCI values for each comorbid condition obtained from 2 different data sources appeared to poorly agree(kappa: 0.00-0.59). It was appeared that the CCI values based on both sources were not valid prognostic indicators of 1-year mortality. Only medical record-based CCI was a valid prognostic indicator of length of stay, even after adjustment of covariables($\beta$ = 0.112, 95% CI = [0.017-1.267]). Conclusions : There was a discrepancy between the data sources with regard to the value of CCI both for the prognostic power and its direction. Therefore, assuming that medical records are the gold standard for the source for CCI measurement, claims data is not an appropriate source for determining the CCI, at least for gastric cancer.

국악기의 음향방사특성에 따른 국악당의 음향성능조사 (Investigation of the Acoustic Performance of Music Halls Using Measured Radiation Characteristics of the Korean Traditional Musical Instruments)

  • 한찬훈;이원구;정철호
    • 한국음향학회지
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    • 제24권8호
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    • pp.469-480
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    • 2005
  • 현재 국악기의 음향특성에 대한 상세 정보가 매우 부족하여 국악당의 설계에 있어서 최적의 음향을 전달하는 공간을 형성하지 못하게 하는 한 원인이 되고 있다. 따라서, 대중적이고 대표적인 국악기의 음향특성을 측정하고 분류한 후 데이터베이스를 구축하면, (1) 향후의 국악 및 국악기 개발에 대한 기초연구로서 활용될 수 있으며, (2) 국악 전용 연주장의 설계에 있어서 입력 데이터로 요긴하게 활용될 수 있으리라 판단된다. 본 연구는 국악기의 음향방사특성을 조사하기 위한 제2단계의 연구로서, 기존의 연구[1]에 새로운 국악기 8종을 추가하였다. 선정된 국악기는 현악기중에서 거문고와 해금, 관악기 중에서 피리와 태평소, 타악기 중 북과 꽹가리, 징 및 남성 창으로, 원거리 (far-field) 음향 방사특성을 조사하였다. 무향실에서 시행된 지향특성실험을 통하여 얻은 국악기의 음향특성을 컴퓨터 시뮬레이션을 적용하여 국악기의 지향특성의 차이를 규명하고 또한 다양한 형태의 공간에 음원의 방사특성의 차이에 따른 실내음향성능의 변이를 조사하였다. 측정 결과, 국악기마다 주파수별 지향특성은 각기 다르게 나타났으며 무지향성 음원과 국악 음원을 사용하였을 때 음향 인자들 사이에 큰 차이를 보였다. 본 연구에서 제시된 데이터와 설계 방법론 등은 향후 국악원의 설계에 있어서 기본적인 자료로 활용될 수 있다고 기대된다.

소규모 기업에 있어서 지식소싱 전략이 기업성과에 미치는 영향 고찰 (An Examination of Knowledge Sourcing Strategies Effects on Corporate Performance in Small Enterprises)

  • 최병구
    • Asia pacific journal of information systems
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    • 제18권4호
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    • pp.57-81
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    • 2008
  • Knowledge is an essential strategic weapon for sustaining competitive advantage and is the key determinant for organizational growth. When knowledge is shared and disseminated throughout the organization, it increases an organization's value by providing the ability to respond to new and unusual situations. The growing importance of knowledge as a critical resource has forced executives to pay attention to their organizational knowledge. Organizations are increasingly undertaking knowledge management initiatives and making significant investments. Knowledge sourcing is considered as the first important step in effective knowledge management. Most firms continue to make an effort to realize the benefits of knowledge management by using various knowledge sources effectively. Appropriate knowledge sourcing strategies enable organizations to create, acquire, and access knowledge in a timely manner by reducing search and transfer costs, which result in better firm performance. In response, the knowledge management literature has devoted substantial attention to the analysis of knowledge sourcing strategies. Many studies have categorized knowledge sourcing strategies into intemal- and external-oriented. Internal-oriented sourcing strategy attempts to increase firm performance by integrating knowledge within the boundary of the firm. On the contrary, external-oriented strategy attempts to bring knowledge in from outside sources via either acquisition or imitation, and then to transfer that knowledge across to the organization. However, the extant literature on knowledge sourcing strategies focuses primarily on large organizations. Although many studies have clearly highlighted major differences between large and small firms and the need to adopt different strategies for different firm sizes, scant attention has been given to analyzing how knowledge sourcing strategies affect firm performance in small firms and what are the differences between small and large firms in the patterns of knowledge sourcing strategies adoption. This study attempts to advance the current literature by examining the impact of knowledge sourcing strategies on small firm performance from a holistic perspective. By drawing on knowledge based theory from organization science and complementarity theory from the economics literature, this paper is motivated by the following questions: (1) what are the adoption patterns of different knowledge sourcing strategies in small firms (i,e., what sourcing strategies should be adopted and which sourcing strategies work well together in small firms)?; and (2) what are the performance implications of these adoption patterns? In order to answer the questions, this study developed three hypotheses. First hypothesis based on knowledge based theory is that internal-oriented knowledge sourcing is positively associated with small firm performance. Second hypothesis developed on the basis of knowledge based theory is that external-oriented knowledge sourcing is positively associated with small firm performance. The third one based on complementarity theory is that pursuing both internal- and external-oriented knowledge sourcing simultaneously is negatively or less positively associated with small firm performance. As a sampling frame, 700 firms were identified from the Annual Corporation Report in Korea. Survey questionnaires were mailed to owners or executives who were most erudite about the firm s knowledge sourcing strategies and performance. A total of 188 companies replied, yielding a response rate of 26.8%. Due to incomplete data, 12 responses were eliminated, leaving 176 responses for the final analysis. Since all independent variables were measured using continuous variables, supermodularity function was used to test the hypotheses based on the cross partial derivative of payoff function. The results indicated no significant impact of internal-oriented sourcing strategies while positive impact of external-oriented sourcing strategy on small firm performance. This intriguing result could be explained on the basis of various resource and capital constraints of small firms. Small firms typically have restricted financial and human resources. They do not have enough assets to always develop knowledge internally. Another possible explanation is competency traps or core rigidities. Building up a knowledge base based on internal knowledge creates core competences, but at the same time, excessive internal focused knowledge exploration leads to behaviors blind to other knowledge. Interestingly, this study found that Internal- and external-oriented knowledge sourcing strategies had a substitutive relationship, which was inconsistent with previous studies that suggested complementary relationship between them. This result might be explained using organizational identification theory. Internal organizational members may perceive external knowledge as a threat, and tend to ignore knowledge from external sources because they prefer to maintain their own knowledge, legitimacy, and homogeneous attitudes. Therefore, integrating knowledge from internal and external sources might not be effective, resulting in failure of improvements of firm performance. Another possible explanation is small firms resource and capital constraints and lack of management expertise and absorptive capacity. Although the integration of different knowledge sources is critical, high levels of knowledge sourcing in many areas are quite expensive and so are often unrealistic for small enterprises. This study provides several implications for research as well as practice. First this study extends the existing knowledge by examining the substitutability (and complementarity) of knowledge sourcing strategies. Most prior studies have tended to investigate the independent effects of these strategies on performance without considering their combined impacts. Furthermore, this study tests complementarity based on the productivity approach that has been considered as a definitive test method for complementarity. Second, this study sheds new light on knowledge management research by identifying the relationship between knowledge sourcing strategies and small firm performance. Most current literature has insisted complementary relationship between knowledge sourcing strategies on the basis of data from large firms. Contrary to the conventional wisdom, this study identifies substitutive relationship between knowledge sourcing strategies using data from small firms. Third, implications for practice highlight that managers of small firms should focus on knowledge sourcing from external-oriented strategies. Moreover, adoption of both sourcing strategies simultaneousiy impedes small firm performance.

HSPF를 이용한 농업비점오염원 최적관리방안에 따른 수질개선효과 예측 (Predicting the Effects of Agriculture Non-point Sources Best Management Practices (BMPs) on the Stream Water Quality using HSPF)

  • 이경석;이동훈;안영미;강주현
    • 한국습지학회지
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    • 제25권2호
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    • pp.99-110
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    • 2023
  • 농업지역에서 발생하는 비점오염물질은 타 지역에 비해 넓은 면적에서 배출되기 때문에 수질관리를 위해서는 발생원 제어와 배출수 관리와 같은 다양한 오염원 저감대책이 필요하며, 이를 위해서는 유역특성을 고려한 오염원별 배출량 및 최적관리방안에 따른 수질개선 효과를 정량적으로 파악할 필요가 있다. 이에 본 연구는 Hydrological Simulation Program-FORTRAN(HSPF)모델을 활용하여 유역내 오염원별 부하 및 주요 오염원저감방안에 대한 수질개선효과를 분석하여 농업지역의 비점오염관리대책 수립 지원을 목적으로 하였다. 연구지역은 경남 창녕군 계성천 유역으로 전체 면적대비 농업지역이 약 26.13%로 산림을 제외하고 지배적인 토지이용을 가지며, 주요 오염원은 농업활동에 기인하는 화학비료 및 액비살포와 축사에서 발생하여 야적 또는 농지에 살포되는 축분을 포함하고 있다. 계성천 유역에 대한 HSPF 모델 구축시 화학비료와 액비 사용량, 소규모 축사의 축분 발생량과 공공하수처리장, 분뇨처리장, 마을하수도 및 개인오수처리시설 등 점오염원 영향을 고려하였다. 특히 본 연구에서는 영양염류의 식생흡수, 침적, 흡탈착, 깊은침투에 의한 손실 등 상세 순환기작모의가 가능하도록 NITR 및 PHOS모듈을 활용하였다. 구축된 모델은 유역말단의 2015~2020년 측정값을 토대로 보·검정을 수행하였으며 모델이 유량 및 수질을 적절히 모의하는 것을 확인하였다. 오염저감시나리오는 농업비점관리(배수물꼬관리, 완효성비료와 사용), 축산비점관리(액비저감, 소규모 축사 축분관리), 생활계오염원제어(개인오수처리시설 관리) 등 세 부문으로 구분하고, 달성기간에 따라 단기, 중기, 및 장기로 구분하여 부문별로 단계별 저감대책을 구성하였다. 개별시나리오 모의 결과 수질개선에 효과는 완효성비료의 대체사용>배수물꼬관리>소규모축사 축분관리 순으로 나타났다. 유역 전반에 모든 관리방안을 적용하였을 때 장기적으로 TN, TP의 연간부하량은 각각 40.6%, 41.1%, 연평균 농도는 각각 35.1%, 29.2% 감소되는 효과를 보였다. 본 연구를 통하여 농업활동 우세 유역에서의 다양한 오염원 저감시나리오별 수질개선효과에 대한 예측 및 이에 기반한 오염관리대책 우선순위 도출을 위한 합리적인 방법론을 제시하고자 한다.

Microalgal Removal of $CO_2$from Flue Gases: Changes in Medium pH and Flue Gas Composition Do Not Appear to Affect the Photochemical Yield of Microalgal Cultures

  • Olaizola, Miguel
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제8권6호
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    • pp.360-367
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    • 2003
  • Our research objectives are to determine under what conditions microalgal-based $CO_2$capture from flue gases is economically attractive. Specifically, our objective here was to select microalgae that are temperature, pH and flue gas tolerant. Microalgae were grown under five different temperatures, three different pH and five different flue gas mixtures besides 100% $CO_2$(gas concentrations that the cells were exposed to ranged 5.7-100% $CO_2$, 0-3504ppm SO$_2$, 0-328ppm NO, and 0-126ppm NO$_2$). Our results indicate that the microalgal strains tested exhibit a substantial ability to withstand a wide range of temperature (54 strains tested), pH (20 strains tested) and flue gas composition (24 strains tested) likely to be encountered in cultures used for carbon sequestration from smoke stack gases. Our results indicate that microalgal photosynthesis is a limited but viable strategy for $CO_2$capture from flue gases produced by stationary combustion sources.

Edge Detection By Fusion Using Local Information of Edges

  • Vlachos, Ioannis K.;Sergiadis, George D.
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 2003년도 ISIS 2003
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    • pp.403-406
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    • 2003
  • This paper presents a robust algorithm for edge detection based on fuzzy fusion, using a novel local edge information measure based on Renyi's a-order entropy. The calculation of the proposed measure is carried out using a parametric classification scheme based on local statistics. By suitably tuning its parameters, the local edge information measure is capable of extracting different types of edges, while exhibiting high immunity to noise. The notions of fuzzy measures and the Choquet fuzzy integral are applied to combine the different sources of information obtained using the local edge information measure with different sets of parameters. The effectiveness and the robustness of the new method are demonstrated by applying our algorithm to various synthetic computer-generated and real-world images.

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청소년의 일상적 스트레스와 사회적 지지 지각의 관련성 연구 (A Study on the Perceives Stress and Social supports of Adolescent)

  • 이기숙;박소영
    • 대한가정학회지
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    • 제38권9호
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    • pp.93-106
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    • 2000
  • The Purpose of this study was to examine the adolescents'stress and social supports and the relationships of there two factors. Specifically, this study investigated the adolescents'stress and social supports depending on their sex, family status, socio-economic status. The subjects of this study were 467 middle school students in Pusan. Questionnaires were used consisting of adolescents'perceived stress and social supports for data analysis, Cronbach's $\alpha$-coefficient, frequency distribution, percentage, Oneway-ANOVA, t-test and Pearson's γ-coefficient were used. Major findings were as follows: Adolescents'stress were significantly different depending on their sex, father's educational level, family income and family intimacy The source of the adolescents'social support sources were different depending on their sex, family status, father's educational level, mother's educational level, family income and family intimacy. Adolescents'social support types were different depending on family status, lather educational level, mother educational level, father\`s job, family income and family intimacy. There were negative correlation between stress and social supports.

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Ontology Mapping and Rule-Based Inference for Learning Resource Integration

  • Jetinai, Kotchakorn;Arch-int, Ngamnij;Arch-int, Somjit
    • Journal of information and communication convergence engineering
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    • 제14권2호
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    • pp.97-105
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    • 2016
  • With the increasing demand for interoperability among existing learning resource systems in order to enable the sharing of learning resources, such resources need to be annotated with ontologies that use different metadata standards. These different ontologies must be reconciled through ontology mediation, so as to cope with information heterogeneity problems, such as semantic and structural conflicts. In this paper, we propose an ontology-mapping technique using Semantic Web Rule Language (SWRL) to generate semantic mapping rules that integrate learning resources from different systems and that cope with semantic and structural conflicts. Reasoning rules are defined to support a semantic search for heterogeneous learning resources, which are deduced by rule-based inference. Experimental results demonstrate that the proposed approach enables the integration of learning resources originating from multiple sources and helps users to search across heterogeneous learning resource systems.