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Standardization and HPTLC Fingerprinting of a Polyherbal Unani Formulation

  • Beg, Mirza Belal;Viquar, Uzma;Naikodi, Mohammad Abdul Rasheed;Suhail, Habiba;Kazmi, Munawwar Husain
    • CELLMED
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    • v.11 no.1
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    • pp.4.1-4.8
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    • 2021
  • Background: The Unani system of medicine has been practised since centuries for the treatment of a range of diseases. In spite of their efficacy they have been widely criticised due to the lack of standardization and poor quality control. Standardization of Unani medicine is a valuable issue at the present because they are very prone to contamination, deterioration, adulteration and variation in composition due to biodiversity as well as careless collection. Objective: To Standardize and Development of HPTLC Fingerprinting of a polyherbal Unani formulation Qurs-e-Safa. Materials and methods: The conventional and modern analytical techniques were used to standardise Qurs-e-Safa. The study was carried into three different batches of Qurs-e-Safa prepared with its ingredients. The parameters studied are organoleptic, microscopic, physicochemical parameters, phytochemical screening, TLC, HPTLC profile, aflatoxin, microbial load and heavy metal analysis. Results and conclusion: Qurṣ-e-Sa'fa is dark yellow in colour and aromatic smell. Uniformity of diameter and weight variation were found to be 13 ± 0, and 524.7 ± 1.72 mg. friability, hardness and disintegration time of all 3 batches were found to be (0.0615 ± 0.004, 0.0885 ± 0.0047 and 0.0725 ± 0.0058), (3.5 ± 0.2886, 3.67 ± 0.1674 and 3.67 ± 0.1674) and (16 to 17 minutes). Extractive value were found to be maximum in distilled water (38.488 ± 0.20, 37.3824 ± 0.38 and 39.8177 ± 0.13) followed by alcohol (27.5406 ± 0.54, 27.5656 ± 0.32 and 26.9229 ± 0.25). Loss of weight on drying, pH, total ash, acid insoluble ash, qualitative test was set in. Phytochemical screening revealed the presence of Carbohydrates, Phenols, Resins, Proteins, Steroids, fixed oil and Flavonoids. The microbial load was found absent and heavy metals were within permissible limits. The data evolved from the study may serve as a reference to validate and also help in the quality control of other finished products in future research.

Exploring the Epistemic Goals and Features of Biology-Related Knowledge Construction Activities Shaped by Pre-Service Elementary Teachers as Epistemic Agents (초등 예비교사가 인식적 행위주체로서 고안한 생명과학 관련 지식 구성 활동의 인식적 목표 및 특성 탐색)

  • Ha, Heesoo
    • Journal of The Korean Association For Science Education
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    • v.41 no.1
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    • pp.47-57
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    • 2021
  • This study aims to explore the epistemic goals that pre-service elementary teachers can construct in their biology-related knowledge construction activities, how these goals are constructed, and how the shaping of the knowledge construction activities around the goals was afforded or constrained. The research participants were 26 pre-service teachers, divided into 11 groups of two or three to engage in the activity. Their discussions and products were collected and used as data for this study. The analysis revealed that the teachers constructed three types of epistemic goals: making sense of natural phenomena, proposing the most effective course of action, and proposing solutions to problems based on their causes. Construction of different types of goals depended on the conclusions the pre-service teachers expected to draw based on the explored natural phenomena. It was found that the elicitation of the pre-service teachers' epistemic goals could facilitate their shaping of the knowledge construction activity as an evidence-based justification. The participants planned the construction of mechanistic explanations of natural phenomena with the epistemic goals of 'making sense of natural phenomena' or 'proposing solutions to problems based on their causes.' However, enacting their knowledge construction plans with sophisticated epistemic features was constrained due to the limited resources available. This study can contribute to developing instructional strategies that facilitate learners' epistemic agency and addressing epistemic agency in the development of pre-service teacher education methods.

Physicochemical properties of the materials used for the production of celadon maebyeong inlaid with cloud-and-crane designs and changes in their morphological properties by production stage (청자상감운학문매병 제작 재료의 물리화학적 특성 및 제작 단계별 형상학적 특성 변화)

  • Kim, Jihye;Ha, Jihyang;Han, Minsu
    • Conservation Science in Museum
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    • v.25
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    • pp.63-84
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    • 2021
  • In order to investigate the diverse physicochemical changes that occurred in traditional Korean pottery during its production, including before and after firing, this study produced six replicas of a celadon maebyeong inlaid with cloud-and-crane designs, respectively corresponding to the process of shaping, carving, inlaying designs, first firing, glazing and second firing, respectively. It then conducted a scientific study of these six replicas and analyzed their images through high-resolution three-dimensional transmission imaging. The materials used for the replicas show different mineral phases and even colors depending on the components of each material. For example, black inlay with a high content of iron oxide (Fe2O3) shows dark colors and white inlay with a high alumina (Al2O3) content appears white. Physicochemical properties such as chromaticity and magnetic susceptibility and major components of the replicas were confirmed by the differences in the density in the computed tomography (CT) images. The characteristics of fired products such as fine structure, absorption ratio, apparent porosity, and other characteristics of the major mineral components were identified by the presence of pores and the formation of cracks inside the replicas in the image analysis.

Development of ITS sequence based SCAR marker and multiplex-SCAR assay for the rapid authentication of Tetrapanacis Medulla and Akebiae Caulis (통초(通草), 목통(木通) 신속 감별용 ITS 염기서열 기반 SCAR 마커 및 Multiplex-SCAR 분석법 개발)

  • Noh, Pureum;Kim, Wook Jin;Park, Inkyu;Yang, Sungyu;Choi, Goya;Moon, Byeong Cheol
    • The Korea Journal of Herbology
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    • v.36 no.1
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    • pp.9-17
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    • 2021
  • Objectives : Tetrapanacis Medulla and Akebiae Caulis are one of the most frequently adulterated herbal medicines because of their confusability of terms in the ancient writings and the similarity of morphological features of dried herbal products. The major adulterant is Aristolochia manshuriensis (Guanmutong) which has a serious safety concern with its toxicity. To ensure the safety and quality of the two herbal medicines, it is necessary to discriminate the toxic adulterant from authentic species. The aim of this study is to develop SCAR markers and to establish the multiplex-SCAR assay for discrimination of four plant species related to Tetrapanacis Medulla and Akebiae Caulis. Methods : ITS regions of fifteen samples of four species (Tetrapanax papyrifer, Fatsia japonica, Aristolochia manshuriensis, and Akebia quinata) collected from different sites were amplified and sequenced. Fifteen obtained ITS sequences were aligned and analysed for the detection of species-specific sequence variations. The SCAR markers were designed based on the sequence alignments and then, multiplex-SCAR assay enhancing rapidity was optimized. Results : ITS sequences clearly distinguished the four species at the species level. The developed SCAR markers and multiplex-SCAR assay were successfully discriminated four species and detected the adulteration of commercial product samples by comparison of the amplified DNA fragment sizes. Conclusions : These SCAR markers and multiplex-SCAR assay are a rapid, simple, and reliable method to identify the authentic Tetrapanacis Medulla and Akebiae Caulis from adulterants. These genetic tools will be useful to ensure the safety and to standardize the quality of the two herbal medicines.

Estimation of soil moisture based on Sentinel-1 SAR data: Assessment of soil moisture estimation in different vegetation condition (Sentinel-1 SAR 토양수분 산정 연구: 식생에 따른 토양수분 모의평가)

  • Cho, Seongkeun;Jeong, Jaehwan;Lee, Seulchan;Choi, Minha
    • Journal of Korea Water Resources Association
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    • v.54 no.2
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    • pp.81-91
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    • 2021
  • Synthetic Apreture Radar (SAR) is attracting attentions with its possibility of producing high resolution data that can be used for soil moisture estimation. High resolution soil moisture data enables more specific observation of soil moisture than existing soil moisture products from other satellites. It can also be used for studies of wildfire, landslide, and flood. The SAR based soil moisture estimation should be conducted considering vegetation, which affects backscattering signals from the SAR sensor. In this study, a SAR based soil moisture estimation at regions covered with various vegetation types on the middle area of Korea (Cropland, Grassland, Forest) is conducted. The representative backscattering model, Water Cloud Model (WCM) is used for soil moisture estimation over vegetated areas. Radar Vegetation Index (RVI) and in-situ soil moisture data are used as input factors for the model. Total 6 study areas are selected for 3 vegetation types according to land cover classification with 2 sites per each vegetation type. Soil moisture evaluation result shows that the accuracy of each site stands out in the order of grassland, forest, and cropland. Forested area shows correlation coefficient value higher than 0.5 even with the most dense vegetation, while cropland shows correlation coefficient value lower than 0.3. The proper vegetation and soil moisture conditions for SAR based soil moisture estimation are suggested through the results of the study. Future study, which utilizes additional ancillary vegetation data (vegetation height, vegetation type) is thought to be necessary.

A study on the comparative test of chemical and thermal properties of virgin and recycled PET products (버진 및 리사이클 PET 제품의 화학적·열적 특성 비교시험에 관한 연구)

  • Kim, Kyoung Pil;Seo, Kyung Jin;Park, Soo-Yong;Chung, Ildoo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.33-39
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    • 2021
  • As the interest and demand in the recycled yarn field has increased rapidly worldwide, domestic companies are also promoting research and development and business on recycled yarn. The chemical and thermal properties of four types of virgin and recycled PET samples from A and B company, which are the leading domestic companies in the recycled polyester yarn business, were confirmed through infrared (FT-IR) spectroscopy and differential scanning calorimetry (DSC). Virgin and recycled PET from two companies were compared. FT-IR spectroscopy revealed the typical spectra of PET for both companies and a different peak at 872 cm-1. DSC confirmed that the melting point and crystallization temperature of recycled PET were lower than those of virgin PET. These results indicate that small amounts of contaminants are an important parameter affecting the thermal properties of recycled PET. In the DSC results after seven repeats of the heating and cooling processes, all four samples showed that a lower melting point, crystallization temperature, and low heat flow intensity increased with increasing number of cycles. The results of melting and crystallization enthalpy also showed similar patterns.

A Study on the Influence of Sentiment and Emotion on Review Helpfulness through Online Reviews of Restaurants (레스토랑의 온라인 리뷰를 통해 감성과 감정이 리뷰 유용성에 미치는 영향에 관한 연구)

  • Yao, Ziyan;Park, Jiyoung;Hong, Taeho
    • Knowledge Management Research
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    • v.22 no.1
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    • pp.243-267
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    • 2021
  • Sentiment represents one's own state through the process of change to stimulus, and emotion represents a simple psychological state felt for a certain phenomenon. These two terms tend to be used interchangeably, but their meaning and usage are different. In this study, we try to find out how it affects the helpfulness of reviews by classifying sentiment and emotion through online reviews written by online consumers after purchasing and using various products and services. Recently, online reviews have become a very important factor for businesses and consumers. Helpful reviews play a key role in the decision-making process of potential customers and can be assessed through review helpfulness. The helpfulness of reviews is becoming increasingly important in practice as it is utilized in marketing strategies in business as well as in purchasing decision-making issues of consumers. And academically, the importance of research to find the factors influencing the helpfulness of reviews is growing. In this study, Yelp.com secured reviews on restaurants and conducted a study on how the sentiment and emotion of online reviews affect the helpfulness of reviews. Based on the prior research, a research model including sentiment and emotions for online reviews was built, and text mining analyzes how the sentiment and emotion of online reviews affect the helpfulness of online reviews, and the difference in the effects on emotions It was verified. The results showed that negative sentiment and emotion had a greater effect on review helpfulness, which was consistent with the negative bias theory.

Development of Smart Athleisure Fashion for Dumbbell Economy -Focused on the Analysis of Upper and Lower body muscle strength by angle- (덤벨 이코노미 현상을 반영한 스마트 애슬레저 패션 개발 -상·하체의 각도별 근력운동을 중심으로-)

  • Kim, Ga-Yeon;Kim, Youn-Hee
    • Journal of the Korea Convergence Society
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    • v.12 no.3
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    • pp.165-176
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    • 2021
  • Recently, interest in home training and changes in lifestyle are expanding the market in the healthcare field, and high value-added fashion products reflecting the dumbbell economy phenomenon are being released. This study had the following objectives: to investigate the possibility of developing a fashion item that can be applied to the dumbbell economy phenomenon; to develop the UI/UX of a smartphone application for beginners who wish to work out their upper and lower bodies regardless of time and space; and to create a wearable customized smart athleisure fashion device. First, the study identified factors related to exercise methods, breathing techniques, and range of exercises for beginners by investigating the postures of workouts of the upper and lower bodies by angles. Based on the results, the study collected empirical data through a user needs analysis from muscle strengthening exercise experts to verify the significance of the study and use as fundamental data. Second, the study developed the UI/UX of a smartphone application with three different contents: counting, suggesting exercise postures, and providing exercise calendars. Further, the study analyzed necessary user-centered concepts and characteristics in terms of design and technology and developed a wearable customized smart athleisure fashion device based on the results.

Development and Effectiveness Evaluation of Acupressure Bed with Variable Type Bogie (변동형 대차 구동방식의 지압 침대 개발 및 유효성 평가)

  • Heo, Sung-Phil;Park, Se-Jin;Ahn, Do-Hyun
    • Journal of Korea Society of Industrial Information Systems
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    • v.25 no.6
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    • pp.47-54
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    • 2020
  • The acupressure is a treatment that applies pressure to certain parts of the body and has been mainly used for pain relief in the field of oriental medicine. However, the treatment effect is often different depending on the practitioner's ability, experience, and physical strength, so standardized acupressure is needed. In this regard, the equipment is being released, but this is mainly a rolling massage method, which reduces energy concentration and poses a risk of injury. Therefore, in this study, a device that provides vertical acupressure based on variable bogie (wheel truck) was implemented. As a result of experimenting with load and body pressure distribution and desirability to validate the device's bearing pressure, the acupressure rod held up to 150kg, the body pressure ratio was measured lower than the body pressure ratio of the comparison item in section 0%

Design and Implementation of Modbus Communications for Smart Factory PLC Data Collection (스마트팩토리 PLC 데이터 수집을 위한 Modbus 통신 설계 및 구현)

  • Han, Jin-Seok;Yoo, Jae-Soo
    • The Journal of the Korea Contents Association
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    • v.21 no.4
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    • pp.77-87
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    • 2021
  • Smart Factory refers to a factory that can be controlled by itself with an intelligent factory that improves productivity, quality and customer satisfaction by combining the entire process of manufacturing and production with digital automation solutions. The manufacturing industry around the world is rapidly changing, with Germany, Europe, and the United States at the center. In order to cope with such changes, the Korean government is also implementing a policy to spread the supply of smart factories for small and medium-sized companies, and related ministries and agencies such as the Ministry of Commerce, Industry and Energy, the Ministry of SMEs and Venture Business, the Korea Institute of Technology and Information Promotion, and local technoparks, as well as large companies such as Samsung, SK and LG are actively investing in smart manufacturing projects to support smart factories[1]. Factory Automation (FA) construction has many issues regarding the connection of heterogeneous equipment. The most difficult aspect of configuring various communications from various equipment is the reason. Although it may not be known if there are standards or products made up of the same company, it is not easy to build equipment that is old, up-to-date, and different use environments through a series of communications. To solve this problem, we would like to propose a method of communication using Modbus, one of FieldBus, which is one of the many industrial devices of PLC, a representative facility control system, and is used as a communication standard.