• 대한지역사회영양학회지
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• 제16권6호
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• pp.627-635
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• 2011

The prevalence of Atopic Dermatitis (AD), a non-infective chronic inflammatory skin disease, is increasing worldwide. Avoiding the allergen is the basic principle in the treatment of AD. However, when the allergen is food, excessive restriction can lead to nutrition deficiency. The objective of the study was to examine the status of the dietary restriction and compare the caregiver's restriction practice with doctor's recommendation in Korean children with AD. A total of 158 children diagnosed with Atopic Dermatitis were recruited for this study. Information about foods that aggravate AD symptoms and food restriction were collected from the mothers of 158 children aged 6 month-5 year with AD using questionnaires. Food restriction recommendation by doctor was collected through medical chart. McNemar and Margianl homogeneity tests were used to detect a relationship between food restriction recommended by doctor and current practice by mother. There were significant proportion differences of food restriction for each food between by doctor and mother. We found 75.9% of children were avoiding eggs although only 61.4% were recommended for egg restriction by a doctor. Children with restriction of more than 4 kinds of food were 53.2% compared to 13.3% by doctor. Excessive restrictors tended to be younger and diagnosed at younger age. The caregivers of excessive restrictors had trends of "being older" and "having higher income". Avoidance of common foods in children without food allergy could result in malnutrition or impaired growth. Nutrition education is needed for sound practice and nutrition care in children with Atopic Dermatitis as well as interactive communication between caregivers and experts.

• The Korean Journal of Physiology
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• 제10권2호
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• pp.23-28
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• 1976

Author have already reported that urinary aldosterone excretion of the Korean who usually eat high sodium diet is significantly lower comparing with the American, although the plasma aldosterone concentration is identical in the former with that of the latter. Measurement of urinary aldosterone excretion and Plasma concentration only is insufficient to establish the pressence and/or mode of evolution of the Korean. In this experiments, aldosterone secretion rate(ASR) was measured in normotensive Korean during high and low dietary sodium intake with or without additional potassium supply. Results were as follows; 1) In normal Korean, dietary sodium restriction resulted in appreciable increase in ASR, and a sustained increase in urinary aldosterone excretion with an increase in plasma level. 2) Oral potassium loading easily stimulated the adrenal cortex of the Korean who already adapted to a high sodium diet when dietary sodium is still identical with not·mal American. 3) Quantitative relationships between aldosterone secretion rate, plasma concentration and urinary excretion of aldosterone were altered by potassium loading. 4) Urinary aldosterone excretion didn't reflect concurrent increase aldosterone secretion in subjects with Potassium intake. It was discussed that the changes of tile relationships and of adrenal hyper response on Potassium Beading in the Korean will be elucidated by measuring the metabolic clearance rate.

• 현장농수산연구지
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• 제18권1호
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• pp.13-24
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• 2016

본 연구는 비타민 A와 D의 공급제한이 거세 한우의 육질등급에 미치는 영향을 조사하기 위해 수행하였다. 비육전기(15개월령) 거세 한우 60두를 총 4개의 처리구[대조구(C), 비타민 A 제한구(-A), 비타민 D 제한구(-D)와 비타민 A 및 D 제한구(-AD)]에 15두씩 배치하여, 15개월령부터 23개월령까지 총 8개월 동안 처리구에 따라 비타민 A 및 D를 첨가하지 않는 방법으로 비타민 공급을 제한하였다. 이후 24개월령부터 26개월령까지는 비타민 A 및 D를 사료 원물의 0.05% 첨가, 27개월령부터 출하까지는 0.1% 첨가하여 비타민 A 및 D 공급이 제한되지 않도록 하였다. 본 연구의 결과를 종합하면, 15개월령 거세 한우에게 비타민 A와 D의 공급을 8개월동안 제한시킨 결과 1일 건물 섭취량에는 영향을 미치지 않았고 또한 체중, 일당증체량 및 사료 요구율에도 영향을 미치지 않았다. 그러나 혈중 retinol 농도는 비타민 A의 공급 제한에 의해 최대 약 50% 정도까지 감소하였다. 또한 혈중 25(OH)D3 농도는 비타민 D의 공급제한에 의하여 최대 약 55% 정도까지 감소하였다. 거세 한우의 비타민 A 및 D 공급 제한은 도체중, 등지방두께, 배최장근 단면적, 육량지수 및 육량등급에 영항을 미치지 않은 것으로 나타났다. 반면 비타민 A의 공급 제한은 마블링지수를 17% 정도 유의적으로 향상시켰다. 비타민 D의 공급 제한은 마블링 지수를 유의적으로 증가시키지는 않았지만 수치적으로(약 5%) 증가시키는 경향을 보였다. 결론적으로 본 연구결과는 거세 한우의 근내지방 침착 향상을 위해서는 비타민 A의 공급제한 방법이 비타민 D 공급제한 보다 효율적임을 제시하였고 한우에서도 일본의 화우와 마찬가지로 비육전기에 비타민 A를 제한 할 경우 근내지방도 향상을 통해 고급육생산이 가능함을 제시하였다.

• 한국식품영양과학회지
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• 제30권3호
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• pp.521-527
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• 2001

The effects of dietary restriction (DR) on antioxidant enzymes were studied in liver, lung and erythrocytes of diabetic rats. Experimental animals used Sprague-Dawley (SD; body weight 350$\pm$20g) male rats and Otsuka Long Evans Tokushima fatty (OLETE; body weight 5--$\pm$30g) male rats, as a model of type 2 diabetes mellitus. Type I diabetes was induced in SD rats by intramuscular injection of alloxan (80 mg/kg BW). Animals were randomly assigned either to continue the ad libitum diet or 40% DR (60% intake of ad libitum diet) groups. The body weight was measured at every 2 weeks to 4 months following DR. The activities of antioxidant enzymes (superoxide dismutase (SOD), catalase, glutathione peroxidase (GSHPx) were measured in liver, lung and erythrocytes and the concentration of TBARS as a marker of reactive oxygen species-induced tissue injry was also measured in rats after 4 months 40% DR. The body weight 4 months after 40% DR of control SD, alloxian-diabetid SD and OLETE rats were 80%, 98% and 75% of each control groups, respectively. The activities of SOD, catalase and GSHPx in lung and erythrocytes of rats were not change by 40% DR but in 4 month 40% DR rat liver, the activities of SOD and catalase were increased in control SD, alloxan-diabetic SD, and OLETF groups. The concentration of TBARS in lung and erythrocytes was also not changed by 40% DR, while liver TBARS concentration was decreased in OLETF and control SD rats compared to each non-DR control rats. These results suggested that the body weight changes in diabetic rats by DR was more prominent in type 2 diabetes and changes of antioxidant enzymes is most prominent in liver by DR either type 1 and 2 diabetic rats.

• 동아시아식생활학회지
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• 제24권3호
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• pp.291-300
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• 2014

This study determined the effects of television (TV) advertising restriction of Energy-Dense and Nutrient-Poor Foods on product and promotion activities by food companies producing or selling children's favorite foods. A survey using a selfadministered questionnaire was conducted via on-line or fax by marketers or R&D managers from 108 food companies. The data from 55 respondents (50.9%) were analyzed. Restriction exerted positive effects on food products with respect to compliance with labeling requirements (4.0 out of 5 points) and reinforcement of nutritional contents examination of new products (3.7 out of 5 points). Reformulations of products such as reduction of nutrients like sodium, sugar and fat were also reported. In addition, food companies underwent diverse changes in promotional activities, including modification of package designs and displays in stores, offering free gifts, discounts, etc. In conclusion, restriction of TV food advertising may contribute to improvement of children's food environment by encouraging food companies to make favorable product changes. On the other hand, the results also revealed that food companies adopt diverse marketing channels that are not yet under regulation. Hence, to make policies more effective, regulation needs to be extended from TV to other marketing channels to which children are easily exposed.

• 대한영양사협회학술지
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• 제24권4호
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• pp.344-360
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• 2018

This study examined the sociodemographic factors, health-related habits, chronic diseases, dietary habits, and nutrient intake according to the self-rated health status in a group aged over 65 years by analyzing the nationally representative Korean survey data. A total of 1,510 subjects were analyzed among the participants of the 2016 Korean National Health and Examination Survey (KNHANES). Statistical analyses for complex samples were performed using the SPSS software package (version 19.0) The study subjects were divided into two groups (healthy group vs. unhealthy group) based on their self-rated health status. The percentage of the healthy group was 66.5%. Gender, age, education level, household income, job (P<0.001, respectively), marital status, and basic living allowance (P<0.05, respectively) were significant sociodemographic variables of the self-rated health status. Alcohol consumption (P<0.01), aerobic physical activity, stress, quality of life, not feeling very well, depression and activity restriction (P<0.001, respectively) were also significant health-related variables of the self-rated health status. Blood glucose, anemia (P<0.05, respectively), and chewing problems (P<0.001) were significant chronic disease-related variables of the self-rated health status. Adequate intakes of protein, dietary fiber, phosphorus, thiamin, niacin, vitamin C (P<0.001, respectively), calcium, sodium, potassium (P<0.01, respectively), iron, vitamin A, and riboflavin (P<0.05, respectively) were also significant variables of the self-rated health status. In complex samples multiple logistic regression analysis, the self-rated health status was influenced significantly by the aerobic physical activity (P<0.01), stress level (P<0.05), depression (P<0.001), quality of life (P<0.001), not feeling very well (P<0.001), activity restriction (P<0.001), chewing problem (P<0.05), and adequate intake of iron (P<0.05). These results suggest that activity restriction, mental health, adequate iron intake, and physical activity may be associated with the self-rated health status in the elderly.

• Toxicological Research
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• 제6권2호
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• pp.167-182
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• 1990

Dietary restriction (caloric restriction) is the only intervention which has been reliably shown to extend the maximum life span of warm-blooded animals and delay the many phenomena associated with aging. It is also one of the most effective modulators of toxicity, especially cancer endpoints. In spite of the known modulator effects of caloric restriction, the biological mechanisms responsible for these effects had not been in vestigated until recently. The National Center for Toxicological Research (NCTR), in a collaborative effort with the National Institute of Aging (NIA), initiated a project whereby nine (9) combinations of rodent species/strains and diets were fed both restricted and ad libitum. The NIA's initiative was to identify biomarkers of aging whereas NCTR's initiative was to identify the biological effects associated with the profound effects caloric restriction has in protecting against both spontaneous (age-related) and chemically-induced toxic endpoints. Independent of sex or species, caloric restriction has similar effects on body temperature, oxygen consumption and $CO_2$production. Caloric restriction also decreased lipid glycolysis and metabolism in rats and mice, which suggest decreased production of metabolites which could lead to fatty acid epoxide formation. The age-associated loss of ciradian regulation of intermediate enzymes is also significantly reduced. Moreover, caloric restriction reduced the age-associated feminization of sexually dimorphic liver isozymes, increased several glucocorticoid responsive isozymes, elevated glucagon/insulin ratios, produced less microsomal superoxide and enhanced the capacity for utilzing detoxicating metabolic pathways. Calorically restricted rats have less than half the number of aflatoxin ($AFB_1$)-DNA adducts than ad libitum animals and urinary excretion of $AFB_1$ was increased significantly. Finally, DNA repair mechanisms are enhanced and oncogene expression is decreased in calorically restricted animals.

• 한방비만학회지
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• 제2권1호
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• pp.83-87
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• 2002

Increasing body weight is closely associated with increasing risk for glucose intolerance and type II diabetes. Especially, abdominal distribution of weight and visceral obesity also seriously increase the morbidity and mortality. Dietary program including very-low-calorie diet(VLCD) is regarded as most effective in the control of obesity and diabetes, which mainly due to calorie restriction rather than weight loss itself. We are reporting a case of diabetes with obesity whose fast glucose was over 220 mg/dl and BMI was $25.1kg/m^2$(fat rate 32.8%, WHR 0.9). She was prescribed VLCD and oriental medical diet program. After 10 days of hospitalization, her glucose level dropped dramatically with 3kg loss of body weight She has further lost her weight until about 53kg, but the glucose level ceased to go down probably due to loosened calorie restriction.

• Journal of Nutrition and Health
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• 제18권1호
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• pp.23-28
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• 1985

분만전후 Sprague Darwley 암컷 쥐에서 양적으로 식이를 계한하여 임의로 먹인 Control group의 일일평균섭취량이 1/2의 시중사료를 식이제한 group에게 주었다. Control group은 실험기간 동안 임의로 먹게 두었고, Deficient I group은 임신중에는 임의로 먹였고 분만후부터 이유시까지는 1일 20g의 사료를 주었다. Deficient II group은 임신 15일부터 분만시까지 1일 15g의 사료를 주었고 분만후부터 이유시까지는 1일 20g의 사료를 주었다. 각 group에서 새끼쥐가 출생한 날을 0일로 해서, 0, 3, 7, 10, 14, 21일에 새끼쥐의 serotonin, ca-techolamine 및 tryosine의 함량을 측정했다. 새끼쥐 뇌의serotonin함량은 control group에 비해 식이제한 group에서 출생 7일부터 유의적으로 낮아졌으며, 두 식이제한 group사이에서는 출생 14일과 21일에 유의적인 차를 보였다. 뇌에서 norepinephrine과 dopamine같은 catecholamine은 Control group보다 식이제한 group에서 유의적으로 낮았지만, 두 식이제한 group사이에서는 유의적 차를 보이지 않았다. Catecholamine의 전구체인 tyrosine은 식이제한 group의 뇌에서보다 Control group에서 출생 3일에 유의적으로 낮았으며, 출생 14일에는 Deficient I group의 tyrosine함량이 Control group과 Deficient II group의 뇌에서 보다 유의적으로 낮았다. 임신 마지막 주와 수유시의 어미쥐의 식이제한은 새끼쥐 뇌에서 정상적인 catecholamine합성을 지연시켜 주는 것으로 추측되며, 만일 식이제한을 시키는 기간을 이유 후로 연장시켜 주면, 뇌에서 유의적으로 낮은 catecholamine의 함량이 정상으로 회복될 수 있으리라 기대된다. 본 연구결과를 통하여 볼 때, 분란전후의 어미쥐에게 영양부족을 시키면, 새끼쥐 뇌성장발육과 조성이 정상적으로 될 수 없음을 알 수 있다.

• Journal of Nutrition and Health
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• 제24권3호
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• pp.149-156
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• 1991

고지방식이와 총열량섭취 제한식이가 protein kinase C 활성에 미치는 영향을 규명하고자 기타 양양소 또 총열량섭취가 정확이 조절된 식이를 제조하여 투여해본 결과, protein kinase C의 활성은 본 실험에서 사용한 옥수수유의 양의 증가에 따라 cytosolic과 membrane-associated protein kinase C의 활성을 모두 증가시키는 것을 관찰 하였다. 또한 기타 영양소는 같게 투여하고 열량소만 40% 감소시킨 실험군은 대조군에 비해 양쪽의 protein kinase C가 모두 감소하는 경향을 보였다.