• Journal of Nutrition and Health
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• v.30 no.7
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• pp.825-831
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• 1997

This study was to investigate the effect on weight control and changes in serum glucose, total protein , GPT, GOT , cholesterol, triglyceride, calcium, and phosphorus contents of seventeen overweight female college students during experimental periods [before grape diet(0 day-, after grape diet (3 day), after control diet(3 day), after normal diet(30 day)]. The mean weight, height , BMI, and Rohrer index of the subjects at the onset of the study was 58.91$\pm$5.22kg, 159.94$\pm$6.01cm, 22.96$\pm$1.17, and 20.06$\pm$1.48 respectively. During the study subjects, conducted grape diets, control diets, and normal diets to control their weight. They analyzed their changes in anthrophometric variables. The mean weight was significantly decreased from 58.29$\pm$7.85kg to 57.2$\pm$8.23kg after normal diet(p<0.05). Therefore BMI (body mass index) and Rohrer index was also significantly decreased after experimental periods. The analysis of dietary intake showed that the grape diet induced unbalanced low nutrient intake, but the intake of total calories and other nutrients were almost recovered their onset of the study during control and normal diets. The concentration of serum glucose, cholesterol, triglyceride GOT, and GTP were significantly(p<0.05) decreased and significantly(p<0.05) increased again during experimental periods. Calcium concentrations were not affected by grape diet, but phosphorus concentration was significantly reduced after grape and control diet.

• Journal of Nutrition and Health
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• v.7 no.2
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• pp.37-51
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• 1974

This Study was carried out to observe the effect of nutritional condition on the change of protein metabolism in the animal body by feeding on imbalanced protein diet. A total 242 growing male albino rats, weighing $115{\sim}120$ gm, were used for the experimental animals. The rats were fed on the standard diet(st), protein flee diet(pf) and imbalanced protein diet(ib) for twelve weeks respectively. Hemoglobin, packed cell volume in blood, and total nitrogen, amino acid nitrogen, urea-nitrogen, creatinine, transaminases(GPT, GOT) in liver and serum, and total nitrogen in small intestine, and total nitrogen, urea-nitrogen In small intestine, and total nitrogen, urea-nitrogen, creatinine, urea-nitrogen/creatinine ratio in urine were measured. The results obtained are as follows; 1. The gained body weight were lower in pf group and ib group than those of st group. The gained body weight fed for 12 weeks, were 80% lower in pf group than those of st group, and the body weight of pf group for $50{\sim}75$ days feeding were $40{\sim}60%$ decreased, compared with the stating weight, and then all of them died. 2. The change of the brain, liver, kidney, spleen and small intestine by feeding on imbalanced diet for 12 weeks were no remarkable difference with the starting weight, but those of protein free diet group were half or more decrease and those were significantly lower in spleen and small intestine especially than the other organ 3. The contents of hemoglobin in pf group for 8 weeks feeding, and the packed cell volume in pf group for 8 weeks feeding and in ib group for 12 weeks feeding were decreased. but those of the other feeding group were almost same value. 4. The total nitrogen in the liver, small intestine and serum of each diet group were no remarkable difference respectively. The contents of amino acid nitrogen in pf group for 2 and 6 weeks feeding were increased. 5. On transaminases: a) The cycle of increase and decrease of GPT activities were come periodically and the interval of cycle were fast in the early stage of feeding and slow there-after. b) The GPT activities were decreased gradually in pf group after feeding and those were increased in ib group for 6 weeks feeding but decreased there-after. The frequency of cycle were more GPT than GOT and specially those of GPT in early stage of feeding were two or three times while GOT was one. c) The interval of increase and decrease in GOT and amino acid nitrogen cycle were similar tendency. 6. The contents of total nitrogen, creatinine and urea-nitrogen of pf group in urine were decreased very sharply from sharting feeding to one week but increased dully from six weeks to eight weeks feeding. The contents of urea-nitrogen of ib group were increased dully by feeding on ten weeks but decreased by feeding on twelve weeks. From the above results, it is concluded that the trend of the metabolic change is maintained equally by homeostatic mechanism using the endogenous protein source during a certain period by imbalanced protein diet feeding. The homeostatic mechanism is come peridically, very fast in early stage of feeing and than slow there-after.

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.6
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• pp.1339-1348
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• 1999

In present study possible hypolipidemic effects of garlic were investigated in an experimental model which consisted of 4 groups of Wistar rats(three weeks old): CO group received a basal diet(as a standard diet) contained 6.3% of corn oil. LO group was taken the experimental diet in which only 6.3% corn oil in basal diet was substituted by 12.6% of lard oil. So the experimental diet was somewhat high saturated fat diet. LG1 group was treated orally with garlic juice as 1% of raw garlic in the diet together with the same diet as the diet for LO group. LG2 group was taken 2% of garlic under the same dietary condition as that of LG1 group. The rat body weights prior and posterior to the experimental period were measured and the amount of the experimental dietary intake was determined at every 3 day interval. After the experimental dietary period of 30 days the blood obtained from all the sacrificed rats were analyzed for the biochemical parameters. Over the one month period of experiment there was no abnormality or apparent change in appearance and activity or diet consumption in all experimental rat groups. LO group fed a diet rich in lard showed significantly increased body weight gain rate by 30% and also elevated levels of triglyceride, total cholesterol and LDL cholesterol by 29.9%, 27.4% and 62.3% respectively and no significant difference in the levels of HDL cholesterol, GOT, GPT, blood glucose and blood urea nitrogen as compared to those of control group. So it seemed that the high calorie diet in LO group mainly contributed to the significant increase in body weight gain rate and other biochemical parameters. In spite of 1% garlic treatment LG1 group had significantly increased body weight gain rate by 25.2%, levels of triglyceride, total choesterol and LDL cholesterol by 25.2%, 24.6% and 50.5% respectively as compared to control and LO group, and no increase in the levels of HDL cholesterol, blood glucose and blood urea nitrogen. At garlic 1% diet there was no hypolipidemic efficacy in rat serum. Under the treatment with garlic 2% in diet LG2 group showed significantly increased body weight gain rate by 19.7% as compared to control and elevated levels of GOT, GPT and BUN by 85.8~96.4%, 127~148% and 88% respectively as compared to control, but LG2 group had significantly reduced levels of triglyceride, total cholesterol and LDL cholesterol as compared to LOand LG1 group. In present study there were no significant change in HDL cholesterol and blood glucose value. In LG2 group GOT, GPT and blood urea nitrogen values were slightly increased presumably due to the inhibiting effects of garlic on the hepatic or renal function of rats. Nevertheless in this study garlic may have some demonstrable hypolipidemic effects in rat.

• Journal of Nutrition and Health
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• v.1 no.2
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• pp.93-105
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• 1968

The variations of both thiamine and riboflavin value in the organs, viz. liver, small intestine, spleen and kidney of the rats were measured for observing some metabolic changes in the animals during fasting and feeding different quality of diets without V-E supplement. The animal used for the experiment was adult female ablino rat from a pure strain, weighing 225-280g. The animals were divided into 6 groups; the control group, the high carbohydrate diet group, the high carbohydrate diet with V-E group, the high protein diet group, the high protein diet with V-E group, and fasting group. The result obtained are summarized as follows; 1. The thiamine contents in the liver were once increased during early stage of starvation compared with the control group, thereafter they were decreased on the 8 days fasting while the contents in the small intestine and spleen were decreased during 1 to 8 days fasting. 2. The riboflavin contents in the liver and kidney were increased during starvation and the content in the small intestine was no marked change compared with control group. 3. The thiamine contents in the liver and small intestine during feeding the high carbohydrate with V-E supplement diet group were lower than that of the diet without V-E group and the content in the spleen was increased by feeding V-E enriched high carbohydrate diet. 4. The thiamine contents in the liver, small intestine and spleen during feeding the V-E supplemented diets were lower than that of the non-supplemented one's. 5. The riboflavin contents in the liver, small intestine, and kidney were increased during feeding the high carbohydrate diet compared to the control group, and they were decreased during feeding the V-E enriched high carbohydrate diet. 6. The riboflavin contents in each organ were increased during feeding the high protein diet compared to the control group, and they were much increased during 20 to 30 days of feeding the V-E supplemented high protein diet. 7. Therefore, as the above results showed, the variation of thiamine value in the each organs were not markedly changed during feeding different quality of the diets. The thiamine and riboflavin contents in the each organ in the V-E enriched high carbohydrate diet group were lower than without V-E supplemented one's The riboflavin contents in each organ were increased during feeding the high protein diet compared with the control group and the centents were increased during 20 to 30 days of the feeding V-E enriched high protein diet.

• Journal of the Korean Applied Science and Technology
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• v.10 no.1
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• pp.39-47
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• 1993

This study was performed observe the effect of vegetable oil on the liver of 0.5% cholesterol-fed rats. In this experiment, male rats of Sprague-Dawley strain were used. The rats were divided into 5groups which were fed differently either for 8 weeks: basal diet, 20% sunflower oil diet, 20% soybean oil diet, 20% rapeseed oil diet.,20% coconut oil diet. The total cholesterol, triglyceride level in the liver were showed tendency of increase with increasing of P/S ratios. Bile acid excretion in the fecal increased with increasing of P/S ratios. The value of TBA in the serum and liver were increased in proportion to the amount of polyunsaturated fatty acid. The liver fatty acid of coconut-fed group showed larger variation than fatty acid of the cocount oil. The fat chang of sunflower oil diet in the liver showed the largest change.

• Journal of Sasang Constitutional Medicine
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• v.10 no.2
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• pp.305-349
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• 1998

We wanted to classify the food constitutionally. That was used to make the constitutional diet plan. And we checked through the clinical test. So the food was classified constitutionally by Sasang Constitutional Medicine(SCM). Constitutional diet plan was considered to Nutrition and Constitution. The clinical trial(use Taeumin diet plan) had performed during 8 weeks. We checked the Health and Nutrition condition. As the result, the Taeumin diet plan didn't change the health and nutrition condition of each constitution in good health. That could be presumed that constitution diet plan do not harm to healthy person.

• Asian-Australasian Journal of Animal Sciences
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• v.18 no.5
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• pp.637-642
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• 2005

The objective of this study was to evaluate the effect of dietary undegradable protein (UP) level on body weight change, nutrient intake, milk production and postpartum reproductive performance of Awassi ewes. Twenty-seven multiparous Awassi ewes (initial body weight = 53.3${\pm}$1.6 kg) were randomly assigned to three dietary treatments (9 ewes/treatment) for 62 days using a completely randomized design. Experimental diets were isonitrogenous (15.5% CP), isocaloric, and were formulated to contain 17.9 (LUP), 27.1 (MUP), and 34.0% (HUP) of the dietary CP as UP. On day 10${\pm}$3 (day 0 = parturition) ewes were housed in individual pens for 5 weeks. Feed offered and refused was recorded daily. At the end of this period, animals were removed from their pens and combined into 3 separate groups (LUP, MUP and HUP). One fertile, harnessed ram was allowed with each group for 34 days. Rams were rotated every 2 days among the three groups. Each group was offered the corresponding experimental diet. Organic matter, CP, UP and metabolizable energy intakes were higher (p<0.05) for ewes fed the HUP diet compared with ewes fed the LUP and MUP diets. Ewes fed the HUP diet gained more (p<0.05) weight compared with ewes fed the MUP diet (7.3 vs. 2.1 kg), while ewes fed the LUP diet lost an average of 2.1 kg. Pregnancy rate of ewes fed the HUP diet was 100%, compared with 66 and 33% for ewes fed the MUP and LUP diets, respectively. Lambing rate was greater (p<0.05) for ewes fed HUP (8/9) diet compared with ewes fed the MUP (4/9) and LUP (3/9) diets. These results indicate that Awassi ewes receiving adequate dietary UP level consume more feed and are capable of returning to estrus shortly after parturition and are capable of producing two lamb crops per year.

• Journal of Life Science
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• v.11 no.2
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• pp.126-132
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• 2001

Effect of Quartz porphyty(QP) on functional and morphological changes of the liver and kidney was studied in male common finch and white java sparrow fed with the basal diet(Control group) or experimental diet containing 3.0% QP(QP group) for 14 days. There was not significantly different morphological change of the liver upon light microscopic examination in common finch and white java sparrow between control group and QP group. Morphological change of renal tissue upon light microscopic examination in common finch and white java sparrow was not also significantly different between control group and QP group. The concentrations of serum creatinine, blood urea nitrogen, and nric acid as renal functional parameters of common finch and white java sparrow were not significantly different in the both groups. The activity of glutamic oxaloacetic transaminase(GOT) as hepatic functional parameter in common finch was significantly higher in the QP group($\rho$<0.05), whereas the activity of glutamic pyruvic transaminase(GPT) as hepatic functional parameter in common finch was not significantly different in the both groups. The activities of GOP and GPT in white java sparrow were not significantly different in the both groups. The morphologic findings and functional parameters of the liver and kidney observed in common finch and white java sparrow fed with 3.0% QP diet showed evidence of slightly liver damage accompanied with increased release of enzyme and fatty change of the hepatocytes in common finch, suggested that the tissues in some animals can be damaged by feeding a diet supplemented with 3.0% QP.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.3
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• pp.634-641
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• 2007

In order to investigate the effects of Bogigambi-tang(here in after referred to BGGBT) on the obese gene and obese inhibitory, C57BL/6 mice were induced by high fat diet. C57BL/6 mice were divided into three groups(normal, high fat diet with control, high fat diet with BGGBT extract) and fed for 15 weeks. Items of this experimental study are as follows. Body weight change, final inclose of body weight, the weight change of the adipocytes in body, the level change of ALT, AST, total cholesterol, LDL-Cholesterol, triglyceride, glucose, free fatty acid and creatinine, the expression of ${\beta}$3AR and leptin gene in primary adipocytes, the production change of leptin in primary adipocytes, the expression of ${\beta}$3AR and leptin in adipocytes tissue. The following results have been obtained All experimental group have shown that the weight and the final increase of weight have decreased considerably. All experimental group have shown that the amount of the adipocyte in weight has decreased considerably. All experimental group have shown that the amount of leptin has decreased considerably. All experimental group have shown that the revelation of ${\beta}$3AR in primary adipose cell and 3T3-L1 cell has increased considerably, and that the revelation of leptin in primary adipose cell and 3T3-L1 cell has decreased considerably, All experimental group have shown that the size of adipocyte in adipocytes tissue has decreased. The high density group have shown that the adipose vacuoles in liver tissue has decreased considerably, and that the cell nucleuses has similar with normal group.

• Korean Journal of Health Education and Promotion
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• v.23 no.4
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• pp.1-12
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• 2006

Objectives: The aim of this study was to investigate the effects of DASH diet and law salt diet health education program on the blood pressure and the diet habit in the prehypertension group in Korea. Methods: The participants in this study were 141 people with prehypertension who were seen at a public health center. Data collection was done from March 11 to November 11, 2005 using interview with questionnaires. The participants took part in the diet health education program for 8 weeks. In order to evaluate the effectiveness of health education program, the variables of the diet such as hypertension, law salt diet and DASH diet were measured before and after the health education. The blood pressure was measured three times during the education. The collected data were analyzed with paired t-test and repeated ANOVA using SPSS 12.0 for Windows. Results: The diet habit variables after the education showed that their diet habit tend to the low salt diet and the DASH diet. The participants improved in their knowledge of hypertension and law salt diet, and they improved in the behavioral level of law salt diet and DASH diet after the health education for 8 weeks. Systolic and diastolic pressure were significantly decreased in prehypertension group after 8 weeks [10mmHg/6mmHg(p<0.001)]. Conclusion: These result suggest that the improvement in the level of behavior might be related with the change in blood pressure among the people having prehypertension in Korea.