• Title/Summary/Keyword: Diagnostic validation

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The Software Reliability Evaluation of a Nuclear Controller Software Using a Fault Detection Coverage Based on the Fault Weight (가중치 기반 고장감지 커버리지 방법을 이용한 원전 제어기기 소프트웨어 신뢰도 평가)

  • Lee, Young-Jun;Lee, Jang-Soo;Kim, Young-Kuk
    • KIPS Transactions on Computer and Communication Systems
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    • v.5 no.9
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    • pp.275-284
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    • 2016
  • The software used in the nuclear safety field has been ensured through the development, validation, safety analysis, and quality assurance activities throughout the entire process life cycle from the planning phase to the installation phase. However, this evaluation through the development and validation process needs a lot of time and money, and there are limitations to ensure that the quality is improved enough. Therefore, the effort to calculate the reliability of the software continues for a quantitative evaluation instead of a qualitative evaluation. In this paper, we propose a reliability evaluation method for the software to be used for a specific operation of the digital controller in a nuclear power plant. After injecting weighted faults in the internal space of a developed controller and calculating the ability to detect the injected faults using diagnostic software, we can evaluate the software reliability of a digital controller in a nuclear power plant.

Screening Tool for Anxiety Disorders: Development and Validation of the Korean Anxiety Screening Assessment

  • Kim, Yeseul;Park, Yeonsoo;Cho, Gyeongcheol;Park, Kiho;Kim, Shin-Hyang;Baik, Seung Yeon;Kim, Cho Long;Jung, Sooyun;Lee, Won-Hye;Choi, Younyoung;Lee, Seung-Hwan;Choi, Kee-Hong
    • Psychiatry investigation
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    • v.15 no.11
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    • pp.1053-1063
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    • 2018
  • Objective This study evaluated the psychometric properties of the Korean Anxiety Screening Assessment (K-ANX) developed for screening anxiety disorders. Methods Data from 613 participants were analyzed. The K-ANX was evaluated for reliability using Cronbach's alpha, item-total correlation, and test information curve, and for validity using focus group interviews, factor analysis, correlational analysis, and item characteristics based on item response theory (IRT). The diagnostic sensitivity and specificity of the K-ANX were compared with those of the Beck Anxiety Inventory (BAI) and Generalized Anxiety Disorder 7-item scale (GAD-7). Results The K-ANX showed excellent internal consistency (${\alpha}=0.97$) and item-total coefficients (0.92-0.97), and a one-factor structure was suggested. All items were highly correlated with the total scores of the BAI, GAD-7, and Penn State Worry Questionnaire. IRT analysis indicated the K-ANX was most informative as a screening tool for anxiety disorders at the range between 0.8 and 1.6 (i.e., top 21.2 to 5.5 percentiles). Higher sensitivity (0.795) and specificity (0.937) for identifying anxiety disorders were observed in the K-ANX compared to the BAI and GAD-7. Conclusion The K-ANX is a reliable and valid measure to screen anxiety disorders in a Korean sample, with greater sensitivity and specificity than current measures of anxiety symptoms.

Validation of the Korean Version of the Talent Development Environment Questionnaire for Sport (한국판 스포츠영재육성환경질문지(TDEQ) 타당성 검증)

  • Choi, Young-Jun;Hwang, Seunghyun
    • 한국체육학회지인문사회과학편
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    • v.54 no.5
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    • pp.207-219
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    • 2015
  • The purpose of this study was to test the validation of the Korean version of the Talent Development Environment Questionnaire for sport(TDEQ; Martindale et al., 2010), developed through the conceptual and statistical verification stages(substantive stage-structural stage-external stage). In accordance with the procedure of translation, the substantive concepts of the items were reviewed. The data were collected from a sample of 244 ; 117 high school student-athletes and 127 university student-athletes. In order to test the internal structure of TDEQ, EFA/CFA, and internal consistency were performed. As a result, Korean version of the TDEQ had 5 factors with 38 items. External relationship by correlation analysis and group differentiation analysis were obtained to enhance the validity of the test. Overall, the Korean TDEQ will be used as a diagnostic and evaluation tool at the stage of detection, identification, selection, and development of Sport Talent.

Development and Validation of Core Competency Scale For Graduate Students in the Field of Science and Engineering (이공계열 대학원생 핵심역량 진단도구 개발 및 타당화 연구: A연구중심대학 사례)

  • Bae, Sang Hoon;Cho, Eun Won;Han, Song Ie;Jeong, Yoo Ji;Kim, Kyeong Eon
    • Journal of Engineering Education Research
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    • v.27 no.2
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    • pp.35-50
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    • 2024
  • The purpose of this study is to identify the core competencies of graduate students at A research university in the context of graduate education in science and engineering, and to develop and validate a diagnostic tool to measure them. To achieve the research objectives, first, 6 factors and 18 sub-competencies of core competencies were derived based on a review of domestic and foreign studies, cases of excellent research-centered overseas universities, and interviews with members of A University. Second, a theoretical model was constructed by deriving behavioral indicators based on the core competencies and sub-competencies, and a preliminary survey was conducted on 188 graduate students of University A to verify the statistical validity of the theoretical model. Results of exploratory and confirmatory factor analysis, the core competencies of graduate students at A research university consisted of 6 factors, 16 sub-competencies, and 77 items. Specifically, it included "Independent research capability(13 items)", "Social Entrepreneurship(10 items)", "Academic agility(15 items)", "Ingenious Challenges(15 items)", "Collegial Collaboration(9 items)", and "Mueunjae leadership(15 items)". This study contributes to the development of theories related to core competencies of graduate students in science and engineering, and has practical significance as a basis for a data-driven competency-based graduate education system.

Diagnosis and prediction of periodontally compromised teeth using a deep learning-based convolutional neural network algorithm

  • Lee, Jae-Hong;Kim, Do-hyung;Jeong, Seong-Nyum;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • v.48 no.2
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    • pp.114-123
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    • 2018
  • Purpose: The aim of the current study was to develop a computer-assisted detection system based on a deep convolutional neural network (CNN) algorithm and to evaluate the potential usefulness and accuracy of this system for the diagnosis and prediction of periodontally compromised teeth (PCT). Methods: Combining pretrained deep CNN architecture and a self-trained network, periapical radiographic images were used to determine the optimal CNN algorithm and weights. The diagnostic and predictive accuracy, sensitivity, specificity, positive predictive value, negative predictive value, receiver operating characteristic (ROC) curve, area under the ROC curve, confusion matrix, and 95% confidence intervals (CIs) were calculated using our deep CNN algorithm, based on a Keras framework in Python. Results: The periapical radiographic dataset was split into training (n=1,044), validation (n=348), and test (n=348) datasets. With the deep learning algorithm, the diagnostic accuracy for PCT was 81.0% for premolars and 76.7% for molars. Using 64 premolars and 64 molars that were clinically diagnosed as severe PCT, the accuracy of predicting extraction was 82.8% (95% CI, 70.1%-91.2%) for premolars and 73.4% (95% CI, 59.9%-84.0%) for molars. Conclusions: We demonstrated that the deep CNN algorithm was useful for assessing the diagnosis and predictability of PCT. Therefore, with further optimization of the PCT dataset and improvements in the algorithm, a computer-aided detection system can be expected to become an effective and efficient method of diagnosing and predicting PCT.

Development of Settlement Condition Diagnosis Index in Rural Village (정주체계를 고려한 농촌마을의 정주여건 진단지표 개발)

  • Park, Meejeong;Jeon, Jeongbae;Bae, Seoungjong;Kim, Daesik;Choi, Jinah;Kim, Eunja
    • Journal of Korean Society of Rural Planning
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    • v.23 no.1
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    • pp.65-83
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    • 2017
  • This paper proposes a village level settlement environment diagnostic indices in rural areas which can apply to analyze various conditions at village level. A living space in rural areas has been changed with a diverse aspect according to living infrastructure, industrial structure, accessibility to neighbor city and so on. This indicators considered these mega-regionalization of economy and lifestyle in rural areas. The indicators consists of basic indices for all types villages and convenience service indices for center villages and the other neighbor ones classified by a functionality of their convenience facilities. As the results of delphi expert survey and a field validation, rural village settlement environment diagnostic indicators were selected 3 types, 15 domains, 24 subdomains and 61 items. And these indicators weight were determinted by AHP method. These developed indicators were used to diagnosis settlement conditions of 31 villages, located on county of Yeongdong. to validate a applicability and feasibility.

Use of Cardiac Computed Tomography for Ventricular Volumetry in Late Postoperative Patients with Tetralogy of Fallot

  • Kim, Ho Jin;Mun, Da Na;Goo, Hyun Woo;Yun, Tae-Jin
    • Journal of Chest Surgery
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    • v.50 no.2
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    • pp.71-77
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    • 2017
  • Background: Cardiac computed tomography (CT) has emerged as an alternative to magnetic resonance imaging (MRI) for ventricular volumetry. However, the clinical use of cardiac CT requires external validation. Methods: Both cardiac CT and MRI were performed prior to pulmonary valve implantation (PVI) in 11 patients (median age, 19 years) who had undergone total correction of tetralogy of Fallot during infancy. The simplified contouring method (MRI) and semiautomatic 3-dimensional region-growing method (CT) were used to measure ventricular volumes. Results: All volumetric indices measured by CT and MRI generally correlated well with each other, except for the left ventricular end-systolic volume index (LV-ESVI), which showed the following correlations with the other indices: the right ventricular end-diastolic volume index (RV-EDVI) (r=0.88, p<0.001), the right ventricular end-systolic volume index (RV-ESVI) (r=0.84, p=0.001), the left ventricular end-diastolic volume index (LV-EDVI) (r=0.90, p=0.001), and the LV-ESVI (r=0.55, p=0.079). While the EDVIs measured by CT were significantly larger than those measured by MRI (median RV-EDVI: $197mL/m^2$ vs. $175mL/m^2$, p=0.008; median LV-EDVI: $94mL/m^2$ vs. $92mL/m^2$, p=0.026), no significant differences were found for the RV-ESVI or LV-ESVI. Conclusion: The EDVIs measured by cardiac CT were greater than those measured by MRI, whereas the ESVIs measured by CT and MRI were comparable. The volumetric characteristics of these 2 diagnostic modalities should be taken into account when indications for late PVI after tetralogy of Fallot repair are assessed.

Accuracy Validation of Urinary Flowmetry Technique Based on Pressure Measurement (수압 측정에 기반하는 요류검사의 정확도 검증)

  • Choi, Sung-Soo;Lee, In-Kwang;Kim, Kun-Jin;Kang, Seung-Bum;Park, Kyung-Soon;Lee, Tae-Soo;Cha, Eun-Jong;Kim, Kyung-Ah
    • Journal of Biomedical Engineering Research
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    • v.29 no.3
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    • pp.198-204
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    • 2008
  • Uroflowmetry is a non-invasive clinical test useful for screening benign prostatic hyperplasia(BPH) common in the aged men. The current standard way to obtain the urinary flow rate is to continuously acquire the urine weight signal proportional to volume over time. The present study proposed an alternative technique measuring pressure to overcome noise problems present in the standard weight measuring technique. Experiments were performed to simultaneously acquire both weight and pressure changes during urination of 9 normal men. Noise components were separated from volume signals converted from both weight and pressure signals based on the polynomial signal model. Signal-to-noise ratio was defined as the ratio of the energies between signal and noise components of the measured volume changes, which was 8.5 times larger in the pressure measuring technique, implying that cleaner signal could be obtained, more immune to noisy environments. When four important diagnostic parameters were estimated, excellent correlation coefficients higher than 0.99 were resulted with mean relative errors less than 5%. Therefore, the present pressure measurement seemed valid as an alternative technique for uroflowmetry.

Experimental and Numerical Validation of the Technique for Concrete Cure Monitoring Using Piezoelectric Admittance Measurements (어드미턴스 기반 콘크리트 경화 모니터링의 실험 및 수치적 검증)

  • Kim, Wan Cheol;Park, Gyuhae
    • Journal of the Korean Society for Nondestructive Testing
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    • v.36 no.3
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    • pp.217-224
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    • 2016
  • This paper presents a new technique for monitoring the concrete curing process using embedded piezoelectric transducers via admittance measurements. When a piezoelectric transducer is embedded in a structure, the electrical impedance (admittance) of the transducer is coupled with the mechanical impedance of the host structure, which allows monitoring of the structural condition. In this study, the admittance signatures are used for monitoring the concrete curing process. This new method is based on an admittance-based sensor diagnostic process, in which the capacitance values of the piezoelectric transducers are dependent on the strength of the host structure. We numerically and experimentally investigated the variations in capacitive value during the curing process. The results demonstrate that there is a clear relationship between the concrete curing status and the slope, this indicates that the proposed method could be efficiently used for monitoring the curing status of a concrete structure.

Clinical Validation of a Protein Biomarker Panel for Non-Small Cell Lung Cancer

  • Jung, Young Ju;Oh, In-Jae;Kim, Youndong;Jung, Jong Ha;Seok, Minkyoung;Lee, Woochang;Park, Cheol Kyu;Lim, Jung-Hwan;Kim, Young-Chul;Kim, Woo-Sung;Choi, Chang-Min
    • Journal of Korean Medical Science
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    • v.33 no.53
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    • pp.342.1-342.6
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    • 2018
  • We validated the diagnostic performance of a previously developed blood-based 7-protein biomarker panel, $AptoDetect^{TM}$-Lung (Aptamer Sciences Inc., Pohang, Korea) using modified aptamer-based proteomic technology for lung cancer detection. Non-small cell lung cancer (NSCLC), 200 patients and benign nodule controls, 200 participants were enrolled. In a high-risk population corresponding to ${\geq}55years$ of age and ${\geq}30pack-years$, the diagnostic performance was improved, showing 73.3% sensitivity and 90.5% specificity with an area under the curve of 0.88. $AptoDetect^{TM}$-Lung (Aptamer Sciences Inc.) offers the best validated performance to discriminate NSCLC from benign nodule controls in a high-risk population and could play a complementary role in lung cancer screening.