• 제목/요약/키워드: Diagnostic validation

검색결과 157건 처리시간 0.027초

Diagnostic for Smoothing Parameter Estimate in Nonparametric Regression Model

  • In-Suk Lee;Won-Tae Jung
    • Communications for Statistical Applications and Methods
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    • 제2권2호
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    • pp.266-276
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    • 1995
  • We have considered the study of local influence for smoothing parameter estimates in nonparametric regression model. Practically, generalized cross validation(GCV) does not work well in the presence of data perturbation. Thus we have proposed local influence measures for GCV estimates and examined effects of diagnostic by above measures.

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국내 우울증 평가도구 타당화 연구의 체계적 고찰-진단적 타당성을 중점으로 : 한국형 우울 선별 도구 개발을 위한 예비 연구 (A Systematic Review of Validation Studies on Depression Rating Scales in Korea, with a Focus on Diagnostic Validity Information : Preliminary Study for Development of Korean Screening Tool for Depression)

  • 정수연;김신향;박기호;제갈은주;이원혜;최윤영;이승환;최기홍
    • 대한불안의학회지
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    • 제13권2호
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    • pp.53-59
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    • 2017
  • Reliable and valid diagnostic screening tools in the primary care setting enable accurate estimation of depression in individuals at risk or in need of treatment, and provide patients with an opportunity to receive optimal treatments. Although there have been extensive studies on screening tools for depression used in domestic mental health settings, there is little consideration and lack of a thorough review of the diagnostic validity of screening tools. In the current review, we selected 13 representative screening tools for depression which were evaluated in a total of 19 validation studies conducted in Korea. We summarized DSM-5 target domains, diagnostic indices, sensitivity, specificity, cut-off scores, and diagnostic validity information for each tool. Finally, the depression measurement expert group was constituted to evaluate the current status of screening tools for depression, and their recommendations for a new screening tool were summarized. This study was conducted as part of the Mental Health Technology Development project to develop the Korean screening tool for depression (K-DEP).

A Brief Screening Tool for PTSD: Validation of the Korean Version of the Primary Care PTSD Screen for DSM-5 (K-PC-PTSD-5)

  • Jung, Young-Eun;Kim, Daeho;Kim, Won-Hyoung;Roh, Daeyoung;Chae, Jeong-Ho;Park, Joo Eon
    • Journal of Korean Medical Science
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    • 제33권52호
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    • pp.338.1-338.5
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    • 2018
  • The purpose of this study was to develop and evaluate psychometrically the Korean version of the Primary Care Posttraumatic Stress Disorder Screen for the Diagnostic and Statistical Manual-fifth edition (K-PC-PTSD-5). In total, 252 participants were interviewed with the Structured Clinical Interview for Diagnostic and Statistical Manual-fifth edition-research version (SCID-5-RV). The K-PC-PTSD-5 showed good internal consistency (${\alpha}=0.872$), test-retest reliability (r = 0.89), and concurrent validity (r = 0.81). A score of 3 was identified as the threshold for clinically significant posttraumatic stress disorder (PTSD) symptoms. Overall, the results indicate that the K-PC-PTSD-5 is a useful, timesaving instrument for screening PTSD symptoms.

Validation of Synovial Fluid Clinical Samples for Molecular Detection of Pathogens Causing Prosthetic Joint Infection Using GAPDH Housekeeping Gene as Internal Control

  • Jiyoung Lee;Eunyoung Baek;Hyesun Ahn;Youngnam Park;Geehyuk Kim;Sua Lim;Suchan Lee;Sunghyun Kim
    • 대한의생명과학회지
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    • 제29권4호
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    • pp.220-230
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    • 2023
  • Identification of the pathogens causing infection is important in terms of patient's health management and infection control. Synovial fluids could be used as clinical samples to detect causative pathogens of prosthetic joint infections (PJIs) using molecular diagnostic assays, therefore, normalization and validation of clinical samples are necessary. Microbial culture is considered the gold standard for all infections, including PJIs. Recently, molecular diagnostic methods have been developed to overcome the limitation of microbial culture. Therefore, guideline for validating clinical samples to provide reliable results of molecular diagnostic assays for infectious diseases is required in clinical field. The present study aimed to develop an accurate validating method of synovial fluid clinical samples using GAPDH gene as an internal control to perform the quantitative PCR TaqMan probe assay to detect pathogens causing PJIs.

ADEX 개발에 관한 연구 (A study on the development of ADEX)

  • 오재응;신준;한창수
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1992년도 한국자동제어학술회의논문집(국내학술편); KOEX, Seoul; 19-21 Oct. 1992
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    • pp.453-456
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    • 1992
  • Diagnostic prototype expert system was developed by analyzing the measured acoustical data of automobile. For the utilities of this system, 1/3 octave filter(band-pass filter) and A/D converter were used for data acquisition and then information was analyzed using signal processing technique and pattern recognition by Hamming network algorithm. In order to raise the reliability of the diagnostic results, fuzzy inference technique was applied and, the results were displayed as graphical method to help the novice in diagnostic field. The validation of this diagnostic system was checked through experiments and it showed and acceptable performance for diagnostic process.

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체액량 부족(Fluid volume deficit) ; 간호진단의 타당도 조사 연구 (Validity of nursing diagnosis : Fluid volume deficit)

  • 변영순;김숙영
    • 기본간호학회지
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    • 제1권2호
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    • pp.207-218
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    • 1994
  • A validation of the nursing diagnosis 'fluid volume deficit' was completed by using the diagnostic content validity method. Articles pertaining to fluid volume depletion were reviewed to identify the signs and symptoms used to describe the nursing diagnosis. The topics addressed in the articles included hypovolemic shock, hemorrhage, trauma, fluid balance, hydration, burn injury, thirst, dehydration. A validation instruments was constructed of 52 signs and symptoms. A validation tool was examined by expert nurses group who work on intensive care unit, kidney transplantation unit, internal medicine and general surgery unit. The study sample rated the signs and symptoms on a scale from one to five, evaluating their relevance to this diagnosis. Of the 52 signs and symptoms on the validation tool, 10 were categorized as critical indicators and 34 were categorized as defining characteristics.

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실시간 중합효소 연쇄반응을 활용한 생물작용제 검증시스템 연구 (A Study on the Validation system of Detection for Biological Agents Using Real-Time PCR)

  • 차영길;구본우;김성주;김남일;박한오
    • 한국군사과학기술학회지
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    • 제20권5호
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    • pp.726-732
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    • 2017
  • Bacillus anthracis, Vibrio cholerae, Variola virus and Shigella dysenteriae are classified as category A and B biological weapons. In this study suggest that 4 genes of Bacillus anthracis, 2 genes of Vibrio cholerae, 1 gene of Variola virus and 1 gene of Shigella dysenteriae were detective 50~500 fg of target DNA per reaction using real-time PCR based assay. Also analytical specificity did not show any cross-reactivity with other related bacteria. Reliable and one reaction could be effective early diagnostic and treatment for detection of unknown samples.

JPEG2000에서 시각적 무손실 임계값을 이용한 진단의료영상 압축기법 (Diagnostic Medical Image Compression Method using Visually Lossless Threshold on JPEG2000)

  • 봉정식;양기주;전준현
    • 한국통신학회논문지
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    • 제34권7C호
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    • pp.671-680
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    • 2009
  • 진단용 디지털 의료영상(CT, MRI)의 경우 일반 영상에 비해 막대한 데이터양으로 인하여 저장과 전송에 많은 문제점이 발생한다. 이러한 문제점을 극복하는 간단한 방법은 압축률을 증가시키는 것이다. 그럼에도 불구하고 정확한 진단을 위한 임상적언 판단을 요구한다. 본 논문의 목적은 고주파대역에서 시각적 무손실 임계필터링을 수행하므로써 무손실 JPEG2000의 압축 효율을 향상시키는 것이다. 제안방식은 5/3 가역 DWT(Digital Wavelet Transfrom)을 사용하였을 때 압축률에 따라 다른 부대역 임계값을 사용하며, 재생된 진단 CT 영상에 시각적 무손실의 고품질을 제공한다.

뉴로-퍼지 기법에 의한 자동차 진단 (Automobile diagnosis by euro-Fuzzy Technique)

  • 신준;오재응
    • 대한기계학회논문집
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    • 제16권10호
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    • pp.1833-1840
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    • 1992
  • 본 연구에서는 자동차의 발달에 따른 정비 전문가의 상대적인 능력 감퇴를 보 완하고 진단의 정확성을 높일 수 있도록 소음계측에 의한 인공 지능적 뉴로-퍼지 진단 기법을 연구하였다. 이를 위하여 진단결과에 영향을 미치는 많은 작용변수와 다양한 차량상태 등을 고려함으로서 보다 신뢰성 있는 결과를 산출해내기 위한 퍼지(fuzzy) 추론 방식의 판단법을 도입하였으며, 진단이 실패했을 경우나 입력된 데이터가 충분하 지 못할 경우에 시스템 자체의 지식을 확장시켜 나갈 수 있도록 해밍네트(hamming net )에 의한 패턴인식 기법을 적용하였다. 그리고 컴퓨터 시뮬레이션과 자동차를 대상 으로 고장진단 실험을 실시하여 기존의 진단기법과의 비교를 통한 뉴로-퍼지 진단기법 의 효율성과 알고리즘의 타당성을 검증하였다.