• 제목/요약/키워드: Diagnostic test accuracy

검색결과 272건 처리시간 0.028초

판정행렬을 기반한 일체형 PET-MRI의 폐암 진단 유용성 평가 (Evaluation of Usefulness for Diagnosis of Lung Cancer on Integrated PET-MRI Using Decision Matrix)

  • 김정수;양현진;김유미;권형진;박찬록
    • 대한방사선기술학회지:방사선기술과학
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    • 제44권6호
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    • pp.635-643
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    • 2021
  • The results of empirical researches on the diagnosis of lung cancer are insufficient, so it is limited to objectively judge the clinical possibility and utilization according to the accuracy of diagnosis. Thus, this study retrospectively analyzed the lung cancer diagnostic performance of PET-MRI (Positron Emission Tomography-Magnetic Resonance Imaging) by using the decision matrix. This study selected and experimented total 165 patients who received both hematological CEA (Carcinoembryonic Antigen) test and hybrid PET-MRI (18F-FDG, 5.18 MBq/kg / Body TIM coil. VIVE-Dixon). After setting up the result of CEA (positive:>4 ㎍/ℓ. negative:<2.5㎍/ℓ) as golden data, the lung cancer was found in the image of PET-MRI, and then the SUVmax (positive:>4, negative:<1.5) was measured, and then evaluated the correlation and significance of results of relative diagnostic performance of PET-MRI compared to CEA through the statistical verification (t-test, P>0.05). Through this, the PET-MRI was analyzed as 96.29% of sensitivity, 95.23% of specificity, 3.70% of false negative rate, 4.76% of false positive rate, and 95.75% of accuracy. The false negative rate was 1.06% lower than the false positive rate. The PET-MRI that significant accuracy of diagnosis through high sensitivity and specificity, and low false negative rate and false positive rate of lung cancer, could acquire the fusion image of specialized soft tissue by combining the radio-pharmaceuticals with various sequences, so its clinical value and usefulness are regarded as latently sufficient.

Screening Sarcopenia in Rural Community-Dwelling Older Adults in Korea

  • KIM, Mi-Kyoung;LEE, Ji-Yeon;GIL, Cho-Rong;KIM, Bo-Ram;CHANG, Hee-Kyung
    • International Journal of Advanced Culture Technology
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    • 제8권4호
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    • pp.64-76
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    • 2020
  • Purpose: Several screening tools have been developed to identify sarcopenia in rural community-dwelling older adults. We aimed to compare the diagnostic accuracy of two such tools, namely the SARC-F and SARC-CalF assessments. Methods: This cross-sectional study on 388 community-dwelling older adults comprised 254 women and 134 men with a mean age of 77.8 ± 6.26 year in Korea. We assessed muscle mass, muscle strength, and physical performance using a bioimpedance analysis device, hydraulic hand dynamometer, and 4 m gait speed test, respectively. Three widely-used diagnostic criteria [the Asian Working Group for Sarcopenia (AWGS), European Working Group on Sarcopenia in Older People, and the International Working Group on Sarcopenia] were applied. Sensitivity and specificity analyses were performed on the SARC-CalF and SARC-F tests. We used receiver-operating characteristic curves and the area under the curves (AUCs) to compare the diagnostic accuracy of the assessments with regard to sarcopenia. Results: An analysis using four sets of diagnostic criteria showed that the prevalence of sarcopenia was 27.6% to 41.0%. Using the AWGS 2019 criteria as a reference standard, the SARC-CalF had a sensitivity of 83.02% and a specificity of 53.71% in the entire study population, whereas the SARC-F had a sensitivity of 79.87% and a specificity of 41.92%. The AUCs for the SARC-CalF and SARC-F tests were 0.725 (95% confidence interval 0.678-0.769) and 0.645 (95% confidence interval 0.595-0.693), respectively (p<001). In the analyses using the other three diagnostic criteria, similarity was also confirmed. Conclusion: SARC-CalF showed better sensitivity than did SARC-F when diagnosing sarcopenia in rural community-dwelling older adults. Further studies are needed to verify this finding in different populations.

의약품 함량분석 정도관리에서의 변이 요인에 대한 통계분석 (Statistical Analysis on the Sources of Variance in Proficiency Test of Quantitative Analysis of Medicines)

  • 조정환
    • Journal of Pharmaceutical Investigation
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    • 제37권1호
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    • pp.27-37
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    • 2007
  • Proficiency test is an essential tool far ensuring analytical ability of analytical chemists and analytical institutes. Usually, the standard protocol for proficiency test is focused on acceptability of reported analytical results of participants by calculating z-scores and related diagnostic parameters. The ultimate goal of this process is to reveal the sources of variability of analytical results and to find the way to reduce their influence. In this study, the method of analysis of variance (ANOVA) was applied to the analytical data collected from qualify control departments of pharmaceutical companies in KyungIn province in Korea in the year of 2000. As influencing factors of variability of analytical results, the use of internal standards for liquid and gas chromatograpy, the educational and professional background of participants, geological locations and yearly production sizes of participating companies were evaluated. To evaluate the variability in accuracy of analytical results, absolute differences from sample mean and sample median were used and to evaluate variability in precision of individual participants, the reported standard deviation of each participant was used. As a result, the use of internal standards in gas chromatographic analysis, participants' academic background and the yearly production sizes of pharmaceutical companies showed statistically significant influence to the accuracy and the precision of the reported analytical results used in this study.

공기구동 게이트밸브의 운전 성능평가 방법에 관한 연구 (A Evaluation Method of Operational Performance for Air-operated Gate Valve)

  • 김대웅;박성근;강신철;김양석
    • 한국유체기계학회 논문집
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    • 제12권2호
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    • pp.31-38
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    • 2009
  • The valve performance has been evaluated from the theoretical equation based on design information such as packing thrust, spring preload and friction coefficient(${\mu}$). The accuracy of those data can be lower than that of vendor's initial design data. Especially, the friction coefficient can be degraded with time than the original condition and the valve performance calculated using the previous friction coefficient can not be available. Accordingly, this paper is describing a new performance evaluation method of valve based on diagnostic test data which are acquired from a site valve tested in static and dynamic conditions. Especially, this paper provides a new method using friction coefficient(${\mu}$) which is derived from the diagnostic test data acquired in the valve's design basis condition.

혈액암 인자 유효성 검증과 분류를 위한 진단 예측 알고리즘 성능 비교 분석 (Comparative Analysis of Diagnostic Prediction Algorithm Performance for Blood Cancer Factor Validation and Classification)

  • 정재승;주현수;조치현
    • 한국멀티미디어학회논문지
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    • 제25권10호
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    • pp.1512-1523
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    • 2022
  • Artificial intelligence application in digital health care has been increasing with its development of artificial intelligence. The convergence of the healthcare industry and information and communication technology makes the diagnosis of diseases more simple and comprehensible. From the perspective of medical services, its practice as an initial test and a reference indicator may become widely applicable. Therefore, analyzing the factors that are the basis for existing diagnosis protocols also helps suggest directions using artificial intelligence beyond previous regression and statistical analyses. This paper conducts essential diagnostic prediction learning based on the analysis of blood cancer factors reported previously. Blood cancer diagnosis predictions based on artificial intelligence contribute to successfully achieve more than 90% accuracy and validation of blood cancer factors as an alternative auxiliary approach.

Application of artificial intelligence for diagnosis of early gastric cancer based on magnifying endoscopy with narrow-band imaging

  • Yusuke Horiuchi;Toshiaki Hirasawa;Junko Fujisaki
    • Clinical Endoscopy
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    • 제57권1호
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    • pp.11-17
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    • 2024
  • Although magnifying endoscopy with narrow-band imaging is the standard diagnostic test for gastric cancer, diagnosing gastric cancer using this technology requires considerable skill. Artificial intelligence has superior image recognition, and its usefulness in endoscopic image diagnosis has been reported in many cases. The diagnostic performance (accuracy, sensitivity, and specificity) of artificial intelligence using magnifying endoscopy with narrow band still images and videos for gastric cancer was higher than that of expert endoscopists, suggesting the usefulness of artificial intelligence in diagnosing gastric cancer. Histological diagnosis of gastric cancer using artificial intelligence is also promising. However, previous studies on the use of artificial intelligence to diagnose gastric cancer were small-scale; thus, large-scale studies are necessary to examine whether a high diagnostic performance can be achieved. In addition, the diagnosis of gastric cancer using artificial intelligence has not yet become widespread in clinical practice, and further research is necessary. Therefore, in the future, artificial intelligence must be further developed as an instrument, and its diagnostic performance is expected to improve with the accumulation of numerous cases nationwide.

종합검진 후 지방간 환자의 복부 초음파 검사와 임상화학적 검사결과의 정확성 분석 (Analysis of the Accuracy about Abdominal Ultrasonography and Clinical Chemical Test with Fatty Liver Patients on the Medical Examination)

  • 김영재;송종남;김민의
    • 한국방사선학회논문지
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    • 제6권3호
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    • pp.183-189
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    • 2012
  • 초음파 검사는 복강내 장기를 검사하는 대표적인 영상의학검사의 한 분야이며. 혈액검사는 체내 이상 징후를 임상화학적으로 검사하는 대표적인 방법이다. 지방간의 진단은 주로 복부초음파 검사와 혈액검사를 동시에 실시하여 수행하며 두 검사의 결과를 바탕으로 진단을 하게 된다. 이 경우에 실시하는 혈액검사의 기준은 TBIL, TC, AST, ALT, ALP, GGT, TG, HDL-C, GLU의 값이다. 본 연구에서는 초음파 영상에서 지방간 진단을 받은 환자의 혈액검사 정확성을 분석하여 두 종류의 검사간 정확도를 분석하고자 하였다. 2012년 1월부터 3월간 종합검진으로 복부초음파검사와 혈액검사를 동시에 받은 환자 1350명 중 초음파 검사상 지방간 판정을 받은 459명을 대상으로 초음파 검사와 혈액검사 결과가 동일한 경우는 459명 중 280명으로 약 60.8% 이며, 초음파 검사와 혈액검사의 결과가 서로 다른 경우는 179명으로 39.2%로 밝혀져 초음파 검사와 혈액검사의 진단 정확도는 60.8% 이었다. 이는 지방간의 초음파 진단시 종사자의 주관적 능력이 병변의 진단에 큰 영향을 미친 것으로 생각되어 지속적인 초음파 임상 교육이 필요할 것으로 사료된다.

다구찌 방법을 이용한 공정변수의 최적화

  • 이수호;박원식;조형석
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 1995년도 추계학술대회 논문집
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    • pp.907-910
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    • 1995
  • Though SLA(Stereolithography Apparatus) is being recognized as an innovative technology, it still can not be used to fully practical applications since it lacks of dimensional accuracy compared to conventional processes. In SLA, the accuracy of cured part depends upon the set of process parmeters. In order to improve the accuracy of SLA, this paper quantitatively evaluates how largely each process parameter of SLA contributes to the part accuracy and estimates the optimal set of process parameter which minimizes the dimensional errors of the test part, "letter-H" part. For this purpose, we use ANOVA(analysis of variance) and S/N(signal-to-noise)ratio of Taguchi method.hi method.

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단축형 사상체질 진단설문지(KS-15)의 문항 축소 연구 (The Reduction of Question Items in Korea Sasang Constitutional Diagnostic Questionnaire (KS-15))

  • 김상혁;박기현;백영화;장은수;이시우
    • 사상체질의학회지
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    • 제32권1호
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    • pp.30-38
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    • 2020
  • Objectives The purpose of this study is to reduce the question items in Korea Sasang Constitutional Diagnostic Questionnaire (KS-15) and to assess the validity. Methods The subjects of this study were 1,553 people who had information on body shape, personality, and symptoms among the data established at the Korean Medicine Data Center. Among them, 155 people were separated into a test group to assess the validity, and the remaining 1,398 were used as training groups for model development. The reduction question items were finally confirmed through discussion by two experts. The model development went through Multinomial Logistic Regression. Results & Conclusions The Percent Correctly Predicted (PCP) in the test group was 60.00% (58.49% in men and 60.78% in women). The PCP of each constitution was 72.6% in Taeeumin, 53.3% in Soeumin, and 50% in Soyangin. The accuracy rate of KS-10 seems to be reasonable considering the ease of use of reduced time required.

Effect of titanium and stainless steel posts in detection of vertical root fractures using NewTom VG cone beam computed tomography system

  • Mohammadpour, Mahdis;Bakhshalian, Neema;Shahab, Shahriar;Sadeghi, Shaya;Ataee, Mona;Sarikhani, Soodeh
    • Imaging Science in Dentistry
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    • 제44권2호
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    • pp.89-94
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    • 2014
  • Purpose: Vertical root fracture (VRF) is a common complication in endodontically treated teeth. Considering the poor prognosis of VRF, a reliable and valid detection method is necessary. Cone beam computed tomography (CBCT) has been reported to be a reliable tool for the detection of VRF; however, the presence of metallic intracanal posts can decrease the diagnostic values of CBCT systems. This study evaluated and compared the effects of intracanal stainless steel or titanium posts on the sensitivity, specificity, and accuracy of VRF detection using a NewTom VG CBCT system. Materials and Methods: Eighty extracted single-rooted teeth were selected and sectioned at the cemento-enamel junction. The roots were divided into two groups of 40. Root fracture was induced in the test group by using an Instron machine, while the control group was kept intact. Roots were randomly embedded in acrylic blocks and radiographed with the NewTom VG, both with titanium and stainless steel posts and also without posts. Sensitivity, specificity, and accuracy values were calculated as compared to the gold standard. Results: The sensitivity, specificity, and accuracy of VRF diagnosis were significantly lower in teeth with stainless steel and titanium posts than in those without posts. Interobserver agreement was the highest in teeth without posts, followed by stainless steel posts, and then titanium posts. Conclusion: Intracanal posts significantly decreased the VRF diagnostic values of CBCT. The stainless steel posts decreased the diagnostic values more than the titanium posts.