• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제11권sup2호
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• pp.29-34
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• 2008

소아에서의 급성 상부 위장관 출혈은 흔하지는 않지만 잠재적으로 심각한 위험을 초래할 수 있는 문제이다. 상부 위장관 출혈의 원인은 환아의 연령에 따라 다양하기 때문에 소아 환자를 평가할 때는 각 연령대 별로 흔한 특정 원인들을 미리 염두에 두는 것이 필요하다. 환자의 상태가 위중할 때는 신속한 병력 청취와 활력 징후 측정, 정맥 확보 및 특정 검사 등이 빠른 시간내에 이루어지는 것이 중요하다. 응급 상황에서는 기도 확보, 호흡, 순환 등 초기 심폐소생술을 먼저 시행한 후에 자세한 병력 청취, 신체 검사와 함께 상부 위장관 출혈을 일으킨 기저 질환을 확인하기 위하여 더 자세한 특수한 진단적 검사 등이 필요하고, 이를 근거로 각각의 원인에 따른 적절한 치료가 시행되어야 한다.

• 한국대기환경학회지
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• 제22권1호
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• pp.135-143
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• 2006

The objective of this study is to develop PSCF (potential source contribution function) program and determine the optimal values of control parameters to enhance the prediction of PSCF modeling. This study provides an important information and methodologies that can be used to get better results of locating influencing sources, especially unknown and fugitive sources. To determine proper values of control parameters in PSCF model, the diagnostic assessment on the results obtained by the various input conditions was carried out. PSCF model has created and improved from version 1.0 to version 7.0 since 200 I and the measured data (at least > 100) of receptor, and the values of control input parameters should be arranged and determined to obtain reliable results in PSCF modeling. The size of modeling domain must be determined to include enough trajectories to get reliable results. And the size of grid is recommended to be 2.5 $\sim$ 5 degrees for global scale, 0.2 $\sim$ 1 degrees for regional scale and 0.05 degree for local scale.

• 한국대기환경학회지
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• 제32권4호
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• pp.408-421
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• 2016

Day and night sampling for gas and particle phases PAHs were carried out in Seoul to characterize gas and particle phases PAHs concentrations in day and night times. There was no significant difference between day and night time for particle phase PAHs concentrations and phase distribution of PAHs, while, gas phase PAHs concentrations in daytime were about 1/2 of nighttime concentrations in both summer and winter due to photochemical reaction of gas phase PAHs during daytime. A high fraction of cancer risk for PAHs was attributed to particle phase PAHs and the excess cancer risk in winter was higher than in summer. The excess cancer risk level of total(gas+particle) PAHs in summer was partially observed when both gas and particle phase PAHs concentrations were considered as risk assessment. Based on the diagnostic ratios and factor analysis of PAHs concentrations, combustion(coal and natural gas) and vehicular emission might be the most significant contributors of PAHs and major factors for determining of PAHs concentration were different between day and night times.

• 대한의용생체공학회:의공학회지
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• 제7권2호
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• pp.139-146
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• 1986

본 논문은 tms 32010이라는 디지탈 신호 처리용소자를 사용하여 초음하 펄스 도플러 장치를 구현한 것이다. 도플러 장피란 초음파 신호의 송수신 과정에서 발생하는 도플러 효과를 이용하여 혈류의 속도를 측정하는 장치이다. 한 점에서의 속도를 측정하는 단일채널 도플러 장치에서는 실시간 고속 푸리에 변환기를 구현하여 도플러 주하수의 스펙트럼을 측정함으로서 혈류속도를 측정하며 초음파 빔의 일직선상에서의 여러점을 동시에 측정하는 다중채널 도플러 장치에서는 영점교차검출기를 구현하여 평균주파수를 측정하였다. 자중채널 장치는 직렬처리법을 사용하여 하드웨어를 간단히 하였으며 8점에서의 속도를 측정할 수 있도록 하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7261-7264
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• 2013

Recent genome wide sequencing has identified mutations in IDH1/IDH2 predominantly in grade II-III gliomas and secondary glioblastomas which are associated with favorable clinical outcome. These mutations have become molecular markers of significant diagnostic and prognostic relevance in the assessment of human gliomas. In the current study we evaluated IDH1 (R132) and IDH2 (R172) in 32 gliomas of various grades and tumor subtypes. Sequencing analysis revealed R132H mutations in 18.7% tumors, while none of the cases showed IDH2 (R172) mutations. The frequency of IDH1 mutations was higher in females (21.4%) than males (11.1%), and it was significantly higher in younger patients. Histological analyses demonstrated presence of necrosis and micro vascular proliferation in 69% and 75% respectively. Interestingly, IDH1 mutations were predominantly present in non-necrotic tumors as well as in cases showing microvascular proliferation. Of the six IDH1 positive cases, three were glioblastomas (IV), and one each were anaplastic oligoastrocytoma (III), anaplastic oligodendroglioma III (n=1) and diffuse astrocytoma. In conclusion, IDH1 mutations are quite frequent in Indian glioma patients while IDH2 mutations are not observed. Since IDH mutations are associated with good prognosis, their use in routine clinical practice will enable better risk stratification and management of glioma patients.

• 대한한의학회지
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• 제41권2호
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• pp.122-136
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• 2020

Objectives: A case report is a detailed report of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient. The purpose of this study is to evaluate the quality of case reports from the Journal of Korean Medicine by the CARE (CAse REport) Guideline. Methods: Case reports published in the Journal of Korean Medicine from January 2016 to March 2020 were searched from Oriental Medicine Advanced Searching Integrated System (OASIS). We assessed the quality of reporting based on CARE (CAse REport) guideline as 'Sufficient', 'Not-Sufficient' and 'Not-Report'. Results: A total of 22 case reports were finally included for the assessment. The reporting items were reported as of reporting quality. After checking the result, there was a deviation in the sub-item reporting rate by a maximum 89.29%, a minimum 66.67% and a median 82.14% in case reports. Also after checking the quality in case reports by 28 detailed items in CARE guidelines, there were not reported 77% or more in the 5 sub-items 'Intervention adherence and tolerability', 'Informed consent', 'Adverse and unanticipated events', 'Diagnostic challenges', 'Patient perspective'. Conclusion: There is a need to improve the quality of case reports in the journal of Korean Medicine based on various studies using CARE guideline.

• 대한한방소아과학회지
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• 제15권2호
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• pp.141-165
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• 2001

Attention-deficit/hyperactivity disorder(ADHD) is one of the most common childhood-onset psychlatric disorders. It is distinguished by symptoms of inattention, hyperactivity, and impulsivity. ADHD may be accompanied by learning disabilities, depression, anxiety, conduct disorder, and oppositional defiant disorder. The etiology of ADHD is unknown, and the disorder may have several different causes. Individual with ADHD present in childhood and may continue to show symptoms as they enter adolescence and adult life. Public interest in ADHD has increased along with debate in the media concerning the diagnostic process and treatment strategies. The purpose of this study is oriental medical approach to ADHD. This study was progressed for oriental diagnosis and treatment for ADHD. In oriental medicine, the reason of ADHD was deficiency of the kidney, hyperactivity of the liver(腎虛肝亢), deficiency of the heart and the spleen(心脾不足), heart disturbed by phlegm and heat(痰熱擾心). The method of medical treatment was nourishing the kidney and checking exuberance of yang(滋腎潛陽), relieving mental stress and promoting wisdom(寧神益智), nourishing the heart and strengthening the spleen(養心健脾), tranquilzation(安神定志). removing heat-phlegm(淸熱化痰), inducing resuscitation and tranquilzation(開窮安神). The prescription was commonly used as Liuwei Dihuang Wan jiajian(六味地黃丸加減), Guipi Tang he Ganmai Dazao Tang jiajian(歸脾湯合甘麥大棗湯加減), Huanglian Wendan Tang jiawei(溫黃連溫膽湯加味). It should help primary care providers in their assessment of a common child health problem.

• Journal of Chest Surgery
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• 제26권3호
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• pp.209-213
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• 1993

The pathogenesis of the primary spontaneous pneumothorax is the rupture of subpleural bleb or bullae and subsequent sudden collapse of the affected lung. Mostly, the bullae or blebs are present bilaterally, but detecting the number, size, and location of the causating foci by plain chest film is quite difficult . We have performed chest CT scans for detecting the bullous lesions in 33 cases of primary spontaneous pneumothorax, and compared the results with surgical findings.1. Seventy-four blebs were identified in the chest CT scan, and 100 blebs or bullae were detected surgically [ Sensitivity was 0.74 ].2. Diagnosis rate was 80% [40/50] at right upper lobe, 75.7% [28/37] at left upper lobe, 55.6% at right lower lobe, and 25.0% at left lower lobe, respectively.3. Blebs or bullae smaller than 1 cm of its diameter were detected by 57.1% [24/42] of sensitivity, and in the cases of size larger than 1 cm, it revealed 86.2% [50/58] of sensitivity respectively.4. Of the 45 cases, 7 cases were false negative [15.6%], most of these were ruptured or small size [< 0.5 cm]. 5. One case was false positive, which was irregular adhesion at the apex of the lung.6. We could detect blebs or bullae with preoperative CT scans in 84.4% [38/45] of total patients. In conclusion, chest CT scan is a very advantageous diagnostic tool for proper management and preventing recurrence of primary spontaneous pneumothorax patient.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.351-354
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• 2013

Objective: To assess the practical utility of pleural fluid carbonic anhydrase XII (CAXII) quantification for differential diagnosis of effusions. Materials and Methods: Fluid was collected prospectively from fifty patients presenting with lymphocytic pleural effusions for investigation and CAXII was quantified by ELISA. Results: Pleural fluid CAXII concentrations were significantly higher in lung cancer patients (n=30) than in tuberculous controls (n=20). The sensitivity and specificity of this biomarker were 60%and 75%, respectively. CAXII measurement was not inferior to cytological examination in the diagnosis and exclusion of pleural effusions from lung cancer patitents (sensitivity 60% vs. 57%; specificity 75% vs. 100%; positive predictive value 77%; negative predictive value 54%). In patients with negative cytology, it offered a sensitivity of 54%. Conclusions: Pleural fluid CAXII is elevated in pleural effusions from lung cancer patients. Measurement of CAXII may be used in the future as a valuable adjunct to cytology in the diagnostic assessment of patients with pleural effusions related to lung cancer, especially when cytological examination is inconclusive.

• 품질경영학회지
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• 제44권2호
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• pp.277-296
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• 2016

Purpose: Propose model to diagnose and assess National Defense Industry and quality management by investigating and analyzing established standard model. Methods: Research on established internal model including MB, EQA and JQA model and make standard index for quality index extraction and quantitative index to test objectively for internal state. Results: Extract advantage and disadvantage by performance of National Defense Industry level diagnose and build foundation for quality management policy and road map. Conclusion: Due to result of diagnostic assesment of quality management of national defense industry, dependability, SCQM and safety part shows vulnerability and require improvement and support.