• The Journal of Internal Korean Medicine
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• v.36 no.2
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• pp.85-92
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• 2015

Objectives: The liver fibroscan has been developed as a noninvasive and convenient method to assess hepatic fibrosis. This study aimed to review this device in terms of its technological concept and clinical application in traditional Korean medicine (TKM). Methods: The technological background, diagnostic evaluation, and clinical usefulness of fibroscan were reviewed using various literature and clinical studies. One clinical example-a patient with hepatofibrosis who had been treated with TKM-is presented. Results: The liver fibroscan was approved as a medical device for noninvasive measurement of the hepatic fibrosis level by the Korean Food and Drug Administration (KFDA). Numerous clinical studies have confirmed that its sensitivity and specificity allow it to serve as a substitute for liver biopsy, the present gold standard diagnostic method. The accuracy and reproducibility and lack of technical risks are strong points of the fibroscan; however, it has some limitations for application, especially in patients with obesity or severe hepatitis. One clinical example showed the applicability of the liver fibroscan in herbal medicine-based treatments. Conclusions: The requirement for diagnostic medical devices is an important issue in TKM; therefore, this study provides valuable information for practitioners of TKM.

• Korean Journal of Veterinary Research
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• v.58 no.1
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• pp.27-31
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• 2018

Canine coronavirus is a single-stranded RNA virus that causes enteritis in dogs of any age. Coronaviral enteritis is seldom definitively diagnosed, since it is usually much less severe than many other types of enteritis and is self-limiting. Conventional diagnostics for the canine coronaviral enteritis such as polymerase chain reaction (PCR), virus isolation, and electron microscopic examination are inappropriate for small animal clinics due to the complicated experimental processes involved. Therefore, a commercially available lateral flow test kit based on chromatographic immunoassay techniques was tested to evaluate its performance as a first-line diagnostic test kit that could be used in clinics. The coronavirus antigen test kit detected canine coronavirus-infected dogs with 93.1% sensitivity and 97.5% specificity. The detection limit of the test kit was between $1.97{\times}10^4/mL$ and $9.85{\times}10^3/mL$ for samples with a 2-fold serial dilution from $1.25{\times}10^6\;TCID_{50}$ ($TCID_{50}$, 50% tissue culture infectious dose). Additionally, the test kit had no cross-reactivity with canine parvovirus, distemper virus, or Escherichia coli. Overall, the commercially available test kit showed good diagnostic performance in a clinical setting, with results similar to those from PCR, confirming their potential for convenient and accurate use in small animal clinics.

• Korean Journal of Digital Imaging in Medicine
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• v.6 no.1
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• pp.9-18
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• 2003

디지털 영상 검출기와 디스플레이 기술의 발달과 의료영상전달시스템(PACS)의 출현은 전통적 필름방식에 비하여 디지털 방식으로 방사선과 영상을 획득하고 전송, 저장하는 매우 효과적인 수단을 제공하고 있다. 2002년 8월, 연세의료원 세브란스병원은 진단 영상 판독 목적으로 18 대의 CRT(Braco View, Belgium)와 32대의 평판 LCD(Totoku Electric Co., Ltd., Japan) 디스플레이 장치를 GE full-PACS(GE 메디칼시스템코리아 : GEMSK)와 연계하여 설치 완료하였다. 본 연구에서, 기하학적 왜곡, 반사, 휘도 반응, 휘도 균일도, 분해능, 노이즈,베일링 글레어, 칼라 균일도 항목들을 AAPM TG18 보고서 9.0에 따라서 시각적 그리고 부분적으로는 정량적인 방법으로 인수검사를 실시하여 보고한다. 사용된 장비는 색도계로도 사용되는 간편한 휘도계, TG18 테스트 패던, AAPM Tg18 AT plug-in software(Barco View Ltd., Kortrijk, Belgium)이었다. 칼라 균일도를 제외한 모든 테스트 결과는 AAPM TG18에서 권고하는 기준에 일치하였으며 진단 영상 판독에 사용하기에 전적으로 수락할 수 있는 성능이었다. 결론으로, 사용된 인수검사는 단지 인수 검사 표준을 제공하는 것 뿐만 아니라 품질검사(QC)의 지침, 판독 환경의 최적화 그리고 교체 시기나 업그레이드 시기를 결정하여주는 중요한 역할을 할 수 있을 것이다.

• Korean Journal of Bronchoesophagology
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• v.17 no.1
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• pp.9-13
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• 2011

Endobronchial ultrasound (EBUS), which enables visualization of lesions beyond the bronchus, broadens the fields of bronchoscopy. Two types of ultrasound, radial and linear, are used for bronchoscopy. Radial EBUS is performed by inserting an ultrasound mini-probe through the working channel of a flexible bronchoscope. Evaluation of the depth of invasion of early endobronchial lung cancers using radial EBUS is useful in deciding endobronchial treatment. A central tumor limited to within the cartilaginous layer is a good indication for endobronchial photodynamic therapy. EBUS-guide sheath (GS) technique is a sampling method assisted by localization of peripheral lesions using EBUS. The diagnostic yield of EBUS-GS method is higher than that of conventional transbronchial biopsy. High diagnostic values of EBSU-GS method are reported even in small (${\leq}2cm$) peripheral tumors. Linear EBUS is used for endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA). EBUS-TBNA has high diagnostic yields in mediastinal staging of lung cancer even in patients having radiologically early stage lung cancers with normal CT or PET findings in the mediastinum. EBUS is a valuable method in evaluating early endobronchial tumors and peripheral small lung cancers and as well as in mediastinal staging.

• Imaging Science in Dentistry
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• v.46 no.2
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• pp.141-144
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• 2016

The aim of this report is to present two cases of canalis basilaris medianus as identified on cone-beam computed tomography (CBCT) in the base of the skull. The CBCT data sets were sent for radiographic consultation. In both cases, multi-planar views revealed an osseous defect in the base of the skull in the clivus region, the sagittal view showed a unilateral, well-defined, non-corticated, track-like low-attenuation osseous defect in the clivus. The appearance of the defect was highly reminiscent of a fracture of the clivus. The borders of osseous defect were smooth, and no other radiographic signs suggestive of osteolytic destructive processes were noted. Based on the overall radiographic examination, a radiographic impression of canalis basilaris medianus was made. Canalis basilaris medianus is a rare anatomical variant and is generally observed on the clivus. Due to its potential association with meningitis, it should be recognized and reported to avoid potential complications.

• Journal of Korean Institute of Industrial Engineers
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• v.30 no.1
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• pp.44-49
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• 2004

The aim of this study is to compare the methods in analyzing bio-signals representing measure driver's psychophysiological staus. This study has considered three approaches: first, the deterministic approach calculating the mean and standard deviation of bio-signal, second, probabilistic approach converting driver's bio-signal values to probability density function and identifying individual state relative to overall distribution, and third, diagnostic approach identifying the pattern change of signal over certain period of time. For evaluation of analysis methods, driver's bio-signal was collected under various road conditions, and three analysis approaches were applied respectively. In result, the deterministic approach was found to be simple to use, but generated a large variability of bio-signal. The probabilistic approach provide a relative status of individual driver among overall population, but too much affected by temporal variability of individual driver. The diagnostic approach seemed to reasonably find driver's psychophysiological change over certain period of time, but still needs to develop quantification method of the bio-signal.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2010.11a
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• pp.499-505
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• 2010

The UAV(Unmanned Aerial Vehicle) which is remotely operating with long endurance in high altitude must have a very reliable propulsion system. The precise fault diagnostic system of the turboprop engine as a propulsion system of this type UAV can promote reliability and availability. This work proposes a diagnostic method which can identify the faulted components from engine measuring parameter changes using Fuzzy Logic and quantify its faults from the identified fault pattern using Neural Network Algorithms. It is found by evaluation examples that the proposed diagnostic method can detect well not only single type faults but also multiple type faults.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.14 no.1
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• pp.70-78
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• 2010

Objectives : To qualify or enhance the diagnostic ability of students in Oriental Medicine, so called standardized patients are ideal modality, but because it's a man-based method, more convenient tools are required. Computer-based diagnostic ability test program gives effective way for the very purpose. So we made a pilot software evaluating Pattern Identification ability in Oriental Medicine. Methods and Materials : The pilot software was coded with Microsoft's EXCEL VBA. 87 names of Zheng (Symptom Pattern) and 674 names of symptom (including some signs) are adopted from the former standardization works conducted by Korean Institute of Oriental Medicine (KIOM) in 1996. Results : Compared with some manned modalities to test Pattern Identification ability, the test by this software shows superiority in convenience and objectivity. Conclusion : This software is world's first program to perform computer-based evaluation of Pattern Identification in Oriental Medicine, and it gives effective way to complement both written test and manned clinical performance test (CPX).

• Journal of Korean Neurosurgical Society
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• v.39 no.6
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• pp.423-426
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• 2006

Objective : There is still debate about the diagnostic efficacy of digital infrared thermographic imaging[DITI], nevertheless, it has been used for the diagnosis of carpal tunnel syndrome[CTS]. We performed comparative study between patient and control groups to investigate the diagnostic value of DITI in CTS. Methods : We studied 27 patients with electrodiagnostically-proven CTS and 18 symptom-free volunteers as a control. We measured thermal difference on DITI in the corresponding regions of the hands and forearms. We statistically analyzed the thermal data using a t-test. Results : The average thermal difference in the diagnosed patient group ranged from $0.0303^{\circ}C$ to $0.2856^{\circ}C$, while that in control group ranged from $0.0611^{\circ}C$ to $0.2878^{\circ}C$. In the CTS patient group, thermal difference between each 2nd finger was higher than that of other regions. However, there was no statistical significance between patient and control groups. Conclusion : We found that the diagnostic value of DITI in CTS was not sufficient. There should be a reconsideration of the usefulness of DITI in CTS.

• Journal of radiological science and technology
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• v.42 no.5
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• pp.365-371
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• 2019

We have developed and applied a diagnostic Multi-Leaf Collimator (MLC) to optimized the X-ray field in medical imaging and the usefulness evaluated through the fusion of infrared image and X-ray image acquired by infrared camera. The hand and skull radiography with multi-leaf collimator(MLC) showed significant area dose reductions of 22.9% and 31.3% compared to ARC and leakage dose was compliant with KS A 4732. Also scattering doses of 50 cm and 100 cm showed a significant decrease to confirm the usefulness of MLC. It was confirmed that the fusion of infrared images with an adjustable degree of transparency was possible in the X-ray images. Therefore, fusion of anatomical information with physiological convergence is expected to contribute and improvement of diagnostic ability. In addition, the feasibility of convergence X-ray imaging and DITI devices and the possibility of driving MLC with infrared images were confirmed.