• Title/Summary/Keyword: Diagnostic Evaluation

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A Case of Benign Parotid Tumor Misdiagnosed for Parotid Cancer on Preoperative Cytology (수술 전 세침흡인세포검사에서 악성으로 의심되었던 이하선 양성 종양 1예)

  • Lee, Eun Jung;Hwang, Hye Jin;Byeon, Hyung Kwon
    • Korean Journal of Head & Neck Oncology
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    • v.31 no.1
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    • pp.9-13
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    • 2015
  • Fine needle aspiration cytology as a diagnostic workup of parotid gland tumor is a simple and useful method. Although fine needle aspiration cytology could not predict accurate diagnosis in all cases, it is usually helpful in differentiating malignancy and benign lesions. A 35-year-old female was found to have a parotid mass for 1 year. Preoperative evaluation including computed tomography and magnetic resonance imaging were non-diagnostic, but, fine needle aspiration cytology on parotid mass showed the suspicion of a low-grade mucoepidermoid carcinoma. Superficial parotidectomy and selective neck node dissection were done based on cytology. However, final pathological examination confirmed benign pleomorphic adenoma. Here, the diagnostic accuracy and cautions in interpretation of result of fine needle aspiration cytology is discussed with respect to the case.

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Construction of Probability Identification Matrix and Selective Medium for Acidophilic Actinomycetes Using Numerical Classification Data

  • Seong, Chi-Nam;Park, Seok-Kyu;Michael Goodfellow;Kim, Seung-Bum;Hah, Yung-Chil
    • Journal of Microbiology
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    • v.33 no.2
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    • pp.95-102
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    • 1995
  • A probability identification matrix of acidophilic Streptomyces was constructed. The phenetic data of the strains were derived from numerical classification described by Seong et al. The minimum number of diagnostic characters was determined using computer programs for calculation of different separation indices. The resulting matrix consisted of 25 clusters versus 53 characters. Theoretical evaluation of this matrix was achieved by estimating the chuster overlap and the identification scores for the Hypothetical Median Organisms (HMO) and for the representatives of each cluster. Cluster overlap was found to be relatively small. Identification scores for the HMO and the randomly selected representatives of each cluster were satisfactory. The matrix was assessed practically by applying the matrix to the identification of unknown isolates. Of the unknown isolates, 71.9% were clearly identified to one of eight clusters. The numerical classification data was also used to design a selective isolation medium for antibiotic-producing organisms. Four chemical substances including 2 antibiotics were determined by the DLACHAR program as diagnostic for the isolation of target organisms which have antimicrobial activity against Micrococcus luteus. It was possible to detect the increased rate of selective isolation on the synthesized medium. Theresults show that the numerical phenetic data can be applied to a variety of purposes, such as construction of identification matrix and selective isolation medium for acidophilic antinomycetes.

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Diagnostic Value of Computed Tomography in Acetabular Fracture (관골구 골절에서의 전산화단층촬영술의 진단적 가치)

  • Kim, Sun-Yong;Park, Bok-Hwan;Ihn, Joo-Chul
    • Journal of Yeungnam Medical Science
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    • v.5 no.1
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    • pp.43-48
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    • 1988
  • We retrospectively analysed 22 patients pelvic CT, in whom the acetabular fracture were suspected in plain film. And compared and analysed the computed tomogram findings and plain radiographic findings. The results were as follows. CT enables better evaluation of shape, extent, and degree of separation of fragment. CT was helpful in detecting the combinded fracture and soft tissue injuries. CT showed intraarticular loose bodies, which were invisible on plain film. In patients with pelvic trauma, no necessary changing position during CT examination. CT was useful demonstrates the remnant of intraarticular osseous fragment and adequacy of reduction after surgery.

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Quantitative Evaluation on Prediction of Realization by Subjects in Diagnostic Fields of Traditional Korean Medicine (한의학 진단 분야의 미래 예측 실현과제에 대한 정량적 평가)

  • Kim, Ji-Hye;Kim, Keun-Ho;Shin, Hyeun-Kyoo
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.18 no.1
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    • pp.11-24
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    • 2014
  • Objectives The aim of this study is to contribute to the establishment of the Traditional Korean Medicine (TKM) policies in future, which is through the assessment to predict the realization by diagnostic subjects. Methods First, we evaluated 8 subjects that were deduced by professionals in 1996 regarding whether or not to be realized in 2013. Second, the governmental and private research projects, reports, articles, domestic patents and products were reviewed and investigated. Third, the Subjects in domestic fields of TKM were investigated on the followings: importance, time of realization, domestic Research and Development level, principal agents and methods for the realization, and hindrance factor on the realization. Results Of the 8 forecasting subjects, one subject was realized, two subjects were partly realized and five subjects were unrealized. Thus, their realization rate was 12.5%. The realized subject is the 'Standard naming of the TKM diagnosis'. Conclusion Continuous researches are necessary to realize the TKM subjects and moreover, professionals should predict new feasible TKM subjects, based on this study.

Clinical Application of $^{18}F-FDG$ PET and PET-CT in Adrenal Tumor (부신종양에서 $^{18}F-FDG$ PET 및 PET-CT의 임상 이용)

  • Hwang, Kyung-Hoon;Choi, Duck-Joo;Lee, Min-Kyung;Choe, Won-Sick
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.sup1
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    • pp.130-133
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    • 2008
  • Adrenal tumors are increasingly detected by widespread use of anatomical imaging such as a, MRI, etc. For these adrenal tumors, differentiation between malignancy and benignancy is very important. In diagnostic assessment of adrenal tumor, $^{18}F-FDG$ PET and PET-CT have been reported to have high diagnostic performance, especially, very excellent performance in evaluation of adrenal metastasis in the oncologic patient. In cases of adrenal incidentalomas, $^{18}F-FDG$ PET or PET-CT is helpful if a or chemical-shift MRI is inconclusive. $^{18}F-FDG$ PET and PET-CT may be applied to the patients with MIBG-negative pheochromocytomas. In summary, $^{18}F-FDG$ PET and PET-CT are expected to be effective diagnostic tools in the management of adrenal tumor.

Study on Fault Diagnostics of a Turboprop Engine Using Fuzzy Logic and BBNN (퍼지와 역전파신경망 기법을 사용한 터보프롭 엔진의 진단에 관한 연구)

  • Kong, Chang-Duk;Lim, Se-Myung;Kim, Keon-Woo
    • Journal of the Korean Society of Propulsion Engineers
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    • v.15 no.2
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    • pp.1-7
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    • 2011
  • The UAV(Unmanned Aerial Vehicle) which is remotely operating with long endurance in high altitude must have a very reliable propulsion system. The precise fault diagnostic system of the turboprop engine as a propulsion system of this type UAV can promote reliability and availability. This work proposes a diagnostic method which can identify the faulted components from engine measuring parameter changes using Fuzzy Logic and quantify its faults from the identified fault pattern using Neural Network Algorithms. It is found by evaluation examples that the proposed diagnostic method can detect well not only single type faults but also multiple type faults.

Diagnostic Techniques of Lightning Arresters for DC Electric Traction Vehicles (직류전동차용 피뢰기 진단기술)

  • Kil Gyung-Suk;Song Jae-Yong;Kim Il-Kwon;Moon Seung-Bo;Shin Gwang-Chul
    • Journal of the Korean Society for Railway
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    • v.9 no.4 s.35
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    • pp.357-361
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    • 2006
  • This paper dealt with the performance evaluation and the diagnostic techniques of lightning arresters for DC electric traction vehicle. Field Measurements on the protective operation of lightning arresters against surge currents were carried out on running vehicles to acquire the data necessary for the diagnosis. The frequency and the magnitude of surge events were analyzed. Surge currents of $1\sim3$ times were recorded in one running service route and their magnitudes were ranges of $150A\sim2kA$. Also, an acceleration experiment on a lightning arrester by the standard lightning impulse current of 8/20 us and 5 kA was performed to know the aging characteristics. After the surge current application of 3,000 times, the reference voltage decreased by 4.5 %, and the leakage current was below 10 uA at the continuous operating voltage and about 50 uA at the rated voltage. From the experimental results, we propose a decision level of leakage current for the arrester used in this paper and designed an arrester tester which analyzes arrester condition by the magnitude of leakage current.

Fine Needle Aspiration Cytology of Thyroid Nodules: Assessment of diagnostic accuracy and evaluation of each cytologic diagnosis (갑상선 결절의 세침흡인 세포검사: 진단성적의 검토 및 세포학적 진단의 평가)

  • Park, In-Ae;Ham, Eui-Keun
    • The Korean Journal of Cytopathology
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    • v.10 no.1
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    • pp.43-53
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    • 1999
  • We retrospectively reviewed the results of 1,850 fine needle aspiration cytology(FNAC) of thyroid nodules performed from 1990 to 1991 in the Department of Pathology, Seoul National University Hospital. Among 1,528 cases and 322 cases aspirated by clinicians and a pathologist, 465 cases(30.4%) and 13 cases(4.0%) of the aspirates were inadequate, respectively. In 227 cases, correlation of the FNAC diagnosis and histologic diagnosis was done. Excluding the inadequate cases, the sensitivity nor the detection of neoplasm(malignancy together with follicular adenoma) was 86.4% and the specificity was 70.7%. The overall diagnostic accuracy was 79.0%. There were 16 false-positive cases(7.0%), and 19 false-negative cases(8.4%). The predictive value of each cytologic diagnosis was 92% in papillary carcinoma, and 100%, in Hashimoto's thyroiditis. The expectancy of malignancy was 52.8% in "suspicious malignancy" and 26.7% in "atypical lesion".

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Early-onset epileptic encephalopathies and the diagnostic approach to underlying causes

  • Hwang, Su-Kyeong;Kwon, Soonhak
    • Clinical and Experimental Pediatrics
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    • v.58 no.11
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    • pp.407-414
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    • 2015
  • Early-onset epileptic encephalopathies are one of the most severe early onset epilepsies that can lead to progressive psychomotor impairment. These syndromes result from identifiable primary causes, such as structural, neurodegenerative, metabolic, or genetic defects, and an increasing number of novel genetic causes continue to be uncovered. A typical diagnostic approach includes documentation of anamnesis, determination of seizure semiology, electroencephalography, and neuroimaging. If primary biochemical investigations exclude precipitating conditions, a trial with the administration of a vitaminic compound (pyridoxine, pyridoxal-5-phosphate, or folinic acid) can then be initiated regardless of presumptive seizure causes. Patients with unclear etiologies should be considered for a further workup, which should include an evaluation for inherited metabolic defects and genetic analyses. Targeted next-generation sequencing panels showed a high diagnostic yield in patients with epileptic encephalopathy. Mutations associated with the emergence of epileptic encephalopathies can be identified in a targeted fashion by sequencing the most likely candidate genes. Next-generation sequencing technologies offer hope to a large number of patients with cryptogenic encephalopathies and will eventually lead to new therapeutic strategies and more favorable long-term outcomes.

The Technological Concept of Fibroscan and its Clinical Usefulness in the Traditional Korean Medical Field (비침습적 간섬유화 측정기(Fibroscan)의 기술적 개요와 한의임상적 유용성 고찰)

  • Son, Chang-gue
    • The Journal of Internal Korean Medicine
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    • v.36 no.2
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    • pp.85-92
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    • 2015
  • Objectives: The liver fibroscan has been developed as a noninvasive and convenient method to assess hepatic fibrosis. This study aimed to review this device in terms of its technological concept and clinical application in traditional Korean medicine (TKM). Methods: The technological background, diagnostic evaluation, and clinical usefulness of fibroscan were reviewed using various literature and clinical studies. One clinical example-a patient with hepatofibrosis who had been treated with TKM-is presented. Results: The liver fibroscan was approved as a medical device for noninvasive measurement of the hepatic fibrosis level by the Korean Food and Drug Administration (KFDA). Numerous clinical studies have confirmed that its sensitivity and specificity allow it to serve as a substitute for liver biopsy, the present gold standard diagnostic method. The accuracy and reproducibility and lack of technical risks are strong points of the fibroscan; however, it has some limitations for application, especially in patients with obesity or severe hepatitis. One clinical example showed the applicability of the liver fibroscan in herbal medicine-based treatments. Conclusions: The requirement for diagnostic medical devices is an important issue in TKM; therefore, this study provides valuable information for practitioners of TKM.