• Asian Pacific Journal of Cancer Prevention
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• 제17권9호
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• pp.4357-4361
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• 2016

Background: Whether there is any relationship between human papilloma virus (HPV) and breast carcinoma is not clear. Some previous studies have indicated a possible role in oncogenesis in the breast. In this study, we therefore analyzed the presence of HPV infection in breast tissues of Iranian women from Yazd city. Materials and Methods: In a cross-sectional study, formalin-fixed paraffin-embedded tissues from 87 patients with breast cancer and 84 cases with breast fibrocystic lesions (control group) were selected from a tissue archive. Grade of tumors and fibrocystic tissues were determined by two pathologists. The nested-PCR method was performed for detection of HPVs in samples. HPV genotypes were determined by sequencing and the phylogenetic tree depicted by MEGA software. Results: Of the 87 women with breast cancer, 22.9% (20 isolates) had positive results for HPV DNA. In the control group no HPV was detected. The HPV genotypes in positive samples were HPV-16 (35%) HPV-18 (15%), HPV-6 (45%) and HPV-11 (5%). The data did not approved a significant correlation between tissue pathology of breast cancer and the HPV genotype frequency. Conclusions: The data did not provide any evidence for a role of high risk HPV types in oncogenesis in the breast.

• 사상체질의학회지
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• 제22권3호
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• pp.98-109
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• 2010

1. Objectives: This study is to investigate the association of Sasang Constitution and chronic obstructive pulmonary disease(COPD). 2. Methods: One thousand five hundred forty five persons, more than 40 years old, participated in the community based cohort in Wonju City and Pyeongchang City of South Korea from October 29th in 2007 to February 26th in 2008. The diagnosis of COPD was confirmed by spirometry and based on the diagnostic criteria developed by GOLD (Global Initiative for Chronic Obstructive Lung Disease) standard. Relating items like height, weight, BMI(Body Mass Index), martial status, income, drinking, smoking and education were checked using questionnaires and Sasang Constitution was diagnosed by a specialist using PSSC(Phonetic System for Sasang Constitution), facial photos and check-up lists. 3. Results: There were 88 persons(5.7%) who had mild COPD. Old age(more than 60's) and male were significant risk factors of COPD. But smoking, drinking and Sasang Constitution were not risk factors of COPD. But there were many Soeumin who had mild COPD in terms of Sasang Constitution irrespective of sex. 4. Conclusions: Low BMI(<23kg/m2) and low income also were significant risk factors. And Sasang Constitution might be the variable to manage COPD patients, but more researches are needed.

• 사상체질의학회지
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• 제23권2호
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• pp.218-229
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• 2011

1. Objectives: This study is to investigate the relationship between Intima Media Thickness(IMT) of common carotid artery and Sasang Constitution. 2. Methods: 839 persons, over 40 years old, participated in community-based cohort of Korea Genome and Epiedemiology Study (KOGES) in Wonju City and Pyeongchang City of South Korea from June 2006 to February 2008. The diagnosis of Common carotid Intima Media Thickness was evaluated by B Mode ultrasonography, cardiovascular risk factors were checked using questionnaire and blood samples. Constitution was verified by a Sasang constitution specialist according to the results of PSSC(Phonetic System for Sasang Constitution), facial photos and a simplified Sasang constitutional questionnaire. Multiple regression analysis and logistic regression analysis were performed with SPSS. 3. Results: There were significantly high values in waist circumference, fasting blood sugar, systolic blood pressure, diastolic blood pressure, triglyceride, HOMA-IR and hsCRP in Taeeumin and low in HDL-cholesterol and adiponectin in Taeeumin. There were significantly high value in Common Carotid Intima Media Thickness in Taeeumin. Age was the significant cardiovascular risk factor irrespective of Sasang constitution in all participants. There was a positive correlation between smoking and Soyangin in all participants and men. There were positive correlations between LDL-cholesterol, BMI and Taeeumin in all participants and men. There were positive correlations between hsCRP and Soeumin in all participants and men. There was significantly high odds ratio of Taeeumin over Soeumin in common carotid Intima Media Thickness. 4. Conclusions: Regimens on cardiovascular diseases should be considered according to Sasang constitution. There are more sensitive risk factor in each constitution; smoking in Soyangin, LDL-cholesterol and BMI in Taeeumin, hsCRP in Soeumin.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제17권2호
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• pp.61-73
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• 2014

Presented are guidelines for the prevention, diagnosis, and treatment of cow's milk protein allergy (CMPA) which is the most common food allergy in infants. It manifests through a variety of symptoms that place a burden on both the infant and their caregivers. The guidelines were formulated by evaluation of existing evidence-based guidelines, literature evidence and expert clinical experience. The guidelines set out practical recommendations and include algorithms for the prevention and treatment of CMPA. For infants at risk of allergy, appropriate prevention diets are suggested. Breastfeeding is the best method for prevention; however, a partially hydrolyzed formula should be used in infants unable to be breastfed. In infants with suspected CMPA, guidelines are presented for the appropriate diagnostic workup and subsequent appropriate elimination diet for treatment. Exclusive breastfeeding and maternal dietary allergen avoidance are the best treatment. In infants not exclusively breastfed, an extensively hydrolyzed formula should be used with amino acid formula recommended if the symptoms are life-threatening or do not resolve after extensively hydrolyzed formula. Adherence to these guidelines should assist healthcare practitioners in optimizing their approach to the management of CMPA and decrease the burden on infants and their caregivers.

• 한국산업보건학회지
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• 제15권2호
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• pp.114-123
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• 2005

We analyzed the demographic and job features of 197 shipyard workers with work-related musculoskeletal disorders(WMSDs) compensated by the Industrial Accident Compensation Insurance Act, and the features of the disorders, the causes of operation and the induced behaviors. The three shipbuilding companies surveyed were located in Busan Metropolitan city and Gyungsangnam-do. The results were as follows. 1. The ages of WMSDs patients in shipyard were $43.6{\pm}8.6$ and the job tenure was $14.3{\pm}5.6$. The 40's of them was 40.1%, and the 30's was 29.4%. Patients less than 5 year-work duration were 85.3%, and ones more than 16 year-work duration 6.6%. In occupations, welders were 32.5%, pre-welders 17.3%, and setting engineers 6.6%. 2. The causes of WMSDs in shipyard were works(95.4%) and outer crash or accident shock (3.6%). Based on the standard of the NIOSH induced behaviors, the causes were awkward posture (62.9%), excessive movement(19.3%) and repetitive movement(13.7%). 3. The compensated WMSDs by body part was the highest, 36%, in the spines, 32.0% in both the upper limbs and the spines, and 14% in the upper limbs. The number of cases of WMSDs in body were 96 in the cervical, 79 in the lumbar and 72 in the shoulders. 4. As a result of chi-square test(${\chi}^2$) between diagnosis and operation in body, welding and spot welding had the most diagnoses in all parts of the body among other occupations. Chi-square test(${\chi}^2$) between diagnosis and induced behavior in body showed that awkward postures recorded the highest rate and repetitive movements was the second. 5. The most hazardous occupation was the welding(incidence rate=9.7) and the most hazardous behavior was the awkward posture.

• 한국산업보건학회지
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• 제25권4호
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• pp.446-464
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• 2015

Objectives: This study was conducted to evaluate the task-specific hazards of chemicals used by nail technicians in Daegu Metropolitan City. Materials: A total of 30 nail shops located in Daegu City were surveyed to investigate the major tasks and practices performed by nail technicians and the ingredients listed in nail care products used in shops. We also collected instructions for use and material safety data sheets(MSDSs) of nail care products and compared CAS Nos. of ingredients with the lists of chemicals regulated by the Industrial Safety and Health Act(ISHA) and Chemical Substances Control Act(CSCA). Results: A total of 125 chemical ingredients were found in 468 nail care products used at the 30 nail shops. The most frequently found ingredients were ethyl acetate(72%), followed by n-butyl acetate(71.8%), isopropanol(56%), benzophenone(51.1%), nitrocellulose(46.4%) and ethanol(45.3%). Comparing six tasks, the task of manicuring used the most products at 222 products containing 91 ingredients. Among the 125 ingredients, there are 31 chemicals with occupational exposure limits(OEL) designated by the Ministry of Employment and Labor(MoEL), eight categorized as carcinogens, one mutagen and two reproductive toxic chemicals. In terms of carcinogens, formaldehyde was identified as the only confirmed human carcinogen(1A). We found that there was one chemical with a permissible limit, one special management substance, 18 workplace monitoring substances and ten special health diagnosis substances regulated by ISHA. For CSCA, nine poisonous substances, six substances requiring preparation for accidents and one restricted substance were identified. Conclusions: Based on these findings, formaldehyde was identified as one of the chemicals that should most strictly be controlled for the protection of the health of nail technicians and customers. At the same time, it is necessary to distribute materials with detailed hazardous information of nail care products for nail shop technicians.

• Allergy, Asthma & Respiratory Disease
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• 제6권6호
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• pp.303-309
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• 2018

Purpose: Foreign body aspiration in children is emergent and can cause serious complications. This study aims to show the clinical characteristics of foreign body aspiration and to analyze the clinical cases of delayed diagnosis to predict and prevent complications. Methods: We retrospectively reviewed the medical records of 63 children (48 in Inha University Hospital and 15 in Gachon University Gil Medical Center) who were diagnosed with foreign body aspiration through bronchoscopy from 1996 to 2017 in Incheon City, and analyzed clinical characteristics. Patients were divided into 3 groups: those were diagnosed within 24 hours, delayed after 24 hours, or delayed more than 7 days according to time elapse from the time of foreign body aspiration, and clinical characteristics of each group were compared. Results: Aspiration occurred in 58.7% at 1 year and 15.9% at 2 years. Cough (65.1%) and coarse breathing sound (41.3%) were most common, and radiologic findings were commonly presented as emphysema on the affected side (41.3%). Nuts were most common (42.9%), and there was no difference in the frequency between the right and left main bronchi. The documented history of foreign body aspiration was more frequently found in the early diagnosed group; however, sputum, fever, and complications were more frequent in the delayed diagnosed group. Conclusion: If a patient with respiratory disease has persistent fever or sputum, foreign body aspiration should be suspected.

• 한국환경보건학회지
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• 제40권5호
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• pp.367-375
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• 2014

Objectives: The main purpose of this study is to produce background data which can be compared with several large-scale industrial complex regions. Methods: The framework of this study was designed to evaluate and monitor health effects associated with low-level and long-term exposure to environmental pollutants. In this study, 1,009 local residents were recruited in the city of Chungju using personal questionnaires, medical check-ups, and allergen skin-prick tests for 12 common allergens. The prevalence rate of skin allergens was reviewed together with that from large-scale industrial areas. Results: The diagnosis prevalence and medical treatment prevalence of asthma was 5.6% and 1.7%, respectively. Allergic rhinitis was 25.4% and 16.7%, allergic dermatitis was 16.6% and 9.9% and allergic conjunctivitis was 18.7% and 7.9%, respectively. These results were similar with those of industrial complexes. The prevalence of allergen skin-prick test was 16.4% and the most common allergen was dust mites (27.9-31.6%). This result was lower than those of the industrial complexes (22.5-39.9%) and Gangneung (18.2-24.7%). Conclusion: Further study is required to find the cause of the regional differences in skin prick prevalence.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2009년도 추계학술대회
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• pp.499-502
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• 2009

전체 시스템과 네트워크에 대한 전력의 공급과 전기안전은 필수적인 요소이다. 전기안전기술은 u-IT 기술의 발전과 함께 융복합화된 제품개발이 이루어지면서 제품에 대한 평가와 인증에 관한 연구가 필요하다. 본 논문에서는 전력기기와 u-IT기기의 융복합화 제품을 u-City에 적용시킬 전기안전 통합감시시스템을 개발하기위해, 전력기기 단말에서 가장 많이 사용되는 아울렛에서 접속불량 검출장치가 내장된 전력 IT 융복합화 기기를 만들었다. 전기안전 통합감시시스템에서의 원격 안전 점검을 위한 ZigBee, RFID의 센서를 이용하여 통신과 모듈의 성능 평가를 하고, PD, Arc 검출 진단 시스템에서 성능 실험 및 평가를 하여 적합 판정을 받은 제품에 대하여 KS, 전기안전 인증을 한다.

• 동의신경정신과학회지
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• 제8권1호
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• pp.151-165
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• 1997

The primary purpose of this study was to assess the relation of stress perception and poststroke. This study was done on 50 stroke patients in hospital. According to activities of functional impairment, they were classified into walking disturbance, motor weakness, dysphagia, or reattack etc. The stress perception test(GARS Scles) and stress response assessment shows the follwing results. 1. On the distribution in the stroke 50 patients, For the majority group were male in sex, sixty inage, middle towns people in residence. 2. On the comprehensive GARS scale scores, It marked the higest scores thirty at age, merchandise or salesman on jobs, a city in residence. There was no signigicant difference in mean GARS Scales scores between males and females group, the left hemiplegia and the Rt hemiplegia. 3. On the comprehensive GARS Scale tests, Overall glogal stressor(G8) and sickness stresor(G4) marked the highest scores of all GARS Scales. 4. On the comparative assessment of each group's stress reponse test scores, zung-bu(中腑) was showed higher scores than the other group in oriental diagnosis and hemorrage was showed higher scores than the other group in western medical diagnosis. 5. On the comprehensive assessment of each group's stress reponse test scores, aphsia(不語) marked the highest scores in another disphagia group's. It marked the highest scores in another group's that banshinbulsoo(半身不遂) as regards as hemiplegia generally. Standing disability is the higher scores than another group's walking alone or assist, and standing alone. 6. Secondary attack is the highest scores of all reattack stroke on the stress repones test. 7. Comparing and analyzing the GARS Scale total scores and GARS Scale subject fator at stroke, we found that sickness stressor and fininial stressor is showed the highest correlated to stress response fowlloing stroke. With those results, we can see that functional impairment following stroke is correlated to stress perception and reponse. In the furture studies using, we hope that the findings the study would have clinical relevance to the psychosocial adjustment and total rehabilation of stroke patients.