• Biomolecules & Therapeutics
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• v.29 no.1
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• pp.1-10
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• 2021

COVID-19 has caused extensive human casualties with significant economic impacts around the globe, and has imposed new challenges on health systems worldwide. Over the past decade, SARS, Ebola, and Zika also led to significant concerns among the scientific community. Interestingly, the SARS and Zika epidemics ended before vaccine development; however, the scholarly community and the pharmaceutical companies responded very quickly at that time. Similarly, when the genetic sequence of SARS-CoV-2 was revealed, global vaccine companies and scientists have stepped forward to develop a vaccine, triggering a race toward vaccine development that the whole world is relying on. Similarly, an effective and safe vaccine could play a pivotal role in eradicating COVID-19. However, few important questions regarding SARS-CoV-2 vaccine development are explored in this review.

• Journal of applied mathematics & informatics
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• v.41 no.1
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• pp.215-228
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• 2023

The ready-made garments (RMG) have been making a crucial contribution about of 81% of total export and 12.36 % of total GDP of the country which is now the single biggest export earner for Bangladesh. The cheap production cost is the key important factor to explore this RMG sector. But these RMG sector is running on the basis of intuition based decisions. Though they are making profit it is not optimal. In this study, a deterministic model is developed to help the RMG to minimize the production cost and to maximize their profit along with optimal utilization of available resources. 10 different types of products are taken from one of the garments factories of Gazipur, Dhaka to prepare this research work. This model suggests the manufacturer on which products along with how much should be produced to meet the future demand by maintaining the lowest production cost that ultimately maximize the profit of the organization, and also helps Bangladesh to compete in the international market with 'Made in Bangladesh'. LINDO programming is used here to solve this LP model.

• Asia pacific journal of information systems
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• v.32 no.4
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• pp.857-889
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• 2022

Home theft and burglary are prevalent in Dhaka city. Internet of things (IoT), in contrast, is commonly recognized as among the most advanced home security systems. However, the factors that attract young people to use IoT for household security have yet to be examined. Consequently, the purpose of this article is to validate the attitude-social influence-self-efficacy (ASE) model with personal innovativeness and perceived trust. We collected data from Dhaka citizens aged 15 to 24 using a purposive sample technique and 370 valid responses were chosen for the study. According to the analysis, all of our proposed hypotheses were found significant with a 73.6% variance. Furthermore, the effects of attitude and social influence were shown to be the highest and lowest, respectively, and trust and innovativeness were both nearly strong main predictors of ASE. Significantly, since this is one of the few studies in the technology adoption domain using this model, a solid foundation for IoT adoption for security purposes is established.

• Bulletin of the Korean Chemical Society
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• v.31 no.4
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• pp.1088-1090
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• 2010

• Interdisciplinary Bio Central
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• v.4 no.1
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• pp.1.1-1.7
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• 2012

Background: The F-box proteins represent one of the largest families of proteins in eukaryotes. Apart from being a component of the ubiquitin (Ub)/26 S proteasome pathways, their regulatory roles in other cellular and developmental pathways have also been reported. One interesting feature of the genes encoding the proteins of this particular family is their variable selection patterns across different lineages. This resulted in the presence of lineage specific F-box proteins across different species. Findings: In this study, 48 non-redundant F-box proteins in E. siliculosus have been identified by a homology based approach and classified into three classes based on their variable C-terminal domains. A greater number of the F-box proteins have domains similar to the ones identified in other species. On the other hand, when the proteins having unknown or no C-terminal domain (as predicted by InterProScan) were analyzed, it was found that some of them have the polyglutamine repeats. To gain evolutionary insights on the genes encoding the F-box proteins, their selection patterns were analyzed and a strong positive selection was observed which indicated the adaptation potential of the members of this family. Moreover, four lineage specific F-box genes were found in E. siliculosus with no identified homolog in any other species. Conclusions: This study describes a genome wide in silico analysis of the F-box proteins in E. siliculosus which sheds light on their evolutionary patterns. The results presented in this study provide a strong foundation to select candidate sequences for future functional analysis.

• BMB Reports
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• v.38 no.6
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• pp.661-667
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• 2005

Since conflicting results have been reported on non-specific immune response in type 1 diabetes, this study evaluates polymorphonuclear neutrophil (PMN) functions in the infection free Long Evan diabetic rats (type 1) by using tests that include: polarization assay, phagocytosis of baker's yeasts (Saccharomyces cerevisiae) and nitroblue tetrazolium (NBT) dye reduction. Polarization assay showed that neutrophils from diabetic rats were significantly activated at the basal level compared to those from the controls (p < 0.001). After PMN activation with N-formyl-methionyl-leucyl-phenylalanine (FMLP), control neutrophils were found to be more polarized than those of the diabetic neutrophils and the highest proportions of polarization were found to be 67% and 57% at $10^{-7}\;M$ FMLP, respectively. In the resting state, neutrophils from the diabetic rats reduced significantly more NBT dye than that of the controls (p < 0.001). The percentages of phagocytosis of opsonized yeast cells by the neutrophils from control and diabetic rats were 87% and 61%, respectively and the difference was statistically significant (p < 0.001). Evaluation of the phagocytic efficiency of PMNs revealed that control neutrophils could phagocytose $381{\pm}17$ whereas those from the diabetic rats phagocytosed $282{\pm}16$ yeast cells, and the efficiency of phagocytosis varied significantly (p < 0.001). Further, both the percentages of phagocytosis and the efficiency of phagocytosis by the diabetic neutrophils were inversely related with the levels of their corresponding plasma glucose (p = 0.02; r = -0.498 and p < 0.05; r = -0.43, respectively), which indicated that increased plasma glucose reduced the phagocytic ability of neutrophils. Such relationship was not observed with the control neutrophils. These data clearly indicate that PMN functions are altered in the streptozotocin (STZ) - induced diabetic rats, and hyperglycemia may be the cause for the impairment of their functions leading to many infectious episodes.

• Women's Health Nursing
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• v.24 no.1
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• pp.49-57
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• 2018

Purpose: Postpartum fatigue can impact maternal well-being and has been associated with levels of perceived self-care. This study aimed to examine the relationship among fatigue, depressive mood, self-care agency, and self-care action among postpartum women in Bangladesh. Methods: A descriptive cross sectional survey was done with 124 first-time mothers from two tertiary hospitals in Dhaka, Bangladesh. The Modified Fatigue Symptoms checklist, Denyes' Self Care Instrument, the Edinburgh Postnatal Depression Scale, and items on sociodemographic and delivery-related characteristics, were used in Bengali via translation and back-translation process. Results: High fatigue levels were found in 18.5% (n=23) and 73.4% had possible depression (n=91). There was a significant negative relationship between fatigue and self-care agency (r=-.31, p<.001), and self-care action (r=-.21, p<.05). Fatigue differed by level of self-care agency (t=4.06, p<.001), self-care action (t=2.36, p=.023), newborn's APGAR score (t=-2.93, p=.004), parental preparation class participation (F=15.53, p<.001), and postpartum depressive mood (t=-4.64, p<.001). Conclusion: Findings suggest that high level of self-care efficacy and behaviors can contribute to fatigue management, and highlight the need for practical interventions to better prepare mothers for postpartum self-care, which may, in turn, alleviate postpartum fatigue.

• Journal of Information Science Theory and Practice
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• v.10 no.4
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• pp.66-86
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• 2022

The main aim of this study is to identify the role of information dissemination on urban and rural citizens of Bangladesh during the COVID-19 pandemic and the role of misinformation in this process. The study also aimed at finding appropriate counter misinformation strategies regarding COVID-19. An online questionnaire was prepared to collect the viewpoints of the urban and rural citizens of Bangladesh regarding dissemination of information during COVID-19, misinformation regarding COVID-19, and counter misinformation strategies. Along with demographic and general information, a five-point Likert scale was used to measure COVID-19 related misinformation beliefs and how to counter them. Chi square tests were used to determine the association between current residency, information sources, the importance of information dissemination, reactions after getting COVID related information, and evaluative steps after getting information and before disseminating it. Additionally, nonparametric Mann-Whitney U and Kruskal-Wallis tests were conducted to know the significance of difference in respondents' assessment on COVID-19 related misinformation in terms of their demographic characteristics. Cronbach's alpha score was obtained to see the reliability of the questionnaire items. The current study reveals that both urban and rural citizens of Bangladesh are influenced by information dissemination regarding COVID-19 and they have lower level of misinformation belief. The respondents have differences in misinformation belief by different demographic groups. Respondents' educational status, information literacy, sources of getting information, and evaluative steps after getting information have significant differences in misinformation belief. The study also noticed the support of respondents for countering misinformation strategies regarding COVID-19.

• Nuclear Engineering and Technology
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• v.55 no.12
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• pp.4617-4627
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• 2023

Public perception of benefit over risk is the de facto factor in planning, construction, operation, halting, or phase-out of a nuclear power plant in any country. Even if there are multiple pathways of perceiving risk/benefit among different stakeholders, the perception of nuclear and non-nuclear groups needs to be individually tracked to help understand sectoral influence. Related studies were basically performed between the STEM (Science, Technology, Engineering, and Mathematics) and non-STEM groups. However, there are no such studies between the nuclear and non-nuclear groups. This study investigated the risk-benefit perceptions between the nuclear group (N = 102) and the non-nuclear group (N = 467) using survey data to measure their stake and identify the underlying factors by validating the hypotheses, through descriptive analysis, and structural equation modeling (SEM). Results showed that risk perception is significantly high in the non-nuclear group (as the P-value is > 0.001 to <0.01) while the benefit perception is slightly low in the nuclear group (as the P-value is > 0.01 to <0.05). The non-nuclear group was significantly influenced by risk perception due to a lack of involvement in nuclear activities. Notably, the nuclear group is less interactive in disseminating nuclear energy benefits to the non-nuclear group. Surprisingly, misperceptions and lack of confidence about the benefits of nuclear energy also exist in the nuclear group. The study emphasizes debunking nuclear myths in the nuclear and non-nuclear groups through meaningful interactions and demands effective public awareness-building programs by competent authorities for the growth of the nuclear industry.

• Asian-Australasian Journal of Animal Sciences
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• v.6 no.3
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• pp.423-426
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• 1993

A total 930 outbreaks of Foot and Mouth Disease (FMD) were recorded in Bangladesh from 1988 to 1991. Number of FMD outbreaks was recorded highest in Rajshahi division (304) followed by Dhaka (272), Khulna (203) and Chittagong (151). During 1988 to 1991, FMD outbreaks reached in peak level in 1990 (540) followed by 1989 (209), 1988 (95) and 1991 (86). Outbreaks though occurred throughout the year were higher in premonsoon and winter seasons. Morbidity rate was found significantly higher (p<0.01) in cattle (35.5%) than buffaloes (23.3%) and sheep/goats (4.8%). Of the cattle, bull/bullock infected more (p<0.01) than cows and calves. Morbidity rate in different animals was observed significantly higher (p<0.01) in Rajshahi and Dhaka divisions than in Khulna and Chittagong. Mortality specially in calves was found at the rate of 50.9%. Loss in milk yield was found to be 66.6%. Disease period for a FMD affected cattle varied from 16 to 26 days (average 22.7 days). Loss of working days per working cattle ranged from 14 to 24 days (average 21.2 days) and the loss in draft energy per cattle was found to be 12.7 to 18.9 KW hour.