• 대한감각통합치료학회지
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• 제12권2호
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• pp.1-12
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• 2014

목적: 자폐스펙트럼장애 아동의 감각처리유형, 청각행동특성, 사회성과의 관계를 살펴보고자 하였다. 연구방법 : 연구대상은 만 2~14세까지의 자폐스펙트럼장애로 진단 받거나 의심되는 아동 26명을 대상으로 2014년 5월부터 6월까지 실험하였다. 검사도구는 감각력검사, 청각행동특성검사, 이화자폐아동 행동발달평가검사, 사회성숙도검사, 학교기능검사를 사용하였고, 자료분석은 SPSS 18.0을 사용하였다. 결과 : 첫째, 감각처리는 청각행동특성에서 학령전 아동은 배경소음속듣기와 학령기 아동은 의사소통과 통계적으로 유의미 했다. 둘째, 배경소음속듣기와 의사소통은 아동의 사회성과 관련이 있었다. 결론 : 작업치료사는 자폐스펙트럼장애 아동의 사회성을 향상시키기 위해 감각통합치료를 지속적으로 적용, 확대하는 것이 필요하다.

• 한국실내디자인학회논문집
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• 제20권4호
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• pp.136-144
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• 2011

The purpose of this research is to analyze the manifestation of children's color education in the software in order to evaluate conditions of color education as well as improvement of its direction. The procedure and method of the research is begun from evaluating the characteristic of children's developmental stage, content analysis of the nation's organization of color education and analysis and evaluation of education program through the investigation on 8 different softwares in reward for the tournament. The results are as followings; First, the research shows that the elementary school stage of color education is inadequate in comparison to children's cognitive developmental stage. Second, most of the color theory was composed of characteristic of a color, stimulation of emotion and effects of psychology. Considering of children's cognitive development, it is necessary to make up for the basic of color theory and the system of color. Third, Softwares of color education program for 1 st. and 2nd grade in elementary school was so rare that it should be properly developed and made for systematic contents. Fourth, color education for the 5th and 6th grade children remained in understanding basic characteristics of the color which is below the par and brings the necessity for more professional and structural contents.

• Asian-Australasian Journal of Animal Sciences
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• 제21권3호
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• pp.340-345
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• 2008

Oxidative stress is one of the major causes of failure of in vitro storage of boar semen. Reactive oxygen species (ROS) are one of the important mediators of oxidative stress during in vitro storage of boar semen. Our study examined the effects of taurine on sperm characteristic and on in vitro developmental embryos during in vitro storage of boar semen for 7 days. Semen was randomly aliquoted into 3 centrifuge tubes and treated with different concentrations of taurine (25-100 mM). The characteristics of boar sperm were analyzed for motility by light microscopy, viability by using a Makler counting chamber and membrane integrity by a hypoosmotic swelling test (HOST). The percentages of motile spermatozoa in taurine groups after 5 days were significantly higher compared to the control. Sperm viability in the control was lower than in taurine groups after 7 days irrespective of different taurine concentration. In the hyoosmotic swelling test (HOST), significantly higher results were obtained in taurine groups after 3 days. Also, the developmental rates of IVM/IVF porcine embryos from semen treated with pyruvate and taurine were significantly increased when compared with the control (p<0.05). These results indicate that supplementation of taurine as an antioxidant in boar semen extender can improve the semen quality.

• Journal of Genetic Medicine
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• 제16권2호
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• pp.49-54
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• 2019

Purpose: Potocki-Lupski syndrome (PTLS), is a recently identified, rare genomic disorder. The patients are affected by infantile hypotonia, poor growth and developmental delay. Facial dysmorphism may not be obvious in some patients. PTLS is associated with microduplication at chromosome 17p11.2. In the current study, three Korean patients are reported with their clinical and genetic features. Materials and Methods: The clinical findings of each patient were reviewed. Karyotyping and multiplex ligation-dependent probe amplification (MLPA) analyses were done for genetic diagnoses. Results: All the patients did not have the characteristic dysmorphic features, such as broad forehead, triangular face, asymmetric smile and palpebral fissures. On the other hand, all three patients were affected by variable degree of developmental delay, poor oral intake, failure to thrive, and language development disorders. Chromosome 17p11.2 duplication was identified by conventional karyotyping analysis only in one patient, whereas the other confirmed by MLPA analyses. Conclusion: Delayed development was mostly commonly observed in our patients without distinct dysmorphic facial features. In this respect, genomic screening in patients with developmental delay would identify more cases with PTLS to understand their long-term clinical courses with the development of adequate psychological and rehabilitation education program.

• 동서간호학연구지
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• 제22권1호
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• pp.1-9
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• 2016

Purpose: We conducted a literature review for analyzing the effect of massage on children according to their developmental stage in Korea. Methods: Various academic databases were utilized for a bibliographic search, and the keyword, 'massage', was used to identify relevant references without limits on years to determine the overall research trends. Finally, 38 references cited from 1998 to 2014 were selected in Korea. Results: Only two studies adapted a randomized controlled trial design. With regard to children's developmental stage, half studies were conducted for neonates. Moreover, the percentage of application of a sensory stimulation protocol in newborn infants was 47.3%. Eighty four point one percent of studies measured physiological characteristics as outcome variables and the rate of growth was the most common (46.5%) physiological characteristic. On the contrary, only one study (4%) was conducted to evaluate the effect of massage on psychological characteristics in school aged and the adolescents. Conclusion: This study provides fundamental data on the development and direction for future studies by analyzing studies on pediatric massage in Korea.

• Journal of Ecology and Environment
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• 제35권3호
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• pp.195-201
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• 2012

Seasonal variations in the profile and concentrations of essential oil in Zanthoxylum piperitum were investigated by gas chromatography-mass spectrometry. Seasonal changes in the percentages of the main constituents of the essential oil of both leaves and fruits from Z. piperitum varied. Variations in essential oil yield and the amount of monoterpenes and sesquiterpenes in leaves and fruits at different developmental stages were significant. The characteristic content of essential oil in leaves was determined mainly due to the content of monoterpenes, and that in fruits was determined largely due to the sesquiterpenes. Twenty-nine compounds in the oil from Z. piperitum leaves were detected; the major compounds were ${\beta}$-phellandrene (26.90%), citronella (15.32%), ${\beta}$-myrcene (3.24%), ${\alpha}$-pinene (2.79%), trans-caryophyllene (2.66%), and fanesyl acetate (2.30%). The highest yield of oil (43.89%) in Z. piperitum leaves was obtained in May but decreased gradually beginning in June. The yield of essential oil from Z. piperitum leaves during early periods was higher than that during later periods and usually decreased from early maturation stages to subsequent stages. However, in contrast to leaves, the oil yield in Z. piperitum fruit increased in June, and oil yield later in the season was higher than that earlier in the season. These results indicate that the essential oil produced from Z. piperitum leaves at the early developmental stages was stored in leaves, and might be transferred to fruit at the final developmental stages.

• 한국잠사학회:학술대회논문집
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• 한국잠사학회 2003년도 International Symposium of Silkworm/Insect Biotechnology and Annual Meeting of Korea Society of Sericultural Science
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• pp.120-122
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• 2003

It was investigated whether developmental characteristic of foundation queens of Bombus ignitus collected in the 11 localities including Jeongsun have any effects by the first oviposition days. Materials and Methods: materials - insect : foundation queens of Bombus ignitus collected in the 11 localities. Methods - we investigated the rate of colony foundation, progeny-queen production and the number of adults emergence for the relationship between first oviposition day and colony development of B. ignitus (omitted)

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 1998년도 제4차 학술발표대회 및 정기총회
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• pp.57-58
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• 1998

From the present study, following conclusions can be drawn: 1. lide in other species, axolotl FGF-8 is proposed to play a similar role in the early phase of limb development. However, the mechanism of its expression might be somewhat different from amniotes considering its characteristic mesenchymal expression. 2. In the regenerating axolotl limbs, Fgf-8 expression profile suggests that it is involved in wound gealing, dedifferentiation, and blastema formation. 3. Exoggenously supplied FGF-8 can accelerate blastema formation and concomitantly increase the Msx-1 expression level at the early stage of limb regeneration. Furthermore, it can partially substitute for nerve factor(s) as has been indicated by the induction of blastema formation in the denervated regenerates after FGF-8 application. 4. The unique expression feature of Fgf-8 in hte mesenechymal tissue of the regenerating axolotl limb might be casually related to its remarkable regeneration capacity of urodele.

• Journal of Genetic Medicine
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• 제18권2호
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• pp.75-82
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• 2021

Speech and language functions are highly cognitive and human-specific features. The underlying causes of normal speech and language function are believed to reside in the human brain. Developmental persistent stuttering, a speech and language disorder, has been regarded as the most challenging disorder in determining genetic causes because of the high percentage of spontaneous recovery in stutters. This mysterious characteristic hinders speech pathologists from discriminating recovered stutters from completely normal individuals. Over the last several decades, several genetic approaches have been used to identify the genetic causes of stuttering, and remarkable progress has been made in genome-wide linkage analysis followed by gene sequencing. So far, four genes, namely GNPTAB, GNPTG, NAGPA, and AP4E1, are known to cause stuttering. Furthermore, thegeneration of mouse models of stuttering and morphometry analysis has created new ways for researchers to identify brain regions that participate in human speech function and to understand the neuropathology of stuttering. In this review, we aimed to investigate previous progress, challenges, and future perspectives in understanding the genetics and neuropathology underlying persistent developmental stuttering.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제26권1호
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• pp.30-37
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• 2015

Objectives: The purpose of this study was to verify the validity and clinical cutoff score of the Child Behavior Checklist for ages 1.5-5 (CBCL 1.5-5) for diagnosis of autism spectrum disorder (ASD). Methods: 44 ASD infants and 100 normal infants participated. T-test, discriminant analysis, receiver operating characteristic (ROC) curve analysis, and odds ratio analysis were performed on the data. Results: Discriminant validity was confirmed by mean differences and discriminant analysis on the subscales of Withdrawn, Attention problems, Internalizing problems, Externalizing problems, Total problems, and all Diagnostic and Statistical Manual of Mental Disorders (DSM)-oriented scales between the two groups. ROC curve analysis showed that Withdrawn, Attention problems, Internalizing problems, Externalizing problems, Total problems, DSM pervasive developmental problems, DSM attention deficit/hyperactivity problems, and DSM oppositional defiant problems significantly predicted ASD infants compared to normal infants. In addition, the clinical cutoff score criteria adopted in the Korean CBCL 1.5-5 for subscales of Withdrawn, Attention problems, Internalizing problems, Externalizing problems, Total problems, DSM pervasive developmental problems, DSM attention deficit/hyperactivity problems, and DSM oppositional defiant problems were shown to be valid. Conclusion: The subscales of Withdrawn, Attention problems, Internalizing problems, Externalizing problems, Total problems, DSM pervasive developmental problems, DSM attention deficit/hyperactivity problems, and DSM oppositional defiant problems significantly discriminated for the diagnosis of ASD.