• Proceedings of the Korean Society of Developmental Biology Conference
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• 2004.07a
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• pp.34-35
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• 2004

• Journal of Embryo Transfer
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• v.33 no.1
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• pp.31-40
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• 2018

Developmental aspects of chicken embryos showed dramatic difference compared with those of mammals and consequently, such difference in various developmental events leads to different feasibility in both clinical and industrial application. We have concentrated on the studies for using of chicken bone marrow cells and currently we found number of unique cellular properties. Through this article, we reviewed characteristics and cell signaling of osteogenic cells during endochondral ossification in chicken long bone.

• Journal of Korean Academy of Nursing
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• v.30 no.5
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• pp.1133-1144
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• 2000

This study was conducted to evaluate the effects of the program for the autistic children which was designed to promote mother-child attachment. The subjects of this study were consisted of 11 pairs of mother and child( 7 for participant group:PG, 4 for non-participant group: NPG), who were diagnosed as Pervasive Developmental Disorder. The intervention was consisted with play activity centered mother-child interaction, educational activity for mothers, lecture, video-feedback, and supports. The main data were collected by video-taping and analyzed by Wilcoxon Rank Sign Test, and Content Analysis. The results obtained were as follows, 1. Before the program, there were no significant group differences on the children's and the mother's characteristics. After the program, total score on the attachment of PG was higher than that of NPG, but not significant. Only proximity-seeking behaviors and contact-maintaining behaviors were higher significantly(p<.05). Then the characteristics on contact- maintaining behaviors of PG were lasting longer and reciprocal than those of NPG. 2. After the program, the score on mother's nurturing behavior of PG was significantly more increased. The mother's behaviors to her child of PG became more child- centered, positively responsive, expressive supportively. But there were pretty big individual difference. It can be concluded that Mother-child Attachment Promotion Program is effective. Thus it can be recommended to be a early intervention model for autistic children.

• Journal of East-West Nursing Research
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• v.22 no.1
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• pp.1-9
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• 2016

Purpose: We conducted a literature review for analyzing the effect of massage on children according to their developmental stage in Korea. Methods: Various academic databases were utilized for a bibliographic search, and the keyword, 'massage', was used to identify relevant references without limits on years to determine the overall research trends. Finally, 38 references cited from 1998 to 2014 were selected in Korea. Results: Only two studies adapted a randomized controlled trial design. With regard to children's developmental stage, half studies were conducted for neonates. Moreover, the percentage of application of a sensory stimulation protocol in newborn infants was 47.3%. Eighty four point one percent of studies measured physiological characteristics as outcome variables and the rate of growth was the most common (46.5%) physiological characteristic. On the contrary, only one study (4%) was conducted to evaluate the effect of massage on psychological characteristics in school aged and the adolescents. Conclusion: This study provides fundamental data on the development and direction for future studies by analyzing studies on pediatric massage in Korea.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.8 no.2
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• pp.256-265
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• 1997

Objectives：The purpose of this study was to investigate the characteristics and differences of brain function in pervasive developmental disorder and developmental language disorder. Method：The subjects were composed of 14 cases of pervasive developmental disorder and 13 cases developmental language disorder. They were investigated by technitium-99m-EDC SPECT. All SPECT were visually assessed by two nuclear medicine specialists, and then quantified by region of interest including temporal, parietal cortex, thalamus, basal ganglia and cerebellum. Result：In both groups, cerebral blood flow was decreased in the temporal, parietal cortex, basal ganglia, thalamus, cerebellum by visual assessment. There was no significant difference between the 2 groups by quantitative and qualitative assessment. Conclusion：These results suggest that pervasive developmental disorder and developmental language disorder are caused by defects in the interneural connection and that both disorders are spectrum disorders.

• Proceedings of the KSAR Conference
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• 2001.03a
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• pp.68-68
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• 2001

Blastocyst formation, consisting of the inner cell mass (ICM) and trophectoderm (TE), is the first differentiation process during embryonic development in mammals. It has been hypothesized that the proportion of ICM to TE in the blastocyst may be crucial for subsequent developmental competence of early embryos, which it may be expressed as a sensitive indicator for evaluating in vitro systems. In this study ICM/total cell ratio of nuclear transfer (NT) embryos was compared with IVF-derived and in vivo embryos. Somatic cell nuclei obtained from a fetus at Day 40 of gestation were transferred into the enucleated oocyte and then cultured in NCSU 23 medium for 6 days as previously described (Koo et al., Biol. Reprod. 2000; 63:986-992). ICM and TE cells of blastocysts were determined by using a differential staining method (Han et al., Biol. Reprod. 1999; 60:1110-1113). Development rate (9.8$\pm$2.5%, 23/225) to the blastocyst stage of NT embryos was lower than IVF embryos (23.8$\pm$2.7%, 53/223). Thus, a difference was detected in the in vitro developmental rate to blastocyst stage between NT and IVF-derived embryos (P<0.05). In the next experiment, we investigated ICM and TE nuclei to assess the quality of blastocysts that produced by NT, IVF and in vivo, respectively. NT blastocysts (27.6$\pm$8.3) showed a smaller total cell number than IVF-derived (42.6$\pm$17.4) and in vivo embryos (283.9$\pm$103.5) (P<0.05). Ratios of ICM/total cells in NT, IVF and in vivo blastocysts were 15.1$\pm$ 18.6% (n=56), 12.3$\pm$9.2% (n=57) and 30.4$\pm$6.8% (n=40), respectively. Individual blastocysts for the ratio of ICM/total cells were assigned to 3 groups (I; <20%, II; 20 to 40% and III;>40%). As the results, most in vivo blastocysts (97.5%, 39/40) were distributed into group II while most NT (78.6%, 44/56) and IVF-derived blastocysts (82.5%, 47/57) were allocated to group I. Thus, our data show that NT or IVF-derived embryos have aberrant morphology during early development in vitro systems, suggesting that these anomalies may result in developmental failures of the NT embryos to term.

• Development and Reproduction
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• v.17 no.2
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• pp.87-97
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• 2013

The seminiferous epithelium cycle and developmental stages of spermatids in Clethrionomys rufocanus were observed under a light microscope. The seminiferous epithelium cycle was divided into 8 stages. Type Ad spermatogonia appeared through all stages. Type Ap, In, and B spermatogonia appeared in stages I, II, III, and IV. In the first meiosis prophase, the leptotene spermatocytes appeared from stage V, the zygotene spermatocytes in stages I, VI, VII, VIII, the pachytene spermatocytes from stages II to VI, the diplotene spermatocytes in stage VII. The meiotic figures and interkinesis spermatocytes were observed in stage VIII. Developing spermatids were subdivided into 10 steps, based on the morphological characteristics such as the acrosome formation changes in spermatozoa, nucleus, cytoplasm, and spermiation changes. The C. rufocanus spermatocytogenesis and spermiogenesis results displayed similar results with Apodemus agrarius coreae and A. speciosus peninsulae. Considering all the results, the spermatogenesis may be useful information to analyze the differentiation of spermatogenic cells and the breeding season.

• The Journal of the Convergence on Culture Technology
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• v.9 no.4
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• pp.201-210
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• 2023

The purpose of this study is to analyze the general characteristics, effect size, and qualitative indicators of self-advocacy studies of people with developmental disabilities published in domestic academic journals and theses. For this purpose, among a total of 2153 papers related to self-advocacy published from 2000 to 2023, 41 studies with developmental disabilities as the keyword were selected, and the specific research results are as follows. Based on the results of this study, when developing a language intervention program related to self-advocacy for people with developmental disabilities, it is recommended to develop an intervention program based on the number of sessions of 10-19 in a learning situation with 20-30 people in adolescents and adults, or during the transition period. There are many studies limited to educational aspects such as special education and integrated education, and by applying this, it is hoped that a self-advocacy language intervention program will be developed at the level of language rehabilitation that can effectively and sophisticatedly assert self-assertion and self-rights after experiencing difficulties in communication.

• Imaging Science in Dentistry
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• v.53 no.4
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• pp.303-312
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• 2023

Purpose: This study investigated the prevalence of developmental and acquired pathologic conditions associated with impacted third molars (3Ms) in a Southern Brazilian population and evaluated whether demographic and tooth characteristics were correlated with the presence of bone or tooth lesions. Materials and Methods: Panoramic radiographs were assessed for developmental (bone-related) or acquired (tooth-related) pathoses associated with impacted upper or lower 3Ms. Data on tooth positioning, tooth development, and patient demographics were collected. A trained, calibrated postgraduate student evaluated all images. Binary and multivariate logistic regression models were used to assess associations between outcomes and the demographic and radiographic variables. The threshold for statistical significance was set at 5% (P<0.05). Results: The sample comprised panoramic radiographs from 2054 patients, predominantly female (59.2%), with a mean age of 27.2±11.5 years. Overall, 4066 impacted 3Ms were evaluated, revealing 471 (11.6%) developmental and 710 (17.5%) acquired pathoses. Among the developmental pathoses, 460 (95.2%) were indicative of dentigerous cysts. Male sex, lower 3M location, vertical or distoangular positioning, and incomplete root formation were associated with an elevated likelihood of developmental pathology. Lower tooth position, complete root formation, and partial eruption were linked to an increased probability of an acquired pathology in the third or second molar. Conclusion: The prevalence of pathologic conditions associated with impacted 3Ms was low. Male sex, lower 3M placement, horizontal or distoangular positioning, and incomplete root formation were associated with developmental pathoses, while lower tooth position, complete root formation, and partial eruption were related to acquired pathoses.

• The Korean Journal of Ecology
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• v.8 no.4
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• pp.179-196
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• 1985

By using temperatures as a key variable, a simulation model was constructed to predict the size and developmental speed for the German cockroach population. The following three research steps were conducted to implement the individual simulation technique to represent the basic life system of the cockroach. First, informations on developmental periods and survival rates in each life stage were obtained through rearing experiments at five different temperatures. Secondly, biological parameters needed for modeling were obtained based on these rearing results. The logistic equation was applied to calculating the developmental speed, while the averages of survival rates were utilized as parameters determining population size. And thirdly, a basic life model was constratued in a stimulative framework in FORTRAN for predicting the populating development on the individual basis. For this purpose the biological characteristics, such as life stage, age in days, developmental speed, fecundity, etc., were assigned as an inherent attribute of the transactiion so that they could accompany each individual automatically all through the simulation. This gave the model flexibility and applicability in representing the isnect life system. The save memory space in computer programing, two files were utilized in translocating the individual informations each other as time proceeded. The developed model could be effectively used as a strategic tool in interpreting and managing the cockroach population. It was also suggested in this study that the individual simulation could efficiently serve as a basis to formulate a fundamental framework on which the advanced and complex life process could be built.