• Clinical and Experimental Reproductive Medicine
• /
• v.21 no.1
• /
• pp.77-81
• /
• 1994

To improve in vitro embryonic cell development, this study was desigend to culture in vitro fertilized early embryos of mouse in two different systems; conditioned medium alone and ampullary cells co-culture. Thirty two of 83 embryos(38.6%) were blocked in the 2 cell stage by co-culture, as compared to forty of 42 embryos(95.2%) in control group for 24hours culture. And all the embryonic cells cultured for conditioned medium alone were blocked for 48 hours culture. Twenty seven of 46 embryos (58.7 %) which overcome culture block in 2 cell stage by cocultured were developed morular and expanded blastocyst, and ninteen of 46 embryos(26.1 %) underwent hatching for 96 hours culture. The cellular fragmented rates for embryo were 26.2% in medium alone; 10 fragmented blastomere were graded mild status and 1 fragmented blastomere in severe status. On the other hand, the fragmented rate for 48 hours co-cultured were 15.7%03/83); 8 fragmented embryos were graded mild status, moderate status in 3 fragmented embryos and severe in 2 fragmented embryos respectively. In conclusion, the co-culture of embryos with ampullary cells is good to improve quality of embryos and overcome of culture block as well as development of cell cleavage.

• Journal of the Korean Home Economics Association
• /
• v.42 no.7
• /
• pp.1-17
• /
• 2004

This study was conducted to determine the influence of socio-economic status of potential consumers on the types of senior congregate housing(SCH) among 4 urban areas(Seoul Metropolitan area, Busan, Gwangaju, and Daejun). This study was part or a research series to develop SCH which meets the korean situation. The Questionnaire used for the final analysis involved 1006 people and SPSS Windows program was used for statistical analysis. The opinion about SCH should differ among the 4 urban areas according to Socio-Economic Status(SES). The results of this study were as follows: The opinions on SCH varied in each region according to SES indicating that diverse constructions of senior housing to meet selective needs of the old can create high demand in a construction market. In order to induce active participation of the private sector, the Ministry of Construction and Transportation, rather than the Ministry of Health and Welfare, should be in charge of the development of SCH. This is desirable in the perspective of developing new types of housing as for general housing. In this case, the Ministry of Construction and Transportation should consider geographic locations and environmental factors of each city. Moreover, the successful development of SCH needs an effort to reexamine an appropriate development plan rather than adopting the cases of developed countries without criticism. In terms of policies, the government should provide financial support for building sharing space, give an exception on a measurement rate, assist in the education of supervisors and establish a management system and so on.

• Journal of Ginseng Research
• /
• v.31 no.3
• /
• pp.159-174
• /
• 2007

Pharmacology of Korean Red ginseng gives us unique possibility to develop new class of antiepileptic drugs today and to improve one's biological activity. The chemical structures of ginsenosides (GS) have some principal differences from well-known antiepileptic new generation drugs. The antiepileptic effect of GS was also demonstrated in all models of epilepsy in rats (young and adult), which have studied, in all models of epilepsy including status epilepticus (SE), induced by lithium - pilocarpine. In our experiments in rats new evidences on protective effects were exerted as a result of premedication by GS. Pre-treatment of several GS could induce decrease of the seizures severity and brain structural damage (by MRI), neuronal degeneration in hippocampus. Wave nature of severity of motor seizures during convulsive SE was observed during lithium-pilocarpine model of SE in rats (the first increase of seizures was 30 min after the beginning of SE and the second - 90 min after. The efficacy of treatment on SE by ginsenoside as expected was observed after no less 3 weeks by daily GS i.p. administration. It is blocked SE or significantly decrease the severity of seizures during SE. The implication of presented data is that combination of ginsenosides from Korean Red ginseng and ginseng cell culture Dan25 that could be applied for prevention of epileptical status development. However, a development of optimal ratio of different ginsenosides $(Rb_1$ Rc, Rg, Rf,) should consummate in the new antiepileptic drug development.

• Child Health Nursing Research
• /
• v.20 no.4
• /
• pp.255-263
• /
• 2014

Purpose: The purpose of this study was to examine relationship of preschool child and mother interaction, child's health status, health-related quality of life and social development. Also, it was intended to provide a basis for development of mother-child interaction programs. Methods: The present study was a descriptive research. Participants in this study were a convenience sample of 230 preschool children and their mothers. For the final analysis 209 questionnaires were used after eliminating questionnaires with incomplete responses. Data were analyzed using the SPSS 18.0 program. Results: The mean score for interaction between preschool child and mother was $3.96{\pm}0.55$ out of 5 points, for child health status, $3.75{\pm}0.62$ out of 5 points, for child's health-related quality of life, $83.89{\pm}10.20$ out of 100 points and for child's social development, $19.66{\pm}3.57$ out of 24 points. Positive correlations were found between interaction of preschool child and mother, child's health status, health-related quality of life, and social development. Conclusion: The results demonstrate the importance of the quality of the relationship between mother, the child's primary caregiver, and her child for the healthy growth and development of preschool children. It is suggested that intervention programs for preschool child-mother interaction should be developed using evidence based data.

• The Journal of Korean Medicine
• /
• v.45 no.1
• /
• pp.257-270
• /
• 2024

Objectives: Korea has a unique history of being both a recipient and a donor of Official Development Assistance (ODA), and the international community expects Korea to contribute to the development of developing countries by utilizing this experience. Traditional Korean medicine (TKM) seeks to contribute to global health, however the concept of ODA has been unclear and there has been no clear strategy and sustainable initiatives. Methods: This study examines the concept of ODA and its application in global health, including business objectives, scale, evaluation principles, and development strategies. Additionally, we reviewed the current status of Traditional Korean medicine globalization projects and conducted a SWOT analysis of the internal and external environment of the TKM sector. Based on these findings, we redefined the concept of ODA for TKM and proposed suggestions for its development. Results: The current study identified key ideas for TKM ODA. It should prioritize the improvement of primary healthcare in recipient countries, aligning with the international evaluation criteria of the SDGs. Secondly, TKM's 70 years of experience can be leveraged to enhance both the competence and economic benefits of recipient countries' medical systems. Based on these concepts, a TKM ODA development model was proposed, comprising two core visions, three development strategies and goals, and six core values. Conclusion: This study systematically examined the TKM in global health and suggested sustainable development strategies for TKM ODA. Through its expansion, TKM could contribute to the advancement of global traditional medicine and its overall engagement in healthcare.

• The Korean Journal of Rehabilitation Nursing
• /
• v.11 no.1
• /
• pp.41-48
• /
• 2008

Purpose: The study were to identify difference in self-efficacy according to perceived health status in male smokers. Methods: The subjects were 138 male smoker in Seoul and Incheon. The data was collected using structured questionnaires from ninth of July to 16th of August in 2007. The data was analyzed by descriptive statistics and ANOVA with SPSS 14.0. Result: Participants showed that a high level of total self-efficacy score $3.40{\pm}.43$, general self-efficacy score $3.39{\pm}.46$, social self-efficacy score $3.44{\pm}.55$. There were significant difference total self-efficacy and general self-efficacy in accordance with perceived health status. But there were no significant difference social self-efficacy in accordance with perceived health status. With the result of this study, the subjects smoked $14.48{\pm}11.04$ years and 90.4% of the subjects were highly perceived that the health status of oneself above of moderate state and self-efficacy score. Conclusion: Therefore raising a perception about smoking dangerous, the prohibition of smoking program development which emphasizes the noxiousness of smoking for must precede, recognizes the necessity of prohibition of smoking and prohibition of smoking decision in one smoker comes to seem with the fact that own effect increase program for a prohibition of smoking maintenance.

• Journal of Korean Public Health Nursing
• /
• v.34 no.1
• /
• pp.99-111
• /
• 2020

Purpose: This study was conducted to verify model for predicting health promotion behavior and the health status of child care teachers based on Pender's health promotion model and Dahlgren and Whitehead's health determinants model. Methods: The data was collected from January to February 2018 from 205 child care teachers in day care centers in Seoul. Results: This model was suitable to explain the health status and health promotion behavior of child care teachers. In this study, health promotion behavior had the most direct affect on the health status of child care teachers. Health promotion behavior was directly affected by social support, self-efficacy, and depression. Job stress had an indirect affect on health promotion behavior. Conclusion: Considering the factors identified in this study that influence the health promotion behavior of child care teachers, we propose the development of interventions to improve the health status of child care teachers.

• Korean Journal of Adult Nursing
• /
• v.27 no.2
• /
• pp.198-210
• /
• 2015

Purpose: This study was to develop a health promotion program for marriage immigrant women and to evaluate its efficacy. Methods: The health promotion program was comprised of eight 100-minute weekly sessions. Each session included understanding of health responsibility, nutrition, physical activity, interpersonal relations, stress management, and self actualization. The research was conducted under the principles of nonequivalent control group pretest-post test design. The outcome variables were health promoting behavior, health status, acculturation, self efficacy, and perceived barrier. The participants were 15 immigrant women in the experimental group and 16 in the control group. Data was analyzed using ${\chi}^2$ test, Fisher's exact test, Mann Whitney U-test and Wilcoxon signed rank test. Results: There was a significant improvement in health promoting behaviors (U=-3.08, p=.002), left shoulder flexibility (U=-3.02, p=.003), right shoulder flexibility (U=-3.02, p=.003), low back flexibility (U=-3.37, p=.001), social health status (U=-3.38 p=.001) and subjective health status (U=-2.17 p=.030) in the experimental group compared to the control group. Conclusion: The health promotion program for marriage immigrant women was an effective intervention for improving health promoting behavior, physical health status, social health, and subjective health status. Therefore, the developed health promotion program needs to be applied to married immigrant women in other kinds nursing care settings in future research.

• Journal of Korean Public Health Nursing
• /
• v.27 no.1
• /
• pp.179-189
• /
• 2013

Purpose: This study was conducted to evaluate the effects of a brown rice and vegetable dietary program on the defecation conditions and health status of high school students. Method: A non-equivalent control group and pretest-posttest design was used. The subjects were 62 students (28 in the intervention group, 34 in the control group) who voluntarily participated in the study. The program was conducted from April 6, 2012 to July 3, 2012 at two high schools in Daegu city. During that time, two meals a day were supplied to the experimental group. Data on defecation condition and health status was collected using self-questionnaires. Results: After 12 weeks, students in the intervention group had a significantly better defecation condition than students in the control group. Students in the intervention group also had a significantly higher health status than students in the control group. Conclusion: The results suggest that a brown rice and vegetable dietary program improves the defecation condition and health status of high school students. Therefore, the development and study of nursing intervention and public health education program about brown rice as well as vegetable and fresh fruit consumption are necessary for these subjects.

• Journal of Nutrition and Health
• /
• v.32 no.2
• /
• pp.175-181
• /
• 1999

The prevalence of alcoholism among elderly population is reported to be high in rural areas in Korea. Chronic abuse of alcohol can lead to the development of vitamin B deficiency through inadequate intake, altered absorption and metabolism, and increased excretion. The present study was conducted to assess vitamin B1 and B2 status in seventeen alcohol dependent subjects who do not exhibit any clinical neurological symptoms. Vitamin B1 and B2 nutritional states were determined enzymatically by measurement of transketolase and glutathione reductase activities in erythrocytes, respectively. And dietary intakes of nutrients were determined by a 24-hr recall method. The mean percent activation of erythrocyte transketolase was significantly higher in alcoholics than in alcoholics than in control (p<0.05). The proportion of subjects with a low and borderline status of vitamin B1, was significantly higher in alcoholics than in control (p<0.05). The mean percent activation of erythrocyte glutathione reductase was not different between alcoholics and control. And the proportion of subjects with low and borderline status of Vitamin B2, was higher in alcoholics than in control (p<0.1). Vitamin B1 and B2 status were significantly decreased in alcoholics who were smoking cigarettes compared to non-smoking and non-alcoholic subjects(p<0.05). Whether vitamin supplementation improves the vitamin status of alcohol dependent subjects remains to be researched.