• Education of Primary School Mathematics
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• v.3 no.2
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• pp.89-101
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• 1999

The reform movements of current mathematics education have based on several major ideas, in order to provide a new vision of the teaching and loaming of mathematics. Of the ideas, the motto of communication of mathematics appears to be a significant factor to change teaching practices in mathematics classroom. Through Vygotsky's sociocultural theory, the psychological background is presented for both supporting the motto and extracting important suggestions of the reform of mathematics education. The development of higher mental functions is explained by internalization, semiotic mediation, and the zone of proximal development. Above all, emphasis is put on the concepts of scaffolding and inter subjectivity related to the zone of proximal development. Seven implications are proposed by Vygotsky's sociocultural theory for the new forms of the teaching and learning of mathematics.

• Journal of Agricultural Extension & Community Development
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• v.27 no.4
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• pp.199-210
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• 2020

This study aims to find out the differences of community satisfaction between rural and urban residents and identify factors influence community satisfaction. The secondary data designed and surveyed by Rural Development Administration in 2018 were used in this study. The total respondents were 3,929; rural 2,780 and urban 1,149 respectively. The major findings were as follows; First, the level of community satisfaction showed satisfactory in both region, however, level of urban residents were more high than rural. Secondly, perceive safety factor(4 variables) was the most influential in both area. The variances explained were 5.2% in rural and 10.5% in urban.

• Development and Reproduction
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• v.27 no.4
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• pp.221-226
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• 2023

A stem cell niche provides an environment that governs stem cell maintenance and division. Thus, the development of a proper niche is of prime importance to stem cell behaviors. Mechanisms of niche development are beginning to be revealed in the Drosophila male gonad. Niche cells are initially dispersed throughout the gonad, then assemble at its apical tip through the anterior migration of posteriorly located niche cells. The molecular mechanisms of this migration and assembly are still poorly understood. Here we show evidence suggesting that Lin28, an RNA-binding protein and regulator of let7 genesis, might be an intrinsic factor for the anterior migration of niche cells. We found that a dispersed, ectopic niche, a phenotype observed with anterior migration defects, occurs in lin28 mutant gonads. This phenotype is rescued by expression of lin28 in the niche cells. These findings suggest that Lin28 might be required for the anterior migration of niche cells.

• Clinical and Experimental Vaccine Research
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• v.13 no.2
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• pp.91-104
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• 2024

This narrative review describes genomic characteristic, serotyping, immunogenicity, and vaccine development of Streptococcus pneumoniae capsular polysaccharide (CPS). CPS is a primary virulence factor of S. pneumoniae. The genomic characteristics of S. pneumoniae CPS, including the role of biosynthetic gene and genetic variation within cps (capsule polysaccharide) locus which may lead to serotype replacement are still being investigated. One hundred unique serotypes of S. pneumoniae have been identified through various methods of serotyping using phenotypic and genotypic approach. The advantages and limitations of each method are various, emphasizing the need for accurate and comprehensive serotyping for effective disease surveillance and vaccine targeting. In addition, we elaborate the critical role of CPS in vaccine development by providing an overview of immunogenicity, ongoing research of pneumococcal vaccines, and the impact on disease burden.

• Fisheries and Aquatic Sciences
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• v.5 no.2
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• pp.127-135
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• 2002

Twenty seafood samples, which are common edible species and commercially important items in Korea, were purchased at the local fisheries markets and were analyzed for polycyclic aromatic hydrocarbons (PAHs) using gas chromatography coupled to mass spectrometer detector (GC/MSD). The levels of sixteen PAHs in seafood from Korean coasts were 161 to 2,243 pg/g wet weight. The highest concentration was found at saury (Coloabis saira) and the lowest level was found at jacopever (Sebastes schlegeli). The concentrations of potentially carcinogenic PAHs of six species were in the range of 9 to 123 pg/g wet weight. The residues of PAHs in fishes from Korean coasts were slightly low or relatively moderate to other countries. There was no correlation between PAH residues and lipid contents in seafood samples. The predominant contributors in fish samples were lower-molecular-weight two and three ring aromatic PAHs such as naphthalene, acenaphthene, fluorene and phenanthrene. Filter-feeding organisms like shrimp, crab and topshell were dominated by three- and four-ring aromatic PAHs. The PAH profiles in marine sediments, bivalves, fishes, shrimp, crab and topshell according to exposure pathway were compared through factor analysis. The PAH profiles were clearly classified by the difference of species or environmental matrices. This result suggests that most of PAHs within the same samples behave identically in marine environment.

• Journal of Korean Academy of Nursing
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• v.3 no.1
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• pp.97-104
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• 1972

This study was designed to investigate differences in some aspects of value conceptions in fundamentals of nursing functions between nursing service personnel and nurse-educators. The purpose of the study was to identify the difference of value conceptions between the hospital nurses and school instructors, to contribute as a reference in strengthening the educational program in establishing nay hinder professional growth. The questionaries of this study were focused in the following aspects: 1) establishment of nursing service management system, 2) strengthening of the professionalization of nursing service, 3) hindrance in accomplishment of independent nursing functions, 4) communication skills in nurse-patient relationship, 5) activities directly related to nursing care planning, 6) communication skills in nurse-doctor relationship, 7) attitude towards taking responsibilities for patient- centered nursing approach, and 8) nursing educational approach towards preparation of professional competence in practicing independent nursing functions. 265 graduate nurses from 14 general hospitals and 88 nursing instructors from 18 schools, collegiate and diploma, were sampled. The main findings of the study were as follows; 1. Both groups responded highly in the lack of public recognition of nursing profession and hospital administrators support in establishment of nursing service management system. Further investigation is needed to define some relationship between the intrinsic and extrinsic factors which might give influence to the professional development. 2. while hospital nursing personnel responded on environmental pressure such as a heavy nursing load as the factor giving hindrance to independent nursing functions, the nurse educators responded highly on lack of nursing competence of individual nurses. An emphasis should be placed on the development of nursing interaction through professional education. If the professional model is not well established, nursing function will be limited to medical assistance. 3. 3. The patient-centered approach for nurse-patient communication had given positive respond for both group, tut lacks in team concept in problem solving process. There exist a social distance between nurses and other professional co-workers in the hospital hierarchy. 4. It was indicated that, as an intrinsic factor in the development of nursing service and nursing education, building up a philosophical basis is an utmost importance. This question is opened for further and extensive study to clarify whether existence of philosophical absence or philosophical stasis in nursing profession hinders the development.

• Journal of the Korean Institute of Landscape Architecture
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• v.23 no.4
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• pp.50-60
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• 1996

The purpose of this study is to investigate the prime factors that affect user satisfaction of area and facilities in urban forests, to classify those factors, to find out factorial structure of user satisfaction about them, and then to suggest important indicators in the urban forest planning, design, and development. The survey research was done using the self-administered questionnaire method by the people in the city of the Pusan who participated in recreational activities in the Mt. Keumjung. Factor analysis was used to extract the prime factors related to the recreational satisfaction concerning the area and facilities of the urban forest by the SPSS program, and then prime factors were used to investigate the factorial structure of user recreational satisfaction in the urban forest by the LInear Structure RELation program. According to the factor analysis concerning the 13 variables, 4 prime factors by the statistical values were considered as effective, indicating, 'health and recreational facilities', 'convenience and management facilities','facilities for the physical and psychological training' and 'historical and cultural areas'. The results of the causal structure analysis were identified as having significant effects mutually on endogenous variables, 'overall recreational satisfaction of the areas and facilities in the Mt. Keumjung','health and recreational facilities','convenience and management facilities','facilities for the psychological training', and 'historical and cultural areas'. But exogenous variables which have significant effects on endogenous variables were also indentified. Overall fits of both causal model were very good. The hypothetical causal structural equation models based on the results found partially significant correlation between dndogenous variables and between envogenous and exogenous variables. These significant relationships indiate important factors and variables that should be considered in planning, design, and development of the urban forests. Therefore, development direction of the Mt. Keumjung has to be analyzed as significant factors concerning user recreational satisfaction in a systematic was, recognized as important variables for planning process. The plan for development and management also should reflect the natural conservation policy from the environmental conservation movement like natural conservation advertisement and environmental education.

• Archives of design research
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• v.11 no.2
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• pp.117-126
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• 1998

The underground space which has been highlighted anew in view of urban scenery and environmental conservation through the control of ground development and solution of urban problems through making the utility of urban space efficient can promote the urban service, amenity, stability and others by arranging the urban function of ground area to the underground which is anticipated to be demanding the more in the future an also can be effective measures of confrontation in the solution of traffic, the complex in the heart of the city and lack of land through effective construction of the structure of urban space. But it has been understood to be extremely negative space at this time as limited to negative and fragmentary development and it has faced the necessity of constructing pleasant environment by overcoming every problem. After all, through the general research of underground space, this dissertation is reconsidering the development value of environmental design on the basis of the case study in international city development of underground space, and trying to extract design factors which should be treated in developing the underground space by establishing the evaluation model on the functional, techinical and behavioral elements factors.

• Korean Journal of Remote Sensing
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• v.27 no.6
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• pp.637-651
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• 2011

This study presents a rule-based urban image classification method for time series analysis of changes in the vicinity of Asan-si and Cheonan-si in Chungcheongnam-do, using Landsat satellite images (1991-2006). The area has been highly developed through the relocation of industrial facilities, land development, construction of a high-speed railroad, and an extension of the subway. To determine the yearly changing pattern of the urban area, eleven classes were made depending on the trend of development. An algorithm was generalized for the rules to be applied as an unsupervised classification, without the need of training area. The analysis results show that the urban zone of the research area has increased by about 1.53 times, and each correlation graph confirmed the distribution of the Built Up Index (BUI) values for each class. To evaluate the rule-based classification, coverage and accuracy were assessed. When Optimal allowable factor=0.36, the coverage of the rule was 98.4%, and for the test using ground data from 1991 to 2006, overall accuracy was 99.49%. It was confirmed that the method suggested to determine the maximum allowable factor correlates to the accuracy test results using ground data. Among the multiple images, available data was used as best as possible and classification accuracy could be improved since optimal classification to suit objectives was possible. The rule-based urban image classification method is expected to be applied to time series image analyses such as thematic mapping for urban development, urban development, and monitoring of environmental changes.

• Journal of Korean Dental Science
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• v.9 no.1
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• pp.9-18
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• 2016

Purpose: Wnt signaling plays an essential role in the dental epithelium and mesenchyme during tooth morphogenesis. Deletion of the Wntless (Wls) gene in odontoblasts appears to reduce canonical Wnt activity, leading to inhibition of odontoblast maturation. However, it remains unclear if autonomous Wnt ligands are necessary for differentiation of dental pulp cells into odontoblast-like cells to induce reparative dentinogenesis, one of well-known feature of pulp repair to form tertiary dentin. Materials and Methods: To analyze the autonomous role of Wls for differentiation of dental pulp cells into odontoblast-like cells, we used primary dental pulp cells from unerupted molars of Wls-floxed allele mouse after infection with adenovirus for Cre recombinase expression to knockout the floxed Wls gene or control GFP expression. The differentiation of dental pulp cells into odontoblast-like cells was analyzed by quantitative real-time polymerase chain reaction. Result: Proliferation rate was significantly decreased in dental pulp cells with Cre expression for Wls knockout. The expression levels of Osterix (Osx), runt-related transcription factor 2 (Runx2), and nuclear factor I-C (Nfic) were all significantly decreased by 0.3-fold, 0.2-fold, and 0.3-fold respectively in dental pulp cells with Wls knockout. In addition, the expression levels of Bsp, Col1a1, Opn, and Alpl were significantly decreased by 0.7-fold, 0.3-fold, 0.8-fold, and 0.6-fold respectively in dental pulp cells with Wls knockout. Conclusion: Wnt ligands produced autonomously are necessary for proper proliferation and odontoblastic differentiation of mouse dental pulp cells toward further tertiary dentinogenesis.