• Title/Summary/Keyword: Development factor

Search Result 10,331, Processing Time 0.041 seconds

Dietary methionine supplementation to a low-protein diet improved hair follicle development of Angora rabbits

  • Man Zhao;Tongtong Wang;Bin Wang;Chuanhua Liu;Fuchang Li;Lei Liu
    • Animal Bioscience
    • /
    • v.36 no.6
    • /
    • pp.920-928
    • /
    • 2023
  • Objective: Angora rabbits fed a low-protein diet exhibit decreased hair production performance. This study was set out to evaluate the effects of methionine on hair properties and nitrogen metabolism in Angora rabbits fed a low-protein diet and to investigate the gene expression related to hair follicle development to determine the possible molecular mechanism of methionine effects on hair follicle development. Methods: An experiment was conducted to investigate the effects of DL-methionine addition on a low-protein diet on hair development in Angora rabbits. Angora rabbits were divided into 5 groups: fed a normal diet (control), fed a low-protein diet (LP), or fed an LP supplemented with 0.2%, 0.4%, or 0.6% DL-methionine (Met). Results: The results showed that rabbits in the LP group had lower wool yield than the control rabbits, but the addition of 0.4% to 0.6% Met to LP attenuated these effects (p<0.05). Dietary addition of 0.4% to 0.6% Met to LP increased the apparent nitrogen digestibility, nitrogen utilization rate, and feed efficiency (p<0.05). Feeding LP decreased the insulin-like growth factor 1 (IGF1), keratin-associated protein (KAP) 3.1, and KAP 6.1 mRNA levels compared with the control, but the addition of 0.4% Met in LP attenuated these effects (p<0.05). Relative to the LP or control group, dietary addition of 0.4% Met increased versican mRNA levels. Conclusion: In conclusion, the addition of Met to LP could improves wool production performance and feed efficiency and reduce nitrogen emissions in Angora rabbits. Met can promote hair follicle development, which may be associated with IGF1, KAP, and the versican signaling.

Effect of Cold Plasma on Total Polyphenol Content and Anti-Inflammatory Activities of Peanut (Arachis hypogaea L.) Hull

  • Mihyang Kim;Yeo Ul Cho;Narae Han;Jin Young Lee;Yu-Young Lee;Moon Seok Kang;Hyun-Joo Kim
    • Proceedings of the Korean Society of Crop Science Conference
    • /
    • 2022.10a
    • /
    • pp.330-330
    • /
    • 2022
  • In recent studies, cold plasma has been used to induce exudation of polyphenols and flavonoids from food materials, leading to enhancement of functional properties. And it is known that polyphenols interact with inflammation related metabolism. The objectives of this study were to investigate the effects of cold plasma treatments on the increase of total phenolic content (TPC), total flavonoid content (TFC), and anti-inflammatory activities of 'Sinpalkwang' peanut (Arachis hypogaea L.) hull. Plasma treatments were carried out using a dielectric barrier discharge gas exchange system at different radicals and temperatures (O3-25℃, O3-150℃, NOx-150℃). Significant differences in TPC, TFC, and inflammatory mediator such as nitric oxide (NO) and tumor necrosis factor a (TNF-α) in lipopolysaccharide stimulated Raw 264.7 macrophages were observed between treated and non-treated peanut hull samples (p < 0.001). Cold plasma treated samples showed higher content (TPC: 2.87-2.93 mg/g sample, TFC: 0.96-0.98 mg/g sample) than non-treated sample (TPC: 2.47 mg/g sample, TFC: 0.78 mg/g sample). Cold plasma treated samples showed lower content of NO (3.3-5.0 uM) and TNF-α (141.4-162.2 ng/mL) than non-treated sample (NO: 11.1 uM, TNF-α: 210.2 ng/mL). This study suggests that cold plasma has potential to improve functionalities of food materials and that cold plasma treated peanut hull can be used as immune enhancing materials.

  • PDF

Tuning for Temperature Coefficient of Resistance Through Continuous Compositional Spread Sputtering Method (연속 조성 확산 증착 방법을 통한 저항 온도 계수의 튜닝)

  • Ji-Hun Park;Jeong-Woo Sun;Woo-Jin Choi;Sang-Joon Jin;Jin-Hwan Kim;Dong-Ho Jeon;Saeng-Soo Yun;Jae-Il Chun;Jin-Ju Lim;Wook Jo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.37 no.3
    • /
    • pp.323-327
    • /
    • 2024
  • The low-temperature coefficient of resistance (TCR) is a crucial factor in the development of space-grade resistors for temperature stability. Consequently, extensive research is underway to achieve zero TCR. In this study, resistors were deposited by co-sputtering nickel-chromium-based composite compositions, metals showing positive TCR, with SiO2, introducing negative TCR components. It was observed that achieving zero TCR is feasible by adjusting the proportion of negative TCR components in the deposited thin film resistors within certain compositions. Additionally, the correlation between TCR and deposition conditions, such as sputtering power, Ar pressure, and surface roughness, was investigated. We anticipate that these findings will contribute to the study of resistors with very low TCR, thereby enhancing the reliability of space-level resistors operating under high temperatures.

In Vitro and In Vivo Bone-Forming Effect of a Low-Molecular-Weight Collagen Peptide

  • Jae Min Hwang;Mun-Hoe Lee;Yuri Kwon;Hee-Chul Chung;Do-Un Kim;Jin-Hee Lee
    • Journal of Microbiology and Biotechnology
    • /
    • v.34 no.2
    • /
    • pp.415-424
    • /
    • 2024
  • This study reveals that low-molecular-weight collagen peptide (LMWCP) can stimulate the differentiation and the mineralization of MC3T3-E1 cells in vitro and attenuate the bone remodeling process in ovariectomized (OVX) Sprague-Dawley rats in vivo. Moreover, the assessed LMWCP increased the activity of alkaline phosphatase (ALP), synthesis of collagen, and mineralization in MC3T3-E1 cells. Additionally, mRNA levels of bone metabolism-related factors such as the collagen type I alpha 1 chain, osteocalcin (OCN), osterix, bone sialoprotein, and the Runt family-associated transcription factor 2 were increased in cells treated with 1,000 ㎍/ml of LMWCP. Furthermore, we demonstrated that critical bone morphometric parameters exhibited significant differences between the LMWCP (400 mg/kg)-receiving and vehicle-treated rat groups. Moreover, the expression of type I collagen and the activity of ALP were found to be higher in both the femur and lumbar vertebrae of OVX rats treated with LMWCP. Finally, the administration of LMWCP managed to alleviate osteogenic parameters such as the ALP activity and the levels of the bone alkaline phosphatase, the OCN, and the procollagen type 1 N-terminal propeptide in OVX rats. Thus, our findings suggest that LMWCP is a promising candidate for the development of food-based prevention strategies against osteoporosis.

Assessment of the Heavy Metal Contamination in Paddy Soils Below Part of the Closed Metalliferous Mine (폐금속광산 하류 논토양의 중금속 오염도 평가)

  • Kim, Min-Kyeong;Hong, Sung-Chang;Kim, Myung-Hyun;Choi, Soon-Kun;Lee, Jong-Sik;So, Kyu-Ho;Jung, Goo-Bok
    • Korean Journal of Environmental Agriculture
    • /
    • v.34 no.1
    • /
    • pp.6-13
    • /
    • 2015
  • BACKGROUND: Most of the tailings have been left without any management in abandoned metalliferous mines and have become the main source of heavy metal contamination for agricultural soils and crops in the these areas. METHODS AND RESULTS: This experiment was carried out to investigate the assessment of the heavy metal contamination in paddy soils located on downstream of the closed metalliferous mine. The average total concentrations of cadmium (Cd), copper (Cu), lead (Pb), zinc (Zn), and arsenic (As) in paddy soils were 8.88, 56.7, 809, 754, and 37.9 mg/kg, respectively. Specially, the average concentrations of Cd, Pb and Zn were higher than those of warning criteria for soil contamination(4 mg/kg for Cd, 200 mg/kg for Pb, and 300 mg/kg for Zn) in agricultural soil established by Soil Environmental Conservation Act in Korea. The proportions of 0.1 M HCl extractable Cd, Cu, Pb, Zn, and As concentration to total concentration of these heavy metals in paddy soils were 27.7, 21.3, 35.1, 13.8 and 10.5%, respectively. The pollution index of these five metals in paddy soils ranged from 0.42 to 11.92. Also, the enrichment factor (EFc) of heavy metals in paddy soils were in the order as Cd>Pb>Zn>Cu>As, and the enrichment factor in paddy soil varied considerably among the sampling sites. The geoaccumulation index (Igeo) of heavy metals in soils were in the order as Cd>Pb>Zn>Cu>As, specially, the average geoaccumulation index of Cd, Pb, and Zn (Igeo 2.49~3.10) were relatively higher than that of other metals in paddy soils. CONCLUSION: Based on the pollution index, enrichment factor, and geoaccumulation index for heavy metal in paddy soils located on downstream of closed metalliferous mine, the main contaminants are mine waste materials and mine drainage including mine activity.

Investigation into Development of Injection Mould with High Cooling Characteristics Using Direct Metal RP Technology (직접식 금속 쾌속조형 공정을 이용한 고 냉각 특성 사출 성형 금형 개발에 관한 연구)

  • Ahn, D.G.;Kim, H.W.;Kim, H.S.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
    • /
    • 2007.05a
    • /
    • pp.187-190
    • /
    • 2007
  • The objective of this paper is to investigate into the development of injection mould with high cooling characteristics using a direct metal RP technology. In order to manufacture the injection mould with a high cooling rate, three-dimensional conformal cooling channels have been generated in the mould. DMT process, which is one of direct metal RP technologies, has been utilized to directly manufacture the metallic mould with three-dimensional conformal cooling channels. In order to examine the performance of the designed mould, injection molding tests have been carried out. The results of the experiments have been shown that a cooling time and the injection time of the proposed mould are reduced by the factor of five and two times in comparison with the injection mould with linear cooling channels.

  • PDF

New Perspectives on Plant Defense Responses through Modulation of Developmental Pathways

  • Chung, Kwi-Mi;Igari, Kadunari;Uchida, Naoyuk;Tasaka, Masao
    • Molecules and Cells
    • /
    • v.26 no.2
    • /
    • pp.107-112
    • /
    • 2008
  • Invasion mechanisms of pathogens and counteracting defense mechanisms of plants are highly diverse and perpetually evolving. While most classical studies of plant defense have focused only on defense-specific factor-mediated responses, recent work is beginning to shed light on the involvement of non-stress signal components, especially growth and developmental processes. This shift in focus links plant resistance more closely with growth and development. In this review, we summarize our current understanding of how pathogens manipulate host developmental processes and, conversely, of how plants deploy their developmental processes for self-protection. We conclude by introducing our recent work on UNI, a novel R protein in Arabidopsis which mediates cross-talk between developmental processes and defense responses.

A STUDY ON THE GROWTH OF PRIVATE SECURITY IN THE UNITED STATES (미국(美國) 민간경비의 성장요인 분석)

  • Lee, Chang-Mu
    • Korean Security Journal
    • /
    • no.6
    • /
    • pp.273-289
    • /
    • 2003
  • The purpose of this study is to explore the underlying causes of the development of private security in the United States. These include the increasing crime rates and fear of crime, the poor performance of public policing, the decentralization of political authority, the increase of mass private property, economic growth and increase of personal income, commodification of security, insurance companies' demand for tighter security and fear of litigation, and historical events such as World War I & II. Based on the findings of this study, it is suggested that no single factor would account for the growth of private security in the United States. In other words, the rapid growth of private security in the United States should be attributed to the interrelated influences of the factors given above. Finally, it might be the contribution of this study that the future development of private security in Korea would be guided by understanding the case of the United States because of the similarities of the developmental process in private security industry of two countries.

  • PDF

The Cost Saving Method on Each Building Phase by Analyzing the Cost Structure (비용구조분석에 의한 건축단계별 공사비용 절감방법)

  • Park, Keun-Joon
    • Journal of the Korea Institute of Building Construction
    • /
    • v.5 no.1 s.15
    • /
    • pp.97-103
    • /
    • 2005
  • Building costs means capital costs which include cost of land, costs of acquiring and preparing the site, construction costs, professional fees, furnishings, cost of financing the project. and cost of management required to run and maintenance the building for use. There are several phases that determine the building costs : design phase, construction phase, and operation & maintenance phase. So, the cost of work could be set against the examining the full range of complexities that a building program might contain. To solve this problem, it needs to compute building cost systematically. This is still in the development stage, awaiting the organization of rational cost data base. The method of cost saving by cost control could be constituted by detailed knowledge of building costs for all possible combinations of components and subsystems that can be assembled into integration model of cost factor on each phase of project development. The model of cost saving in each building phase is available for procedures of cost control of building systems.

A Study on the Preference Attributes for Silver Town Development (실버타운 개발을 위한 선호속성에 관한 연구)

  • Ha, Jeung-Soon;Cho, Joo-Hyun
    • Journal of the Korean housing association
    • /
    • v.18 no.3
    • /
    • pp.103-113
    • /
    • 2007
  • The purpose of this study is calling attention to the silver town by analyse preference attributes diversely and suggest alterative plan. Also, offering basic data which needs for the establishment of comfortable and ideal old age residence culture by developing silver town which is appropriate for our circumstances and emotion. The survey population of this study focused on 40s and 50s' middle aged both genders living in the Seoul and national capital region, we used random sampling method. The analytical methods used in this study were frequency, mean, standard deviation, Factor Analysis, t-test, ANOVA, post-hoc estimation (Duncan test), multiple regression, To verify the reliability of each measure, Cronbach's alpha coefficient was used.