• Title/Summary/Keyword: Development factor

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Cyclic Aminoalcohols with C-18 Alkenyl Substituents and Their Nanomolar Level-Activities as Tissue Factor Inhibitors

  • Yoon, Ung-Chan;Kwon, Hyuk-Chul;Cho, Yong-Jin
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.234.2-234.2
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    • 2003
  • Development of new tissue factor (TF) inhibitor is still needed for improved compositions having anticoagulant activity and which can be administed orally or non-intravenously at low doses. Our studies for the development of new TF inhibitors uncovered that aminoalcohols with C-18 alkenyl group, 9-octadecenyl- or 9,12-octadecadienyl groups exhibits in vitro nanomolar level activities. (omitted)

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An empirical study on the sustainable modeling of the multidisciplinary care teams : focus on the chronic disease (만성질병에 있어 다원적 진료팀의 지속가능 모델개발에 관한 실증적 연구)

  • Yu, Byung-Nam
    • Journal of the Korea Safety Management & Science
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    • v.15 no.4
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    • pp.209-216
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    • 2013
  • By means of the model competition, this research analyzed the factor of patient management, the factor of policy support, and the factor of medical treatment system. Concretely, the factor of policy support forms a positive effects on the factor of medical treatment system. Practically, well-established healthcare policy provide and facilitate the effective medical treatment system. of the hospital. And, in the effective medical treatment system, hospitals try to develop the patient management of the chronic disease. From the empirical research, this paper concluded that the factor of medical treatment system. mediated by the factor of policy support. Also, the factor of medical treatment system promotes the development of patient management in the chronic disease.

Scale Development on Health Conservation of the Institutionalized Elderly (시설 노인의 건강보존에 관한 도구 개발)

  • Sung, Ki-Wol
    • Journal of Korean Academy of Nursing
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    • v.35 no.1
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    • pp.113-124
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    • 2005
  • Purpose: The purpose of this study was to develop a health conservation scale with high validity and reliability for institutionalized elderly. Method: The process of development of this scale was as follows. A conceptual framework composed of 4 phases of health conservation of institutionalized elderly was identified based on the literature review with elderlies and discussions with experts in health conservation. A total of 75 items, on a 4-point scale were developed. Through reliability testing and factor analysis, 57 preliminary items were selected. By means of internal consistency of the 57 items, 18 items whose inner-items correlation coefficient was below .40 were deleted. Through factor analysis, 2 items whose factor loading was below .40 were deleted. Finally 37 items remained. To verity the 37 items, factor analysis, reliability testing, and correlation was done. Data were collected from 207 institutionalized elderly subjects in Daegu, Kyungpook, Busan, and KyungNam Province from August. 2003 to February. 2004. Result: In the result of factor analysis of the 37 items, 4 factors were extracted. These factors were labeled as ‘personal integrity’, ‘conservation of energy', ‘structural integrity’, and ‘social integrity'. These factors included 4 phases of health conservation. Cronbach's Alpha of 37 the items was .9424 and the correlation coefficient of HPLP was .723. Conclusion: The researchers recommend the following: An explorative study on the variables related to health conservation is needed for criterion validity of this scale. Studies on health conservation of different age groups, and subjects are needed for verification.

Development of Elderly Meaning in Life (EMIL) Scale (노인의 생의 의미 측정 도구 개발)

  • 최순옥;김숙남;신경일;이정지;정유진
    • Journal of Korean Academy of Nursing
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    • v.33 no.3
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    • pp.414-424
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    • 2003
  • Purpose: The purpose of this study was to develop elderly meaning in life scale with high validity and reliability. Method: The process of development of this scale were as follows. A conceptual framework composed of 4 phases of meaning in life of elderly was identified based on the literature review and interviews with elderlies and discussion with experts in meaning in life. Total 62 items, 4-points scale were developed. Through reliability testing, factor analysis, 40 preliminary items were selected. By means of internal consistency of 40 items, 2 items whose inner-items correlation coefficient was below .30 were deleted. Through factor analysis 1 item whose factor loading was below .30 was deleted. Finally 37 items were remained. To verify 37 items, factor analysis, reliability testing, LISEREL were done. Data were collected from 320 elderly subjects in Busan-KyungNam and Jeonla Province from May to June in 2002. SPSS WIN. 10.0 Program was used. Result: The result of factor analysis of 37 items, 8 factors were extracted. These factors were labeled as ‘self- awareness and self-acceptance’, ‘contentedness with life’, ‘purpose in life’, ‘love in family’, ‘role awareness’, ‘futuristic aspiration’, ‘commitment’, and ‘experience of love’. These factors included 4 phases of the meaning in life. Cronbach's Alpha of 37 items was .908 and correlation coefficient of PIL was .75. Conclusion: The researchers recommend the follows: The explorative study on the variables related to meaning in life are needed for criterion validity of this scale. The studies on meaning in life of different age groups, subjects are needed for reverification.

Development of An Inventory to Classify Task Commitment Type in Science Learning and Its Application to Classify Students' Types

  • Kim, Won-Jung;Byeon, Jung-Ho;Kwon, Yong-Ju
    • Journal of The Korean Association For Science Education
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    • v.33 no.3
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    • pp.679-693
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    • 2013
  • The purpose of this study is to develop an inventory to classify task commitment types of science learning and to classify highschool students' task commitment types. Firstly, inventory questions were designed following the literature analysis on the task commitment components which involve self confidence, high goal setting, and focused attention. Prototype inventory underwent the content validity test, pilot test, and reliability test. Through these steps, final inventory was input to 462 high school students and underwent the factor analysis and cluster analysis. Factor analysis confirmed three components of task commitment as the three factors of inventory questions. In order to find how many clusters exist, factors of developed inventory became new variables. Each factor's factor mean was calculated and served as the new variable of the cluster analysis. Cluster analysis extracted five clusters as task commitment types. The 5 clusters were suggested by the agglomarative schedule and dendrogram gained from a hierarchical cluster analysis with the setting of the Ward algorithm and Squared Euclidean distance. Based on the factor mean score, traits of each cluster could be drawn out. Inventory developed by this study is expected to be used to identify student commitment types and assess the effectiveness of task commitment enhancement programs.

Study of the Measurement of Young's Modulus and Loss Factor for a Viscoelastic Damping Material Using a Multi Degree of Freedom Curve Fitting Method and RKU Equation (다자유도 곡선 맞춤법과 RKU 기법을 이용한 점탄성 감쇠재의 탄성 및 손실계수 추정방법 연구)

  • Min, Cheon-Hong;Park, Han-Il;Bae, Soo-Ryong;Jeon, Jae-Jin
    • Journal of Ocean Engineering and Technology
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    • v.25 no.1
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    • pp.67-72
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    • 2011
  • Offshore structures, such as a platform, a buoy, or a floating vessel, are exposed to several dynamic loads, and viscoelastic damping material is used to reduce the vibration of offshore structures. It is important to know the properties of viscoelastic materials because loss factor and Young's modulus of the viscoelastic damping material are dependent on frequency and temperature. In this study, an advanced technique for obtaining accurate loss factor and Young's modulus of the viscoelastic damping material is introduced based on a multi degree of freedom curve-fitting method and the RKU (Ross-Kerwin-Ungar) equations. The technique is based on a modified experimental procedure from ASTM E 756-04. Loss factor and Young's modulus of the viscoelastic damping material are measured for different temperatures by performing the test in a temperature-controlled vibration measurement room where temperature varies from 5 to 45 degrees Celsius.

Analysis on the View Factor of Data Storage and Handling Units's Radiators (자료처리/저장장치 방열판의 View Factor 분석)

  • Hwang, Inyoung;Shin, Somin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.45 no.8
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    • pp.678-685
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    • 2017
  • The radiator of the data storage and handling units onboard the earth observation satellite is a groove-type radiator covered with a shield because of the periodic high heat dissipation and design characteristics of arrangement and mountability of the unit. The effect of the groove-type radiator and that of the shield versus plane radiator were verified through the thermal vacuum test. Through the test result, the temperatures of the radiator and the heat exchange due to the view factor were analyzed by using the analytical method. Conclusively the thermal performance of the shield dissipation plate was verified.

Serum Levels of Insulin-Like Growth Factor-I in Flounder, Parlichthys olivaceus (넙치 (Parlichthys olivaceus) 혈액중 Insulin-like growth factor-I의 함유수준)

  • NAM Taek-Jeong;PARK Kie-Young;LEE Young-Don;KIM Yong-Uk
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.29 no.2
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    • pp.150-156
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    • 1996
  • Insulin-like growth factor-1 (IGF-I) is a mitogenic peptide with molecular mass of 7kDa. It is produced mainly in the liver and has important functions in the regulation of development and somatic growth. Recently, several investigations were undertaken to examine the biological actions and structures of IGF-I in fish. In this study, the serum levels of IGF-I were estimated from flounder, Parlichthys oilvaceus, before, during and after fasting, and the levels were accounted for 47 ng/ml, 40 ng/ml and 45 ng/ml, respectively. These results suggest that food deprivation primarily reduces IGF-I level in the blood.

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Development of a Questionnaire to Measure Family Stress among Married Working Women (가족스트레스 측정 도구 개발 - 기혼 여성근로자를 대상으로 -)

  • Kim Gwang-Suk;Cho Won-Jung
    • Journal of Korean Academy of Nursing
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    • v.36 no.5
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    • pp.761-769
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    • 2006
  • Purpose: Even though a number of studies have suggested that appropriate measuring instruments of family stress for working women have to be developed, the validity and reliability of the instruments used have not been consistently examined. The purpose of the present study was to develop a sensitive instrument to measure family stress for married working women, and to test the validity and reliability of the instrument. Method: The items generated for this instrument were drawn from a comprehensive literature review Twenty four items were developed through evaluation by 10 experts and twenty one items were finally confirmed through item analysis. Psychometric testing was preformed and confirmed with a convenient sample of 240 women employed in the industrial sector. Result: Four factors evolved by factor analysis, which explained 50.5% of the total variance. The first factor 'Cooperation' explained 28.1%, 2nd factor 'Satisfaction with relationships' 10.6%, 3rd factor 'Democratic and comfortable environment' 6.3%, and 4th factor 'Disturbance of own living' 5.5%, Cronbach's coefficient of this instrument was 0.86. Conclusion: The study supports the validity and reliability of the instrument.

Development of Medical Service Scale (의료서비스 척도 개발)

  • Nam, Seung-Kyu;Woo, Hoon-Shik;Kim, Young-Il;Cho, Chung-Sik
    • Journal of Haehwa Medicine
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    • v.22 no.2
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    • pp.143-154
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    • 2014
  • Objective : The purpose of this study is to establish a concept called as 'medical service' newly and to develop an reliable and valid scale that measures medical service. Methods : In order to accomplish these objectives, both conceptual study and empirical study were performed. In a conceptual study, 5 core factors(doctor, medical team, medical facilities, medical process, and hospital) and 24 sub factors were extracted with assistant by 7 experts, based on antecedent studies about components of medical service. In an empirical study, data was taken from 244 adults living in Seoul and Daejeon with the conceptually founded medical service scale. Results : Results of empirical study showed reliability and validity of the medical service scale. Internal consistency coefficient showed high score of .97 and, in accordance with the conceptual study, "medical treatment factor", "appearance factor", "personal factor", "trust factor" and "dissatisfaction factor" were extracted from the data as the five main factors. Conclusions : Finally, limitations of this study and directions for further studies are discussed. Acknowledgement : This work was supported by the Daejeon University Research Grant.