• Korean Journal of Plant Resources
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• v.29 no.2
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• pp.155-162
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• 2016

Melanin is produced by melanocytes of the melanoepidermic unit and other cell types. These cells secrete and distribute the melanin pigment, which provides protection from ultraviolet radiation. In this study, the inhibitory activity against tyrosinase and melanin biosynthesis in B16F10 melanoma cells and anti-wrinkling effects on human dermal fibroblasts of Dendrobium speciosum ethanol extract were investigated. The Dendrobium speciosum extract inhibited melanin biosynthesis and tyrosinase activity in a dose-dependent manner in comparison with an untreated control group. Treatment with the Dendrobium speciosum extract suppressed α-MSH-stimulated melanogenesis in B16F10 cells and the dendrite outgrowth of melanocyte/melanoma cells. The α-MSH-induced mRNA expression of tyrosinase-related protein-1 (TRP-1), tyrosinase-related protein-2 (TRP-2) and microphthalmia-associated transcription factor (MITF) was significantly attenuated in a concentration-dependent manner by Dendrobium speciosum treatment. In addition, Dendrobium speciosum treatment increased production of type I procollagen synthesis in human dermal fibroblasts. Dendrobium speciosum ethanol extract exhibited a potent inhibitory effect on melanin biosynthesis, tyrosinase activity and increased procollagen synthesis. These results indicate that Dendrobium speciosum shows promise as an ingredient in cosmeceutical products due to its whitening and anti-wrinkle effects.

• Korean Journal of Animal Reproduction
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• v.21 no.1
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• pp.61-69
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• 1997

The present study was carried out to investigate the effects of EGF and anti-EGF on early embryonic development and hatching in mice. Developmental and hatching rates of mouse em-bryos from 2-cell to morular stage which were cultured in Ham's FlO medium supplemented with EGF (1-1,000 ng/ml) or anti-EGF (whole serum diluted from 1:10 to 1:1,000) were compared to those of control When mouse early 2-cell embryos were cultured in the EGF supplemented medium, blastulation was accelerated compared with control. Hatching rate was also significantly (p

• Journal of the Korean Applied Science and Technology
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• v.36 no.1
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• pp.312-323
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• 2019

This purpose of study was to influence of elementary school student's Judo gym training program on social development and life satisfaction. This study aims at providing fundamental data and information on Judo participants by studying what effects of training program characteristic on social development and life satisfaction. The survey was done through 300 copies and excluding 15 copies ran an analysis on the remaining 285(90%) copies. After question investigating the data which is collected used IBM SPSS statistics 21 and IBM AMOS 21 program, frequency analysis, Exploratory factor analysis and confirmatory factor analysis, convergent validity, discriminant validity, Cronbach's ${\alpha}$, correlation analysis, path analysis through Structural Equation Model(SEM), mediation effect analysis by Sobel test. The result of this study were as follows. First, elementary school student's Judo gym training program showed (+) effects on social development. Second, elementary school student's Judo gym training program had no effects on life satisfaction. Third, social development showed (+) effects on life satisfaction. Forth, social development showed complete mediation effect on elementary school student's Judo gym training program and life satisfaction.

• Journal of the Korean Institute of Navigation
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• v.15 no.2
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• pp.39-47
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• 1991

As per the rapid development of world economics the marine traffic volume was increased accordingly and caused frequent disasters in human lives and natural environment in the consequence of accidents. As the result of the above they started to establish Vessel Traffic System(VTS) and separation scheme in waterway from 1960' to prevent the marin traffic accident but the problem of safety at sea appears now as neither fully defined nor sufficiently analysed. At the present, the dominant factor in establishing the strategy of marine traffic has been safety of navigation concerning only with the ship, but the risk of society derives almost wholly from the nature of cargo. To measure the degree of danger for each ship there is suggested concept of safety factor numbers denoting the level of latent danger in connection with ship and her cargo. In this paper, where the strategy of VTS is put on controlling density of safety factor for control area. it suggested algorithms how to assign the vessels and also to get optimal sequence of vessels located to a sector in the sense of minimizing the passage delay. For the formulation of problem, min max and 0-1 programming methods are applied and developed heuristic algorithm is presented with numerical example to improve the efficiency of calculation.

• Journal of the Korean Society of Clothing and Textiles
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• v.24 no.4
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• pp.530-537
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• 2000

The purpose of this study is to develop the measuring tool that can grasp the relationship between body and pattern, the result can be directly digitalized and developed as the pattern as body form is. There are 6 measurements; 1) the width of front and rear neck 2) the slant degree of shoulder 3) the degree of protrusion of breasts and scapulae 4) the separation of front and rear board 5) space between body and clothes 6) vertical strand in the clothes Developed measuring tool is handy in un. in which points of body to be measured are small, and it has the capability of designing the high fitness for body. The measurer developed through this study is named as $\ulcorner$Somato-pattern Measurer$\lrcorner$, size paper is named$\ulcorner$Somato-pattern Paper$\lrcorner$and the pattern made by$\ulcorner$Somato-pattern Measurer$\lrcorner$is named$\ulcorner$Somato-pattern$\lrcorner$respectively by our team. The result of this study is thought to make a great contribution to solving the various problems which can be derived in the time of pattern design because of the difference of physical forms in the same size as well as the difference between the factor of size and that of form in body.

• Proceedings of the Korean Geotechical Society Conference
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• 2003.03a
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• pp.509-512
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• 2003

Our country is serious difference of precipitation seasonally and about 66% of yearly mean rainfall is happening in concentration rainfall form between September on June. It requires consideration because of a lot of natural disasters by this downpour are produced. Slope failure is happened by artificial factor of creation of slope according to the land development, fill slope etc. and natural factor of rainfall, topography, nature of soil, soil quality, rock floor. Usually, Direct factor of failure slope is downpour. In this study, the Slope about among 55 places happened failure by downpour investigated occurrence position, geological etc and executed and inquire into character of rainfall connected with failure slope. Among character of rainfall, executed analysis about Max. hourly rainfall and cumulative rainfall of place that failure slope is situated and grasped the geological character of failure slope. Through this, inquire to character of failure slope by rainfall and take advantage of basis study for Hazard map creation.

• Journal of the Korean Society of Food Culture
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• v.26 no.6
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• pp.673-681
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• 2011

The purpose of this study was to analyze the difference in bakery choice attributes according to consumers' general characteristics and purchasing behavior. Among 350 questionnaires distributed to bakery consumers, 277 complete questionnaires (79.1%) were analyzed. Bakery choice attributes were classified into five factors: "environment and image", "bakery product features", "location", "employee service", and "price and sales promotion"; the mean scores of these factors' importance levels were 3.59, 3.58, 3.49, 3.36, and 3.00, respectively. Males considered 'employee service' factor significantly more than did females. Further, the importance level of 'employee service' factor was significantly greater as consumer's age increased. The importance levels of 'bakery product features' and 'employee service' factors were considered significantly more by consumers who spent KRW10,000-15,000 than those who spent KRW5,000 or less. 'Price and sales promotion' was considered to be more important by consumers who obtained information from the Internet than from the TV and radio. 'Location' factor was considered to be more significant as purchasing frequency increased. Such differences in importance level of bakery choice attributes according to consumers' gender, age, job, and purchasing behavior should be considered and applied to the development of marketing strategies targeted at consumers.

• Journal of Digital Convergence
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• v.11 no.12
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• pp.237-243
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• 2013

Companies engaged in the enterprise, while still at the start will have social responsibility. But recently, more and more companies will shorten the life expectancy of a corporate environment and is also rapidly changing. In this study, the longevity of global enterprises through the company's longevity factor analysis, that has continued to gain corporate answer. DuPont's global corporate giant Siemens and the longevity of the two factors in analyzing the factors that change the business portfolio, risk management, and continuous research and development, trust management, environmental management and other factors have been described. This ongoing internal and external environment analysis and core competencies by strengthening the implementation of responsible management as the core of the upcoming general management are appearing.

• Journal of Korean Academy of Nursing
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• v.35 no.2
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• pp.362-371
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• 2005

Purpose: The aim of this study was to design and evaluate a scale for measuring reliability and validity in the field of oriental nursing education. Method: A questionnaire was administered to 495 university nursing students using a convenience sampling method. The period of time for collecting data was from September 2003 to January 2004. Result: The derived outcome tool consisted of 6 factors and 22 inquires on the basis of a conceptual frame of three domains (knowledge, attitude, and skill), As a result of the item analysis, 22 items were selected and the internal consistency alpha coefficient was .767. The value of Cronbach' Alpha of knowledge(factor 1) was .885, attitude(factor2)was .756, and skill (factor 3) was .610. The three factors accounted for $65.110\%$ of the variance in the total scale. Addressing the explanatory variance of each domain Cognitive domain was $22.477\%$, affective domain was $20.543\%$, and psychomotor domain was $17.090\%$. Conclusion: Further studies need to be done to verify educational evaluation and apply our outcomes to oriental nursing education.

• Journal of Korean Academy of Nursing
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• v.35 no.3
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• pp.503-513
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• 2005

Purpose: The purpose of this study was to explore the structure and characteristics of nursing college students' personality-based career attitudes. Method: A Q-methodology was used to identify factors in nursing students' personality-based career attitudes. A Q sample was collected from in-depth and objective interviews and literature reviews. A P sample consisted of 27 nursing students. Result: Results revealed three factors: Deliberateness-oriented, Positive-oriented, and Negative-oriented. The 'Deliberateness-oriented' factor was characterized by preference of logical and objective ways in evaluation and trying to seek deep relationships with only a small number of people. The 'Positive-oriented' factor showed creative, autonomous and sociable traits and put value on extensive interpersonal relations. The 'Negative-oriented' factor focused on possibility and enjoyed artistic actions. All 3 factors were negative in NGO or political activities. Conclusion: Based on this result, curriculum development for nursing students should give students a variety of experiences. These findings will be the basic data for finding appropriate positions within the work place for nursing students and help them select appropriate careers for their own personality types.