• Title/Summary/Keyword: Development Guideline

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Design and Implementation of A Real Time Process Management System for Telecom Operations and Management (통신망 운용관리를 위한 실시간 프로세스 운용관리 시스템의 설계 및 분석)

  • Chang, Byeong-Yun;Park, Byung-Joo;Hwang, Seung-June
    • Journal of Intelligence and Information Systems
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    • v.15 no.3
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    • pp.103-118
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    • 2009
  • To face with the fast and ever changing telecommunication environments, we need a real time process management system that can detect abnormal events in real time and warn the suspicious events to operations personnel. Additionally, a real time process management system can be adapted fast to various services that are developed by telecom companies. In this paper we develop a real time process management system to monitor and analyze telecom operations and management processes in real time. Toward this, we design application and database architectures of telecom operations and management processes based on Enhanced Telecom Operations Map (eTOM) that is business process framework in telecommunication operations and management field and recognized as an international standard in ITU-T M.3050. With these application and databasearchitectures we implement eight main functions for the real time process management system based on service oriented architecture. Therefore, new services can be applied to these functions fast. Also, the functions can detect abnormal event fast. Finally, since the functions are developed along with the international standard, the system has the flexibility for the development in various situations. Overall, this research can be a good guideline of developing a process management system regarding the telecom operations and management field or other fields that need to manage the processes in real time.

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Development of an Alternative Analytical Method without Related Substance Reference Standards for Fenofibrate in Korean Pharmacopoeia (페노피브레이트 유연물질 표준품 대체시험법 개발)

  • Kim, Jung Hyun;Kim, Min Young;Kwon, Eun Kyung;Lee, Kwang Moon;Choi, Don Woong
    • YAKHAK HOEJI
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    • v.59 no.3
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    • pp.98-106
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    • 2015
  • Analytical method for related substances can be categorized into two methods depending on the necessity of reference standard (RS). The analytical method of related substances with RS is fast and accurate, but it's very expensive and technically difficult to synthesize RS due to their complicated structure. Another method is using relative retention time (RRT) and relative response factor (RRF) which are already validated with RS. Validation of this method is not easy and time consuming, but once it has been developed, it can save cost and time. In this study, we developed the analytical method for related substances of fenofibrate using RRT and RRF. We validated the method by evaluating specificity, linearity, accuracy and precision according to the "Manual for Guideline Application for Validation of Analytical Procedures" of MFDS. Also, we calculated RRT and RRF between fenofibrate and fenofibrate related substances. The results of this study showed high specificity for fenofibrate and fenofibrate related substances. Correlation coefficient(r) of all substances were more than 0.99, and the recovery of fenofibrate, fenofibrate related substance I, II and III were 99.44%, 100.84%, 99.14% and 101.58%, respectively. Precision of fenofibrate and its related substances were ranged between RSD 0.29% and 0.93%. Quantification limits of fenofibrate, fenofibrate related substance I, II and III were determined to be $0.03{\mu}g/ml$, $0.05{\mu}g/ml$, $0.04{\mu}g/ml$ and $0.02{\mu}g/ml$, respectively by confirming signal to noise ratio of each chromatogram. The RRT for fenofibrate related substance I, II and III were determined to be 0.35, 0.41 and 1.34, respectively. Also, the RRF for fenofibrate related substance I, II and III were determined to be 1.28, 0.98 and 0.79, respectively. The developed method was applied to determine contents for fenofibrate related substances in commercial fenofibrate (active pharmaceutical ingredient). As a result, developed analytical methods of related substances will be used for revising the monograph of fenofibrate in Korean Pharmacopoeia revision and contribute quality control of drugs by improving cost and time consuming problem of RS.

Persistent Organic Pollution and Arsenic Contamination in Asia Pacific Water: Case Study of Emerging Environmental Problems in Vietnam

  • Pham, Viet.H.
    • Journal of Wetlands Research
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    • v.9 no.1
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    • pp.79-89
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    • 2007
  • This paper provides a comprehensive overview of the present status of several environmental problems caused by emerging toxic substances such as persistent organic pollutants (POPs), endocrine disrupting chemicals (EDCs), and arsenic in various environmental media in Vietnam. Monitoring data reported during the 1990s demonstrated elevated contamination of DDTs in most of these compartments in Vietnam. Studies in frame of the Asia-Pacific Mussel Watch Program revealed that fish, mussels and resident birds from Vietnam contained higher concentrations of DDTs as compared to other countries in region, suggesting the role of Vietnamese environment as a significant emission source of DDT in the Southeast Asian region. The estimated dietary intakes of PCBs and DDTs for Vietnamese were relatively high among Asian developing countries, suggesting potential risk for humans posed by thesechemicals. Widespread contamination of some endocrine active compounds such as alkylphenols and phthalates was observed at various sites along the coasts of northern and middle Vietnam. The presence of significant source of bisphenol-A along Red River estuary was revealed with the concentrations comparable to those reported for developed nations. A case study on seasonal variation of alkylphenols and phthalates in surface water of river delta and estuary of north and middle Vietnam indicated the differences in distribution of these compounds between dry and rainy seasons. Higher concentrations of alkylphenols and phthalates were found in dry season in estuary; while the contrasting pattern was observed in the river delta, showing elevated residues in rainy season. This result suggests the different behavior of alkylphenols and phthalates in river delta and coastal environment. From ecotoxicological perspectives, concentrations of bis-phenol A and di(2-ethylhexyl)phthalates [DEHP] in surface water from some locations in Vietnam exceeded the guideline values for Ecotoxicological Effects and the Environmental Risk Limit, respectively, suggesting potential for toxic implications on aquatic wildlife. Widespread and elevated arsenic contamination was discovered inour recent surveys in groundwater in a large area of suburban areas of Hanoi city, the capital of Vietnam. The most recent investigation in 4 villages showed about more than 50 % of groundwater samples contained As concentrations exceeding 50 g/L (the WHO and Vietnamese standard). In particular, in Son Dong villages, 58 % of samples analyzed contained As concentrations higher than 200 g/L. Good correlations were found in As concentrations in water and hair and urine of peoples in corresponding families, suggesting the chronic exposure to As by people living in As-contaminated ground water areas. In Son Dong village, As levels in hair (mean: 1.7 mg/kg dry wt) and urine (g/g creatinine) exceeding the reference values recommended by WHO, suggesting potential for human risk posed by long term accumulation of As in human body. Future studies should be focused on the time trends of POPs and EDCs in biota in Vietnam in order to predict future trend of contamination and to reveal new clues for understanding possible toxic impacts on aquatic organisms. The issues of arsenic contamination in groundwater and their chronic toxic implications on human health should be systematically investigated in the future.

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Advances in Radiation Oncology in New Millennium in Korea (21세기 방사선종양학의 전망:최근의 진보와 한국에서의 발전)

  • Huh, Seung-Jae;Park, Chan-Il
    • Radiation Oncology Journal
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    • v.18 no.3
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    • pp.167-176
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    • 2000
  • The objective of recent radiation therapy is to improve the quality of treatment and the after treatment quality of life. In Korea, sharing the same objective, significant advancement was made due to the gradual increase of patient number and rapid increase of treatment facilities. The advancement includes generalization of three-dimensional conformal radiotherapy (3D-CRT), application of linac-based stereotactic radiosurgery (SRS), and furthermore, the introduction of intensity modulated radiation therapy (IMRT). Authors in this paper prospectively review the followings: the advancement of radiation oncology in Korea, the recent status of four-dimensional radiation therapy, IMRT, the concept of the treatment with biological conformity, the trend of combined chemoradiotherapy, the importance of internet and radiation oncology information management system as influenced by the revolution of information technology, and finally the global trend of telemedicine in radiation oncology. Additionally, we suggest the methods to improve radiotherapy treatment, which include improvement of quality assurance (QA) measures by developing Koreanized QA protocol and system, regional study about clinical protocol development for phase three clinical trial, suggestion of unified treatment protocol and guideline by academic or research societies, domestic generation of treatment equipment's or system, establishment of nationwide data base of radiation-oncology-related information, and finally patterns-of-care study about major cancers.

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Process Alignment between MND-AF and ADDMe for Products Reusability (산출물 재사용성을 위한 MND-AF와 ADDMe 프로세스 정렬)

  • Bu, Yong-Hee;Lee, Tae-Gong
    • Journal of the military operations research society of Korea
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    • v.32 no.2
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    • pp.131-142
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    • 2006
  • Nowadays, most enterprises have introduced both EA methodology to optimize an entire enterprise and CBD methodology to improve a software reusability. The Korea Government not only have developed many EA guiding products such as EA framework, Reference Model, Guideline, etc. but also have instituted a law to optimize a government-wide enterprise. The Minister of National Defense(MND) have developed the MND-AF as a standard methodology for EA and the ADDMe as a standard methodology for CBD. But it is possible to develop products of WD-AF and ADDMe redundantly because the process of MND-AF and ADDMe is not quitely aligned. The purpose of this paper is to present a scheme that ADDMe can reuse the artifacts of MND-AF by analyzing the relationships between two processes. In order to identify the relationships between two processes, we first identify the relation of a 'definition' part of two processes and then identify the relation of an 'attribute' part based on the relation of a 'detailed definition' part. As a result we found that 113 attributes of MND-AF are related to 49 attributes of ADDMe. Therefore the proposed study will decrease the development cost and time and will be a good example for aligning the process of EA and CBD methodology.

Development of Knee Pain Diagnosis Questionnaire and Clinical Study of Diagnostic Correspondent Rate (슬통 진단용 설문지개발 및 진단 일치도 평가연구)

  • Hwang, Ji-Hoo;Kim, Yu-Jong;Kim, Eun-Jung;Lee, Cham-Kyul;Lee, Eun-Yong;Lee, Seung-Deok;Kim, Kap-Sung
    • Journal of Acupuncture Research
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    • v.29 no.5
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    • pp.61-74
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    • 2012
  • Objectives : This study is perfomed for preparation of oriental medicine clinical guidelines for drawing up the standards of oriental medicine demonstration and diagnosis classification about the knee pain. Methods : Statistical analysis about Crane's-knee wind(鶴膝風), arthralgia syndrome(痺症), knee injury(膝傷), gout arthritis(痛風), Youk jeol poung(歷節風) classified experts' opinions about knee pain patients by Delphi method is conducted by using oriental medicine diagnosis questionnaire. The result was classified by using linear discriminant analysis(LDA), diagonal linear discriminant analysis(DLDA), diagonal quadratic discriminant analysis(DQDA), K-nearest neighbor classification(KNN), classification and regression trees(CART), support vector machines(SVM). Results : The results are summarized as follows. 1. The result analyzed by using LDA has a hit rate of 81.65% in comparison with the original diagnosis. 2. The result analyzed by using DLDA has a hit rate of 63.3% in comparison with the original diagnosis. 3. The result analyzed by using DQDA has a hit rate of 65.14% in comparison with the original diagnosis. 4. The result analyzed by using KNN has a hit rate of 74.31% in comparison with the original diagnosis. 5. The result analyzed by using CART has a hit rate of 75.23% in comparison with the original diagnosis when the test of selected 13 significant questions based on analysis of variance was performed. 6. The result analyzed by using SVM has a hit rate of 87.16% in comparison with the original diagnosis. Conclusions : Statistical analysis using oriental medicine diagnosis questionnaire on knee pain generally turned out to have a significant result.

CLINICO-STATISTICAL ANALYSIS OF POSSIBLE FACTORS LEADING TO PROBLEMS IN THE SURGICAL TREATMENT OF UNILATERAL MANDIBLAR CONDYLE FRACTURES (편측 하악 과두골절의 관혈적 치료에 있어서 예후에 영향을 줄 수 있는 인자들에 관한 임상 통계학적 연구)

  • Sung, Hun-Mo;Lee, Dong-Keun;Min, Seung-Ki;Oh, Seung-Hwan;Jang, Kwan-Sik
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.23 no.1
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    • pp.31-39
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    • 2001
  • The purpose of this study is to reveal the factors leading to the problem of unilateral condylar fractures and suggest a treatment guideline of treatment for good prognosis in surgical treatment. The factors can be age, sex, fracture site, degree of displacement, posterior occlusion loss, post-operative alteration of condylar head position, post-operative condylar head resorption, and maxillomandibular fixation period. One hundred and eleven patients with unilateral condylar fractures, who were treated by surgical method from 1990 Feb. to 2000 Feb., were studied. Minimum follow-up period was 6 months. The results were as follows ; 1. In the age group of $41{\sim}60$, females had significantly higher complication rate than males, therefore we must be careful about treatment of female in this age group 2. In level I fractures of the mandibular condyle, because there were abundant complications when the patients were treated with fragment removal, conservative treatment is recommended over the surgical approach. 3. There were no differences in the complication rate, in the level II, III fractures. but were severe complications in the cases of patients treated by Dr.Nam's method or fragment removal. Therefore, open reduction and internal fixation is recommended over Dr.Nam's method or fragment removal. 4. In level IV fractures, open reduction and internal fixation is recommended 5. Although there was a higher complication rate depending on the degree of deviation, there was no correlation between the degree of deviation and development of complications in each level of fracture 6. Because the complication rate was higher in cases of condylar resorption, vertical dimension loss, and alteration of condylar head position, we must make an effort to prevent such complications during treatment

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Longitudinal measurements of tooth mobility following orthodontic treatment (교정치료 후 치아동요도 감소에 대한 종단적 계측연구)

  • Hwang, Hyeon-Shik;Kim, Wang-Sik;Kim, Jeong-Moon;Mcnamara, James A. Jr.
    • The korean journal of orthodontics
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    • v.40 no.1
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    • pp.34-39
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    • 2010
  • Objective: The aim of the present study was to evaluate the changes in tooth mobility following orthodontic treatment and to obtain information regarding the guideline of retainer wear duration during the post-treatment period. Methods: The sample consisted of twenty patients who had been treated with edgewise appliances. The mobility of the maxillary teeth from the central incisor to the first molar was measured bilaterally by way of the $Periotest^{(R)}$, a non-invasive, electronic device that provides an objective measurement of the reaction of the periodontium to a defined impact load. Tooth mobility was monitored at the time of the removal of the orthodontic appliances and subsequently at three-month intervals during the two years following appliance removal. Results: Tooth mobility decreased rapidly for the first six months and then decreased at a slower rate during the next six months; no statistically significant decrease in mobility was observed during the second year following appliance removal. Conclusions: The results of the present study suggest that adequate tooth stabilization is critical during the first six months following appliance removal and that continued wearing of retainers is recommended at least until twelve months after the completion of orthodontic treatment.

A Study about Search Engine Interface Design including User's Search Goal (사용자의 검색 목적을 포함한 검색엔진 인터페이스 디자인에 관한 연구)

  • Jin, Beom-Suk;Ji, Yong-Gu
    • The Journal of Society for e-Business Studies
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    • v.13 no.4
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    • pp.111-124
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    • 2008
  • The development in information technology allowed most of the information around us into digital information, in other words, a database. The innovation increased the accessibility and helped this society change into an informational age. However, there is a shortcoming of this open source as the users have difficulty in assorting the information that s/he needs and realizing if the information provided is important. Therefore, the need for search engine has risen in such a way to increase the accessibility and facilitation of information provided to the users through searching the necessary information in the database by an easy and accurate way. This aim of study should propose the important design attribute to increase the utilization of search engine through relationship analysis between purpose of user and interface design factors of search engine. In other words, these attributes, as design guideline, could apply to the search engine interface design considering of user's search goal. For this, the purpose in using the search engine and types of search engine interfaces were categorized and correlated the relationships. The search engine interface suggested from the result provides interface that allows efficient search for desired information and embrace a variety in users, eventually increasing the usability in search engine.

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The Process of Brand Building: Seoul city 'itourseoul' brand case study (서비스 브랜드 구축과정: 서울시 '아이투어서울(itourseoul)' 브랜드 구축사례)

  • Lee, Jaejin;Yoon, Sung-Yong
    • Journal of the Korea Society of Computer and Information
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    • v.18 no.7
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    • pp.125-137
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    • 2013
  • Seoul city provided u-tourism services for inbound tourists' convenience. These services began in April, 2010 and were completed in advanced way by the end of 2011. Seoul city developed a brand fit to the new services simultaneously for communicating it. Recently, there are so many cities in the world that steadily try to give favorable impression and images to people. In the study, we analyze the process of brand building to present a guideline for city brand and tourism service brand building. The study includes a series of brand making process such as environment of brand, customer analysis, design of brand platform, brand hierarchy, visualization of various brand factors, strategies of operation and performances of brand awareness and draw a conclusion and suggest an advice. As for implication, the study shows the necessity of service brand launching plus Seoul official brand(Hi, Seoul), the service brand including ubiquitous concept, development of brand factors with complementarity and observation of systematical methodology.