• Title/Summary/Keyword: Development

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A Comparative Study on Rural Development of Korea and EU (한국과 EU의 농촌개발의 비교)

  • Lim, Hyung-Baek;Cho, Joong-Koo
    • Journal of Korean Society of Rural Planning
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    • v.10 no.2 s.23
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    • pp.25-34
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    • 2004
  • The objectives of this study were to compare rural development of Korea and EU. According to its traits the peroids of rural development of Korea can be divided into low periods. According to its memberships and traits the periods of rural development of EU can be divided into low periods. There are many similarities between Korea and EU in agricultural situation and rural development. EU introduced multifunctionality of agriculture in 1980s and adopt strong policy to support that in 1990s. And EU made a effort sustainable rural development, integrated rural development and balanced regional development. Recently Korea not only maintain agricultural expanisionism but also pay attention to multifunctionality of agriculture. But rural development of Korea still in the stage of physical planning and agricultural expanisionism. So it leaves much room for improvement to rural development of Korea in rural development regulation, unifying theme, detail planning, integration among policies, balanced regional development, etc.

The Study for Correlation Among Auditory Development and Language Development of Children with Hearing Impairment (청각장애 아동의 청능발달과 언어발달간의 상관관계 연구)

  • Park, Sang-Hee;Kwon, Young-Ju
    • Speech Sciences
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    • v.10 no.4
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    • pp.255-261
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    • 2003
  • The purpose of this study was to investigate correlation of auditory development and language development of children with hearing impairment Eighteen subjects with severe or profound hearing loss participated in this study. They were 22-to 55-month-olds who had hearing parents with no additional disabling conditions. The test material was the Meaningful Auditory Integration Scale (MAIS) and MacArthur Communicative Development Inventory-Korea (MCDI-K). A Pearson Correlation Coefficient was determined through a statistical analysis. The results followed as; firstly there was a strong correlation between auditory development and receptive language development. Secondly, there was a strong correlation between receptive language development and expressive language development. Finally, there was a strong correlation between auditory development and education onset time. Therefore, auditory training is important method for auditory rehabilitation and education onset time is important variation for auditory development.

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Geft is dispensable for the development of the second heart field

  • Fan, Xiongwei;Hou, Ning;Fan, Kaiji;Yuan, Jiajia;Mo, Xiaoyang;Deng, Yun;Wan, Yongqi;Teng, Yan;Yang, Xiao;Wu, Xiushan
    • BMB Reports
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    • v.45 no.3
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    • pp.153-158
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    • 2012
  • Geft is a guanine nucleotide exchange factor, which can specifically activate Rho family of small GTPase by catalyzing the exchange of bound GDP for GTP. Geft is highly expressed in the excitable tissue as heart and skeletal muscle and plays important roles in many cellular processes, such as cell proliferation, migration, and cell fate decision. However, the in vivo role of Geft remains unknown. Here, we generated a Geft conditional knockout mouse by flanking exons 5-17 of Geft with loxP sites. Cre-mediated deletion of the Geft gene in heart using Mef2c-Cre transgenic mice resulted in a dramatic decrease of Geft expression. Geft knockout mice develop normally and exhibit no discernable phenotype, suggesting Geft is dispensable for the development of the second heart field in mouse. The Geft conditional knockout mouse will be a valuable genetic tool for uncovering the in vivo roles of Geft during development and in adult homeostasis.

ZNF552, a novel human KRAB/C2H2 zinc finger protein, inhibits AP-1- and SRE-mediated transcriptional activity

  • Deng, Yun;Liu, Bisheng;Fan, Xiongwei;Wang, Yuequn;Tang, Ming;Mo, Xiaoyang;Li, Yongqing;Ying, Zaochu;Wan, Yongqi;Luo, Na;Zhou, Junmei;Wu, Xiushan;Yuan, Wuzhou
    • BMB Reports
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    • v.43 no.3
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    • pp.193-198
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    • 2010
  • In this study, we report the identification and characterization of a novel C2H2 zinc finger protein, ZNF552, from a human embryonic heart cDNA library. ZNF552 is composed of three exons and two introns and maps to chromosome 19q13.43. The cDNA of ZNF552 is 2.3 kb, encoding 407 amino acids with an amino-terminal KRAB domain and seven carboxyl-terminal C2H2 zinc finger motifs in the nucleus and cytoplasm. Northern blotting analysis indicated that a 2.3 kb transcript specific for ZNF552 was expressed in liver, lung, spleen, testis and kidney, especially with a higher level in the lung and testis in human adult tissues. Reporter gene assays showed that ZNF552 was a transcriptional repressor, and overexpression of ZNF552 in the COS-7 cells inhibited the transcriptional activities of AP-1 and SRE, which could be relieved through RNAi analysis. Deletion studies showed that the KRAB domain of ZNF552 may be involved in this inhibition.

KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1

  • Hu, Junjian;Yuan, Wuzhou;Tang, Ming;Wang, Yuequn;Fan, Xiongwei;Mo, Xiaoyang;Li, Yongqing;Ying, Zaochu;Wan, Yongqi;Ocorr, Karen;Bodmer, Rolf;Deng, Yun;Wu, Xiushan
    • BMB Reports
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    • v.43 no.1
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    • pp.17-22
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    • 2010
  • In this study, a novel member of BTB-kelch proteins, named KBTBD7, was cloned from a human embryonic heart cDNA library. The cDNA of KBTBD7 is 3,008 bp long and encodes a protein product of 684 amino acids (77.2 kD). This protein is highly conserved in evolution across different species. Western blot analysis indicates that a 77 kD protein specific for KBTBD7 is wildly expressed in all embryonic tissues examined. In COS-7 cells, KBTBD7 proteins are localized to the cytoplasm. KBTBD7 is a transcription activator when fused to GAL4 DNA-binding domain. Deletion analysis indicates that the BTB domain and kelch repeat motif are main regions for transcriptional activation. Overexpression of KBTBD7 in MCF-7 cells activates the transcriptional activities of activator protein-1 (AP-1) and serum response element (SRE), which can be relieved by siRNA. These results suggest that KBTBD7 proteins may act as a new transcriptional activator in mitogen-activated protein kinase (MAPK) signaling.

Software Development Effort Estimation for Testing Data Analysis (테스팅 데이터 분석을 통한 소프트웨어 개발 노력 추정)

  • Jung, Hye-Jung;Yang, Hae-Sool
    • The KIPS Transactions:PartD
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    • v.11D no.1
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    • pp.173-182
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    • 2004
  • The research to estimate development effort of software has been progress. But, it is not easy gain that testing data for estimating of development effort. Also, if we get the testing data, it is important that analysis testing data. In this paper, we study the data analysis of software development effort using the 789 software development projects which developed in the 1990's. Software development scale and software development team site are various. Using the characteristic of factor, we have to study characteristic of data and we estimate the development effort step by step. First, we prove the difference of development effort with the 789 project data according to development type, development environment, the development language etc. Also, we execute the crosstabs analysis that team site and function point.

The Marriage Stewardship and the Role and Status of Social Development Network in Singapore (결혼 책임주의와 싱가포르 Social Development Network의 역할과 위상)

  • Kim, Myung-Hee
    • Journal of the Korea Convergence Society
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    • v.9 no.1
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    • pp.143-149
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    • 2018
  • This paper focuses on how Singapore has adopted the 'Marriage Promotion Policy' for resolving the low birthrate and how it has been using the Social Development Network (SDN) to cope with the problem of low fertility. Social Development Network is an organization that shows Singapore's national stewardship to marriage, and has developed from the beginning to the social phenomenon of increasing number of highly educated women and decreasing fertility. The predecessor of Social Development Network is 'Social Development Unit' (SDU), absorbed the 'Social Development Service' (SDS) that was launched later, and reborn as Social Development Network in 2009. At its inception, Social Development Network has been recruiting and organizing its own memberships without the help of commercial marriage agencies, and since 2006 has been dedicated to delegating dating and matchmaking services to private companies and supporting projects. The purpose of this paper using literature analysis is to analyze the status and role of Social Development Network from the theoretical point of view of marital stewardship to the present, and to suggest meaningful implications for Korea which has the same social experience.

A Preliminary Study on the Development of Infant-Toddler Developmental Scale : 1 to 36 Months (영유아발달 척도의 개발을 위한 기초 연구: 1-36개월 영유아를 중심으로)

  • Song, Jin-Suk
    • Korean Journal of Human Ecology
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    • v.9 no.4
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    • pp.405-419
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    • 2000
  • The purpose of this study was to develop a Korean infant-toddler developmental scale and to examine the demographic variables and infant-toddler development. The subjects were 167 mothers who have infant and toddler from 1 to 36 months of age in Seoul, Daejeon, Chungju, Yeasan, and llsan in Korea. The subscales consisted of language development, social and emotional development, physical development, and cognitive development. The significant variables which are influenced the infant-toddler development were age of infant-toddler and age of father.

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A Study on the Balance of Regional Development and Policy Tasks for Rural community Development (지역균형 발전과 농촌 지역사회개발정책)

  • Kim, Tae-Ho
    • Journal of Agricultural Extension & Community Development
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    • v.3 no.2
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    • pp.233-246
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    • 1996
  • Reviewing the meaning aid task of balance of regional development, this papa examines the causes of the underdevelopment of rural areas in relation to the urbanization process, probes the concept, principle and necessity of rural community development, and suggests the policy tasks for rural community development in the perspective of regionally balanced development. Since 1960's, Korea has pursued a growth-oriented economic policy. The focus on the aggregated growth, however, has resulted bo invite some regional disparity problems. In the process of development, regional disparity problems were quite a large rural areas compared with urban areas relatively. The under-development of rural areas is deeply correlated with the overcrowding (or overconcentration) phenomena of urban(or metropolitan) areas. The urban-biased policy is the primary cause of the deepening regional imbalance structure between urban and rural areas. The inter-regions equitable and well-balanced development is one of the national policy issues by which the government is confronted, since the issue is closely related with national quality of life. Main three policy tasks for rural community development were 'the new paradigm of development policy' , 'local-oriented policy' and 'human-oriented policy'.

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