• Title/Summary/Keyword: Determination method

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Two Bayesian methods for sample size determination in clinical trials

  • Kwak, Sang-Gyu;Kim, Dal-Ho;Shin, Im-Hee;Kim, Ho-Gak;Kim, Sang-Gyung
    • Journal of the Korean Data and Information Science Society
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    • v.21 no.6
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    • pp.1343-1351
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    • 2010
  • Sample size determination is very important part in clinical trials because it influences the time and the cost of the experimental studies. In this article, we consider the Bayesian methods for sample size determination based on hypothesis testing. Specifically we compare the usual Bayesian method using Bayes factor with the decision theoretic method using Bayesian reference criterion in mean difference problem for the normal case with known variances. We illustrate two procedures numerically as well as graphically.

Position Determination Using Multi-lateration Method (멀티레터레이션법을 이용한 절대간섭계의 점광원 위치 결정법)

  • Kim, Byoung-Chang
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.9
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    • pp.856-860
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    • 2006
  • A CCD camera is used to determine the position of the point sources that influence the measurement accuracy in the absolute interferometer. The principle of determination method is based on the GPS in which the position is determined by more than 3 distance information from the known positions. Two-dimensional array of photo-detectors in the CCD camera is used as known positions. Performing optimization of the cost function constructed with phase values measured at each pixel on the CCD camera, the position coordinates of each source is precisely determined.

Rapid Determination of Cesium-137 ($Cs^{137}$의 迅速定量法)

  • Kim, Tai-Soon;Park, Tai-Won;Lee, Chun-Yung;Seu, Kyung-Sook
    • Journal of the Korean Chemical Society
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    • v.5 no.1
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    • pp.29-32
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    • 1961
  • Two methods for the determination of Cesium-137 in various foods(ashes) were compared. The one comprises two steps, the first being the separation of alkalies as cobaltinitrites or perchlorates by the radiochemical method, and the second being the measurement of photopeak area due to the presence of Cs-137 by the use of scintillation spectrometer. The other method is the direct subjection of ash samples to the spectrometry without the radiochemical separation. The combined contribution of K-40 and Rb-87 to the spectrum was not found on account of the difference in energies of these nuclides. These two methods gave, a good agreement in the determination of Cs-137 in 50-100g ash samples of vegetables or cereals under investigation.

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Determination of Vitamin C in Chewing Gum Using Extraction by Tetrahydrofuran (테트라하이드로퓨란에 의한 추출방법을 이용한 츄잉검의 비타민 C 정량)

  • Roh, Hoe-Jin;Kim, Pil;Park, Cheon-Ho;Lee, Kee-Jung;Noh, Bong-Soo;Choi, Jin-Hwan
    • Korean Journal of Food Science and Technology
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    • v.31 no.6
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    • pp.1484-1487
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    • 1999
  • Extraction is the most important and tedious step to determine water-soluble vitamin C in water-insoluble chewing gum. For the rapid determination of vitamin C in chewing gum, a new method of dispersion in tetrahydrofuran(THF) was performed. Vitamin C was easily extracted from gum base using THF The content of vitamin C in chewing gum was rapidly quantified with high reliability by an enzymatic method using a chewing gum sample dispersed in tetrahydrofuran.

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AN APPLICATION OF THE DETERMINATION METHOD FOR SOIL PARAMETERS WITH THE DESIGN CODE FOR PORT AND HARBOUR FACILITIES IN JAPAN

  • Watabe, Yoichi;Nozaki, Ikuro;Tanaka, Masanori;Kwon, Oh-Kyun
    • Proceedings of the Korean Geotechical Society Conference
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    • 2010.09c
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    • pp.31-36
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    • 2010
  • This paper introduces a practical determination method for soil parameters adopted in the new performance based design code for port and harbour facilities in Japan. In the new port-design code, the depth profile of the derived values is modeled as the profile of the estimated values so as to be either the mean value or the regression line, then the correction factors are multiplied to the estimated value according to the coefficient of variation (if COV > 0.1) and the number of the data entries (if n < 10). The new port-design code is applied to the unconfined compression test results for the Hiroshima Port clay in order to evaluate the undrained shear strengths. From the discussion, it is emphasized that not only the statistic treatment but also the engineering judgment are required in the procedure of the soil parameter determination for the reliability design.

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A Determination of the Reference Model for the Model Following System using an Expert System (전문가 시스템을 이용한 모델 추종 시스템의 기준 모델 선정)

  • Moon, Dong-Wook;Hwang, Young-Moon;Kang, Young-Ho;Lee, Hoo-Min;Kim, Lark-Kyo
    • Proceedings of the KIEE Conference
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    • 1996.07b
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    • pp.1069-1072
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    • 1996
  • In modern control engineering, the model following system is a typical method. The model following system's performance is due to algorithm of control law, accuracy of modeling to the plant, and dynamics of the reference model. But the determination of the reference model depends on knowledge of an expert. Using an expert system, the determination method of the reference model was proposed in this paper. So, the reference model can be selected by user who has no Knowledge of dynamics and parameters.

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Determination of Monocrotophos Residues by HPLC

  • Lee, Young-Deuk;Kwon, Chan-Hyeok
    • Korean Journal of Environmental Agriculture
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    • v.23 no.4
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    • pp.245-250
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    • 2004
  • An analytical method was developed to determine monocrotophos residues in apple, citrus, and soil using high-performance liquid chromatography (HPLC) with ultraviolet absorption detection. Monocrotophos was extracted with acetone from apple, citrus and moist soil samples. The extract was concentrated, added with saline water, and subjected to n-hexane washing to remove nonpolar co-extractives. Dichloromethane partition was then followed to recover monocrotophos from the aqueous phase. Silica gel column chromatography was employed to further purify the extract prior to HPLC determination. Reverse-phase HPLC using an oct-adecylsilyl column was successfully applied to separate and quantitate the monocrotophos residue in sample extracts at the wavelength of 230 nm. Overall recoveries of monocrotophos from fortified samples averaged $95.3{\pm}2.1%$ (n=6), $970{\pm}0.7%$ (n=6), and $92.8{\pm}4.3%$ (n=12) for apple, citrus, and soil, respectively. The proposed method was quite reproducible and sensitive enough to replace the troublesome gas-liquid chromatographic analysis for monocrotophos residues.

Precise Determination of Silicon in Ceramic Reference Materials by Prompt Gamma Activation Analysis at JRR-3

  • Miura, Tsutomu;Matsue, Hideaki
    • Nuclear Engineering and Technology
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    • v.48 no.2
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    • pp.299-303
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    • 2016
  • Prompt gamma activation analysis using a thermal neutron-guided beam at Japan Atomic Energy Agency JRR-3M was applied for the precise determination of Si in silicon nitride ceramic reference materials [Japan Ceramic Reference Material (JCRM) R 003]. In this study, the standard addition method coupled with internal standard was used for the nondestructive determination of Si in the sample. Cadmium was used as internal standard to obtain the linear calibration curves and to compensate for the neutron beam variability. The analytical result of determining Si in JCRM R 003 silicon nitride fine powder ceramic reference materials using prompt gamma activation analysis was in good agreement with that obtained by classical gravimetric analysis. The relative expanded measurement uncertainty (k = 2) associated with the determined value was 2.4%.

Automated Control Gain Determination Using PSO/SQP Algorithm (PSO/SQP를 이용한 제어기 이득 자동 추출)

  • Lee, Jang-Ho;Ryu, Hyeok;Min, Byoung-Moom
    • Aerospace Engineering and Technology
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    • v.7 no.1
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    • pp.61-67
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    • 2008
  • To design flight control law of an unmanned aerial vehicle, automated control gain determination program was developed. The procedure for determination of control gain was formulated as the control gains were designed from the optimal solutions of the optimization problem. PSO algorithm, which is one of the evolutionary computation method, and SQP algorithm, which is one of the nonlinear programming method, are used as optimization problem solver. Thru this technique, computation time required for finding the optimal solution is decreased to 1/5 of that of PSO algorithm and more accurate optimal solution is obtained.

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A Study on the Alkalimetric Titration with Gran Plot in Noncomplexing Media for the Determination of Free Acid in Spent Fuel Solutions

  • 서무열;이창헌;손세철;김정숙;엄태윤
    • Bulletin of the Korean Chemical Society
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    • v.20 no.1
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    • pp.59-64
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    • 1999
  • Based on the study of hydrolysis behaviour of U(Ⅵ) ion and major fission product metal ions such as Cs(Ⅰ), Ce(Ⅲ), Nd(Ⅲ), Mo(Ⅵ), Ru(Ⅱ), and ZR(Ⅳ) in the titration media, the performance of noncomplexing-alkalimetric titration method for the determination of free acid in the presence of these metal ions was investigated and its results were compared to those from the completing methods. The free acidities could be determined as low as 0.05 meq in uranium solutions in which the molar ratio of U(Ⅵ)/H+ was less than 5, when the end-point of titration was estimated by Gran plot. The biases in the determinations were less than 1% and about +3% respectively for 0.4 meq and 0.05 meq of free acid at the U(Vl)/H+ molar ratio of up to 5. Applicability of this method to the determination of free acid in spent fuel solutions was confirmed by the analysis of nitric acid content in simulated spent fuel solutions and in a real spent fuel solution.