• Title/Summary/Keyword: Detecting Effect

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Antioxidant effects of the Herbs Composing Yukmijihwang-tang on PC12 Cell (육미지황탕 구성약물이 PC12 세포의 산화억제에 미치는 영향)

  • Seo Young Eun;Lee Eun-A;Bae Hyun Su;Shin Min Kyu;Hong Moo Chang
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.1
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    • pp.203-208
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    • 2003
  • Antioxidant effects of Rehmannia vaporata, Discorea Radix, Corni Fructus, Hoolen, Alismatis Radix, and Mountain Cortex Radicis composing Yukmijihwang-tang were studied. The results are as follows; 1. As a result of detecting the defensive effect of each component on cell damage, only the survival rate of cells with 10 ㎎/㎖ Mountain Cortex Radicis was significantly increased. 2. Next, we examined the inhibitory effects of them on ROS occurrence. The result showed significant inhibition of ROS occurrence in cells; with 10 ㎎/㎖ Rehmannia vaporata, cells with 10 ㎎/㎖ Corni Fructus, and cells with 10 ㎎/㎖ Mountain Cortex Radicis. Since the cells with 10 ㎎/㎖ Rehmannia vaporata, however, showed significant cypotoxicity, its result is not meaningful. 3. Finally, the investigation of ROS occurrence / cell found that Corni Fructus and Mountain Cortex Radicis had significant inhibitory effect on ROS occurrence.

Toxicity Monitoring and Classification of Endocrine Disruptors using Bioluminescent Bacteria.

  • Min, Ji-Ho;Gu, Man-Bok
    • 한국생물공학회:학술대회논문집
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    • 2000.04a
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    • pp.117-120
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    • 2000
  • For detecting toxicity of endocrine disruptors (EDs), rapid, sensitive, and simple methods are needed. Therefore, in this study, a new method in which the different toxic effect of EDs can be monitored using 4 different recombinant bacteria was designed and evaluated. It was found that the recombinant bacteria could monitor the toxic effect, not estrogenic effect, due to EDCs through the measurement of bioluminescence and cell growth rate, which were shown to depend upon a form of cellular toxicity, such as DNA damage, protein damage, oxidative damage, and membrane damage. In addition, it was found that the damage done by EDCs can be divided into several groups based upon the toxic mechanisms of the EDCs

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Algorithm of Optical Camera Communications Using Rolling-Shutter Effect (롤링셔터 효과를 이용한 광학 카메라통신 알고리즘)

  • Lee, Jungho;Kim, Nayeong;Ju, MinChul;Park, Youngil
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.41 no.4
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    • pp.454-460
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    • 2016
  • Unlike conventional visible light communications (VLC) adopting photo detectors (PD), optical camera communications (OCC) employs cameras in detecting the transmitted data. Especially, the data rate of OCC can be enhanced by using the principle of rolling-shutter, which is the operating scheme of a CMOS image sensor. In this study, we consider a novel OCC system for high-speed real time video processing to transmit high speed data from LED and to acquire image utilizing rolling-shutter effect of CMOS image sensor. Also, we demonstrate the improved performance of proposed system using a test-bed.

Temperature Effect on Impedance-based Damage Monitoring of Steel-Bolt Connection using Wireless Impedance Sensor Node (무선 임피던스 센서노드를 이용한 강-볼트 접합부의 임피던스기반 손상모니터링에 미치는 온도 영향)

  • Hong, Dong-Soo;Kim, Jeong-Tae
    • Journal of Ocean Engineering and Technology
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    • v.26 no.1
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    • pp.27-33
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    • 2012
  • This paper presents the effect of temperature on the impedance-based damage monitoring of steel-bolt connections using wireless impedance sensor nodes. In order to achieve the objective, the following approaches are implemented. First, a temperature-compensated damage monitoring scheme that includes a temperature compensation model and damage detection method is described. The temperature compensation model is designed by analyzing the linear regressions between the temperatures and impedance signatures. The correlation coefficient of the impedance signatures is selected as the damage index to monitor the damage occurrence in the target structures. Second, a wireless impedance sensor node is described for the design of the hardware components and embedded software. Finally, the performance of the temperature-compensated impedance-based damage monitoring scheme is evaluated for detecting a loose bolt in the steel-bolt connections on a lab-scale steel girder under various temperatures.

Fabrication and Characterization of a Wrist Wearable Cuffless Pulsimeter by Using the Hall Effect Device

  • Lee, Sang-Suk;Choi, Jong-Gu;Son, Il-Ho;Kim, Keun-Ho;Nam, Dong-Hyun;Hong, You-Sik;Lee, Woo-Beom;Hwang, Do-Guwn;Rhee, Jang-Roh
    • Journal of Magnetics
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    • v.16 no.4
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    • pp.449-452
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    • 2011
  • A wrist wearable cuffless pulsimeter with a portable and small size apparatus using Hall effect is fabricated. The analysis of the pulse wave measured by the testing product of pulsimeter is done to measure the pulse rate and blood pressure. The blood pressure obtained by the puslimeter is compared with the practical values measured by electronic or mercury liquid blood pressure meters. The detail analysis of a pulse wave measured by a wrist wearable cuffless pulsimeter detecting the changes of the magnetic field can be used to develop a new diagnostic algorithm of blood pressure applying for oriental medical apparatus.

A Case Study of Sea Bottom Detection Within the Expected Range and Swell Effect Correction for the Noisy High-resolution Air-gun Seismic Data Acquired off Yeosu (잡음이 포함된 여수근해 고해상 에어건 탄성파 탐사자료에 대한 예상 범위에서의 해저면 선정 및 너울영향 보정 사례)

  • Lee, Ho-Young
    • Geophysics and Geophysical Exploration
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    • v.22 no.3
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    • pp.116-131
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    • 2019
  • In order to obtain high-quality high-resolution marine seismic data, the survey needs to be carried out at very low-sea condition. However, the survey is often performed with a slight wave, which degrades the quality of data. In this case, it is possible to improve the quality of seismic data by detecting the exact location of the sea bottom signal and eliminating the influence of waves or swells automatically during data processing. However, if noise is included or the sea bottom signal is weakened due to sea waves, sea bottom detection errors are likely to occur. In this study, we applied a method reducing such errors by estimating the sea bottom location, setting a narrow detection range and detecting the sea bottom location within this range. The expected location of the sea bottom was calculated using previously detected sea bottom locations for each channel of multi-channel data. The expected location calculated in each channel is also compared and verified with expected locations of other channels in a shot gather. As a result of applying this method to the noisy 8-channel high-resolution air-gun seismic data acquired off Yeosu, the errors in selecting the strong noise before sea bottom or the strong subsurface reflected signal after the sea bottom signal are remarkably reduced and it is possible to produce the high-quality seismic section with the correction of ~ 2.5 m swell effect.

Determination of Localized Defects in Wood by the Transfer Time of Ultrasonic Waves (초음파의 통과시간을 이용한 목재 결점부위의 평가)

  • Park, Jun-Chul;Hong, Soon-Il
    • Journal of the Korean Wood Science and Technology
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    • v.36 no.1
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    • pp.61-68
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    • 2008
  • The effect of rupture on the speed of ultrasonic wave was investigated with the PUNDIT and the effective detecting method of defects, moving transmitter and receiver. The speed of ultrasonic wave according to the course of rupture was not affected by transmitter and receiver and in the course of parallel rupture, but only in the course of vertical rupture. When rupture was not located on the ultrasonic wave progressing course, rupture was not detected. However, if rupture was formed perpendicularly to the ultrasonic wave progressing course but located on the ultrasonic wave progressing direction, rupture can be detected. Also, the rupture can be detected, when one transmitter and receiver was placed at top and the other at bottom. After detecting rupture in a part, rupture was determined accurately, placing and moving two transmitters and receivers at width.

Application of the Alkaline Comet Assay for Detecting Oxidative DNA Damage in Human Biomonitoring (인체 산화적 DNA손상에 대한 Human Biomonitoring도구로서 Alkaline Comet Assay의 활용 가능성 연구)

  • 박은주;강명희
    • Journal of Nutrition and Health
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    • v.35 no.2
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    • pp.213-222
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    • 2002
  • The alkaline comet assay has been used with increasing popularity to investigate the level of DNA damage in biomonitoring studies within the last decade in Western countries. The purpose of this study was to evaluate the usefulness of the alkaline comet assay as a biomarker of oxidative DNA damage for monitoring in the Korean population, and also to evaluate the effect of nutritional status and lifestyle factors on H2O2 induced oxidative DNA damage measured by the alkaline comet assay in human lymphocytes. The study population consisted of 61 healthy Korean male volunteers, aged 20-28. Epidemiological background data including dietary habits, smoking habits and anthropometrical measurements were collected through personal interviews. After blood collection, the comet assay in peripheral lymphocytes and plasma lipids analysis was carried out and the results analyzed. Tail moment (TM) and tail length (TL) of the comet assay were use\ulcorner to measure DNA damage in the lymphocytes of the subjects. Statistically significant (p < 0.05) positive correlations were observed between DNA damage (TM or TL) and smoking habits expressed as cigarettes smoked per day and pack years (r = 0.311 and 0.382 for TM, r = 0.294 and 0.350 for TL, respectively). There were also significant positive correlations between DNA damage parameter and waist-hip ratio. Higher plasma triglyceride levels were associated with increased damage to DNA. There were no correlations between the consumption frequencies of vegetables and DNA damage to the subjects. However, consumption frequencies of fruit and fruit juice intake were inversely associated with the TM and TL. The results indicate that die comet assay is a simple, rapid and sensitive method for detecting lymphocyte DNA damage induced by cigarette smoking. Consumption of fruit or fruit juices could potentiall modify the damaged DNA in the human peripheral lymphocytes of young Korean men.

Lung Cancer Screening with Low-dose Computed Tomography (저선량 CT를 이용한 폐암의 선별 검사)

  • Hwang, Jung Hwa
    • Tuberculosis and Respiratory Diseases
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    • v.57 no.2
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    • pp.118-124
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    • 2004
  • Lung cancer is the leading cause of cancer death for men and women in the industrialized world. It is desirable to detect disease at a stage when it is not causing symptoms and when control or cure is possible. If the screening test detects patients with the disease at an early stage, they can be examined to confirm the diagnosis and intervention can alter the natural history of the disease. The results of screening programs designed to detect early lung cancer using either conventional chest radiograph or sputum cytology are disappointing for a diagnostic screening test. Because of advances in helical CT imaging techniques, screening for lung cancer has been suggested as a possible method of improving outcome. Findings in recent publications suggest that substantial dose reduction is possible in chest CT. The advantages of low-dose CT are more sensitive than chest radiograph for detecting small pulmonary nodules that may be lung cancers, shorter scanning time than conventional chest CT scan without intravenous contrast injection, cheaper cost than standard CT, low radiation dose. However, the true clinical significance of the small tumors found by screening is still unknown, and their effect on mortality awaits future investigation. Furthermore, in addition to detecting an increased number of lung cancers, low-dose CT found at least one indeterminate nodule in many of all screened patients. The majority should be benign but evaluation of all these indeterminate nodules is not a trivial problem in routine practice. In conclusion, lung cancer screening with low-dose CT is a complex subject. The true effectiveness of lung cancer screening (a reduction in mortality from lung cancer) with low-dose CT can be determined through well-designed randomized control trials with enrolment of appropriate subjects.

Optimization of Design Variables of Detection Algorithm for Loss of Balance Using a Linear Internal Model (균형상실의 검출 성능 향상을 위한 내부 모델의 설계변수 선정 및 민감도 평가)

  • Kim, Kwang-Hoon;Kim, In-Su;Son, Kwon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.34 no.9
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    • pp.1153-1160
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    • 2010
  • The detection algorithm for loss of balance had three main parts: one for processing data, another for constructing an internal model, and a third for detecting the loss of balance. The part related to the internal model is the most important part of the algorithm. The purpose of this study is to evaluate the effect of variables associated with the internal model on the success rate of the algorithm. The internal model depends on the type of linearization adopted and the operating period of the algorithm. The design variables were evaluated by performing sensitivity analysis of the variables of the internal model in order to obtain the success rate of the algorithm. The results showed that the most sensitive variable was the period and the period of 0.3 s yielded the highest success rate of 97.1%. Further, the ranges of the design variables that can facilitate a success rate of over 95% are presented.