• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3037-3040
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• 2013

Introduction: Mammography is the most basic modality in breast cancer imaging. However, the overlap of breast tissue depicted on conventional two-dimensional mammography (2DMMG) may create significant obstacles to detecting abnormalities, especially in dense or heterogeneously dense breasts. In three-dimensional digital breast tomosynthesis (3DBT), tomographic images of the breast are reconstructed from multiple projections acquired at different angles. It has reported that this technology allows the generation of 3D data, therefore overcoming the limitations of conventional 2DMMG for Western women. We assessed the detectability of lesions by conventional 2DMMG and 3DBT in diagnosis of breast cancer for Japanese women. Methods: The subjects were 195 breasts of 99 patients (median age of 48 years, range 34~82 years) that had been pathologically diagnosed with breast cancer from December 20, 2010 through March 31, 2011. Both conventional 2DMMG and 3DBT imaging were performed for all patients. Detectability of lesions was assessed based on differences in category class. Results: Of the affected breasts, 77 (75.5%) had lesions assigned to the same categories by 2DMMG and 3DBT. For 24 (23.5%) lesions, the category increased in 3DBT indicating improvement in diagnostic performance compared to 2DMMG. 3DBT improved diagnostic sensitivity for patients with mass, focal asymmetric density (FAD), and architectural distortion. However, 3DBT was not statistically superior in diagnosis of the presence or absence of calcification. Conclusions: In this study, 3DBT was superior in diagnosing lesions in form of mass, FAD, and/or architectural distortion. 3DBT is a novel technique that may provide a breakthrough in solving the difficulties of diagnosis caused by parenchyma overlap for Japanese women.

• 대한기계학회논문집A
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• 제37권10호
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• pp.1201-1206
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• 2013

풍력 발전 블레이드의 제조 및 운영 중에 발생하는 결함들은 블레이드의 수명과 안전성에 큰 영향을 미친다. 일반적으로 블레이드의 제조 과정에서는 박리, 기공, 주름, 모재 균열 등과 같은 결함이 발생한다. 본 연구에서는 이미지 상관 기법을 이용하여 변형률 분포를 확인함으로써 블레이드의 제조 과정에서 주로 나타나는 결함 중 하나인 기공 결함의 검출능을 조사하였다. $0^{\circ}/{\pm}45^{\circ}$의 섬유 방향을 가진 4 Ply 로 적층된 GFRP 복합재 시험편에 인공적인 기공 결함을 삽입하여 기공의 크기 및 위치에 따른 검출 의존성을 조사하였다. 기공의 크기는 지름 1, 2, 3 mm 이며, 기공의 위치는 시험편 표면으로부터 0.5, 1.0, 1.5 mm 깊이에 삽입하였다. 부하된 시험 하중은 최대 200 MPa 이며, 이미지 상관 기법을 통해 변형률 분포를 획득하여 지름 2, 3 mm의 기공과 깊이 0.5, 1.0 mm의 기공 결함을 검출할 수 있었다.

• 한국환경농학회지
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• 제1권1호
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• pp.14-21
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• 1982

N-Methylcarbamate계(系) 농약(農藥)의 잔류분석법(殘留分析法)을 확립(確立)하기 위하여 MIPC, XMC, BPMC, propoxur, carbofuran 및 carbary에 대하여 diazo화(化)에 의한 비색정량(比色定量)과 N-trifiuoroacetyl (TFA)화(化), pentafluorobenzyl ether(PFB)화(化) 및 dinitrophenyl ether (DNP)화(化)에 의한 유도체(誘導體)의 gas chromatography (ECD)法을 비교검토(比較檢討)하였다. 1) N-Methylcarbamate의 diazo화(化)에 의한 최대흡수파장(最大吸收波長)은 MIPC, XMC, BPMC, propoxur, carbofuran이 460 ㎚이었고 carbaryl은 510 ㎚이었다. 2) 비색법(比色法)에 의한 carbamate의 현미(玄米)와 사과중(中) 회수솔(回收率)은 명명(各各) $80{\sim}104%$, $98{\sim}120%$이었고, 50 g의 시료분석시(試料分析時) 최대검출한계(最大檢出限界)는 $0.03{\sim}0.05$ ppm의 범위(範圍)이었다. 3) Gas chromatography에 의한 carbamate의 분석(分析)에서는 DNP$0.01{\sim}0.2$ppm첨가시(添加時) 현미(玄米)에서 $74{\sim}94%$, 수도체(水稻體)에서 $78{\sim}93%$, 사과에서 $82{\sim}99%$의 범위(範圍)이었고 검출한계(檢出限界)는 50g의 시료분석시(試料分析時) TFA 0.01 ppm PFB 0.005ppm, DNP 0.01ppm이었다.

• 대한의용생체공학회:의공학회지
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• 제19권2호
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• pp.119-128
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• 1998

SPECT 장치는 감마 카메라로 촬영된 일련의 투사영상을 재조합, 재구성하여 횡단면 단층상을 생성하는데, 이때 투사 영상을 획득하는 과정에서 여러 물리적 요소들이 개입되어 투사 영상의 왜곡을 가져온다. 이들 변질 요인들 가운데서도 광자수 제한에 따른 노이즈 변질이 가장 심각한 요인이기 때문에, 투사 영상에 대한 필터링은 노이즈 평활화(smoothing)가 가장 기본적인 방법이다. 그러나 단순한 저역통과 필터링(low-pass filtering)이 투사영상의 윤곽선이나 기타영상구조들을 번지게 함으로써 재구성 영상의 질을 떨어 뜨린다는 사실은 이미 알려져 있다. 주요 영상 구조들을 효과적으로 유지하면서도 노이즈를 억제시키기 위한 한 접근으로 적응적 필터링 기법이 많은 연구자들의 관심을 모으고 있다. 본 논문에서는, 재구성 영상에서의 '최소 검출가능 이상조직의 검출 신뢰도 향상'이라는 관점에서 최적 필터를 설계하였던 이전 연구와 관련하여, 주어진 물리적 조건하에서의 SPECT 이상조직 검출능에 근거된 투사 영상 복원을 위한 적응적 필터링 기법을 제안한다. 결과적으로, 제안된 필터링 알고리즘은 SPECT 영상 재구성시 우수한 이상조직 검출능을 보였으며, 특히 다양한 대조도의 이상조직들을 포함하고 있는 모형 실험에서 보여준 본 필터링 알고리즘의 이상조직 검출능 결과는 실제 SPECT데이터 적응시 좋은 결과를 기대할 수 있게 하였다.

• 한국산학기술학회논문지
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• 제22권2호
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• pp.76-84
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• 2021

품질보증활동은 양산단계에서 위험 식별을 기반으로 품질에 영향을 주는 인자를 확인할 수 있다. 위험 식별은 고장 분석을 통해 이루어지며, 회전익 항공기 착륙장치에 대한 고장 분석 방법은 고장 유형 영향 분석(FMEA)으로 선정하였다. FMEA는 고장 유형에 대해서 심각도, 발생도, 검출도에 대한 정보를 결합하여 품질에 영향을 미치는 인자를 확인하는 방법이다. FMEA 결과는 위험도를 통해 고장 우선순위를 결정한다. 하지만 심각도, 발생도, 검출도에 대한 중요도는 동일하게 구성된다. Dempster-Shafer 증거 이론은 경험과 주관이 반영된 의견에 대해서 불확실성 분석을 수행한다. 또한, Dempster-Shafer 증거 이론은 믿음 함수와 개연성 함수를 구성할 수 있으며, 믿음 함수와 개연성 함수를 통해 가설의 믿음 정도, 신뢰도를 확인할 수 있다. 회전익 항공기 착륙장치는 이륙 및 착륙 시 충격을 받는 구성품으로, 양산단계에서 고장 유형을 관리하는 것이 중요하다. 본 논문에서는 회전익 항공기 착륙장치의 고장 유형에 대한 위험도 분석을 위해 Dempster-Shafer 증거 이론을 이용한 FMEA를 제안하고, 고장 우선순위를 결정한다. 결과는 믿음 함수 및 개연성 함수 곡선을 통해 도출한다.

• Nuclear Engineering and Technology
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• 제39권2호
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• pp.133-142
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• 2007

The Electric Power Research Institute (EPRI) demonstrated a method for monitoring the performance of instrument channels in Topical Report (TR) 104965, 'On-Line Monitoring of Instrument Channel Performance.' This paper presents the results of several models originally developed by EPRI to monitor three nuclear plant sensor sets: Pressurizer Level, Reactor Protection System (RPS) Loop A, and Reactor Coolant System (RCS) Loop A Steam Generator (SG) Level. The sensor sets investigated include one redundant sensor model and two non-redundant sensor models. Each model employs an Auto-Associative Kernel Regression (AAKR) model architecture to predict correct sensor behavior. Performance of each of the developed models is evaluated using four metrics: accuracy, auto-sensitivity, cross-sensitivity, and newly developed Error Uncertainty Limit Monitoring (EULM) detectability. The uncertainty estimate for each model is also calculated through two methods: analytic formulas and Monte Carlo estimation. The uncertainty estimates are verified by calculating confidence interval coverages to assure that 95% of the measured data fall within the confidence intervals. The model performance evaluation identified the Pressurizer Level model as acceptable for on-line monitoring (OLM) implementation. The other two models, RPS Loop A and RCS Loop A SG Level, highlight two common problems that occur in model development and evaluation, namely faulty data and poor signal selection

• Bulletin of the Korean Chemical Society
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• 제27권9호
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• pp.1315-1322
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• 2006

The following study describes the gas chromatography-mass spectrometry (GC-MS) based screening and confirmation analysis of urinary androgenic steroids. Four commercially available solid-phase extraction (SPE) cartridges, Serdolit PAD-1, Sep-pak $C_{18}$, amino-propyl, and Oasis HLB, and three different extractive organic solvents, diethyl ether, methyl tert-butyl ether (MTBE), and n-pentane, were tested for sample preparation. Overall, Oasis HLB combined with MTBE extraction provided the highest recoveries in 39 of 46 total androgenic steroids examined and it showed a good extraction yield (>82.1%) for polar steroids, such as metabolites of fluoxymesterone, oxandrolone, and stanozolol, which gave a poor recovery in both n-pentane (9.2-64.3%) and diethyl ether (22.2-73.6%) extractions. All SPE sorbents tested showed potential, because they were efficient in extraction for most or selective steroids. When applied to positive urine samples based on the results obtained, the present method allowed selective and sensitive analysis for detection of urinary androgenic steroids. The experiments showed that the high-resolution MS method is clearly more efficient than the low-resolution MS technique for the detection of many urinary steroids. However, comprehensive sample clean-up procedures also might be needed especially in confirmation analysis to increase detectability.

• 한국수소및신에너지학회논문집
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• 제31권1호
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• pp.65-72
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• 2020

In this study, the purpose is to identify the risks of the facilities of packaged hydrogen stations. As a risk identification method, failure mode & effect analysis (FMEA), a qualitative risk assessment, was used to analyze failure mode and effects of component of each facility. The analysis criteria were used to derive the risk priority number (RPN) using the 5-point method according to severity, incidence, and detectability. The study analyzed a total of 141 components of 23 types that can be identified on the design of the packaged hydrogen filling station. As a result, 683 types of failures and their causes and effects were identified. and the RPN was number of a total of 1,485. Of these, 10 failure types with a RPN value of 40 or more were deemed necessary. In addition, a list of failure types with a severity score of 5 was identified and analyzed.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.105.1-105.1
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• 2016

Many of the complex materials developed today derive their unique properties from the presence of multiple phases or from local variations in elemental concentration. Simply performing analysis of the bulk materials is not sufficient to achieve a true understanding of their physical and chemical natures. Secondary ion mass spectrometer (SIMS) has met with a great deal of success in material characterization. The basis of SIMS is the use of a focused ion beam to erode sample atoms from the selected region. The atoms undergo a charge exchange with their local environment, resulting in their conversion to positive and negative secondary ions. The mass spectrometric analysis of these secondary ions is a robust method capable of identifying elemental distribution from hydrogen to uranium with detectability of the parts per million (ppm) or parts per billion (ppb) in atomic range. Nano secondary ion mass spectrometer (Nano SIMS, Cameca Nano-SIMS 50) equipped with the reactive ion such as a cesium gun and duoplasmatron gun has a spatial resolution of 50 nm which is much smaller than other SIMS. Therefore, Nano SIMS is a very valuable tool to map the spatial distribution of elements on the surface of various materials In this talk, the surface imaging applications of Nano SIMS in KBSI will be presented.

• ETRI Journal
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• 제37권1호
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• pp.32-42
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• 2015

Orthogonal frequency-division multiplexing (OFDM) suffers from spectral nulls of frequency-selective fading channels. Linear precoded (LP-) OFDM is an effective method that guarantees symbol detectability by spreading the frequency-domain symbols over the whole spectrum. This paper proposes a computationally efficient and low-cost implementation for discrete Hartley transform (DHT) precoded OFDM systems. Compared to conventional DHT-OFDM systems, at the transmitter, both the DHT and the inverse discrete Fourier transform are replaced by a one-level butterfly structure that involves only one addition per symbol to generate the time-domain DHT-OFDM signal. At the receiver, only the DHT is required to recover the distorted signal with a single-tap equalizer in contrast to both the DHT and the DFT in the conventional DHT-OFDM. Theoretical analysis of DHT-OFDM with linear equalizers is presented and confirmed by numerical simulation. It is shown that the proposed DHT-OFDM system achieves similar performance when compared to other LP-OFDMs but exhibits a lower implementation complexity and peak-to-average power ratio.