• Bulletin of the Korean Chemical Society
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• v.24 no.1
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• pp.55-59
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• 2003

This work is focused on analyzing ion-pair interactions and showing the effect of solvent induced inter-atomic attractions in various dielectric environments. To estimate the stability of ion-pairs, SCI-PCM ab initio MO calculations were carried out. We show that the solvent-induced attraction or ‘cavitation' energy of the ion-pair interactions in solution that arises mainly from the stabilization of the water molecules by the generation of an electrostatic field. In fact, even the strong electrostatic interaction characteristic of ion-pair interactions in the gas phase cannot overcome the destabilization or reorganization of the water molecules around solute cavities that arise from cancellation of the electrostatic field. The solvent environment, possibly supplemented by some specific solvent molecules, may help place the solute molecule in a cavity whose surroundings are characterized by an infinite polarizable dielectric medium. This behavior suggests that hydrophobic residues at a protein surface could easily contact the side chains of other nearby residues through the solvent environment, instead of by direct intra-molecular interactions.

• Journal of Technologic Dentistry
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• v.33 no.1
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• pp.15-23
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• 2011

Purpose: Thy yttria tetragonal zirconia polycrystalline(Y-TZP) is a good structural ceramic for dental restoration. But it have a problem that delamination of veneering ceramic from the Y-TZP core materials. The problem generally occur at the interface, thus this study was conducted to evaluate the interface of Y-TZP using scanning electron microscopy(SEM). Methods: To investigate this aspect, high-resolution SEM observations were made of polished and etched (HF content gel) cross-sections of the interface area. Dry and moist veneering porcelain powders were built up on the zirconia base. Results: The extent of this surface faceting is dependent upon the moisture content of the porcelain powder and the firing temperature. More moisture and higher final heating temperature accelerates the observed faceting of the Y-TZP grains at the interface to the veneering ceramic. Conclusion: These changes of the Y-TZP grains indicate that destabilization of the tetragonal phase of zirconia occurs at the interface during veneering with ceramic. It may result in a reduction of the stability of the zirconia and interface.

• Bulletin of the Korean Chemical Society
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• v.24 no.7
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• pp.931-936
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• 2003

By the use of multi-loop thermodynamic boxes developed here by us, we show that models of enzyme catalysis (e.g., split-site model) developed in an attempt to emphasize the importance of the reactant-state destabilization and, thus, demonstrate misleading nature of the fundamentalist position which defines Pauling's transition-state stabilization as the entire and sole source of enzyme catalytic power, should be reduced to the fundamentalist formulation which completely neglects dynamical aspects of mechanism between the reactant and the transition states and dwells only on events restricted to the reactant and transition states alone, because the splitsite (and other canonical) formulations as well as fundamentalist formulations are based, in common, on equilibrium assumptions stipulated by the thermodynamic box logics. We propose to define the equilibrium assumptions as the requisite and sufficient conditions for the fundamentalist position to enjoy its primacy as central dogma, but not as sufficient conditions for its validity, because it is subjected to contradictions presented by existing data.

• Macromolecular Research
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• v.11 no.5
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• pp.303-310
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• 2003

The phase behavior of binary blends of dimethylpolycarbonate-tetramethyl polycarbonate (DMPCTMPC) copolycarbonates and styrene-acrylonitrile (SAN) copolymers has been examined and then compared with that of DMPC/TMPC/SAN ternary blends having the same chemical components and compositions except that the DMPC and TMPC were present in the form of homopolymers. Both binary and ternary blends were miscible at certain blends compositions, and the miscible blends showed the LCST-type phase behavior or did not phase separated until thermal degradation temperature. The miscible region of binary blends is wider than that of the corresponding ternary blends. Furthermore, the phase-separation temperatures of miscible binary blends are higher than those of miscible ternary blends at the same chemical compositions. To explain the destabilization of polymer mixture with the increase of the number of component, interaction energies of binary pairs involved in these blends were calculated from the phase separation temperatures using lattice-fluid theory and then the phase stability conditions for the polymer mixture was analyzed with volume fluctuation thermodynamics.

• Molecules and Cells
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• v.21 no.2
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• pp.218-223
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• 2006

The effect of poly(ADP-ribosyl)ation on the stability of p53 in SK-HEP1 cells treated with UV light was examined. Intracellular levels of p53 increased in cells treated with a low dose of UV light ($20J/m^2$), whereas they increased but then declined after a higher dose of UV ($100J/m^2$). Intracellular levels of p53 in the UV treated SK-HEP1 cells were dependent on the UV dose. Use of proteasome inhibitors revealed that p53 is degraded by proteasomal proteolysis after high doses of UV light. We present evidence that, at low doses, poly(ADP-ribose)polymerase (PARP) poly(ADP-ribosyl) ates p53 and protects it from proteasomal degradation before caspase-3 is activated, whereas at high doses the cells undergo UV induced apoptosis and PARP is cleaved by caspase-3 before it can protect p53 from degradation. Destabilization of p53 by cleavage of PARP may be important in cell fate decision favoring apoptosis.

• Nuclear Engineering and Technology
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• v.35 no.4
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• pp.274-285
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• 2003

Film boiling heat transfer coefficients for a downward-facing hemispherical surface are measured from the quenching tests in DELTA (Downward-boiling Experimental Loop for Transient Analysis). Two test sections are made of copper to maintain Bi below 0.1. The outer diameters of the hemispheres are 120 mm and 294 mm, respectively. The thickness of both the test sections is 30 mm. The effect of diameter on film boiling heat transfer is quantified utilizing results obtained from the two test sections. The measured heat transfer coefficients for the test section with diameter 120 mm lie within the bounding values from the laminar film boiling analysis, while those for diameter 294 mm are found to be greater than the numerical results on account of the Helmholtz instability. There is little difference observed between the film boiling heat transfer coefficients measured from the two test sections. In addition, the higher thermal conductivity of copper results in the higher minimum heat flux in the tests. For the test section of diameter 120 mm, the Leidenfrost point is lower than that for the test section of diameter 294 mm. Destabilization of film boiling propagates radially inward for the 294 mm test section versus radially outward for the 120 mm Test Section.

• International Journal of Naval Architecture and Ocean Engineering
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• v.10 no.2
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• pp.212-224
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• 2018

The characteristics of the relationship between the evolution of propeller trailing vortex wake and skew angle are numerically examined based on four different five-blade David Taylor Model Basin (DTMB) model propellers with different skew angles. Numerical simulations are based on Reynolds-averaged Naviere-Stokes (RANS) equations combined with SST $k-{\omega}$ turbulence model. Results show that the contraction of propeller trailing vortex wake can be restrained by increasing skew angle and loading conditions, and root vortices fade away when the propeller skew angle increases. With the increase of the propeller's skew angle, the deformation of the hub vortex and destabilization of the tip vortices are weakening gradually because the blade-to-blade interaction becomes weaker. The transition trailing vortex wake from stability to instability is restrained when the skew increases. Furthermore, analyses of tip vortice trajectories show that the increasing skew can reduce the difference in trailing vortex wake contraction under different loading conditions.

• Polymer(Korea)
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• v.34 no.4
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• pp.386-389
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• 2010

Thermal behaviors of water in the poly(acrylic acid) (PAA)/water mixtures with 0.1 M NaCl, HCl, and NaOH were investigated by DSC. It showed that adding ions in the mixtures affected the crystallization of water evidently. Compared with the PAA/water mixtures, the $T_m$ of freezable bound water in the mixtures with ions moved to lower values and varied with different cations and anions, due to the stabilization or destabilization of the hydrogen-bonding hydration between polymers and water molecules through ionic hydration. The content of non-freezable bound water in the non-crystalline phase of the PAA/water mixtures with ions was not constant, it increased with total water content gradually, owing to the more binding sites created by ions. The ions could change the distribution of different states of water in the polymer aqueous solutions evidently.

• International Journal of Computer Science & Network Security
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• v.21 no.3
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• pp.141-144
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• 2021

Modern concepts of management of construction production systems require solving the problems of harmonization of the distribution of structural elements on the way to overcoming global destabilization processes. An effective ratio of functional subsystems of production in an environment of mutual influence create sustainable opportunities for production management and contribute to the logical development of the system as a whole in achieving the main goal of harmonious management. The purpose of the study is to develop the concept of effective management of production systems in construction with the harmonious formation of organizational structures. The results of the study allowed to reveal the harmonization approach in improving the interaction of structural elements of production and accelerating their functional sensitivity to changes in the environment. Harmonious production system more effectively adapts to the diversity of interests, goals and actions at all levels of management of different subsystems in any environment.

• Nuclear Engineering and Technology
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• v.56 no.2
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• pp.655-665
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• 2024

The objective of the present experimental study is to investigate the effect of inlet throttling on the thermohydraulic stability of a large scale water-based Reactor Cavity Cooling System (RCCS). The test was performed using the water-based Natural convection Shutdown heat removal Test Facility (NSTF) at Argonne, which represented a ½ axial scale and 12.5° sector slice of the full scale Framatome 625 MW_t SC-HTGR RCCS concept. A two-phase steady state was first established through direct condensate refill, followed by increased inlet throttling over 10 stages, corresponding to a loss coefficient K over the range of 0.05-653. With the inlet throttling gradually increased, the system experienced a unique transition process between stabilization and destabilization. Through a stability analysis, three instability mechanisms were identified in the present test, including a compound mechanism due to both natural circulation oscillations (NCOs) and density wave oscillations (DWOs), Type-II DWOs, and geysering.