• Journal of the Computational Structural Engineering Institute of Korea
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• v.13 no.3
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• pp.285-294
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• 2000

In this paper, a practical procedure for the design optimization of tubular-steel-pile-type substructure in a mooring dolphin is investigated and numerically evaluated. In the finite-dimensional optimum design formulation, geometry and cross-sectional shapes of classified group of piles are identified as design variables. The design objective is the total weight of piles, and the design constraints on stresses, penetration depth, and size limits are imposed. Several classes of practical design alternatives are sought through the linking and fixing of design variables. Among the available numerical optimization codes, both PLBA program and DNCONF subroutine in IMSL library are used. They are based on SQP algorithm and relatively easy to get. A dolphin of numerical example has 20 tubular steel piles, 4 vertical and 16 inclined. Optimum designs for different cases are successfully obtained for the practical purpose.

• Molecules and Cells
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• v.27 no.2
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• pp.225-235
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• 2009

Antibody phage display provides a powerful and efficient tool for the discovery and development of monoclonal antibodies for therapeutic and other applications. Antibody clones from synthetic libraries with optimized design features have several distinct advantages that include high stability, high levels of expression, and ease of downstream optimization and engineering. In this study, a fully synthetic human scFv library with six diversified CDRs was constructed by polymerase chain reaction assembly of overlapping oligonucleotides. In order to maximize the functional diversity of the library, a ${\beta}$-lactamase selection strategy was employed in which the assembled scFv gene repertoire was fused to the 5'-end of the ${\beta}$-lactamase gene, and in-frame scFv clones were enriched by carbenicillin selection. A final library with an estimated total diversity of $7.6{\times}10^9$, greater than 70% functional diversity, and diversification of all six CDRs was obtained after insertion of fully randomized CDR-H3 sequences into this proofread repertoire. The performance of the library was validated using a number of target antigens, against which multiple unique scFv sequences with dissociation constants in the nanomolar range were isolated.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.1234-1239
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• 2003

In the product design process computer-aided engineering and optimization tools are widely utilized in order to reduce the total development time and cost. Since several simulation tools are involved in the process, information losses, omissions, or errors are common and the importance of seamless information exchange among the tools has been increased. In this study ISO STEP standards are adopted to represent the neutral format for CAE/CAO information exchange. The schema of AP209 is used to define the information of finite element analysis and the new schema is proposed to describe the information of structural optimization based on the STEP methodology. The schema is implemented by EXPRESS, information modeling language, and ST-Developer is employed to generate C++ classes and STEP Rose Library by using the schema denoted. To substantiate the proposed approach, the information access interfaces of the finite element modeling software (FEMAP), structural optimization software (GENESIS) and in-house topology optimization program are developed. Examples of the size optimization of a three-bar truss and topology optimization of a MBB beam are shown to validate the information exchange of finite element analysis and structural optimization using STEP standards.

• Korean Journal of Computational Design and Engineering
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• v.19 no.2
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• pp.138-147
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• 2014

In manufacturing companies, different types of production have been developed based on diverse production strategies and differentiated technologies. The production systems have become smart, factories are filled with unmanned manufacturing lines, and sustainable manufacturing technologies are under development. Nowadays, the digital manufacturing technology is being adopted and used in manufacturing industries. When this technology is applied, a lot of efforts, time and cost are required and training professionals in-house is limited. In this paper, we introduce e-FEED system (electronic based Front End Engineering and Design) that is the integrated design and analysis system for optimized manufacturing line development on virtual environment. This system provides the functions that can be designed easily using library and template based on standardized modules and analyzed automatically the logistic and capacity simulation by one-click and verified the result using visual reports. Also, we can review the factory layout using automatically created 3D virtual factory and increase the knowledge reuse by e-FEED system.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.33 no.4
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• pp.217-224
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• 2020

In this study, a framework for optimizing the opening in an outrigger wall is proposed. To solve a constrained bounded optimization problem, an in-house finite element program and SQP algorithm in Python SciPy library are utilized. The openings of the outrigger wall are located according to the strut-tie behavior of the outrigger wall deep beam. A linear interpolation method is used to obtain differentiable continuous functions required for optimization, whereas a database is used for the efficiency of the optimization program. By comparing the result of the two-variable optimization through the moving path of the search algorithm, it is confirmed that the algorithm efficiently determines the optimized result. When the size of each opening is set to individual variables rather than the same width of all openings, the value of the objective function is minimized to obtain better optimization results. It was confirmed that the optimization time can be effectively reduced when using the database in the optimization process.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.47 no.5
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• pp.94-99
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• 2010

This paper presents a design procedure of digitally controlled oscillator(DCO) for power optimization. By controlling coarse tuning bits and fine tuning bits of DCO, the proposed design procedure can optimize the power dissipation and does not affect the LSB resolution, frequency range, linearity, portability. For optimization, the relationship between control bits and power dissipation of the DCO was analyzed. The DCO circuits using and unusing proposed design technique have been designed, simulated and proved using 0.13um, 1.2V CMOS library. The DCO circuit with proposed design technique has operation range between 283MHz and 1.1GHz and has 1.7ps LSB resolution and consumes 2.789mW at frequency of 1GHz.

• Proceedings of the KIEE Conference
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• 1995.07c
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• pp.1120-1122
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• 1995

This paper presents a 2-stage, simple, power-efficient 3V CMOS operational amplifier and its equation based design optimization. Because of its simple structure, it is very suitable as a VLSI library cell in analog/digital mixed-mode systems. The op-amp, which contains a constant-$g_m$ rail-to-rail input stage and a simple feedforward class-AB rail-to-rail output stage, is analyzed and the results are presented in the form of design equations and procedures, which provide an insight into the trade-offs among performance requirements. The results of SPICE simulations are shown to agree very welt with the use of design equations.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.31 no.1
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• pp.1-7
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• 2003

The aerodynamic optimization method for airfoil design was described in this paper. The Navier-Stokes equations were solved to consider the viscous flow information around an airfoil. The Modified Method of Feasible Direction(MMFD) was used for sensitivity analysis and the polynomial interpolation was used for distance calculation of the minimization. The Message Passing Interface(MPI) library of parallel computation was adopted to reduce the computation time of flow solver by decomposing the entire computational domain into 8 sub-domains and one-to-one allocating 8 processors to 8 sub-domains. The parallel computation was also used to compute the sensitivity analysis by allocating each search direction to each processor. The present optimization reduced the drag of airfoil while the lift is maintained at the tolerable design value.

• International Journal of Internet, Broadcasting and Communication
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• v.16 no.2
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• pp.237-246
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• 2024

In recent years, the frequent occurrence of fire accidents in university libraries has posed significant threats to the safety of students' lives and property, alongside negative social impacts. Accurately analyzing the factors affecting evacuation during library fires and proposing optimized measures for safe evacuation is thus crucial. This paper utilizes a specific university library as a case study, simulating fire evacuation scenarios using the Pathfinder software, to assess and validate evacuation strategies and propose relevant optimizations. Pathfinder, developed by Thunderhead Engineering in the United States, is an intuitive and straightforward personnel emergency evacuation assessment system, offering advanced visualization interfaces and 3D animation effects. This study aims to construct evacuation models and perform simulation analysis for the selected university library using Pathfinder. The library's structural layout, people flow characteristics, and the nature of fire and smoke spread are considered in the analysis. Additionally, evacuation scenarios involving different fire outbreak locations and the status of emergency exits are examined. The findings underscore the importance of effective evacuation in fire situations, highlighting how environmental conditions, individual characteristics, and behavioral patterns significantly influence evacuation efficiency. Through these investigations, the study enhances understanding and optimization of evacuation strategies in fire scenarios, thereby improving safety and efficiency. The research not only provides concrete and practical guidelines for building design, management, and emergency response planning in libraries but also offers valuable insights for the design and management of effective evacuation systems in buildings, crucial for ensuring occupant safety and minimizing loss of life in potential hazard situations

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.19 no.12
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• pp.1356-1363
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• 2009

The aim of this research is to construct eigenfrequency optimization codes for plates with Arbitrary Rank Microstructures. From among noise factors, resonance sound is main reason for floor's solid noise. But, Resonance-elusion design codes are not fixed so far. Besides, The prediction of composite material's capability and an resonance elusion by controlling natural frequency of plate depend on designer's experiences. In this paper, First, using computer program with arbitrary rank microstructure, variation on composite material properties is studied, and then natural frequency control is performed by plate topology optimization method. The results of this study are as followed. 1) Programs that calculate material properties along it's microstructure composition and control natural frequency on composite material plate are coded by Homogenization and Topology Optimization method. and it is examined by example problem. 2) Equivalent material properties, calculated by program, are examined for natural frequency. In this paper, Suggested programs are coded using $Matlab^{TM}$, Feapmax and Feap Library with Homogenization and Topology Optimization method. and Adequacy of them is reviewed by performing the maximization or minimization of natural frequency for plates with isotropic or anisotropic materials. Since the programs has been designed for widely use. If the mechanism between composite material and other structural member is identified, extension application may be possible in field of structure maintenance, reinforcement etc. through application of composite material.