Ten barrows, weaned at 28 days (7.2$\pm$0.1 kg BW), were used to evaluate the effects of feeding extruded full-fat soybeans on intestinal morphology and mucosal cell turnover time. All pigs were fed corn-based diets with half of the pigs receiving diets supplemented with 15.5% soybean meal and 3% soybean oil and the remaining pigs fed a diet in which the soybean meal and oil were replaced by 18.5% extruded full-fat soybeans. The pigs were individually placed in $80{\times}150cm$ metabolic cages and fed twice daily an amount approximately equal to their ad libitum intake for a period of 14 days. On day 14, pigs were weighed and then injected intraperitoneally with $^3$H]thymidine ($100{\mu}Ci/kg$ of BW, specific activity 20 Ci/mmol) 6 h after the morning meal. A pig from each treatment was killed 1, 4, 8, 16, or 24 h postinjection and intestinal tissues were collected. Daily gains for pigs fed the soybean diet and extruded full-fat soybean diet were 0.24 and 0.31 kg/day (p=0.05) with feed conversions of 1.58 and 1.39 (p=0.05), respectively. In comparison with pigs fed soybean meal, pigs fed moist extruded full-fat soybeans had a decreased crypt depth in their duodenum and cecum (p<0.1), while the villus height in the mid jejunum and ileum and the total height (villus height plus crypt depth) of the ileum and mid jejunum increased (p<0.05). The villus width in the duodenum and mid jejunum decreased (p<0.05). The number of crypt epithelial cells in the upper jejunum increased but decreased in the ileum, colon and cecum (p<0.05). The number of villus epithelial cells in the ileum and the upper and mid jejunum increased (p<0.05). The time for migration of epithelial cells in the crypt-villus column decreased (p<0.05) in all sites except the upper jejunum, ileum and cecum. The mucosal turnover rate for all intestinal sites except the upper jejunum, colon and cecum decreased (p<0.05). From these data, we conclude that inclusion of moist extruded full-fat soybeans in weanling pig diets can improve the intestinal morphology and slow the migration rate and turnover time of epithelial cells of the small intestine, especially in the mid jejunum compared with soybean meal.
To evaluate the safety status of deteriorated segments in a submarine shield tunnel during its service life, a seepage model was established based on a cross-sea shield tunnel project. This model was used to study the migration patterns of erosive ions within the shield segments. Based on these laws, the degree of deterioration of the segments was determined. Using the derived analytical solution, the internal forces within the segments were calculated. Lastly, by applying the formula for calculating safety factors, the variation trends in the safety factors of segments with different degrees of deterioration were obtained. The findings demonstrate that corrosive seawater presents the evolution characteristics of continuous seepage from the outside to the inside of the tunnel. The nearby seepage field shows locally concentrated characteristics when there is leakage at the joint, which causes the seepage field's depth and scope to significantly increase. The chlorine ion content decreases gradually with the increase of the distance from the outer surface of the tunnel. The penetration of erosion ions in the segment is facilitated by the presence of water pressure. The ion content of the entire ring segment lining structure is related in the following order: vault < haunch < springing. The difference in the segment's rate of increase in chlorine ion content decreases as service time increases. Based on the analytical solution calculation, the segment's safety factor drops more when the joint leaks than when its intact, and the change rate between the two states exhibits a general downward trend. The safety factor shows a similar change rule at different water depths and continuously decreases at the same segment position as the water depth increases. The three phases of "sudden drop-rise-stability" are represented by a "spoon-shaped" change rule on the safety factor's change curve. The issue of the poor applicability of indicators in earlier studies is resolved by the analytical solution, which only requires determining the loss degree of the segment lining's effective bearing thickness to calculate the safety factor of any cross-section of the shield tunnel. The analytical solution's computation results, however, have some safety margins and are cautious. The process of establishing the evaluation model indicates that the secondary lining made of molded concrete can also have its safety status assessed using the analytical solution. It is very important for the safe operation of the tunnel and the safety of people's property and has a wide range of applications.
In this study, the development processes of multiple bars in the channels with erodible banks were investigated by double Fourier analysis. The initially straight channels in the experiment flume were widened with eroding the side banks, and the multiple bars were generated and grew due to stalling of the sediment on the bed. The bars migrated downstream and the size of the bars increased with time. The flow was separated around the bars, and the bed and banks near the bars were scoured due to the impinged secondary flow. The morphologic changes were accelerated by the bank erosion, which affected the fluctuations of sediment discharge downstream. The double Fourier analysis of the bed waves showed that 1-1 mode (alternate bar) was dominant at the initial stage of the channel development. As time increased, 2-3 mode (central or multiple bars) was dominant due to the increased width to depth ratio. Moreover, the number of bars in a cross section of the channel were increased due to the non linearity of alternate bars. The width to depth ratio was increased by the bank erosion, which affected the bar migration and the bar wavelength. However, the dimensionless tractive force was decreased by it.
The adjustment processes and responses of a series of mining pits by sand or gravel mining were investigated by laboratory experiments. The filling processes of the two pits were affected by the bars developed in the upstream of the channel. However, the bars were not developed and the bed was degradated in the downstream of the pits due to little sediment flow, which was trapped in the pits. The submerged angle of repose in the pits was nearly constant when the pits were being filled. After the filling processes of the pits were finished, the pit was speedily filled with sediment, and the bed was aggradated and migrated with speed. However, the angle of repose decreased. As the distance between the upstream pit and the downstream pit increased, the bed of the pit downstream was tailcutted and degradated. The migration speed of the pit decreased. However, the dimensionless pit depth increased as the distance between the pits increased. The dimensionless pit depth increased with time.
Journal of Korean Society of Coastal and Ocean Engineers
/
v.10
no.4
/
pp.165-173
/
1998
Analytical solutions to predict the movement rate of submerged mound are derived using the convection coefficient and the joint distribution function of wave heights and periods. Assuming that the sediment is moved onshore due to the velocity asymmetry of Stokes' second order nonlinear wave theory, the micro-scale bedload transport equation is applied to the sediment conservation. The nonlinear convection-diffusion equation can then be obtained which governs the migration of submerged mound. The movement rate decreases exponentially with increasing the water depth, but the movement rate tends to increase as the spectral width parameter, $ u$ increases. In comparison of the analytical solution with the measured data, it is found that the analytical solution overestimates the movement rate. However, the agreement between the analytical solution and the measured data is encouraging since this over-estimation may be due to the inaccuracy of input data and the limitation of sediment transport model. In particular, the movement rates with respect to the water depth predicted by the analytical solution are in very good agreement with the estimated result using the discritization technique with the hindcast wave data.
Geophysical survey techniques, such as electromagnetic(EM), GPR, and electrical method, have been tested in the landfill area to evaluate the applicability of these methods to soil contamination measurement. The EM method has proven to be excellent on mapping the areal distribution of contaminants and the migration path for leachate. Since the field operation of EM technique is simple as well as fast, we think the EM method must be the first choice for these purposes. Electrical survey techniques have proven to be very effective on mapping sectional distribution of contaminants. Generally, the GPR method is very good on high resolution survey of shallow depth, and field data acquisition is simple, too. But the resistivity method gives better information on deep area, for example, deeper than the depth of 20 m.
Seong-Ho Jin;Eun-Mi Lee;Jun-Beom Park;Youngkyung Ko
Journal of Periodontal and Implant Science
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v.54
no.2
/
pp.85-95
/
2024
Purpose: Developmental endothelial locus-1 (DEL-1) plays a role in regulating neutrophil migration within the periodontium. The objective of this study was to evaluate the levels of DEL-1 in saliva and gingival crevicular fluid (GCF), as well as the number of neutrophils in patients with periodontitis. Methods: Forty systemically healthy, non-smoking periodontitis patients participated in this study. Clinical periodontal parameters, including the plaque index, probing pocket depth (PPD), clinical attachment level, bleeding on probing, modified sulcular bleeding index, and marginal bone level, were measured. Levels of DEL-1, interleukin (IL)-1β, IL-6, and IL-8 in unstimulated saliva samples, as well as DEL-1 in the GCF of 3 teeth from each participant, were assessed. Neutrophil counts in oral rinse and GCF samples were recorded. Spearman correlation coefficients were used to examine the correlation between protein levels, clinical parameters, and neutrophil quantities. Participants were divided into 2 age groups (those under 50 years and those 50 years or older) in order to investigate potential age-related differences. Results: DEL-1 levels in the GCF showed a negative relationship with PPD (sum). Neutrophils in oral rinse samples were positively correlated with PPD, IL-8, and IL-1β levels. Neutrophils in GCF exhibited a positive correlation with PPD (sum). Salivary DEL-1 levels showed correlations with IL-8 and IL-1β, but not with the clinical parameters of periodontitis. Conclusions: The negative relationship observed between PPD and GCF DEL-1 levels is consistent with the proposed protective role of DEL-1.
Journal of the Korean Society of Marine Environment & Safety
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v.19
no.4
/
pp.327-333
/
2013
In order to see the stratification phenomenon in the coastal area induced by oceanographic conditions of the open sea, we analyzed the CTD (Conductivity-Temperature-Depth) data taken from the oceanographic survey on February 16~28, 2013. The stratification in Jukbyun coast was stronger than those of Sokcho and Gampo coast. Jukbyun line (104 line in the Serial Oceanographic Observation of National Fisheries Research and Development Institute) showed the anticyclonic eddy in the vertical distribution of temperature. The isotherm of $10^{\circ}C$ was concaved to the depth of 200 m in the middle station (station no. 9) of the line 104. It showed above $4^{\circ}C$ in positive temperature anomaly in the depth of 100~200 m in the middle station (station no. 9) of the line 104. This positive temperature anomaly was stretched to the coastal area with shallower depth. It is suggested that the stratification in Jukbyun coast was resulted from the onshoring of the Ulleung warm eddy. The movement of warm eddy may be act as a block to migration of cold water fishes like cod.
Journal of the Korean Association of Oral and Maxillofacial Surgeons
/
v.35
no.2
/
pp.112-119
/
2009
Extracellular matrix(ECM) is known to function as a reservoir of endogenous growth factors, can be an effective delivery system of growth factor that easily lost bioactivity in solution. Fibrillar collagens like type I collagen, are the major constituent of the ECM and structural protein of bone. Also, it can be a scaffold for osteoblast migration. The purpose of this study was to compare the effects of absorbable Atelo-collagen Sponge($Teruplug^{(R)}$) insertion in tooth extraction sites on periodontal healing of the mandibular second molar after the extraction of the impacted third molar. The study population comprised 31 cases who had been scheduled for surgical removal of impacted mandibular third molars. All patients were in good general health and were not using any medication that would influence wound healing after surgery. In 15 cases control group, none was inserted into the tooth extraction site. In 16 cases experimental groups, $Teruplug^{(R)}$ was inserted into the tooth extraction site. We evaluated tooth mobility, pocket depth, gingival margin level preoperatively and 1 week, 2 weeks, 4 weeks, and 3 months postoperatively. The change was compared with two groups using Mann-Whitney test. The results were as follows. 1. There was no significant change of tooth mobility on both groups. 2. There was tendency of decreasing of previous pocket depth causing tooth extraction on both groups. 3. On gingival margin level, there was various change according to initial swelling and loss of attachment on both groups. 4. There was tendency of decreasing of gingival margin level on both groups because of removal of inflammation and decreasing of previous pocket depth. 5. There was large change of pocket depth on buccal middle, distal, lingual distal area because of tooth extraction and bone reduction. Compared with the control group and experimental group, we observed significant difference during some periods. The results of this study suggest that absorbable atelo-collagen sponge($Teruplug^{(R)}$) is relatively favorable bone void filler with prevention of tissue collapse, food packing and enhance periodontal healing.
Journal of the Korean Society of Fisheries and Ocean Technology
/
v.35
no.4
/
pp.404-409
/
1999
The in situ target strengths of, maurolicus muelleri were measured by the split beam echo sounder system at the frequency of 38kHz.Target strengths were measured during the night time in order to obtain the pure separated echoes from the scattered individual. And also it was to establish reasonable threshold due to taking the signals like as the planktons and etc.Since Maurolicus muelleri is a typical micronektonic fish, they mainly consisted of deep scattering layers(DSLs), and had a vertical migration perrodically during daytime and at night.We found that the Maurolicus muelleri occupied about 99% of total catch. Total length ranged from 4.5 to 5.7cm with a mean of 5.2cm and a standard deviation of 0.22cm.The target strengths of Maurolicus muelleir ranged from -60.4 to - 52.7dB and -59.2 to - 52.5 dB in the water layer of 10~30m and 30~50m depth, perspectively. Mean target strength was -57.1dB/fish and -28.5dB/kg. The target strength had the relation with the total length of the fish as, TS=20logL-71.4.
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