• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.8
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• pp.3933-3940
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• 2013

The purpose of present study was to determine the frequency of RA with age and to investigate the age-related trends and changing-factors in RA, CA and IAs. The refractive power of the eye and the power of corneal anterior surface were measured with auto-refractor among 1,017 inhabitants aged 5 to 59 years in Cheongju in July 2010. The overall frequency of RA was 22.7%, and frequency of RA increased from 8.9% in 5~9 years age group to 36.8% in 20~29 years age group. It then dipped to 19.2% in 40~49 years age group but increased again 28.6% in 50~59 years age group. $J_{45}$ components for RA, CA, and IAs were fairly stable in different age groups, the changes in $J_0$ components for both RA and CA appeared to be decreased after age of 30 years. In addition, the refractive power on the vertical direction was changed slightly with age, but the refractive power on the horizontal direction was changed significantly with age. It was expected that the change in the frequency of astigmatism with age was due to the change in the refractive power of horizontal meridian.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.2
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• pp.153-162
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• 2014

Purpose: This study was assessed to investigate the change of subjective and/or objective symptoms and the light transmittance of lens caused by the use longer than recommended wearing time of daily disposable circle contact lenses (circle lens) in dry eyes. Methods: Three daily disposable circle lenses made of etafilcon A, hilafilcon B, and nelfilcon A were applied on 30 dry eyes with smaller tear volume than normal eyes in their twenties free from any eye diseases by when subjects complained any kind of discomfort. On the first and the last days of lens wearing, subjective discomfort, blinking rate, lens centration on corneal surface and visible light transmittance of lens were recorded at every case and compared. Results: The circle lens wearers complained subjective discomfort and quit the lens wearing when they wore the circle lens longer than 10 hours even though there were some difference according to the lens materials of daily disposable circle lens. However, around 20% of dry eyes could wear the circle lens made of non-ionic materials longer than 40 hours. Dry eyes showed most sensitive feeling of subjective discomfort against the circle lens made of etafilcon A among three different lens materials. On the last day of lens wearing, the representative subjective discomforts were irritation, stiffness, dryness and tiredness. When the subjects wore circle lens more than the recommended time, blinking rate was significantly increased about 20~30% regardless of lens materials when it compared with the values right after lens wearing. On the last day of lens wearing, the vertical direction of lens centration was shifted to pupil center however, its distribution in horizontal direction was wide compared with the distribution right after lens wearing. Especially, the centration of etafilcon A lens was unstable. Furthermore, the visible light transmittance of 3 different circle lenses in dry eyes has significantly been reduced around 15% averaged. Conclusions: From these results, it was known that the increase of dryness and stiffness caused by overusage of daily disposable circle lens induced excess irritation and decreased visible light transmittance and caused significant more blinking, which provoked lens decentration. It was also revealed that dry eyes showed sensitive reaction subjectively and objectively against the overusage of circle lens made of high water content/ionic lens material even there were some difference of the degree depending on the individual and the lens material. Thus, this research can be suggested as the basic reference for the education about some unexpected problems and the side effect caused by the wearing of circle lens in dry eyes.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.3
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• pp.311-319
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• 2012

Purpose: One of the critical aspects on dispensing glasses is to match the center of pupils to the optical center of lenses as the mismatched glasses are able to induce uncomfortable effects called prism which has been known to induce phoria, a main cause for asthenopia in many cases. Therefore, we investigated the induced prism occurred by mismatching centers between the center of pupils and the optical center of lenses. Methods: In this study, total 103 subjects were examined whether the center of pupils and the optical center of lenses are matched in horizontal and vertical directions, and then, the data was categorized into 4 groups based on the structural components of glasses. Total amount of prism was compared to show the effect of the glasses frame on the prism induction, and the value of measured prism was compared with the German RAL-RG 915 regulations. Results: The results in respect to the horizontal component showed that the induced prism was not found in 10.7% of total subjects. 73.8% of total subjects were influenced by induced prism, the range of prism was in a tolerance level. However, the 15.5% of total subjects seemed to be influenced by prism which is out of the criterion of tolerance. In case of vertical component, 23.3% of total subjects showed no effects of prism while early adopting glasses, 54.4% of total subjects showed a little prism effect within the criterion of tolerance, and 22.3% of total subjects showed the prism effect out of the tolerance range. This data indicates that group A and B that are less likely adjustable by fitting induce more prism than group C and D in horizontal and vertical components. Conclusions: In higher refractive error condition, it was found that aligning the optical center of lenses with the center of pupils by pre-fitting of glasses frame minimized prism induction in horizontal and vertical components, which ameliorates ocular fatigue. Therefore, appropriate optometric dispensing through fitting by opticians and precise design about monocular PD and monocular Oh are necessary to improve visual perception.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.3
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• pp.191-201
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• 2016

Purpose: In the present study, the effect of artificial tears with different ingredients on tear film stability and subjective symptoms of dry eyes in the early stage of soft contact lenses wear was investigated. Methods: The three kinds of artificial tears and saline solution were respectively applied onto 50 dry eyes which wore soft contact lenses made of etafilcon A. Then, non-invasive tear film break-up time (NIBUT) was measured at every five minutes for 30 minutes right after the instillation of artificial tears, and the changes in blink rate and subjective symptoms were estimated after 30 minutes from the instillations. Results: All three kinds of artificial tears increased NIBUT larger than saline. The effect of increasing NIBUT immediately after the instillation of artificial tears was the largest when the artificial tear containing viscosity enhancer was used. The duration time of the effect was the longest when the artificial tear having both surfactant and viscosity enhancer was applied. The blink rate was not significantly changed when both artificial tears and saline solution were instilled. Subjective symptoms were significantly improved by the instillation of both artificial tears and saline solution and dryness, irritation, tiredness, stiffness, dazzling were improved by the use of most solutions. However, the subjective symptoms were rebounded to the level before the instillation of artificial tears after 30 minute-instillation. Conclusions: It was revealed that both artificial tears and saline solution could improve the subjective symptoms of dry eye in the early stage of soft contac lenses however, the effect of these solutions on the tear film stability was different according to the components. From the results, it is suggested that the proper selection of artificial tears is necessary for the improvement of dry eye symptoms at the early stage of soft contact lenses wear in dry eye.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.237-246
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• 2015

Purpose: The present study was conducted to reveal the correlation of structural denaturation and decrease of enzyme activity when the antioxidative enzymes, superoxide dismutase (SOD) and catalase (CAT) were repeatedly exposed to UV-B, and further investigate whether the denaturation and inactivation of those enzymes can be effectively blocked by using UV-inhibitory RGP lens. Methods: Each enzyme solution was prepared from the standardized SOD and CAT, and repeatedly exposed to UV-B of 312 nm for 30 minutes, 1 hour and 2 hours a day over 1, 2, 3, 4 and 5 days. Structural denaturation of SOD and CAT induced by repeat UV-B irradiation was confirmed by the electrophoretic analysis, and their enzyme activity was determined by the colorimetric assay using the proper assay kit. At that time, the change in structure and activity of the antioxidant enzymes directly exposed to UV-B was compared to the case that UV-B was blocked by UV-inhibitory RGP lens. Results: SOD exposed repeatedly to UV-B showed the polymerization pattern in the electrophoretic analysis when it repeatedly exposed for 30 min a day, however, the change of its activity was less than 10%. On the other hand, CAT repeatedly exposed to UV-B reduced size and density of the electrophoretic band which indicated a structure denaturation, and its activity was significantly decreased. In the case that the repeat exposure time was longer, CAT activity was completely lost even though some enzyme band occurred in the electrphoretic analysis. In addition, the degeneration of CAT due to UV-B irradiation was inhibited to some extent by using RGP lens with a UV-B blocking of 63.7%, however, it was not completely inhibited. Conclusions: From these results, it was revealed that the structural denaturation of antioxidative enzymes was not perfectly correlated with the reduction in enzyme activity according to the type of enzyme. It is recommended to minimize the exposure time to UV when wearing contact lens, or wear the contact lenses having UV blocking rate of the FDA Class I blocker or the sunglasses having equivalent UV-blocking rate for reducing the damage of antioxidative enzymes induced by UV.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.31-42
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• 2014

Purpose: The present study was conducted to investigate the effect of the physical properties of RGP lens induced by lens polishing on the actual wearer's subjective comfort, the tear film break-up time and the blinking rate as a follow-up study that revealed the relationship between the lens physical properties during lens manufacturing and lens wearer's factors. Methods: RGP lenses made from the three different polishing conditions (25, 50 and 100 seconds) were applied on 28 eyes of 17 subjects, aged 20 to 29 years, without any known disease and surgical history in the eyes. While the subjects were asked to wear the RGP lenses longer than a week, the questionnaire for the comfortability was administered everyday. Subjective and objective tear break-up time and blinking rate of the wearers were further measured. Results: The wearer's subjective comfortability showed some difference in the type of discomfort and satisfaction score according to the polishing status when wearing RGP lenses made from different polishing conditions longer than a week, and a bigger difference in satisfaction score induced by polishing condition was especially shown in experienced RGP lens wearer rather than un-experienced wearer. In the case of RGP lens wearer compared with the ones without the wearing experience, as the wearing time increased subjective and objective tear break-up time were increased and the blinking rate was decreased. However, subjective and objective tear break-up time were tended to decrease with even longer wearing time when wearing the RGP lens made from the polishment for 100 seconds. Conclusions: These results confirmed that the optimization of physical properties of the lens may not give the same effect on the wearer's subjective and objective symptoms and other factors when actual wearing. From the results, it can suggest that the success rate of RGP lens wear may be changed by physiological factors such as the stabilization of wearer's tear film, comfortability and lens wearing experience when wearing RGP lens based on 'The manufacturing standard for soft contact lens/hard contact lens' provided by Korea Food and Drug Administration.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.2
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• pp.119-126
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• 2016

Purpose: To analyze the effect of accommodative control and change values between subjective refraction (SR) and auto-refraction (AR) according to application of fogging after accommodative stimulation depending on ametropia type. Methods: Myopic ametropia 76 eyes and hyperopic ametropia 52 eyes participated for this study. SR and AR values measured by three test conditions (Before accommodative stimulation; Before AS, After accommodative stimulation; After AS, and After application of fogging; After AF) were compared, respectively. Results: In myopic eyes, (-)spherical power by SR and AR in After AS test was significantly increased as compared to Before AS test, (-)spherical power in After AF test was decreased to the level of Before AS test. The differences of spherical power between SR and AR were highly measured by SR in After AS test, and highly measured by AR in After AF test, respectively. In hyperopic eyes, (+)spherical power of SR significantly decreased in After AS test compared to Before AS test, more (+)spherical power was detected in After AF test compared to Before AS test. (+)spherical power of AR have no significant difference between Before AS and After AS test, but more (+)spherical power was detected in After AF test compared to Before AS test. The differences of (+)spherical power between SR and AR were significant in all test conditions. Among 52 eyes which were measured as hyperopic ametropia, 7 eyes were measured as myopia by SR in After AS test. In case of AR, 25 eyes among 52 eyes were mismeasured as myopia of ranges from -0.25 D to -1.25 D in Before AS test, 26 eyes in After AS test, and 19 eyes in After AF test were mismeasured as myopia of ranges from -0.25 D to -1.25 D. Conclusions: Regardless of ametropia type, accommodative control by After AF test was effective on both refraction process. However, in auto-refraction for hyperopic eyes, the misdetermined proportion of refractive error's type was high due to consistent accommodative intervention in all test condition. Therefore, in order to obtain an accurate value of refractive errors, full correction should be determined by subjective refraction process after fogging method.

• Journal of Korean Ophthalmic Optics Society
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• v.15 no.3
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• pp.213-217
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• 2010

Purpose: To emphasize the necessity of post-fitting by follow-up test, the mis-alignment was analyzed after initial wearing of toric soft contact lenses (TSCL). Methods: After trial contact lenses were worn to 87 eyes with myopic astigmatism for 1 week, we observed the alignment of axis mark on trial contact lenses using slit lamp and corrected the rotated axis by method of LARS. After final fitting, rotation ratio, rotation degree and rotation position were analyzed compared to initial prescription divided to amount of cylinderical and spherical powers. Results: Rotation ratio of TSCL's axis was increased as increment of both cylinderical powers and (-)spherical powers. An average of rotation degree was $10^{\circ}{\sim}13^{\circ}$ which was not related to amount of their powers. Rotation position of TSCL's axis was more to temporal than to nasal. Conclusions: Because mis-alignment of axis after TSCL wearing induce the poor sight, adjustment of axial alignment as a result of follow-up must be performed.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.2
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• pp.217-224
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• 2014

Purpose: This study was conducted to compare and analyze the accommodative system (accommodative response and accommodative lag) according to the material and font size of near visual media that we often encounter in daily life. Methods: Forty adult men and women aged 20 to 30 who not had specific ocular diseases and refractive surgery experience were examined to measure and compare the accommodative response according to the material of near visual media (print paper, newspaper, magazine, the I-Phone, LCD monitor) and font size (6, 8, 10, 12) by using both eyes open-view auto-refractometer. Results: The accommodative stimulus was $2.28{\pm}0.11D$ and the accommodative response was $1.66{\pm}0.30D$. The accommodative lag namely the difference between accommodative stimulus and accommodative response was $0.62{\pm}0.28D$. The accommodative response according to material of visual media using LCD monitor was $1.35{\pm}0.26D$ (p=0.00) and using the I-Phone was $1.55{\pm}0.25D$ (p=0.04). Both of them were statistically significant lower. The accommodative lag using LCD monitor was $0.93{\pm}0.24D$ (p=0.00) and using the I-Phone was $0.73{\pm}0.25D$ (p=0.04) and they were statistically significant higher. The accommodative response and accommodative lag according to font size were not statistically significant (p>0.05). Conclusions: During near working, the accommodative system was more affected by material than font size of visual media. Especially, visual media of non-luminous material (print paper, newspaper, magazine) are considered fewer burdens on eyes than luminous material (I-Phone, LCD monitor) in terms of accommodative system.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.1
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• pp.53-59
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• 2016

Purpose: To investigate an individual phoria compensating effect by measuring the lens adaptation after wearing horizontal prism or spherical lenses at near. Methods: 103 subjects (63 males and 40 females) aged $22.43{\pm}2.07years$ participated for this study. Refractive errors of subjects were fully corrected, and subjects were classified into three groups; esophoria, orthophoria and exophoria. The adaptation test of prism and spherical lenses was performed immediately, 15 minutes and 30 minutes after wearing lenses with $OU\;2\;{\Delta}\;BO$ and S+1.00 D for an esophoria group and $OU\;2\;{\Delta}\;BI$ and S-1.00 D for orthophoria and exophoria groups, respectively. Each measured phoria was compared to phoria measured with fully corrected condition, and the phoria changing effects about both lenses was analyzed. Results: The mean of phoria by prism lenses significantly decreased for every group. The mean of phoria by spherical lenses also significantly decreased in orthophoria and exophoria groups. The esophoria group showed a decreasing tendency but has no significance. The decreased phoria value by prism lens was classified into three steps; 90~100%, 0~10% and 50% or more. According to results of individual distribution ratio, it was 5, 64 and 24 subjects at 30 minutes after wearing lenses, respectively. The decreased phoria value by spherical lens was classified into three steps; 90~100%, 0~10% and 50% or more. According to results of individual distribution ratio, it was 37, 53 and 41 subjects at 30 minutes after wearing lenses, respectively. The subjects having no phoria changed by both prism and spherical lenses were 37.9%. Conclusions: When prescribing to compensate the near horizontal phoria using prism or spherical lens, the pretest for lens adaptation should be taken before prescription.