• Korean Journal of Psychosomatic Medicine
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• v.16 no.2
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• pp.95-102
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• 2008

Objectives : Diabetes patients suffer from severe stress in maintaining the diet therapy and exercise therapy as well as the disease itself, and this stress has bad effects on controlling the glucose level and causes high prevalence rate of depressive and anxiety disorders. These symptoms again have deleterious effects on blood glucose control. A lot of researches about the relationship between glycemic control and symptoms of depression and anxiety and about the positive effects of the treatments of depression and anxiety disorder on glycemic control in diabetic patients are being performed. In Korea, the research regarding the relationship between glycemic control and depression and anxiety symptoms are seldom performed. In this study, we tried to find out the correlation between the glycemic control and depressive symptom and anxiety symptom. Methods : The study included 65 patients(male 34, female 31) with Diabetes in outpatient clinic of the Department of Endocrinology in Dankook University Hospital. We used the HbA1c levels to check glycemic control through blood sample analysis and used Beck Depression Inventory(BDI) and Beck Anxiety Inventory(BAI). Results : Among the 65 Diabetes patients, 21(32.30%) had mild depressive symptoms, and 6(9.23%) had moderate or severe depressive symptoms. The relation of HbA1c and BDI was not statistically significant, but was significant between HBA1c and BAI, (R=0.567, P<0.001). In the linear regression analysis, BAI had an effect on HbA1c($\beta=0.533$, T=5.012, P=0.00), but BDI, diabetes complications, diabetic morbid period and BMI had no effect on HbA1C. The relationship between HbA1c and BDI was not statistically significant, but the relationship between HbA1c and BAI was statistically significant(R=0.254, P<0.001). Conclusions : In this study, the rates of diabetic patients with depressive symptoms were higher, but those with anxiety symptoms were not higher than the general population. We could not find out significant relationship between depressive symptom and glycemic control, but found the significant relationship between the anxiety symptom and glycemic control in diabetic patients.

• Korean Journal of Psychosomatic Medicine
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• v.24 no.2
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• pp.191-199
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• 2016

Objectives : Despite the increased popularity of highly caffeinated beverages, there is little research examining psychiatric adverse effects. The purpose of this study was to investigate the relationships among pattern of highly caffeinated beverage intake and depressive symptom, suicidal ideation, suicidal plan, suicidal attempt in Korean adolescents. Methods : The data was obtained from the 2014 Korean Youth's Risk Behavior Web-based Study by Korea Centers for Disease Control & Prevention. All participants conducted web-based questionnaire survey. Chisquare test and multiple logistic regression analysis were performed to determine the association among highly caffeinated beverage intake pattern, depressive symptom, suicidal ideation, suicidal plan and suicidal attempt adjusting for differences in age, gender, academic achievement, socioeconomic status. Results : A total of 71,638 participants were enrolled in this study. Depressive symptom, suicidal ideation, suicidal plan and suicidal attempt were significantly more frequent in the group with presence of highly caffeinated beverage intake within 1 week than in non-drinker group(p<0.01). Highly caffeinated beverage intake was significantly associated with suicidal attempt(OR=1.99 ; 95% CI, 1.77-2.22). In addition, depressive symptom, suicidal ideation, suicidal plan and suicidal attempt were significantly more common in the group with heavy-drinker who exceed recommended daily intake dose of caffeine than in the group with light-drinker(p<0.01). Heavy drinking of caffeinated beverage was significantly associated with suicidal attempt(OR=4.05 ; 95% CI, 3.02-5.43). Conclusions : We found that highly caffeinated beverage intake was related to more frequent depressive symptom, suicidal ideation, plan, attempt in adolescents. Also, caffeine intake which exceed recommended daily intake dose identified the predictor of suicidal attempt. Our result suggested that clinicians need to be aware of the possible psychiatric adverse effects of highly caffeinated beverage in vulnerable population including young adolescents.

• Korean Journal of Biological Psychiatry
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• v.22 no.4
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• pp.216-222
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• 2015

Objectives The principal aim of the present study was to investigate the characteristic depressive symptoms in patients with social anxiety disorder (SAD) and panic disorder in comparison to patients with depressive disorder. Methods This study included 132 patients with SAD, 128 panic disorder and 64 depressive disorder (major depressive disorder, dysthymia etc.) patients without comorbid psychiatric disorders. The Beck Depressive Inventory (BDI) is used to measure depressive symptoms. We divided BDI into three categories originally described by Shafer AB, including negative attitude toward self, performance impairment, and somatic symptoms. We compared the depressive symptoms of SAD, panic disorder and depressive disorder by using ANOVA. Results Negative attitude toward self was noticeable in SAD (SAD $0.54{\pm}0.23$, panic disorder $0.41{\pm}0.17$, depressive disorder $0.46{\pm}0.11$, p < 0.001). Performance impairment and somatic symptoms were remarkable in panic disorder than in SAD and depressive disorder (performance impairment : SAD $0.39{\pm}0.21$, panic disorder $0.44{\pm}0.14$, depressive disorder $0.40{\pm}0.09$, p = 0.009 ; somatic symptoms : SAD $0.07{\pm}0.10$, panic disorder $0.15{\pm}0.12$, depressive disorder $0.14{\pm}0.08$, p < 0.001). Conclusions The results facilitate an approach to optimal treatment for patients with comorbidity of anxiety disorder and depression.

• Journal of Convergence for Information Technology
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• v.8 no.1
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• pp.59-67
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• 2018

This study was conducted to identify convergence factors affecting depressive symptoms of postmenopausal women through the theory unpleasant symptom. This study was secondary data analysis form Sixth Korea National Health and Nutrition Examination Survey 2015. Study sample of 1,298 menopausal women to evaluate the factors that would influence depressive symptoms, physiological factors, situational factors, and psychological factors. The results showed that significant variables influencing the depressive symptom were income quartile(${\beta}=-.14$, p<.001), health status(${\beta}=.24$, p<.001), and stress(${\beta}=-.20$, p<.001). The explanation power of this regression model was 14. 1% and it was statistically significant. As a result, to improve their depressive symptoms, the nursing interventions are required for postmenopausal women who have the income, health status, and stress.

• The Journal of Internal Korean Medicine
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• v.38 no.5
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• pp.650-657
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• 2017

Objective: This study was performed to report the effect of traditional Korean medicine as a treatment for laryngopharyngeal reflux (LPR) combined with depressive and anxiety disorder. Methods: We treated this patient with traditional Korean medicine and measured symptom severity using the reflux symptom index (RSI), Beck depression inventory (BDI), and Beck anxiety inventory (BAI). Results: After 3 weeks of treatment, most symptoms had decreased. The RSI score dropped from 21 to 8, BDI from 27 to 14, and BAI from 29 to 15. Conclusions: Traditional Korean medicine may be effective as a treatment for LPR combined with depressive and anxiety disorder, and a correlation may exist between LPR and psychological factors. However, more rigorous studies are required to identify exactly what treatment is most efficient for relieving LPR combined with depressive and anxiety disorder and whether LPR and psychological factors are clearly correlated.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.1
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• pp.62-71
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• 2016

Food insecurity is associated with poor health outcomes. In particular, previous studies marked the adverse outcomes on mental health. This study examined the association of food insecurity and mental health in Korean adults using the data from the 2013 Korean National Health and Nutrition Examination Survey (KNHANES). The study population was 5,685 adults in Korea. Food insecurity was examined using 18-items. A diagnosis of depression was considered to be depression. Depressive symptoms were defined as more than 2 weeks of depression feelings. Multivariate logistic regression models examined the associations between food insecurity and depression and depressive symptom. The overall prevalence of depression was 3.8% in the participants. Food insecurity was associated significantly with depression and depressive symptom in the unadjusted and age and sex adjusted model. Food insecurity was associated with depression, depressive symptoms in the multivariate logistic regression model (OR:3.49, OR:3.70). Marginal food insecurity was not associated with depression in the multivariate logistic regression model. The results showed that food insecurity is associated with depression and depressive symptoms in adults. Multi-disciplinary interventions are needed including nutrition, health, health policy, and a healthy environment for the food insecurity group to achieve a better health outcome, especially mental health.

• Journal of Korean society of Dental Hygiene
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• v.19 no.6
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• pp.941-950
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• 2019

Objectives: The aim of this study was to evaluate the relationship between depressive symptoms and oral health status in Korean middle-aged women. Methods: We analyzed data from the sixth Korea National Health and Nutrition Examination Survey (KNHANES VI). The final sample consisted of 2,691 adults aged 40-64 years. The Chi-squared test was used to assess the rate of depressive symptoms, oral health status, and relationship between oral health status and depressive symptoms. Moreover, logistic regression analysis was used to examine the association between depressive symptoms and oral health status. Data were analyzed using SPSS 20.0 program. Results: Overall, 15.1% of subjects experienced depressive symptoms. The rate of depressive symptoms in self-aware oral health, toothache, and mastication problem groups were 19.6%, 19.9%, and 25.3%, respectively. Compared to other groups, the likelihood (odds ratio) of having depressive symptoms was 1.47 (95% confidence interval [CI] : 1.16-1.88), 1.58 (95% CI: 1.22-2.04), and 1.73 (95% CI: 1.32-2.28) higher in self-aware bad oral health, toothache, and mastication problem groups, respectively. Conclusions: We found an association between depressive symptoms and oral health status. Thus, oral health status should be evaluated as a potential risk factor for depressive symptoms.

• Korean Journal of Biological Psychiatry
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• v.10 no.1
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• pp.70-79
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• 2003

Object : Currently, the alteration of cytokine system has been known to play an important role in regard to depressive symptom. We focused on the relationship between immunological parameters and clinical improvement in major depressive disorder. Method : Data were collected on 26 patients with major depressive disorder using a 8-week prospective follow-up design. After 8-week treatment period with fluoxetine, patients were classified into a response group and a non-response group according to their psychopathological outcome as evaluated by Hamilton Depression Rating Scale. The differences of the immunological parameters between pre-treatment phase and post-treatment phase were compared among patients. The difference of those was also compared within each phase among them. The relationship between socio-demographic variables, depression, cytokine, mononuclear cells was examined by correlation analysis. Multiple regression analyses were performed to explore the predictors of clinical improvement of major depressive disorder. Result : Pre-treatment levels of IL-$1{\beta}$ in the response group were significantly higher than those in the non-response group. Pre-treatment levels of IL-$1{\beta}$ of all patients and in the response group were positively correlated with pre-treatment monocyte counts. Patients with subsequent remission showed significantly lower IL-6 values at baseline than those with non-response. Post-treatment values of IL-6 did not differ significantly among the patients. The correlation test showed more frequent relations among cytokines and mononuclear cells in the response group than in the non-responder group. Especially, serum level of IL-6 in pre-treatment phase was only significantly correlated with HAMD score after 8-week treatement phase, while other cytokines and mononuclear cells were not. Pretreatment level of IL-6 was of paramount importance in predicting clinical improvement of depressive symptom. Conclusion : The immune system of major depressive disorder patients might dichotomize the patients into subsequent responders and non-responders. Immune system might be of great influence on the clinical improvement of major depressive disorder. The mode of interaction between depression and cellular immune function and the mediators responsible for the cytokine production need to be studied further.

• Anxiety and mood
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• v.11 no.2
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• pp.149-154
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• 2015

Objective : The aim of the study was to investigate the difference in alexithymia between anxiety disorder and depressive disorder. The second was to evaluate the effect of alexithymia on quality of life in patients with anxiety disorder and depressive disorder. Methods : A total of 175 patients with diagnoses of anxiety disorder or depressive disorder were recruited. Demographic, psychosocial, and clinical data were analyzed, as well as results on the 20-item Toronto alexithymia Scale (TAS-20K), the Symptom Checklist-90-Re-vised (SCL-90-R), a quality of life scale, the Beck Depression scale, and Beck Anxiety Inventory. Results : As compared with the patients with anxiety disorder, patients with depressive disorder showed significantly higher total score on the TAS-20K and for factor 1 (difficulties identifying feelings) and factor 2 (difficulties describing feeling) scales of the TAS-20K and showed significantly lower scores of psychosocial well-being on the quality of life scale. Total scores on the TAS-20K correlated significantly with scores for some subscale on the quality of life scale. Conclusion : This study suggest that patients with depressive disorder had more alexithymic symptoms and worse quality of life compared with those with anxiety disorder. Also, alexithymic symptoms are found to be associated with quality of life. Therefore, clinicians should try to focus on relieving symptoms to help patients restore their psychological well-being and improve their quality of life.

• The Journal of the Korea Contents Association
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• v.14 no.2
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• pp.409-420
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• 2014

The purpose of this study is to examine the level of stress and depressive symptom and to assess the utilization of professional consultation. Data extracted from Community Health Survey (CHS), conducted by Korea Centers for Disease Control and Prevention. The subjects were 174,975 (19-65 years). In result, 'Managers', 'Professionals and related workers', 'Clerks', 'Service workers', and 'Sales workers', 'Equipment, machine operating assembling workers', and 'Armed forces' were more in risk of stress. However, theses groups were less in probability of utilization for stress consultation. Based on these findings, mental health screening program for detecting risk group among occupation classification and employment status will be essential. It may be necessary to have sustainable strategies for utilizing mental health service to reduce the level of stress and depressive symptom of workers.