• 기본간호학회지
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• 제8권2호
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• pp.189-198
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• 2001

The purpose of this study was done to identify the relationship between the level of pain and depression in patients with rheumatoid arthritis. The subjects for this study were 222 patients registered in H University Hospital Rheumatoid Arthritis Center, and the period of data collection was from July 20, 2000 to August 30, 2000. The research instruments used in this study were the Graphic Rating Scale of Pain and the CES-D for depression. The cronbach's ${\alpha}$ of the CBS-D scale was .89. Data analysis, was done by the SPSSWIN 10.0 program using descriptive statistics. The results are as follows. 1) The total pain score ranged from 0 to 147 with a mean score for pain in patients with rheumatoid arthritis of 72.64. 2) The total depression score ranged from 20 to 72 with a mean score of 39.86. 3) There was a significant difference in pain according to sex(F=5.26, p<.05) and education level (F = 3.59, p<.05). 4) There was a significant difference in depression scores according to sex (F=7 76, p<.05) and education level (F=3.02, p<.05). 5) The level of pain had a significant correlation with the level of education level(r=-.174, p<.01). The level of depression was significant correlation with the level of pain (r=.237. p<.01).

• 한국산학기술학회논문지
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• 제20권6호
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• pp.63-73
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• 2019

본 연구는 학령후기 아동의 사회불안 정도와 사회불안에 영향을 미치는 요인을 파악하기 위한 것이다. 설문지를 이용한 서술적 조사연구 방법으로 초등학교에 재학 중인 6학년 아동 278명을 연구대상자로 하였으며, 연구도구는 SASCA-K(Korean Social Anxiety Scale for children and adolescents, 사회불안 척도), SES(Self-esteem Scale, 자아존중감 척도), CAPS(Child and Adolescent Perfectionism Scale, 완벽주의 척도), DSRS-C(Depression Self-Rating Scale for Children, 아동우울 척도), IPPA-R(Inventory of Parent and Peer Attachment-Revised version부모 및 또래애착 척도)을 사용하였다. 수집된 자료는 SPSS WIN 23.0을 이용하여 기술통계, t-test, One-way ANOVA, Pearson correlation, stepwise multiple regression을 실시하였다. 연구결과 학령후기 아동의 사회 불안과 완벽주의, 우울은 긍정적인 상관관계가 있는 반면, 자아존중감, 애착안정성은 부정적인 상관관계가 있었다. 단계적 다중회귀 분석에서는 자아존중감, 자기 지향적 완벽주의, 우울, 부 애착 의사소통이 사회불안에 영향을 주는 요인으로 38% 설명하는 것으로 나타났으며, 사회불안에 가장 영향을 미치는 요인은 자아존중감으로 분석되었다. 학교, 가족, 지역사회의 통합적인 개입을 통해 학령후기 아동의 정신문제를 예방하고 중재하기 위해 건강교육, 상담 및 학교기반 보건교육 프로그램 확대가 필요하다.

• 생물정신의학
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• 제12권2호
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• pp.189-195
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• 2005

Objects:Some studies have suggested that brain-derived neurotrophic factor(BDNF), one of the most important neurotrophins, is involved in pathophysiology of depression and suicide. This study was performed to determine whether there is an abnormality in plasma BDNF concentration in suicidal attempters. Methods:The subjects were 71 suicidal attempters who visited emergency rooms in multi-medical centers. All subjects had been interviewed by using Structured Clinical Interview for DSM-IV(SCID), Hamilton Depression Rating Scale(HDRS), Young Mania Rating Scale(YMRS), and Positive And Negative Syndrome Scale(PANSS). The severity of the suicidal behavior was measured by Lethality of Suicide Attempt Rating Scale(LSARS) and Risk-Rescue Rating(RRR) system. Seventy-one age, sex, and diagnosis matched non-suicidal psychiatric patients who were consecutively admitted to a psychiatric ward during the same period recruited as psychiatric controls. They were drug-naive or drug-free at least more than 2 months. In addition, 80 healthy controls were randomly selected as normal controls. Plasma BDNF level was measured by the enzyme linked immunosorbent assay(ELISA) methods. Results:In overall F-test, differences of the plasma BDNF levels among the groups were statistically significant(F=20.226, p<0.001). In the multiple comparisons(Scheffe), while mean levels of plasma BDNF between normal controls and non-suicidal psychiatric patients were similar(p=0.984), the BDNF levels of suicidal attempters were lower than those of other two groups(p<0.001). LSARS and RRR did not reveal any significant correlations with BDNF levels in suicidal attempters. Conclusion:These results suggest that reduction of plasma BDNF level is related to suicidal behavior and BDNF level may be a biological marker of suicidal behavior.

• 우울조울병
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• 제16권3호
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• pp.140-151
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• 2018

Objectives : The purpose of this study was to examine effects of adjunctive aripiprazole versus bupropion, on depressive symptoms of female depression. Methods : Sixty six female patients with major depressive disorders were enrolled from a six-week, randomized prospective open-label multi-center study. Participants were randomized to receive aripiprazole (2.5-10 mg/day) or bupropion (150-300 mg/day). Montgomery Asberg Depression Rating Scale, 17-item Hamilton Depression Rating scale (HAM-D17), Iowa Fatigue Scale, Drug-Induced Extrapyramidal Symptoms Scale, Psychotropic-Related Sexual Dysfunction Questionnaire scores, and Clinical Global Impression-Severity (CGI-S) were obtained at baseline and after one, two, four, and six weeks. Changes on individual items of HAM-D17 were assessed as well as on composite scales (anxiety, insomnia and drive), and on four core subscales that capture core depression symptoms. Results : Overall, both treatments improved depressive symptoms, without causing serious adverse events. There were significant differences in the HAM-D17 total score (p=0.046) and CGI-S (p=0.004), between aripiprazole and bupropion augmentation, favoring aripiprazole over bupropion. Aripiprazole revealed significantly greater effect size in depressed mood (p=0.006), retardation (p=0.005), anxiety psychic (p=0.032), and general somatic symptom (p=0.01). Conclusion : While both treatments were effective, results of this study suggested that aripiprazole may be preferable, in treating general and core symptoms of female depression.

• 성인간호학회지
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• 제29권3호
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• pp.235-245
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• 2017

Purpose: Reported insomnia and decreased sleep quality are common among older adults. The purpose of this study was to identify factors contributing to insomnia and decreased sleep quality among elderly persons living within a community. The data will be verified with Actigraph which is a non-invasive measurement of rest/activity cycles. Methods: 137 participants over 65 years old were recruited from a senior welfare center. Their mean age was $74.07{\pm}5.18years$ old and majority was women (69.3%). The quality and quantity of nighttime sleep were assessed using Varren-synder-Halper Sleep Scale and a sleep log. Depression and fatigue were assessed using Geriatric Depression Scale Short Form and Fatigue Severity Scale, respectively. Pain was assessed using 11-point Numeric rating scale. An actigraph was used to verify the self-reported sleep. Results: Ninety-two participants (67.2%) reported insomnia. Sixty-eight subjects (49.6%) reported good sleep. Of the participants, 56.2% reported depression and 33.6% reported fatigue. In logistic regression, depression was related to insomnia (OR=3.09, p=.003). Sleep quality was related to depression (OR=2.13, p=.045) and fatigue (OR=2.24, p=.044). The data from the Sleep logs correlated with data obtained from the actigraph. Conclusion: Depression significantly influenced insomnia and sleep quality whereas fatigue only influenced sleep quality. Thus, depression and fatigue should be closely monitored among elderly persons with sleep disturbances.

• 대한불안의학회지
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• 제11권1호
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• pp.3-11
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• 2015

Objective : The aim of this study was to find associations between specific symptoms and suicidal behavior by using global severity on depression scales. Methods : Data were obtained from 1,183 patients of CRESCEND study. Factor analysis of the 17-item Hamilton Rating Scale for Depression (HAM-D) and the Beck Depression Inventory-II (BDI-II) was used to compare symptom clusters between the past suicide attempters and the non-suicide attempters, among the patients with depressive disorders. Results : Factor analyses of HAM-D and BDI-II extracted three factors. Suicide attempters had significantly higher scores on core factor of HAM-D, including depressed mood, feeling of guilt, suicide, work, and activities. The higher scores on all factors of BDI-II or scores correlated with a total of 7 suicide attempts and with known risk factors for suicidal behavior. Conclusion : These findings suggest that the suicide attempters complained of more cognitive, affective, somatic symptoms on BDI-II, but the core factor on HAM-D was the only differentiated factor between the two groups. Clinician-rated scales as well as self-reported questionnaires were valid in measuring suicidal attempts, and the clinical profile may help in guiding the studies of biological correlates and the treatments to reduce suicide risk.

• 동의신경정신과학회지
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• 제22권4호
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• pp.41-50
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• 2011

Objectives : The purpose of this study is to know that Beck Depression Inventory(BDI) score to effect on improvement degree of low back pain after oriental medical treatment. Methods : We analyzed charts of 33 inpatients who were treated in Ja-Seng Hospital of Oriental Medicine and Bu-Cheon Ja-seng Hospital of Oriental Medicine. Subject is divided into Group A(BDI<10) and Group B(BDI${\geqq}$10). Numerical Rating Scale(NRS) and Oswestry Disability Index(ODI) were checked on admission, after 1 week, NRS and ODI were rechecked to estimate the efficacy of treatments. Results : 1. In both groups, NRS was significantly decreased(p<0.05). Analyzed result of the interaction between the two groups didn't show significant difference(p=0.197). 2. In Group A, ODI was significantly decresed(p<0.05). In Group B, ODI wasn't significantly decreased(p=0.058). The interaction analysis between the two groups didn't show significant difference(p=0.173). 3. Analyzing patients with chronic back pain longer than 6 months by the presence of depression tendency and NRS, ODI decrease after 1 week of ambulation, while the NRS reduction showed relevancy by the depression tendency (p<0.05), the ODI reduction didn't(p=0.272). Conclusions : 1. Although improvement of pain before and after the treatment and degree of functional recovery in high-level BDI group was less than low-level BDI group, but it was stastically insignificant. 2. High BDI score of patients with chronic low back pain is the factor of disturbing pain improvement.

• 생물정신의학
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• 제24권3호
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• pp.149-154
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• 2017

Objectives This study investigated associations between symptom severity and neurocognitive functions in patients with major depressive disorder using comprehensive neuropsychological tests. Methods Ten patients with low depression (LD) and 22 patients with high depression (HD) participated. Symptom severity was determined by both the Beck Depression Inventory and the Hamilton Depression Rating Scale. Additionally, anxiety was measured by the Korean version of the State-Trait Anxiety Inventory (STAI-KYZ). Ten subtests of the Korean-Wechsler Adult Intelligence scale (K-WAIS), Stroop test, the word/design fluency tests were administered to assess cognition. Results The LD and HD groups did not differ in any of cognitive measures but anxiety level. Namely, the HD group obtained significantly higher scores on the state (U = 29.50, p < 0.01) and trait (U = 28.50, p < 0.001) anxiety scales than the LD group. A significant interaction effect between trait anxiety and depression severity was observed on the picture arrangement subtest of the K-WAIS [F (1, 27) = 5.09, p < 0.05]. Conclusions Cognitive deficits observed in patients with major depressive disorder may be related to other factors rather than current symptom severity. Trait anxiety possibly moderates the effect of current symptom severity on social judgment in these patients.

• 여성건강간호학회지
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• 제8권3호
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• pp.435-445
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• 2002

Purpose : he study was to examine the effects of aromatherapy program on depression and fatigue in middle aged women. Method : The study was a noneqivalent control group pretest-posttest design. After giving informed consent. Subjects were assigned to the aromatherapy program intervention or control groups. The subjects were given Zung's Self-Rating Scale test before the trial to evaluate their depression. Yoshitake's Fatigue Scale were used to measure the fatigue before and after the trial. Subjects in the experimental group received aromatherapy massage 3 times a week for 20 minutes during 2 weeks and inhaled essence oil from AM 10:00 to PM 8:00 every day for 2 weeks. Result : 1) The decrease in the depression score was statistically significant(p<.000). 2) The decrease in the fatigue score was statistically significant (p<.002). Conclusion : Aromatherapy program is an effective way to treat depression and fatigue in middle aged women. In particular, to compare with aromatherapy massage, inhaling essence oil appears to be a convenient method of offering support and maintaining optimal health in middle aged women.

• 지역사회간호학회지
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• 제8권1호
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• pp.144-154
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• 1997

This study is planned to gather necessary data for setting up a system on students' health care in the university. In order to obtain statistical data on the students' health care problems especially in 'depression' among the mental health problems of the students, 'The Beck Depression Inventory' by A. T. Beck and 'Zung's Self-Rating Depression Scale' by W. W. K. Zung were used for gathering numerical data of scale of depression. It is evident that we have to prepare for further medical examination and health care educations for several students. For these students, it is clear that they have problems not only in mental health but also in physical health. I have screened out the high scored students for comparison and analysis. And it disclosed that we have to build up a periodical and continuous 'Health Screening System' utilizing Health Questionnaire for both physical and mental aspects, which will bring up us the very exact result to pick out any person who has healthy problem among the enormous number of the students with handy, convenient and effective procedures but with the least expense and effort. Also it is my firm confidence that this system will be applicable for primary health care control of mass population in local community or any organization.