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DETECTION OF METHICILLIN OR VANCOMYCIN-RESISTANT STAPHYLOCOCCUS AUREUS FROM DENTAL HOSPITAL (치과병원 진료실 내에서 메티실린 또는 반코마이신 저항성 Staphylococcus aureus의 검출)

  • Min, Jung-Hee;Park, Soon-Nang;Hwang, Ho-Keel;Min, Jung-Beum;Kim, Hwa-Sook;Kook, Joong-ki
    • Restorative Dentistry and Endodontics
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    • v.32 no.2
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    • pp.102-110
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    • 2007
  • The purpose of this study was to obtain the basic information for the improvement of dental environment by investigating the presence of methicillin- or vancomycin-resistant Staphylococcus aureus (MRSA or VRSA) isolated from dental health care workers (DHCWs) and environment of the Chosun University Dental Hospital (CUDH) and a private dental clinic (control group). Staphylococcus aureus (S. aureus) was isolated from anterior nares of 42 DHCWS and 38 sites, unit chairss, x-ray devices, computers, etc., at 10 departments of the CUDH and 20 DHCWs and 11 sites at the private dental clinic. S. aureus was isolated on mannitol salt agar plate and confirmed by PCR with S. aureus species-specific primer. Antimicrobial susceptibility test of clinical isolates of S. aureus against several antibiotics including methicillin (oxacillin) was performed by investigating minimum inhibitory concentration (MIC) using broth microdilution assay. In addition, PCR was performed to detect the methicillin- or vancomycin-resistant gene. The data showed that one strain of S. aureus was isolated from DHCWs of the CUDH and three strains of S. aureus was isolated from 3 samples of the private dental clinic, respectively. All of the isolates from the CUDH and the private dental clinic had resistance to penicillin G, amoxicillin and vancomycin and susceptibility to oxacillin and ciprofloxacin. The S. aureus strains were already obtained the resistance to penicillin G and amoxicillin. These results suggest that two dental clinics were under relatively safe environment.

한국수출산업을 위한 산업디자인 개선에 관한 연구 -시각.공예.제품디자인을 중심으로-

  • 박대순
    • Archives of design research
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    • v.1 no.1
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    • pp.1-162
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    • 1980
  • The Design Society of Korea. It is our urgent task that we should map out our detailed guiedlines for the improvement of export-oriented industries and of the design of export goods in preparation for our export goal of $30 billion in the upcoming 1980s. The government, university design researchers, and most entrepreneurs have confronted diverse kinds of racking issues: how much do most export industries take advantage of the indus-trial design for the improvement of the quality of export goods\ulcorner, structural defects of most export industries, chronic and vicious cycle of overlooking the value of the industrial design in the process of manufacturing export goods and etc. In other words, the recent trend of slighting the industrial design is to speed up the sales of only unsophisticated goods on the international markets. Although Koreans have been plagued by scantiness of natural resources under these circumstances, most Korean people have showed off their strong will for today's growth. Furthermore, most exporters should do their best to sweep overseas markets by manufacturing sophisticated goods outranking those commodi-ties made by the United States, Japan, West Germany and the other developed countries. In this respect, we have to make our best efforts for the expensive application and practical use of the industrial design, one of the comprehensive sciences, in the face of the hard realities and conditions which we have confronted until now. For example, it can be attributed to the practical application of the industrial design that the neighboring Japan, West Germany, France, the United Kingdom in Europe, and the United States in North America have formulated a highly advan-ced cultural zone and braced up for their own trade protection-ism and tightened their embargoes on EEC goods. Unless any export goods take the best advantage of the industrial design, one of the behavioral sciences capable of satisfying the material mental needs of modern men and of promoting cultural growth, I am convinced that they will not infiltrate into any countries that have enjoyed their own highly cultural lives. It is absolutely important that most Korean universities, state-run, private corporations and research institutes should work out the improvement strategy for the development and practical use of the industrial design as will as the revision of the present curricula of the departments of design. However, most design researchers have come to grips with several difficult problems such as the correlation of export oriented industries and the industrial design and the development of the design of export goods. The improvement of the industrial design is our urgent assignment that we have to solve in the 1980s. Accordimgly, I cannot too much emphasize the value the recognition of the industrial design in our industrial communities because we have never witnessed the prosperity of those countries which have taken little notice of the importance of the industrial design. Hopefully, most entrepreneurs will take much consideration of the value of the industrial design and then can defeat their rival businessmen on the international markets by exporting goods of highly sophisticated design. In this respect, the main purpose of the research paper which this society presented is to underline the fact that the improvement and development of the industrial design is our common assignment to be studied from the viewpoints of national dimension as well as in conformity with our immediate goal for the export-oriented prosperity of state. In conclusion, I would like to highlight the fact that our export goods shall be continually developed in pace with the correlative improvement of the indudtrial design so as to pave the way for their bright prospect and to enhance their best impression of the first-class goods on the international markets.

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A Study on the Transformation of Traditional Laboratories into Instructional Media Centers for Education of Library and Information Science (문헌정보학 실습실의 교수매체 센터화에 관한 연구)

  • Lee, Man-Soo
    • Journal of the Korean Society for Library and Information Science
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    • v.34 no.1
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    • pp.265-295
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    • 2000
  • Education of library and information science must focus on practical education acted upon as a laboratory room in the characteristics of learning, because it cultivates a librarian as an information expert who can conduct professional affairs and services, applying traditional theory to the practical business of library and information. This dissertation suggested a new paradigm of an instructional media center as an advanced laboratory room which faithfully can run the curriculum of a library and information science for cultivating librarians, information experts who can satisfy the 21C information society. To carry out this purpose, I considered the various opinions of professors and librarians, after investigating and analyzing facilities and furnishings of laboratory rooms and teaching and learning data related to departments of library and information science in 32 universities. These contents can be summarized as follows : 1) Constructional media centers connected to education of library and information science sets laboratory rooms for practical classification and cataloging classes; laboratory rooms for film media which can utilize advanced media, listening tools, and practical materials; information management laboratory rooms which can experience the various information research methods through the Internet, cultivate the ability of information application, and teach the curriculum of library and information science related to computers. 2) Arrangement plans linked to laboratory rooms for classification and cataloging, one for film media, and one for information proceedings are as follows: , , and . 3) The size of each room is $162m^2$ (49.1pying); the number of persons to be admitted is about 40 to 50; each room has one media expert and one assistant as operating manager of exclusive responsibility. 4) Instructional & learning data which must be contained as instructional media of library and information science include computers, marginal tools related to it, listening materials, supplies for ordering books, teaching aids containing various equipment and tools, textbooks for practice, books connected to classification and cataloging for practice, and textbooks related to practical subjects and reference books. 5) Industrial media centers belonging to library and information science require for practice, general furnishings like bookshelves, and various material depository boxes.

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Interaction of Ras-GTPase-activating Protein SH3 Domain-binding Proteins 2, G3BP2, With the C-terminal Tail Region of KIF5A (Ras-GTPase-activating protein SH3 domain-binding proteins 2, G3BP2와 KIF5A C-말단 꼬리 영역과의 결합)

  • Jeong, Young Joo;Jang, Won Hee;Lee, Won Hee;Kim, Mooseong;Kim, Sang-Jin;Urm, Sang-Hwa;Moon, Il Soo;Seog, Dae-Hyun
    • Journal of Life Science
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    • v.27 no.10
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    • pp.1191-1198
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    • 2017
  • Vesicles and organelles are transported along microtubule and delivered to appropriate compartments in cells. The intracellular transport process is mediated by molecular motor proteins, kinesin, and dynein. Kinesin is a plus-end-directed molecular motor protein that moves the various cargoes along microtubule tracks. Kinesin 1 is first isolated from squid axoplasm is a dimer of two heavy chains (KHCs, also called KIF5s), each of which is associated with the light chain (KLC). KIF5s interact with many different binding proteins through their carboxyl (C)-terminal tail region, but their binding proteins have yet to be specified. To identify the interacting proteins for KIF5A, we performed the yeast two-hybrid screening and found a specific interaction with Ras-GTPase-activating protein (GAP) Src homology3 (SH3)-domain-binding protein 2 (G3BP2), which is involved in stress granule formation and mRNA-protein (mRNP) localization. G3BP2 bound to the C-terminal 73 amino acids of KIF5A but did not interact with the KIF5B, nor the KIF5C in the yeast two-hybrid assay. The arginine-glycine-glycine (RGG)/Gly-rich region domain of G3BP2 is a minimal binding domain for interaction with KIF5A. However, G3BP1 did not interact with KIF5A. When co-expressed in HEK-293T cells, G3BP2 co-localized with KIF5A and was co-immunoprecipitated with KIF5A. These results indicate that G3BP2, which was originally identified as a Ras-GAP SH3 domain-binding protein, is a protein that interacts with KIF5A.

A Efficacy of One-Stop Service in the Outpatient Clinic at the University Medical Center (3차 의료기관 외래진료에 있어 One stop service 도입의 효과)

  • Lee, Suk-Yeon;Chang, Sung-Goo
    • Korea Journal of Hospital Management
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    • v.6 no.2
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    • pp.70-85
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    • 2001
  • This study has been conducted, on the reservation of specific examinations during seven months starting from June 1999 and ending December as the Group I for these of one stop service and as the Group II for those of existing direct reservation made by patients or patrons, to understand the differences between the two groups. The survey was extended to the patients visiting specific departments of K hospital with sample sizes of 154 for the Group I and 155 for the Group II. The findings of the survey are as follows: First, as the general characteristics of the sample, male patients account for 67% of the total and female patients 33%, with the former twice as large as the latter. The average age of the patients is 51, indicating relatively high level. By the geographical area of residence, metropolitan area is 80.7% and the other area 19.3%, showing most of the patients are from metropolitan area. The general characteristics do not have statistical significance between the Group I and the Group II(p>0.05). Second, regarding the ratio by the number of examinations, the Group I shows 37.0% for one examination and 63.0% for two examinations, while the Group IT indicates 30.3% for one examination and 69.7% for two examinations. The populations by the number of examinations do not have statistical difference between the two Groups(p>0.05). Third, regarding the time required for the reservation of examinations by the number of examinations, the Group I shows 9.8 minutes for one examination and 19.8 minutes for two examinations, with the average of 16.1 minutes. The Group IT indicates 19 minutes for one examinations and 25.7 minutes for two examinations, with the average of 23.7 minutes. Though the time required for the reservation by the number of examinations do not have statistical significance, the time required for the Group I was shortened. Fourth, regarding the time required for the reservation of examinations by the age range of patients, the Group I shows 21.7 minutes for 70-79 years of age, 17.5 minutes for 60-00 years of age, and 15.2 minutes for 30-39 years of age. The Group II indicates 27.2 minutes for 70-79 years of age, 26.3 minutes for 60-69 years of age, 24.4 minutes for 50-59 years of age, and 22.4 minutes for 30-39 years of age. The time required for the reservation gets longer as the age range moves up, and has statistical significance (p<0.05). Fifth, regarding the ratio by the range of time of required for reservation, the Group I shows 41.6% for 11-20 minutes, and 38.3% for 1-10 minutes, while the Group II indicates 43.9% for 11-20 minutes, 29% for 21-30 minutes, and 14.2% for 31-40 minutes. Statistical significance is revealed (p=0.001). Sixth, concerning the length of movement course by the number of examinations, the Group I shows 37 meters regardless of the number of examinations. The Group II indicates an average of 188 meters for one examination and 189 meters for two examinations, with the difference 151 meters between the Groups, and representing statistical significance (p=0.001). Based on the above findings. one-stop service contributes to the reduction of both the time and the movement course and therefore is considered to be beneficial to the patients, and the improve the efficiency of the hospitals in terms of the space and the time.

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A Study of the Department of Dental Hygiene and Dental Laboratory Technology Student's Demand for the Credit Bank System (학점은행제(치위생과, 치기공과)를 이용한 학사학위 취득에 관한 요구도 조사)

  • Yu, Ji-Su
    • Journal of dental hygiene science
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    • v.7 no.3
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    • pp.153-159
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    • 2007
  • To investigate requirements for the process of credit bank system in life-long education institutions attached to colleges, this research was conducted with seniors at the departments of dental hygiene and dental laboratory technology, in the health line of the specific College from March 26 to April 15, 2007, followed by analysis using an SPSS/WIN 12.0 program, obtaining the following results. 1. 89.7% of the respondents had a plan to take a bachelor's degree and 56.1% of whom had such a plan for the purpose of personal development (p<0.05). 2. 73.5% of the respondents preferred the credit bank system in a lifelong education institution attached to a college to take a bachelor's degree. 3. 34.8% presented the greatest advantage of taking a bachelor's degree through the credit bank system that they could take a degree in a short period of time while 33.8% presented the most serious disadvantage that they might low social recognition. 4. As for requirements for the process of operating the credit bank system, 80.3% regarded required subjects for the major as appropriate basic ones. 79.9% regarded it as proper that filling more than 20 credits made it possible to take a degree. 5. As directions for improving the system, it was found that the students was thinking that strict academic record management is needed, and the degrees from the system must be recognized equally to those in regular colleges, social awareness in those degrees should be enhanced, and also credits assigned to cultural subjects should be reduced, and the limitation in the number of credits being able to be obtained in one center should be removed.

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Evaluation of the Effect of Operation of Toothbrushing Room in between Two Elementary Schools (일부 초등학교 양치교실 운영 효과 평가)

  • Seong, Mi-Gyung;Kwun, Hyeon-Sook;Moon, Sook-Ryeon;Ryu, Hae-Gyum
    • Journal of dental hygiene science
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    • v.15 no.1
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    • pp.24-31
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    • 2015
  • This research was conducted in order to examine the effect of tooth brushing room M elementary school in Changwon-city and to provide foundation data for effective project operation afterwards. The subjects were 347 students at the M elementary school where the tooth brushing room was being taught. The control group is 289 students at J elementary school where the tooth brushing room was not being taught. Research and analysis were carried out with structured survey and examination of decayed, missing, filled teeth (DMFT) index, decayed, missing, filled tooth surface (DMFS) index and O'leary index. The data was analysed by IBM SPSS Statistics ver. 19.0 program and the result is as follows: Depends on the tooth brushing room there was difference in statistical significance in filling teeth, sealant tooth surface, filling tooth surface, missing tooth surface, DMFS, O'leary index between the subject and control group. The less the frequency of brushing, the higher the DMFT index. Negative correlation was statistically significant. With incorrect brushing method, the less the frequency, the higher the DMFS index, Negative correlation was statistically significant. When the tooth brushing room was being implemented, O'leary index became low, negative correlation was statistically significant. As a result, in order to continue the effective operation of tooth brushing room, constant supervision and monitoring on students should be acutely needed by a principal, a school nurse and teachers in charge. Also together with a systemized cooperation between a health center and a nearby university's related majors departments, the research proposes to execute constant oral health education and to expand the implementation project of the tooth brushing room at nearby elementary schools.

Predictable risk factors and clinical courses for prolonged transient tachypnea of the newborn (지속성 신생아 일과성 빈호흡을 예측하게 하는 위험인자와 임상경과)

  • Chang, Ji Young;Kim, Chang Ryul;Kim, Ellen A;Kim, Ki Soo
    • Clinical and Experimental Pediatrics
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    • v.53 no.3
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    • pp.349-357
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    • 2010
  • Purpose : Transient tachypnea of the newborn (TTN) is usually benign and improves within 72 hours. However, it can also progress to prolonged tachypnea over 72 hours, profound hypoxemia, respiratory failure, and even death. The aim of this study is to find predictable risk factors and describe the clinical courses and outcomes of prolonged TTN (PTTN). Methods : The medical records of 107 newborns, >$35^{+0}$ weeks of gestational age with TTN, who were admitted to the NICU at Seoul Asan Medical Center from January 2001 to September 2007 were reviewed. They were divided into 2 groups based on duration of tachypnea. PTTN was defined as tachypnea ${\geq}72$ hours of age, and simple TTN (STTN) as tachypnea <72 hours of age. We randomly selected 126 healthy-term newborns as controls. We evaluated neonatal and maternal demographic findings, and various clinical factors. Results : Fifty-five infants (51%) with total TTN were PTTN. PTTN infants had grunting, tachypnea >90/min, $FiO_2$ >0.4, and required ventilator care more frequently than STTN infants. PTTN had lower level of serum total protein and albumin than STTN. The independent predictable risk factors for PTTN were grunting, maximal respiration rate >90/min, and $FiO_2$ >0.4 within 6 hours of life. Conclusion : When a newborn has grunting, respiration rate >90/min, and oxygen requirement >0.4 of $FiO_2$ within 6 hours of life, the infant is at high risk of having persistent tachypnea ${\geq}72$ hours. We need further study to find the way to reduce PTTN.

Application Plan of Goods Information in the Public Procurement Service for Enhancing U-City Plans (U-City계획 고도화를 위한 조달청 물품정보 활용 방안 : CCTV 사례를 중심으로)

  • PARK, Jun-Ho;PARK, Jeong-Woo;NAM, Kwang-Woo
    • Journal of the Korean Association of Geographic Information Studies
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    • v.18 no.3
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    • pp.21-34
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    • 2015
  • In this study, a reference model is constructed that provides architects or designers with sufficient information on the intelligent service facility that is essential for U-City space configuration, and for the support of enhanced design, as well as for planning activities. At the core of the reference model is comprehensive information about the intelligent service facility that plans the content of services, and the latest related information that is regularly updated. A plan is presented to take advantage of the database of list information systems in the Public Procurement Service that handles intelligent service facilities. We suggest a number of improvements by analyzing the current status of, and issues with, the goods information in the Public Procurement Service, and by conducting a simulation for the proper placement of CCTV. As the design of U-City plan has evolved from IT technology-based to smart space-based, reviews of limitations such as the lack of standards, information about the installation, and the placement of the intelligent service facility that provides U-service have been carried out. Due to the absence of relevant legislation and guidelines, however, planning activities, such as the appropriate placement of the intelligent service facility are difficult when considering efficient service provision. In addition, with the lack of information about IT technology and intelligent service facilities that can be provided to U-City planners and designers, there are a number of difficulties when establishing an optimal plan with respect to service level and budget. To solve these problems, this study presents a plan in conjunction with the goods information from the Public Procurement Service. The Public Procurement Service has already built an industry-related database of around 260,000 cases, which has been continually updated. It can be a very useful source of information about the intelligent service facility, the ever-changing U-City industry's core, and the relevant technologies. However, since providing this information is insufficient in the application process and, due to the constraints in the information disclosure process, there have been some issues in its application. Therefore, this study, by presenting an improvement plan for the linkage and application of the goods information in the Public Procurement Service, has significance for the provision of the basic framework for future U-City enhancement plans, and multi-departments' common utilization of the goods information in the Public Procurement Service.

Bone Metastasis after a Curative Resection for Gastric Cancer (위암의 근치적 절제술 후 발생한 골 전이)

  • Kim Jin Jo;Song Kyo Young;Chin Hyung Min;Kim Wook;Chun Hae Myung;Park Cho Hyun;Park Seung Man;Park Woo Bae;Lim Keun Woo;Kim Seung Nam
    • Journal of Gastric Cancer
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    • v.5 no.1
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    • pp.23-28
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    • 2005
  • Purpose: Bone metastasis is not a common event in patients with gastric cancer. Therefore, most studies of bone metastasis in such patients have been in the form of case reports, so the clinical features of the bone metastasis are not well understood. To clarify metastatic patterns, the efficacy of radiation or chemotherapy, and the prognosis, we analyzed 29 cases of patients with bone metastases after curative surgery for gastric cancer. Materials and Methods: Twenty-nine (29) gastric cancer patients with bone metastasis who underwent curative resection from January 1989 to December 2002 at the Departments of Surgery, Kangnam St. Mary's Hospital and Our Lady of Mercy's Hospital, The Catholic University of Korea, were analyzed. Results: Nineteen (19) patients were males and, 10 patients were females. The mean age of the patients was $53\pm12$ years. There were more Borrmann type-3 and type-4 cancers and more undifferentiated histologic types. Most of the original cancers were stage III or IV. The most frequently involved bone was the spine. Treatment after recurrence was done in 16 patients ($55.2\%$). The median survival time after recurrence of the patients who received treatment was seven (7) months ($0\∼75$ months in range), which was significantly longer than that of the patients who did not received treatment (P=0.019). However, there was no difference according to the treatment modality (P=0.388). Conclusion: Bone metastasis after a curative resection of gastric cancer tends to occur in Borrmann type-3 and type-4 cancers, cancers with undifferentiated histology and, in stage III/IV disease. The prognosis of bone metastasis is dismal, and aggressive treatment is the only way to prolong survival.

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