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Analysis of Existing Guidelines and Controlled Clinical Trials for Development of [Guideline of Clinical Trials with Herbal Medicinal Products for Colorectal Cancer] (결장직장암 한약제제 임상시험 가이드라인 개발을 위한 한약제제 대조군 임상시험 고찰)

  • Park, Eunjoo;Seong, Sin;Kim, Sungsu;Kim, Jinsung;Park, Jae-Woo;Ko, Seok-Jae;Han, Gajin
    • The Journal of Korean Medicine
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    • v.40 no.1
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    • pp.124-152
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    • 2019
  • Objectives: This study aimed to ascertain what should be considered in the "Guideline for Clinical Trials with Herbal Medicinal Products for Colorectal Cancer" by analyzing the existing guidelines and clinical trials. Methods: The development committee searched guidelines for herbal medicinal products for colorectal cancer that have already been developed. Then, clinical trials for colorectal cancer using herbal medicine were searched. The searched trials were analyzed in terms of inclusion and exclusion of participants, intervention, comparator, outcomes and trial design. Then, we compared the results of our analysis with the regulations and guidelines of the Ministry of Food and Drug Safety in order to identify the issues we will have to consider when making the "Guideline for Clinical Trials with Herbal Medicinal Products for Colorectal Cancer". Several guidelines for anti-tumor agents and clinical trials with herbal medicinal products were searched on the national institution homepage. In addition, 12 articles were searched using a combination of the following search terms: 'colorectal neoplasms', 'herbal medicine', 'Medicine, Korean traditional', 'Medicine, Chinese Traditional', 'medicine, East Asian medicine', 'medicine, Kampo', etc. Results: The characteristics of participants were various, such as people with medical histories of surgeries or recurrent cancers or who complained of chemotherapy-induced side effects. The types of interventions were also various and included decoctions, powders, intravenous fluids, intraperitoneal injections and gargles. Comparators used included placebos and conventional treatments. The outcome measurements used in the studies were quality of life, symptom score, tumor response, and survival duration, etc. Safety was evaluated by recording adverse events. Conclusions: Findings were made by reviewing existing guidelines and comparing them with clinical trials for colorectal cancer and herbal medicinal products. These results will be utilized in the development of the "Guideline for Clinical Trials with Herbal Medicinal Products for Colorectal Cancer".

The Effect of Corporate Social Responsibility on Organizational Trust, Job Satisfaction and Turnover Intention (건설기업의 사회적 책임 활동이 조직신뢰, 직무만족과 이직의도에 미치는 영향)

  • Cho, Jin-Ho;Kim, Byung-Soo
    • Korean Journal of Construction Engineering and Management
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    • v.20 no.5
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    • pp.83-94
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    • 2019
  • Recently, the proportion of overseas orders of domestic construction companies is increasing, and the global market demands management transparency on corporate social responsibility activities. Therefore, domestic companies are faced with the need to systematically prepare for social responsibility activities. The purpose of this study was to examine whether CSR activities have a moderating effect on the relationship between organizational trust, job satisfaction, turnover intention and contract type. This study analyzed the effect of CSR activities on organizational trust, job satisfaction and turnover intention. The study targets regular and irregular workers in construction companies who promote CSR activities through the homepage, public service ad, and media. The questionnaire distributed 300 copies online. The final valid sample is 255 (145 Regular and 110 Irregular). Empirical analysis used a structural equation model. The results of the study are as follows. First, in CSR activities, economic responsibility, philanthropic responsibility and ethical responsibility had a positive (+) effect on organizational trust. Second, organizational trust had a positive (+) effect on job satisfaction in CSR activities. Finally, the magnitude of the Moderate effect of the type of labor contract according to the group classification showed that the CSR activity on organizational trust had many regular employees with economic responsibility. Also, organizational trust in job satisfaction was found to be large in regular employees. The results of this study can be a guide to CSR activities of construction companies in terms of organizational effectiveness.

Color Image Enhancement Based on an Improved Image Formation Model (개선된 영상 생성 모델에 기반한 칼라 영상 향상)

  • Choi, Doo-Hyun;Jang, Ick-Hoon;Kim, Nam-Chul
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.43 no.6 s.312
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    • pp.65-84
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    • 2006
  • In this paper, we present an improved image formation model and propose a color image enhancement based on the model. In the presented image formation model, an input image is represented as a product of global illumination, local illumination, and reflectance. In the proposed color image enhancement, an input RGB color image is converted into an HSV color image. Under the assumption of white-light illumination, the H and S component images are remained as they are and the V component image only is enhanced based on the image formation model. The global illumination is estimated by applying a linear LPF with wide support region to the input V component image and the local illumination by applying a JND (just noticeable difference)-based nonlinear LPF with narrow support region to the processed image, where the estimated global illumination is eliminated from the input V component image. The reflectance is estimated by dividing the input V component image by the estimated global and local illuminations. After performing the gamma correction on the three estimated components, the output V component image is obtained from their product. Histogram modeling is next executed such that the final output V component image is obtained. Finally an output RGB color image is obtained from the H and S component images of the input color image and the final output V component image. Experimental results for the test image DB built with color images downloaded from NASA homepage and MPEG-7 CCD color images show that the proposed method gives output color images of very well-increased global and local contrast without halo effect and color shift.

Implementation of Real-time Book Search Service of Library using OpenAPI (OpenAPI를 이용한 실시간 자치도서관 도서검색 서비스구현)

  • Lim, Dae-Hyun;Park, Jin-Tae;Lee, Hye-Rim;Jeong, Jae-Pil;Moon, Il-Young
    • Journal of Advanced Navigation Technology
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    • v.13 no.5
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    • pp.793-798
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    • 2009
  • In this paper, the performances of implementation real-time book search service of government library using OpenAPI. Since 2000, each self-government made a governmnt library for local resident because of policies to encourage reading. Each self-government library services book perusal and lend free for local resident. In current system local residents visit to a library for lending, returning and reading books. And each library run by a self-governing administration provides their own homepage for searching service as well as booking. For each services are not unified, however, it is not easy for lenders to search and lend these enormous books which are spread each library. Accordingly, we present a plan which using organization of every system established now in each library as it is, for a scheme of database by libraries' efficient unification and search, a network of TCP/IP and application which connects each library's database, servicing which uses Open API a check books through real time accessing Database.

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Survey and Analysis on Computer Using Ability of Early Childhood for Developing Educational Software (교육용 소프트웨어 개발을 위한 영유아 컴퓨터 활용 능력에 대한 실태조사 분석)

  • Choung, Hye-Myoung;Song, Joo-Seung
    • Journal of the Korea Society of Computer and Information
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    • v.15 no.10
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    • pp.209-220
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    • 2010
  • In this study, a survey was carried out to investigate status of children's computer use and their ability by gender and age. The objects of the survey were kids at a day care center in Gimpo where students of the early childhood education department of K university had practical training for a month. 378 questionnaire were collected excepting those with insincere or inconsistent responses, and among them, According to the results of this study, girls use computers more often than boys for educational purposes such as learning how to read and write Korean language and numbers and foreign languages, and also learning music and arts. On the other hand, boys use computers more often than girls for entertainment like cartoon movies and games. In terms of computer using ability such as understanding instructions, manipulation of functions, drawing pictures, chatting and e-mail, internet shopping, homepage making, girls have higher ability than boys while boys are significantly superior to girls in the ability to play computer games. The analytical results show that application programs of the childhood education is desirable for boys to use for the sake of arousing the interest and for the game and for girls to use at the part of music and arts. According to ages, for 1-2 years children, they needs the AP with a delicate person having the computer knowledge, for 3-4 years children, they need AP with some little help, for 6-7 years, they need the AP to do themselves according to sex and age.

A Geographical Study on Characteristics of Political Activities in Cyberspace and Interrelationship between Online and Offline: A case of South Korea's Presidential Election in 2012 (가상공간에서의 정치 활동의 특징과 오프라인 환경과의 연계성에 대한 지리적 고찰: 2012년 대통령 선거를 사례로)

  • Park, Sookyung
    • Journal of the Korean Geographical Society
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    • v.48 no.5
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    • pp.686-708
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    • 2013
  • The goal of this investigation is to examine the matter as to how various cyberpolitical activities such as on-line civic participation, cyber parties, development and movement of civil society networks are appeared in cyberspace; and how political activities in cyberspace are associated with offline environment. This research was based on in-depth and open-ended interviews centering around 20s (32 interviewees) and the major results are as in the following. First, in terms of on-line civic participation, searching political issues occur in places, where internet users can access information easily relatively, and creating or reconstructing political information is identified in places giving stability or affinity to the public society. Second, even though each party's homepage for the channel of cyber parties has enough capacity as bridgespace, which takes charge of supporting f lows of people, goods, capital, and ideas, most of them don't play a role to establish virtual or real networks. Exceptively, cyber parties contribute to make temporalized places, where nobody takes the responsibility, somewhat. Third, the development and movement of civil society networks is divided into several segments according to political interests and tendency in online; furthermore, such a cyberpolitical activity influences human networks and the decision of major places for political activities in offline.

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The Recognition Comparison for the Utilization State of Smart Devices and Culinary Education Application Development of High School Students (고등학생의 스마트 기기 활용 실태와 조리교육 애플리케이션 개발에 대한 인식 비교 연구)

  • Kang, Keoung-Shim
    • Journal of Digital Convergence
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    • v.10 no.11
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    • pp.619-626
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    • 2012
  • The purpose of this study is to compare and analyze the utilization state of smart devices and the recognition level of educational application development of the general high school and the specialized high school. Specialized high school students preferred the utilization of smart devices more and daily spent on the devices more time than general high school students. As for the learning field, language for the general high school and the certificate of qualification for the specialized high school were shown high. The merit of smart device utilization is the use of spare time and its infrastructure was most required. The most expected content is a video lecture for the general high school and cooperative learning for the specialized high school and the most satisfied point was mobility. The specialized high school students feel more necessity about the application development for culinary education and had a plan to utilize it more and more preferred practice videos. As for the food development areas, the general high school students hoped simple food and the specialized high school students did cooking technician food and they both hoped the application to be uploaded in portal sites and the department homepage. The application development for culinary education is required to focus simulation learning including practice videos and cooking recipes and add an evaluation function to check the academic achievement levels. It is required to provide the subject goals of each course and concrete information on solving problems. Contents including video, music, texts need to be attached to improve learning immersion. There should be the beginning and development of a lesson and the flow of arrangement and communication between main bodies of learning should be improved by utilization of SNS cooperative learning services.

Strategic Approaches to Solid Ranking International Journals: KODISA Journals (국제저널 육성 방향과 전망: KODISA Journals를 중심으로)

  • Youn, Myoung-Kil;Kim, Dong-Ho;Lee, Jong-Ho;Hwang, Hee-Joong;Lee, Jung-Wan
    • Journal of Distribution Science
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    • v.12 no.6
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    • pp.5-13
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    • 2014
  • Purpose - The purposes of this editorial review are twofold: firstly, to introduce the four flagship international journals of the Korea Distribution Science Association(KODISA): the Journal of Distribution Science(JDS), the Journal of Industrial Distribution & Business(JIDB), the East Asian Journal of Business Management(EAJBM), and the Journal of Asian Finance, Economics and Business(JAFEB), and secondly, to identify the direction of the KODISA journals and the roles and responsibilities of the editors of the KODISA journals. Research design, data, and methodology - To achieve the goals, firstly, this review paper addresses the current progress of the four KODISA journals: JDS, JIDB, EAJBM, and JAFEB. Secondly, this paper defines the aims and missions of the four KODISA journals. JDS publishes the articles of examining past, current, and emerging trends and concerns in the area of distribution science and economics, logistics and SCM, transportation, distribution channel management, distribution innovation and information technology, merchandising and procurement, distribution and marketing, consumer behavior, and manufacturing, wholesaling, and retailing. JDS publishes both quantitative and qualitative research as well as scholarly commentaries, case studies, book reviews and other types of reports relating to all aspects of distribution. JIDB publishes the articles of examining past, current, and emerging trends and concerns in the areas of industry and corporate behavior, industry policy making, industrial distribution and business, e-commerce, and service industry. EAJBM publishes empirical and theoretical research papers as well as scholarly commentaries, case studies, book reviews, and other types of reports relating to all aspects of East Asian business and economy. JAFEB publishes original research analysis and inquiry into the contemporary issues of finance, economics and business management in Asia, including Central Asia, East Asia, South Asia, Southeast Asia, and Middle East. The mission of JAFEB is to bring together the latest theoretical and empirical finance, economics and business management research in Asian markets. The audiences of the KODISA journals include higher education institutions, scholars, industry researchers and practitioners, scientists, economists, and policy makers throughout the world. The main mission of the KODISA journals is to provide an intellectual platform for international scholars, promote interdisciplinary studies in social sciences and economics, and become leading journals in the social science and economics category in the world. Thirdly, this paper addresses the current status of indexing in major databases of the KODISA journals, namely: Cabell's Directories, EBSCO, SCOPUS (Elsevier), and Social Sciences Citation Index® (SSCI, Thomson Reuters). Fourthly, this paper identifies the roles and responsibilities of the editors of the KODISA journals as the following: (1) Make sure that the journal be published in a timely manner and in international standards both in print and online versions. (2) Maintain the online homepage of the journal is always accessible to, and (3) Make sure that every article should go through a peer review process that meets international standards. Findings and conclusion - To accomplish the goals and missions of the KODISA journals, the editors of the KODISA journals must work together to publish high scholarly journals that meet international standards of journal publications.

A Study on the Attracting Strategy of FDI in Gwangju and Jeonnam Region (외국인직접투자 유치전략에 관한 연구 -광주.전남지역을 중심으로-)

  • Shim, Jae-Hee;Baek, Hyung-Yeop
    • International Commerce and Information Review
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    • v.13 no.1
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    • pp.145-175
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    • 2011
  • This paper suggests the strategy for attracting FDI in Gwangju and Jeonnam region using the secondary data collected by homepage of Ministry of Knowledge Economy, Gwangju City, and Jeollanam-do. The strategy for attracting FDI in Gwangju and Jeonnam region is as follows: First, the local governments of Gwangju and Jeonnam must progressively attract FDI by adjusting to the Korean government's regional industry policy direction. Second, in order to attract FDI consistently, the local governments of Gwangju and Jeonnam must enhance the ability of local officials to attract FDI. Third, in order to attract FDI effectively, the local governments of Gwangju and Jeonnam must build a complete system to support FDI. Fourth, in order to attract FDI effectively, the local governments of Gwangju and Jeonnam have to apply different investment incentives according to FDI effectiveness. Fifth, the local governments of Gwangju and Jeonnam must consistently support foreign companies in order to induce FDI expansion by foreign companies which have already invested in the Gwangju and Jeonnam regions. Finally, in order to attract FDI consistently, the local governments of Gwangju and Jeonnam must improve the negative images and living environments of the Gwangju and Jeonnam regions.

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Role of Korean Society of Pediatric Infectious Disease during the Middle East Respiratory Syndrome (MERS) Outbreak in Korea, 2015 (2015년 우리나라에서 발생한 중동호흡기증후군과 대한소아감염학회의 역할)

  • Kim, Kyung-Hyo
    • Pediatric Infection and Vaccine
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    • v.22 no.3
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    • pp.136-142
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    • 2015
  • The Korean Society of Pediatric Infectious Diseases (KSPID) has participated in the task force team consisting of government authorities as well as civil medical experts and facilities to block the spread of Middle East Respiratory Syndrome in 2015. KSPID posted the "Middle East Respiratory Syndrome (MERS) Pop-up" in the homepage of The Korean Pediatric Society and The Korean Society of Pediatric Infectious Diseases. KSPID also released the "Guidelines for testing for MERS in children and adolescents" and the "Instructions for the Operation of National Safe Hospital" for children and adolescents in a timely manner. Such actions were aimed to prevent unnecessary anxieties, studies and isolation of pediatric patients with respiratory symptoms and signs caused by other common microbial etiologies as being suspected for MERS patients. This strategy relieved the doctors and parents from unnecessary fear and prevented the loss of unnecessary health care costs, and has proven to be a well-judged guideline and management protocol as evaluated after the final end of MERS outbreak. KSPID and its members should support the presence of pediatric infectious disease (PID) specialists in every medium size hospitals in Korea by developing the need for consultation fees for PID consultation in the hospital based practice and promoting the potential for cost savings related to prevention of health care associated infections and optimal prescription of antimicrobial agents. KSPID and its members need to approach and develop a communication plan to political decision makers to demonstrate and convince them of the importance of a PID specialist service.