• Restorative Dentistry and Endodontics
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• 제25권3호
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• pp.459-473
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• 2000

Dental caries is the most common disease in the maxillofacial area. There are many factors contributing to its development, but complete understanding and prevention is not fully known. Since the structure of the coronal and root portion of the tooth is different, the remineralization and demineralization process is also known to be different. In this study, by using a partially saturated buffer solution, we created artificial enamel and dentin caries and evaluated mineral loss. A remineralization solution with four different degrees of saturation (degree of saturation ; group 1, 0.268, group 2, 0.309, group 3, 0.339, group 4, 0.390, PH 4.3, F-2ppm) was used on a demineralized specimen. The mineral precipitating quantity and depth was evaluated by using microradiography. Using an atomic force microscope (AFM), hydroxyapatite crystals of normal, demineralized, and remineralized enamel and dentin were evaluated. The results were as follows: 1. As the degree of saturation of the remineralizing solution increased, the mineral precipitation in the enamel was increased. In group 4, mineral precipitation was limited near the surface. 2. As the degree of saturation of the remineralizing solution increased, the mineral precipitation in the dentin was decreased and it occurred in a deeper portion. In group 4, however, mineral precipitation occurred on the surface and its quantity increased. 3. There was a statistically significant interaction between enamel and dentin mineral content changes on specimens treated with remineralization and demineralization solution (demineralization r=0.44, remineralization r=0.44, p<0.05). 4. Demineralized hydroxyapatite crystals showed central and peripheral dissolving and widening of intercrystal spaces under the AFM. 5. In dentin remineralization small crystal precipitation occurred between the large crystals. We conclude that by adjusting acidulated buffer solution's degree of saturation, we can control enamel and dentin remineralization. In addition, the AFM is highly useful in evaluating changes in remineralized and demineralized hydroxyapatite crystals.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제23권1호
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• pp.82-86
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• 2001

저자 등은 하악 우측 제3대구치 발거 후 발치와를 통해 하악골에 이환되어 발생한 경안부 방선균증에서 병소부의 적출술과 소파술을 시행하고, 항생제 요법 및 개방창 유지등의 방법을 통해 양호한 경과를 보였기에 문헌고찰과 함께 보고하는 바이다.

• 대한치과마취과학회지
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• 제10권2호
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• pp.197-202
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• 2010

Multiple sclerosis is a degenerative disease prevalent in northern climates, and its cause is unknown. The histopathological lesion in multiple sclerosis is the sclerotic "plague", a discrete focus of myelin loss with maintenance of axon segments and glial proliferation. The plaques may be seen in widely different brain and spinal tissues. The common causes of low back pain are psychosomatic disorder, myofascial pain dysfunction syndrome and herniation of nucleus pulposus. Local anesthetics cross the blood-brain barrier and the signs of CNS toxicity appear at a level between 4.5 and $7.0\;{\mu}g/ml$. This is a case report of acute back pain care after mandibular block anesthesia for the surgical extraction of mandibular root rests in an old aged woman with multiple sclerosis.

• Restorative Dentistry and Endodontics
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• 제46권3호
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• pp.38.1-38.13
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• 2021

The elimination of endodontic biofilms and the maintenance of a leak-proof canal filling are key aspects of successful root canal treatment. Several materials have been introduced to treat endodontic disease, although treatment success is limited by the features of the biomaterials used. Silver nanoparticles (AgNPs) have been increasingly considered in dental applications, especially endodontics, due to their high antimicrobial activity. For the present study, an electronic search was conducted using MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar, and EMBASE. This review provides insights into the unique characteristics of AgNPs, including their chemical, physical, and antimicrobial properties; limitations; and potential uses. Various studies involving different application methods of AgNPs were carefully examined. Based on previous clinical studies, the synthesis, means of obtaining, usage conditions, and potential cytotoxicity of AgNPs were evaluated. The findings indicate that AgNPs are effective antimicrobial agents for the elimination of endodontic biofilms.

• 대한소아치과학회지
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• 제48권1호
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• pp.50-63
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• 2021

소두증 골형성이상 원발성 왜소증 제 II 형(MOPD II)은 원발성 왜소증의 일종으로 pericentrin 유전자의 돌연변이에 의해 유발되며 상염색체 열성으로 유전된다. 이번 연구는 MOPD II의 임상적 및 방사선학적 소견과 더불어 치아의 물리화학적 특성 및 미세구조에 대한 분석을 목적으로 하였다. MOPD II 환자의 발치된 하악 제2대구치를 대상으로 하였으며 미세 전산화 단층 촬영, 주사형 전자 현미경과 에너지 분산형 분광분석법 및 비커스 미세경도 분석을 이용하여 분석하였다. MOPD II 치아는 정상 치아와 비교 시 치근 및 치수의 이형성을 보였으며 크기가 작았다. 치아의 무기질 밀도는 법랑질에서는 비슷한 값을 보였으며 상아질에서는 치근 1/2 및 치근단 부위에서 MOPD II 치아가 정상 치아보다 작게 나타났다. 미세경도의 비교 시 교두 법랑질과 치근 1/2 및 치근단 부위의 상아질에서 MOPD II 치아의 미세경도가 정상 치아보다 작게 나타났다. 이 연구에서는 MOPD II의 치과적인 특징 및 치아의 물리화학적 특성에 대하여 분석함으로써, 질환의 구강 내 소견에 대한 이해도를 높이고 치과 치료 시 주의점을 확인하여 적절한 치료를 하는데 도움이 되고자 하였다.

• Journal of Periodontal and Implant Science
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• 제27권3호
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• pp.495-514
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• 1997

The purpose of this study was to evaluate the in vitro effects of Nd:YAG laser irradiation on removal of a root surface smear layer after root planing in comparison with Tetracycline HCl. The 60 extracted human teeth due to severe periodontal disease were vigorously scaled and root planed with Gracey curet. Thirty specimen($5{\times}5{\times}2mm$) were obtained from root planed surface of 30 human teeth and assigned randomly to one of three groups : root planed group(5 specimen), Tetracycline HCI group(5 specimen, burnished for 5 minutes), and Nd:YAG laser group(25 specimen, German Dental Laser, Fotona Twinlight). Nd:YAG laser group was divided into 4 subgroups according to power of 1W, 1.5W, 2W, 3W at frequency to 10Hz. The specimen were then fixed, and examed by Scanning electron microscopic study. 30 of 60 human teeth used to measurement of the intrapulpal temperature rise during laser irradiation. Laser-irradiated surface exhibited various surface texture from relative flat surface to irregular surface with patent dentinal tubules of various shape and size. In some area, the root surface alteration which are carbonization, pit and crater formation and melting and resolidification were observed. The number of exposed dentinal tubules per unit($100_{\mu}m^2$) on tetracycline HCI group was more than that in the laser group below 1.5W of power(150mJ/pulse) and was significantly less than that in laser group above 2W of power(200mJ/pulse)(P<0.OOl). As power increased the intrapulpal temperature rise also increased. The result suggested that the parameter which effectively remove root surface smear layer than tetracycline HCI may cause thermal damage to pulp and root surface alteration result from laser exposure would indicate need for additional instrumentation. Thus, Nd:YAG laser irradiation in these parameter may not be appropriate for clinical use as adjunct to conventional periodontal therapy.

• Journal of Periodontal and Implant Science
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• 제40권4호
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• pp.164-171
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• 2010

Purpose: This study compared the total antioxidant status (TAS) and superoxide dismutase (SOD) activity in the saliva of periodontally compromised patients before and after scaling and root planing (SRP) to assess their diagnostic utility. Methods: Severe chronic periodontitis patient (test group) and subjects with no attachment loss, sites showing a 3 mm or more probing depth and a sulcus bleeding index < 10% (control group) were enrolled in this study. Saliva sampling and clinical examination were performed at one week, one month and 3 months after SRP. The TAS and SOD activity in each patient's saliva was measured for the comparative analysis between the groups. Results: In the test group, the TAS decreased directly after SRP. With time, it increased slightly and was relatively unchanged compared to the baseline. In the control group, the TAS also decreased immediately after SRP but increased gradually with time until 3 months. The SOD activity in the test and control subjects decreased immediately after SRP until 1 month. At 3 months, the SOD activity had increased. Both groups had a similar profile of SOD activity. However, the SOD activity of the control group was significantly higher than that of the test group at each point in time (P < 0.05). Conclusions: There was a significant difference in the total salivary antioxidant level between the periodontitis and healthy or gingivitis (control) group during the experiment period. The total antioxidant level in the saliva was higher in the patients with severe chronic periodontitis than the healthy or gingivitis control before SRP. The SOD activity of the periodontitis patients was lower than the control at each time point. These findings conclusively reveal the possible use of saliva as a diagnostic tool for periodontal health.

• 대한치과보존학회:학술대회논문집
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• 대한치과보존학회 2003년도 제120회 추계학술대회 제 5차 한ㆍ일 치과보존학회 공동학술대회
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• pp.591-591
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• 2003

Apical periodontitis is inflammation of the periodontium caused by infection of the pulp canal system. Moreover, a dental periradicular lesion occurs as a periradicular tissue reaction to bacterial infection and consists of periradicular inflammation with alveolar bone destruction and root resorption, a consequence of the interaction between oral flora and the existing host defenses. Many investigations dealing with the pathogenesis and history of periradicular lesions have described histologically, immunologically, biochemically the development of the periradicular lesion；but none of these studies have shown any correlation between this lesion and several factors, the whole body disease in the worldwide.(omitted)

• Journal of Oral Medicine and Pain
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• 제33권1호
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• pp.15-26
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• 2008

다양한 전신질환으로 입원한 환자들 중에서 구강질환을 진료받기 위해서 내원한 환자의 전신질환 상태와 치과적인 주소 및 진단명 그리고 치료내용을 조사하고 이와 관련된 구강내과적인 주소가 무엇인지를 관찰함으로써 입원한 전신질환자와 구강질환과의 상관관계를 파악하고자 본 연구를 시행하여 다음과 같은 결론을 얻었다. 1. 구강질환을 진료받기 위해서 내원한 환자의 전신질환은 인슐린-비의존성 당뇨병 26%, 뇌경색 25.2%, 뇌내출혈, 다발성 관절증, 고관절증 각각 4.7%, 신경근 및 신경총 장애, 고혈압성 심장 및 신장 질환, 강직성 척추염 각각 2.4% 등의 순서로 나타났다. 2. 내원한 환자의 주소는 치통 28.6%, 정기검사 23%, 치아동요 8.7%, 치아지각과민 7.1%, 치주출혈 6.4% 등의 순서로 나타났다. 3. 내원한 환자의 진단된 구강질환은 치은염 및 치주질환 28.9%, 치아우식증 17.1%, 치수 및 치근단주위의 질환 15.1%, 타액선의 질환 10.5%, 치아경조직의 기타질환 8.6% 등의 순서로 나타났다. 4. 내원한 환자의 치료내용은 치주치료 17.95%, 치료거부 16.67%, 구강건조 및 구취 제거를 위한 약물치료 13.46%, 발치치료 12.18%, 보철치료 8.97% 등의 순서로 나타났다. 5. 내원한 환자의 구강내과적인 주소는 16% 이었으며, 구강연조직질환 6.4%, 두개하악장애 5.6% 그리고 구취 4% 등의 순서로 나타났다. 이상의 결과로 입원한 전신질환자를 통해서 전신질환이 있는 환자의 구강질환과 구강질환이 있는 환자의 전신질환에 대해서는 일정부분 파악이 되었으나 향후 구강질환과 전신질환과의 상관관계에 대한 연구가 계속적으로 이루어져야 한다고 사료된다.

• 대한소아치과학회지
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• 제31권2호
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• pp.262-266
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• 2004

부갑상선 호르몬은 혈중 인농도를 낮추고, 칼슘농도를 증가시키는 호르몬으로 부갑상선기능저하증은 부갑상선이 존재하지 않거나 비정상적으로 기능하여 이 호르몬의 분비가 감소되는 질환이며, 가성부갑상선기능저하증은 부갑상선 호르몬 분비는 정상이나, 이 호르몬에 대한 골과 신장의 반응이상으로 혈중 칼슘 농도가 감소되고 인농도가 증가되는 질환이다. 가성부갑상선기능저하증은 임상적으로 성장 및 발육부전, 둥근 얼굴, 조기 골단폐쇄로 인한 단지증, 이소성 연조직 석회화, 비만, 두개관의 비후, 정신지체, 백내장 등이 나타난다. 구강내 소견으로는 치아의 맹출지연, 법랑질형성부전이 가장 큰 특징이며, 그 외에 결손치, 부정교합, 높은 구개궁, 확장된 치근관과 짧은 치근, 치수강 내 석회화, 높은 우식 이환율 치근막의 비후 등이 관찰된다. 본 증례에서 환아의 구강내 소견은 맹출한 하악 4전치와 상악 좌우측 영구 중절치, 상악 우측 영구 측절치, 상, 하악 제 1대구치에서 법랑질형성부전을 보였고, 다수의 유치에서 심한 동요도를 보였다. 방사선 소견으로는 대부분의 미맹출된 영구치들도 법랑질형성부전이 관찰되었으며, 특히 영구 견치의 경우 심한 치관의 형태이상을 볼 수 있었다. 또한 유치의 비정상적인 치근흡수가 나타났고, 하악 전치의 경우 치근형태가 짧고, 치근단이 둥근 형태로 나타났다. 이에 저자는 가성부갑상선기능저하증인 환아의 구강내 소견에 대해 보고하고자 한다.