Restorative Dentistry and Endodontics

The Korean Academy of Conservative Dentistry (대한치과보존학회)
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Silver nanoparticles in endodontics: recent developments and applications

  • Aysenur Oncu (Department of Endodontics, Ankara University Faculty of Dentistry) ;
  • Yan Huang (Department of Dental Hygiene Research & Development in Health & Care, Artevelde University of Applied Sciences) ;
  • Gulin Amasya (Department of Pharmaceutical Technology, Ankara University Faculty of Pharmacy) ;
  • Fatma Semra Sevimay (Department of Endodontics, Ankara University Faculty of Dentistry) ;
  • Kaan Orhan (Department of Dentomaxillofacial Radiology, Ankara University Faculty of Dentistry) ;
  • Berkan Celikten (Department of Endodontics, Ankara University Faculty of Dentistry)
  • Received : 2020.10.22
  • Accepted : 2021.01.04
  • Published : 2021.08.31
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Abstract

The elimination of endodontic biofilms and the maintenance of a leak-proof canal filling are key aspects of successful root canal treatment. Several materials have been introduced to treat endodontic disease, although treatment success is limited by the features of the biomaterials used. Silver nanoparticles (AgNPs) have been increasingly considered in dental applications, especially endodontics, due to their high antimicrobial activity. For the present study, an electronic search was conducted using MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar, and EMBASE. This review provides insights into the unique characteristics of AgNPs, including their chemical, physical, and antimicrobial properties; limitations; and potential uses. Various studies involving different application methods of AgNPs were carefully examined. Based on previous clinical studies, the synthesis, means of obtaining, usage conditions, and potential cytotoxicity of AgNPs were evaluated. The findings indicate that AgNPs are effective antimicrobial agents for the elimination of endodontic biofilms.

Keywords

References

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