• 대한음성학회지:말소리
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• 제54호
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• pp.15-26
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• 2005

The aim of this paper was to analyze the lexical effects on spoken word recognition of Korean monosyllabic word. The lexical factors chosen in this paper was frequency, density and lexical familiarity of words. Result of the analysis was as follows; frequency was the significant factor to predict spoken word recognition score of monosyllabic word. The other factors were not significant. This result suggest that word frequency should be considered in speech perception test.

• 대한한방소아과학회지
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• 제19권1호
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• pp.53-66
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• 2005

Objectives : Osteoporosis is generally occurred in old age, especially postmenopausal women therefore, it is relatively overlook osteoporosis in children, but the authors have paid attention to bone density in children because maximizing peak bone mass of childhood is advocated as a way to prevent osteoporosis and environmental factor of childhood play role in the regulation of bone density. the present study was performed to measure bone density of children and to assess the influence of age, sex, body size, exercise, weak symptoms on bone density during the period of bone growth. Methods : We have measured bone density of calcaneus bone in 283 children (male 144 female 139, ranged from3 to 18) who visited in growth clinic of Pediatrics, Dongguk University Bundang Oriental Hospital, using quantitative ultra sound densitometry and they were divided into 3 groups by age(3-10, 11-15, 15-18 years). Pearson's correlation was used to assessed the influence of age, body size and Student's t-test was used to detect differences in sex, exercise, weak symptoms between the groups on bone density Results : The bone density correlated with age, height, weight, body mass index in this study. Bone density were significantly higher in males than in female. Digestive weak children's bone density were lower than normal children. Conclusion : Weight-bearing exercise and food rich in nutrition are necessary to increase maximizing peak bone mass in children.

• 한국가스학회지
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• 제19권1호
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• pp.64-70
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• 2015

TRIP강의 수소에 의한 취성화정도를 확인하기 위하여 산성과 알칼리성 전해질 분위기 하에서 전류밀도와 주입시간을 달리하여 수소를 강제주입시킨 후 sp시험으로 평가하고자 하였다. SP시험결과 산성 전해질 분위기가 알칼리성 전해질 분위기에 비해 수소 취성화가 더욱 민감하게 반응하는 것으로 조사되었다. 또한 산성 전해질은 주입시간과 전류밀도가 수소취성화에 영향을 미치는 인자로 확인되었으며, 알칼리성 전해질은 주입시간이 전류 밀도보다 수소 취성화를 촉진하는 요소로 조사되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5819-5823
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• 2014

Purpose: To investigate the expression of hypoxia-inducible factor prolyl hydroxylase 3 (HIFPH3) in non-small cell lung cancer (NSCLC) and explore the correlation of HIFPH3 expression with lymph node metastasis and microvessel density (MVD). Materials and Methods: A total of 73 cases of NSCLC specimens, 24 cases of para-cancerous tissues, and 20 normal pulmonary tissues were collected for HIFPH3 and CD31 immunohistochmical (IHC) study. Microvessel density (MVD) of the NSCLC tissues was also determined based on the expression of CD31. Results: The expression of HIFPH3 in carcinoma tissue was statistically higher than para-cancerous and normal pulmonary tissues (${\chi}^2=48.806$, p<0.05). Compared withthe negative lymph node metastasis group, the lymph node metastasis group showed significantly higher HIFPH3 expression (${\chi}^2=6.300$, p<0.05). The strong HIFPH3+group displayed a significantly higher MVD than weak HIFPH3+ and HIFPH3- groups (p<0.05). No differences in positive HIFPH3 expression were noted regarding the tumor diameter, age, smoking status, gender of NSCLC patients, tumor size, histopathology, or differentiation. Conclusions: HIFPH3 expression in human NSCLC lesions is significantly higher than that in para-cancerous and normal lung tissues and is positively associated with lymph node metastasis and MVD.

• 한국재료학회지
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• 제5권6호
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• pp.639-643
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• 1995

수소화된 비정질 게르마늄 (a-Ge : H)에 대해 전기전도율이 297-423K 사이에서 연구되었다. 측정된 전기전도율의 Arrhenius 구성에 의해 pre-exponential 인수 $\sigma$$_{0}$ 및 활성화에너지 $E_{c}$- $E_{F}$가 결정되었다. 튀어오름(kink) 온도의 존재로 인해 전기전도율의 arrhenius 구성이 두 exponential 함수에 의해 표현되었고, 이에 의해 결정된 페르미준위의 통계이동계수 ${\gamma}$$_{F}$는 약 8.65$\times$$10^{-3}$eV/K이었으며, $\sigma$$_{0}$는 약 2$\Omega$$^{-1}$$cm^{-1}$ /이었다. 전기전도율 데이터로부터 결함밀도가 수치해석적 방법에 의해 계산되었고, 결함밀도는 측정된 온도영역하에서 약 2배 정도 변화하였다 변화하였다화하였다

• 농업생명과학연구
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• 제45권1호
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• pp.15-20
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• 2011

본 연구는 전북 무주지역 36년생 리기다소나무 임분을 대상으로 지상부 바이오매스 추정식을 개발하고, 줄기밀도와 바이오매스 확장계수를 산출하고자 하였다. 리기다소나무의 흉고직경을 독립변수로 하고 바이오매스를 종속변수로 하는 상대생장식을 추정한 결과, 잎 (78%)과 가지 (83%)를 제외하면 모든 부위에서 결정계수가 95% 이상의 높은 설명력을 나타냈다. 리기다소나무의 바이오매스량은 줄기 목질부 $65.9 Mg\;ha^{-1}$, 줄기 수피 $9.5Mg\;ha^{-1}$, 가지 $19.6Mg\;ha^{-1}$, 잎 $7.0Mg\;ha^{-1}$, 전체 $102Mg\;ha^{-1}$로 나타났으며, 바이오매스 구성비는 줄기목질부 (64.6%) > 가지 (19.2%) > 줄기 수피 (9.3%) > 잎 (6.9%) 순으로 나타났다. 리기다소나무의 줄기밀도 $(g/cm^{3})$는 0.453으로 나타났고, 바이오매스 확장계수는 1.344로 나타났다.

• Journal of Ginseng Research
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• 제43권1호
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• pp.95-104
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• 2019

Background: Oxidized low-density lipoprotein (ox-LDL) causes vascular endothelial cell inflammatory response and apoptosis and plays an important role in the development and progression of atherosclerosis. Ginsenoside compound K (CK), a metabolite produced by the hydrolysis of ginsenoside Rb1, possesses strong anti-inflammatory effects. However, whether or not CK protects ox-LDL-damaged endothelial cells and the potential mechanisms have not been elucidated. Methods: In our study, cell viability was tested using a 3-(4, 5-dimethylthiazol-2yl-)-2,5-diphenyl tetrazolium bromide (MTT) assay. Expression levels of interleukin-6, monocyte chemoattractant protein-1, tumor necrosis factor-${\alpha}$, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 were determined by enzyme-linked immunosorbent assay and Western blotting. Mitochondrial membrane potential (${\Delta}{\Psi}m$) was detected using JC-1. The cell apoptotic percentage was measured by the Annexin V/ propidium iodide (PI) assay, lactate dehydrogenase, and caspase-3 expression. Apoptosis-related proteins, nuclear factor $(NF)-{\kappa}B$, and mitogen-activated protein kinases (MAPK) signaling pathways protein expression were quantified by Western blotting. Results: Our results demonstrated that CK could ameliorate ox-LDL-induced human umbilical vein endothelial cells (HUVECs) inflammation and apoptosis, $NF-{\kappa}B$ nuclear translocation, and the phosphorylation of p38 and c-Jun N-terminal kinase (JNK). Moreover, anisomycin, an activator of p38 and JNK, significantly abolished the anti-apoptotic effects of CK. Conclusion: These results demonstrate that CK prevents ox-LDL-induced HUVECs inflammation and apoptosis through inhibiting the $NF-{\kappa}B$, p38, and JNK MAPK signaling pathways. Thus, CK is a candidate drug for atherosclerosis treatment.

• Archives of Plastic Surgery
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• 제37권5호
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• pp.509-518
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• 2010

Purpose: Major drawbacks of conventional bone marrow stromal cells (BSCs) transplantation method are mainly caused by direct transplanted cell to host cell interactions. We hypothesized that separation of the transplanted cells by a microporous membrane might inhibit most of the potential adverse effects and induce superior effect. The purpose of the study is to determine the optimal condition of the microporous membrane. Methods: First, BSCs were placed in polyethylene terephthalate (PET) transwell inserts with 3, 8, or $12{\mu}m$ pore size, and cultured in 24 well culture plates. After 5 days, bottoms of the plates were observed for presence of attached BSCs in monolayer and cell numbers were evaluated. Second, BSCs were placed PET, polycarbonate (PCT), and mixed cellulose esters (MCE) transwell inserts with 3 and $8{\mu}m$ pore size, and cultured in 24 well culture plates. After 3 days, the supernatants of the media left in culture plate were analyzed for collagen, vascular endothelial growth factor (VEGF), platelet derived growth factor BB (PDGF-BB), and basic fibroblast growth factor (bFGF). Third, BSCs were placed in 15% and 70% of the PET membrane with $3{\mu}m$ pore size. All the experimental conditions and methods were same as the second study. Results: The optimal pore sizes to prevent BSC leakage were $3{\mu}m$ and $8{\mu}m$. The amounts of type I collagen and three growth factors tested did not show significant differences among PET, PCT, and MCE groups. However, the collagen, VEGF, and bFGF levels were much higher in the high (70%) density group than in the low (15%) density group. Conclusion: This study revealed that the optimal pore size of membrane to prevent direct BSC to recipient cell contact is in between $3{\mu}m$ and $8{\mu}m$. Membrane materials and pore sizes do not influence the collagen and growth factor passage through the membrane. The most striking factor for collagen and growth factor transport is pore density of the membrane.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2006년도 추계학술대회 논문집 Vol.19
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• pp.219-220
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• 2006

In this study, m order to develop multilayer ceramics vibrator for ultrasonic nozzle, PMN-PNN-PZT ceramics were fabricated using $Li_2CO_3-Na_2CO_3$ as sintering aids and their piezoelectric and dielectric characteristics were investigated according to the aomunt of PbO. With increasing PbO contents. secondary phases were increased and phase structure were changed from tetragonal structure to rhombohedral structure and also electromechanical coupling factor were linearly decreased. At the composition ceramics with the sintering temperature of $870^{\circ}C$ and 1 mol% excess PbO, density, electromechanical coupling factor, dielectric constant, piezoelectric d constant and mechanical quality factor showed the optimum value of $7.879g/cm^2$, 0.55, 1149, 328pC/N, 1224, respectively for multilayer ceramics vibrator application for ultrasonic nozzle.

• 천문학회보
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• 제37권1호
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• pp.85.1-85.1
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• 2012

In this study we use three-dimensional magnetohydrodynamic simulations of flux emergence from solar subsurface layer to corona. In order to study the twist parameter of magnetic field we compare the simulations for strongly twisted and weakly twisted cases. Based on the results, we derive a flux expansion factor of selected flux tubes which is a ratio of expanded cross section to the one measured at the footpoint of the flux tube. To understand the effect of flux expansion factor, we make a comparison between magnetic field configuration and the expansion factor. By using a fitting function of hyperbolic tangent we derive noticeable correlations among the strength of the vertical magnetic field, current density and expansion factor. We discuss what these results tell about the relationship between the twist of emerging field and the mechanism for the solar wind.