• 한국융합학회논문지
• /
• 제9권8호
• /
• pp.379-392
• /
• 2018

본 연구는 치매노인보호자의 부양부담이 대인관계문제에 미치는 영향에서 가족지지의 조절효과를 검증하고, 이를 바탕으로 사회복지적 함의를 제시하는 것을 목적으로 한다. 이를 위해 수도권 7곳, 지방 11곳에 위치한 주간보호센터 및 치매지원센터를 이용하는 치매노인의 보호자 중 자녀 및 며느리 341명을 대상으로 자기보고식 설문조사를 실시하였고, 본 연구에서는 불성실한 응답을 제외한 326명을 최종 분석에 사용하였다. 연구의 가설을 검증하기 위하여 빈도분석, 기술통계 분석과 다중회귀분석을 사용하였다. 분석 결과, 치매노인보호자의 50.9%가 높은 부양부담을 경험하고 있으며, 43.6%가 고위험의 대인관계문제를 가지고 있는 것으로 나타났다. 회귀분석을 실시한 결과, 부양부담은 대인관계문제에 정적인 영향관계를 가지는 것으로 검증되었다. 또한, 가족지지는 부양부담과 대인관계문제간의 관계를 조절하는 것으로 확인되었다. 이들 바탕으로 하여 부양부담으로 인해 대인관계문제를 겪고 있는 치매노인보호자들을 위한 가족 및 대인관계 개선 프로그램 도입 등의 실천적, 정책적 개입 방안을 제언하였다.

• 정신신체의학
• /
• 제21권2호
• /
• pp.140-146
• /
• 2013

연구목적 본 연구는 치매 군과 비치매 군의 통증 역치 및 통증 경험의 특성을 비교 하고자 한다. 방 법 2010년 강원 조기치매 검진사업의 일환으로 시행된 것으로, 연구 대상은 지역사회 거주중인 65세 이상 노인 8,302명이었다. 이 중, 한국판 간이정신상태검사(MMSE-KC) 점수가 저하 된 1259명을 선별했고, 이중 365명이 한국형 치매 진단평가 도구(CERAD-K)를 이용한 정밀검진을 받았다. 검사 결과 및 전문의의 판단 하에 정상, 경도인지장애, 치매 군으로 진단 후, 최종 비치매 군 90명, 치매 군 57명이(경도-중등도 알츠하이머형 치매) 분석되었다. 압통각계(Pressure algometer)를 이용하여 실험적으로 통증 역치를 측정했고, 자가보고식 검사인 Brief pain inventory(BPI)를 이용하여 통증 경험(통증 심도, 통증 방해도)을 조사했다. 집단 간 차이 분석은 Pearson Chi-Square와, 혼란변인(성별, 나이, 교육수준, GDS, 당뇨)을 보정한 ANCOVA검정을 시행했다. 결 과 인구학적 특성상 치매 환자 군에서 여성이 많고, 연령이 높고, 교육 연수가 낮았다. 통증 역치는 두 군에서 통계적으로 의미 있는 차이가 발견되지 않았다. BPI결과에서 비치매 군이 어깨 통증, 전체 통증 개수, '통상적 일'의 통증으로 인한 방해를 의미 있게 더 많이 호소했다(p<0.05). 그러나 두 군에서 통증 유병률 및 치료는 차이가 없었다. 결 론 치매 군은 비치매 군보다 통증을 더 적게 경험했다. 이는 치매 환자의 통증 역치는 보존되었으나, 내성이 증가한다는 선행 연구를 뒷받침 하는 증거로 여겨진다. 따라서, 치매 환자를 위한 적극적인 통증 사정 및 치료를 제안한다.

• 성인간호학회지
• /
• 제23권1호
• /
• pp.40-49
• /
• 2011

Purpose: This study aimed to identify the prevalence of mild cognitive impairment (MCI) among a group of community-dwelling elderly and to determine if there were differences in general characteristics, activities of daily living (ADL), perceived health status (PHS) between the MCI group and group of elderly with normal cognitive function. Methods: This study utilized a descriptive survey design. Six hundred and five subjects over the age 65 were recruited from an S public health center, Seoul. Data were gathered through a variety of instruments: MoCA-K, K-MMSE, K-MBI, S-IADL, and PHS scale. Data were analyzed by SPSS/WIN 18.0 using descriptive statistics, Chi-Square test and t-test. Results: The prevalence of MCI among the subjects was 46.0%. Differences in IADL, PHS, age, education, sex, and residing with a spouse were statistically significant between groups. The MCI group had lower IADL, lower PHS, were older, and had lower educational levels than the group with normal cognitive function. Further, the MCI group was less likely to live with a spouse. Conclusion: It is suggested that MCI group should be targeted in developing and implementing nursing strategies to prevent dementia and improve the elderly cognitive function.

• Journal of Medicine and Life Science
• /
• 제17권3호
• /
• pp.65-73
• /
• 2020

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a single-gene disease of the cerebral small blood vessels caused by mutations in the NOTCH3 gene on chromosome 19. Although CADASIL was known as a rare disease, recent research has suggested that the NOTCH variants could be found frequently even in the general population. The main clinical features included recurrent stroke, migraine, psychiatric symptoms, and progressive cognitive decline. On brain magnetic resonance imaging, patients with CADASIL showed multifocal white matter hyperintensity lesions, lacunar infarcts, microbleeds, and brain atrophy. Among them, lacunar infarcts and brain atrophy are important in predicting the clinical outcomes of patients with CADASIL. In the Jeju National University Hospital, we have diagnosed 213 CADASIL patients from 2004 to 2020. Most NOTCH3 mutations were located in exon 11 (94.4%), and p.Arg544Cys was the most common mutation. The mean age at diagnosis was 61.0±12.8 years. The most common presenting symptoms were ischemic stroke (24.4%), followed by cognitive impairment(15.0%), headache (8.9%), and dizziness(8.0%). Although the exact prevalence of CADASIL in Jeju is still unknown, the disease prevalence could be as high as 1% of the population considering the prevalence reported in Taiwan. Therefore, it is necessary to discover efficient biomarkers and genetic tests that can accurately screen and diagnose patients suspected of having CADASIL in this region. Ultimately, it is urgent to explore the exact pathogenesis of the disease to identify leading substances of treatment potential, and for this, multi-disciplinary research through active support from the Jeju provincial government as well as the national government is essential.

• 수면정신생리
• /
• 제14권1호
• /
• pp.5-12
• /
• 2007

Sleep changes substantially with age. There is a phase advance in the circadian sleep cycle and increased waking after sleep onset. The elderly people wake more frequently during the night and experience fragmented sleep and excessive daytime sleepiness. The prevalence of sleep disorders increases with age, and the composition of sleep disorders in the elderly differs from that in the young. The most frequently encountered sleep disorders are psychophysiologic insomnia, sleep disturbance due to dementia, sleeprelated respiratory disorder, restless legs syndrome and periodic limb movement disorder, and REM sleep behavior disorder. To treat the elderly sleep problem appropriately, it is important to know how sleep pattern changes as we age and to understand the cause of sleep-related symptoms. This article will review the sleep physiology and common sleep disorders in the elderly.

• 대한예방의학회:학술대회논문집
• /
• 대한예방의학회 1998년도 제50차 추계 학술대회 연제집
• /
• pp.175-176
• /
• 1998

• Journal of Korean Medical Science
• /
• 제33권47호
• /
• pp.300.1-300.17
• /
• 2018

Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although its major manifestation is motor symptoms, resulting from the loss of dopaminergic neurons in the substantia nigra, psychiatric symptoms, such as depression, anxiety, hallucination, delusion, apathy and anhedonia, impulsive and compulsive behaviors, and cognitive dysfunction, may also manifest in most patients with PD. Given that the quality of life - and the need for institutionalization - is so highly dependent on the psychiatric well-being of patients with PD, psychiatric symptoms are of high clinical significance. We reviewed the prevalence, risk factors, pathophysiology, and treatment of psychiatric symptoms to get a better understanding of PD for improved management.

• The Journal of Korean Physical Therapy
• /
• 제20권4호
• /
• pp.61-69
• /
• 2008

Purpose: We evaluated caregivers' understanding of patients' diseases and disuse syndrome, the understanding of exercise and massage related to rehabilitation and the necessity of education about these, the difference in education and realities of the care-giving field, and the extra services needed in the field. Methods: The survey using questionnaires was performed from June 2008 to August 2008 with 220 people participated in caregive education programme in daegu city and area near dagu city. Among the 220 submitted questionnaires, 184 which were faithfully answered were selected and they were analyzed by i-STATistics statistical program. Results: The educational focus of the first and second level caregivers, as defined by the second clause of the 29th article of the Elderly Welfare law, is on basic knowledge of diseases such as dementia, stroke, and depression. However, other diseases are not covered and the information does not include information on decreased function, complications, functional rehabilitating exercises, or preventing disuse syndrome for long term patients. The most common diseases, in order of prevalence, are stroke, dementia, diabetes mellitus, Parkinson disease, arthritis, and geriatric inertness. The general level of awareness about disuse syndrome was low, and patients, while understanding the need for massage and rehabilitative exercise, receive little education about the proper methods and therefore cannot use them. Patients also did not understand how participating in these activities could reduce medical fees, indicating that further education on massage and rehabilitative exercise is needed. Caregivers desired to include positive rehabilitation, massage, and exercise-related services in their services. Finally, differences in caregiver education and reality resulted from a lack of diversity in education. Conclusion: We suggest providing education on disuse atrophy and improving the lack of diversity in the care-giving education system.

• 대한치매학회지
• /
• 제17권4호
• /
• pp.156-162
• /
• 2018

Background and Purpose: Previous studies have reported conflicting results about the prevalence of seizures in Alzheimer's disease (AD). There are few epidemiological studies on this topic in Asia. Thus, the objective of this study was to examine demographic and clinical characteristics as well as incidence for seizures in AD patients compared to non-AD patients in a prospective, longitudinal, community-based cohort with a long follow-up. Methods: Data were collected from National Health Insurance Service-National Elderly Cohort (NHIS-elderly) Database to define patients with AD from 2004-2006 using Korean Classification Diseases codes G30 and F00. We performed a 1:5 case-control propensity score matching based on age, sex, and household income. We conducted Cox proportional hazards regression analysis to estimate the risk of epilepsy in AD patients. Results: In the cohort study, patients with AD had higher risk for epilepsy than those without AD, with hazard ratio of 2.773 (95% confidence interval [CI], 2.515-3.057). This study also showed that male gender and comorbidities such as hypertension, hyperlipidemia, diabetes, and chronic kidney disease increased the risk of developing epilepsy. Patients with AD had 1.527 (95% CI, 1.375-1.695) times higher mortality rate than those in the control group. Conclusions: AD patients have significantly higher risk of developing epilepsy than non-AD patients.

• 융합정보논문지
• /
• 제9권8호
• /
• pp.248-253
• /
• 2019

노인성 치매의 전 임상단계인 경도인지장애(MCI)를 조기 진단하고, 조기 개입한다면, 치매의 발병률을 줄일 수 있다. 본 연구는 우리나라 지역사회 노인의 MCI 예측 모형을 개발하고 노년기 인지장애의 예방을 위한 기초자료를 제공하였다. 연구대상은 2012년 Korean Longitudinal Survey of Aging(KLoSA)에 참여한 65세 이상 지역사회 노인 3,240명(남성 1,502명, 여성 1,738명)이다. 결과변수는 MCI유병으로 정의하였고, 설명변수는 성, 연령, 혼인상태, 교육수준, 소득수준, 흡연, 음주, 주1회 이상의 정기적인 운동, 월평균 사회활동 참여시간, 주관적 건강, 고혈압, 당뇨병을 포함하였다. 예측모형의 개발은 Restricted Boltzmann Machine(RBM) 인공신경망을 이용하였다. RMB 인공신경망을 이용하여 우리나라 지역사회 노인의 MCI 예측 모형을 구축한 결과, 유의미한 요인은 연령, 성별, 최종학력, 주관적 건강, 혼인상태, 소득수준, 흡연, 규칙적 운동이었다. 이 결과를 기초로 MCI 고위험군의 특성을 고려한 맞춤형 치매 예방 프로그램의 개발이 요구된다.