• 치위생과학회지
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• 제9권1호
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• pp.53-59
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• 2009

치과위생사의 감염관리 실천도를 측정하는 척도를 개발하고 타당화하기 위해 254명의 치과위생사를 대상으로 설문조사를 실시하였다. 예비척도는 리커트 4점 척도로서 21개의 문항으로 구성되었으며, 신뢰도 분석, 탐색요인분석, 확인요인분석을 통해 척도의 차원과 항목을 축소하고 신뢰도와 타당도를 검증하였다. 1. 탐색요인분석과 신뢰도 분석을 통해 4개 요인과 12개의 항목으로 척도를 수정하였다. 수정된 척도의 요인은 '예방접종 및 정기검진'(2항목), '기구 소독 및 멸균'(3항목), '손위생 관리'(4항목), '개인 보호'(3항목)가 추출되었으며, 전체분산 중 58.296%를 설명하고 있다. 예비척도 중 '환경 관리' 요인이 제외되었다. 2. 확인요인분석을 통해 한 문항을 제외하였다. 최종적인 측정모형은 4개 요인과 11개 항목으로 구성되었으며, 모형의 적합도는 $x^2$= 79.593(df = 38, 0 = 0.000), RMR= 0.045, GFI = 0.940, CFI = 0.904, AGFI = 0.896, NFI = 0.837, TLI = 0.861, RMSEA = 0.67로 나타나 대체로 기준을 충족하였다. 모든 측정변수의 요인부하량은 유의하였으나(p < 0.001), 세 변수만이 0.7 이상으로 나타났다. 평균분산추출값과 구성개념신뢰도는 대체로 기준을 충족하지 못하였으나, 모든 요인의 평균분산추출값은 각 요인간 상관관계제곱값 보다 크게 나타났다. 3. 요인분석을 통해 추출한 네 개의 요인이 치과위생사의 '감염관리 실천률 인식'에 미치는 영향을 알아보기 위해 네 요인을 독립변수로 선정하고 실천률 인식을 종속변수로 선정하여 회귀분석을 실시하였다. $R^2$는 0.304, 수정된 $R^2$은 0.431, F = 25.813, p = 0.000이며, '손위생 관리'를 제외한 세 변수의 회귀계수는 통계적으로 유의하게 나타났다.

• 한국사회복지학
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• 제63권2호
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• pp.319-336
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• 2011

본 연구는 외국인 며느리를 둔 시부모를 대상으로 하여 문화적응 스트레스를 측정하기 위한 척도를 개발하고 그 신뢰도와 타당도를 검증해보고자 하였다. 이를 위하여 기존의 유학생을 대상으로 하는 문화적응 스트레스 척도를 기본척도로 하여 다문화 가정의 시부모에 적합하도록 재구성하였다. 분석 결과, 문항의 제거와 표본의 이상치 점검을 위한 문항분석을 통하여 최종적으로 11문항이 선정되었다. 다음으로 문화적응 스트레스 척도의 요인구성을 살펴보기 위하여 탐색적 요인분석을 실시하였으며 시부모의 문화적응 스트레스 척도는 '편견 및 차별감 지각', '문화적 가치관 차이로 인한 갈등', '일상생활의 불편'의 세 가지 요인으로 구성됨을 확인하였다. 이렇게 구성된 척도의 타당도를 검증하기 위하여 구조모형을 통한 확인적 요인분석을 실시하였으며 그 결과 양호한 모형적합도를 보여주었다. 척도의 신뢰도는 Cronbach's ${\alpha}$로 검증하였으며 0.86으로 나타났다.

• Journal of Genetic Medicine
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• 제2권2호
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• pp.53-57
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• 1998

Spinal muscular atrophy (SMA) type I is a common severe autosomal recessive inherited neuromuscular disorder that has been mapped to chromosome 5q11.2-13.3. The survival motor neuron (SMN) gene, a candidate gene, is known to be deleted in 96% of patients with SMA type I. Presently, PCR and single strand conformation polymorphism (PCR-SSCP) analyses have been made possible for application to both archival slides and paraffin-embedded tissues. Archival materials represent valuable DNA resources for genetic diagnosis. We applied these methods for the identification of SMN gene of SMA type I in archival specimens for the prenatal diagnosis. In this study, we performed the prenatal diagnosis with chorionic villus sampling (CVS) cells on two women who had experienced neonatal death of SMA type I. DNA extraction was done from archival slide and tissue materials and PEP-PCR was performed using CVS cells. In order to identify common deletion region of SMN and neuronal apoptosis-inhibitory protein (NAIP) genes, cold PCR-SSCP and PCR-restriction site assay were carried out. Case 1 had deletions of the exons 7 and 8, and case 2 had exon 7 only on the telomeric SMN gene. Both cases were found to be normal on NAIP gene. These results were the same for both CVS and archival biopsied specimens. In both cases, the fetuses were, therefore, predicted to be at very high risk of being affected and the pregnancy were terminated. These data clearly demonstrate that archival slide and paraffin-embedded tissues can be a valuable source of DNA when the prenatal genetic diagnosis is needed in case any source for genetic analysis is not readily available due to previous death of the fetus or neonate.

• 한국방사선학회논문지
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• 제14권6호
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• pp.801-810
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• 2020

본 연구에서는 PET 검사의 건강보험 적용 및 급여기준 변경 현황을 살펴보고, 지난 10년간 건강보험 이용량을 분석하였다. PET 검사가 건강보험으로 적용된 것은 2006년으로 ¹⁸F-FDG가 최초로 건강보험으로 적용된 이후 여러 가지 방사성동위원소를 이용한 PET 검사가 건강보험으로 적용되고 있다. 2019년 기준 PET 검사 수는 198,651건, 진료금액은 약 883억원이며, 일반적 특성에 따른 검사 수는 남성이 여성보다 많았고, 연령별로는 60대에서 검사수가 가장 많았다. 외래 검사수가 입원 검사수 보다 많았고, 상급종합병원 검사수가 68.2%로 종합병원, 병원보다 월등히 많았다. 검사부위는 토르소 검사가 86.6%로 가장 많았으며, 방사성동위원소는 ¹⁸F-FDG를 이용한 검사수가 93.6%로 가장 많았다. 10년간 건강보험 이용량 변화로는 2010년 부터 2014년까지 꾸준히 증가하였으나 2014년 정부의 건강보험 적용기준 변경에 따라 무증상 장기추적 검사의 인정이 삭제되면서 이용량이 이후 급격히 감소하였다. 정부의 건강보험 적용기준 변경이 건강보험 이용량 변화에 큰 영향을 주는 만큼 향후 지속적인 모니터링이 필요할 것이다.

• 시큐리티연구
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• 제31호
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• pp.25-45
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• 2012

시큐리티 요원이 인지하는 자신의 역할에 대한 불확실성이 시큐리티 산업의 경영성과에 직접적인 영향을 미친다는 선행연구 결과를 토대로 시큐리티 요원이 가지는 권한의 정도를 선행적으로 규명할 필요가 있다. 그러나 이를 측정할 수 있는 심리적 임파워먼트 척도에 대한 적합성이 현재까지 시큐리티 요원을 대상으로 규명되지 않았기 때문에 정보의 타당성이 불분명하다고 볼 수 있다. 따라서 본 연구에서는 시큐리티 요원의 심리적 임파워먼트 척도를 문항의 적합성, 문항의 신뢰도, 문항의 난이도, 웅답반응 범주의 적절성 관점에서의 문항 적합도를 규명하였으며 다음과 같이 요약할 수 있다. 첫째, 심리적 임파워먼트 척도의 자기결정론 요인에서 문항 11번(내 업무수행 방식에 있어서 나 스스로 결정할 수 있다)은 적합하지 않은 문항으로 나타나 향후 시큐리티 요원을 대상으로 심리적 임파워먼트를 규명할 시에는 문항 11번을 삭제하는 것이 타당하다. 둘째, 심리적 임파워먼트 척도의 문항신뢰도가 높아 다른 시큐리티 요원을 대상으로 자료를 수집하여도 결과의 일관성을 보인다. 셋째, 문항 12번(업무수행하는데 있어 독립적이며 간섭없이 일할 기회가 많다)을 응답하는데 어렵게 느끼는 반면 문항 1번(부서에 대한 나의 영향력은 크다)이 가장 쉽게 인지하고 있으며, 심리적 임파워먼트 척도의 문항난이도는 골고루 분포되어 있다. 넷째, 심리적 임파워먼트 척도의 5점 반응범주는 시큐리티 요원에게 적합한 것으로 규명되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.6007-6012
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• 2013

ANXA2, a member of the annexin family, is overexpressed and plays important roles in tumor development. However, the significance of ANXA2 expression in gastric carcinoma has not been clarified.To elucidate its roles in growth of gastric cancer, ANXA2 expression in SGC-7901 cells was inhibited with a designated siRNA, then cell proliferation, cell cycling, apoptosis and motility were determined by MTT assay, flow cytometry, Hoechst 33342 staining and wound healing assay, respectively. To further assess the behavior of ANXA2 deleted SGC-7901 cells, changes of microstructures were observed under fluorescence microscopy, laser scanning confocal microscopy and electron microscopy. We found that inhibition of ANXA2 expression caused cell proliferation to decrease significantly with G1 arrest, motility to be reduced with changes in pseudopodia/filopodia structure and F-actin and ${\beta}$-tubulin expression, and apoptosis to be enhanced albeit without significance. At the same time, ANXA2 deletion resulted in fewer pseudopodia/filopodia, non-stained areas were increased, contact inhibition among cells reappeared, and expression of F-actin and ${\beta}$-tubulin was decreased, with induction of polymerized disassembled forms. Taken together, these data suggest that ANXA2 overexpression is important to maintain the malignancy of cancer cells, and this member of the annexin family has potential to be considered as a target for the gene therapy of gastric carcinoma.

• 대한간호학회지
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• 제29권6호
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• pp.1365-1378
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• 1999

This study is a methodological research study to develop an instrument to measure in patients with cancer and to test the validity and reliability of the instrument. The research procedure was as follows : 1) The first step was to develop conceptual framework based on a comprehensive review of the literature and in-depth interviews with patients with cancer. This conceptual framework was organized in to three dimensions (the intrapersonal dimension, the significant-other and context related dimension, the transcendental dimension). Initially 59 items were adopted. 2) These items were analyzed through the index of content validity(CVI) and 53 items were selected which met more than 80% on the CVI. 3) The pretest was carried out with 87 patients with cancer. After the pretest results were analyzed by item analysis, 44 items were selected. A second test of content validity was conducted and 6 items were eliminated considering the 80% CVI. 4) To test for reliability and validity, data collection was done during the period from January 25, 1999, to February 26, 1999. The subjects for the test were 160 patients with cancer and 185 healthy persons. analysis, item analysis and multitrait-multimethod method to analyze validity. The findings are as follows : 1) The Cronbach's alpha coefficient for internal consistency was .92 for the total 38 items and .79, .82, .85, for the three dimensions in that order. 2) The item analysis was based on the corrected item to total correlation coefficient( .30 or more) and information about the alpha estimate if this item was dropped from the scale. 3) As a result of the initial factor analysis using principal component analysis and varimax rotation, one item was deleted because of factor complexity (indiscriminate factor loadings). In the secondary factor analysis, 7 factors with eigenvalue of more than 1.0 were extracted and these factors explained 56 percents of the total variance. The seven factors were labeled as 'family relationship', 'emotional condition', 'physical discomfort', 'meaning and goal of life', 'contextual stimuli', 'change of body image', 'guilt feelings'. 4) The convergence effect between this instrument and the life satisfaction scale was identified and there was significant positive correlation(r= .52, p= .00). The discriminant validity between this instrument and the depression scale(CES-D) was tested and there was significant negative correlation(r= -.50, p= .00). The instrument for accessing the suffering of patients with cancer developed in this study was identified as a tool with a high degree of reliability and validity. In this sense, this tool can be effectively utilized for assessment in caring for patients with cancer.

• 한국조경학회지
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• 제18권3호통권39호
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• pp.99-113
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• 1990

The purpose of this study was to prepare some more up-dated and advanced curriculum in Landscape Architecture in Junior College education to bring up a leading professional who can meet the changing social needs. To achieve this goal, the data about the actual employment status of graduates, current relevant systems and legistations, the questionnaires of Landscape companies, graduates and undergraduates, and the current relevant curriculum of domain 6 junior colleges and Japanese relevant curriculum was gathered and analyzed The results are as follows ; 1. Currently the majority of the graduates are employed in Construction field, but the employment trend of graduates shows diversification and subdividing as following 5 fields, that is Construction, Design, Maintenance, Administration and Indoor Landscaping. 2. It is essential to bring up a Landscape Technician who has a Landscape Certificate of qualifications(esp. 2nd class). 3. Lately, the actual Practice came to be one item of the qualifying examination, so the subjects of Landscape Design, Landscape Construction and Landscape Estimation Should be emphasized, Accordingly, current curriculum should be revised. 4. Currant curriculum model(1979) made by the Ministry of Education doesn't play a real and adequate role and should be up-dated in view of the current curriculum of domain 6 junior colleges has no regular standards. In preparation for new standardized curriculum model, following criterior could be suggested, that is, ratio of the Major Required Subjects vs. The Major Optional Subjects would be 50 : 50, and the Major Optional Subject would be 48 credits which is 150% of the Required Credits(32 credits) 5. The subjects such as Basic Agriculture, Afforestation, Nature Conservation, Sketch, Civil Engineering, Landscape Seminar and Modelling Practice would be deleted in the curriculum model established in 1983. 6. The subjects such as Perspective Practice, Indoor Landscaping, Landscape Legislation and Landscape Design( III ) could be newly opened to meet the social needs, to prepare for the qualifying examination and to serve well in the employment fields. 7. The subjects of Surveying ( I ) & ( II ) would be unified into one Subject as Surveying, and some in view of the average situation of 6 junior colleges. 8. It is urgent to open some subject related to computer. At first, An Introduction to Computer could be recommended in the cultural studies course and Landscape Computer Technique as the Major Optional Subjects.

• 한국수자원학회논문집
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• 제51권1호
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• pp.81-88
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• 2018

도시지역의 모든 하수관망을 사용하여 구축된 강우-유출모형은 그 규모가 방대하고 복잡하여 실시간 도시홍수예보에 적합하지 않다. 따라서 본 연구에서는 상대적으로 도시화가 많이 진행된 서울시의 상습침수지역인 도림천 대림배수분구의 하수관망도를 이용하여 강우-유출모형을 구축하고 이를 단순화하였다. 하수관망 단순화는 노드의 누가유역면적을 단순화의 범위 산정을 위한 기준으로 설정하고 총 5단계의 과정으로 나누었으며 단순화 과정에서 SWMM의 모든 매개변수들을 면적가중치를 적용하여 계산하였다. 또한 하수관망의 적정 단순화 범위를 산정하기 위하여 유출모형에 5가지 단순화 범위를 설정하고 유출분석과 침수분석을 실시하였다. 그 결과, 유출모형의 노드와 관망의 개수 그리고 모의시간 모두 단순화 범위에 따라 50~90%까지 일정하게 감소하였으며 단순화 이전과 동일한 유출량 결과를 나타내었다. 2차원 침수분석의 경우, 누가유역면적별로 단순화의 범위가 커질수록 월류지점의 개수가 크게 감소하고 위치가 바뀌었으나 비슷한 침수양상을 나타내었다. 다만 누가유역면적을 기준으로 6 ha 이상에서는 상류부터 삭제되는 노드에 의해 나타내지 못하는 침수지역이 발생하였다. 2차원 침수면적, 주요침수구간, 침수심 등을 비교 분석한 결과, 누가유역면적을 기준으로 1 ha의 단순화 범위가 단순화 이전의 분석결과와 가장 유사함을 나타내었다. 본 연구는 SWMM 매개변수를 모두 고려한 하수관망 단순화를 실시함으로써 실시간 도시홍수예보를 위한 신속하고 정확한 유출자료 생성에 활용될 수 있을 것으로 기대한다.

• 한국인구학
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• 제9권2호
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• pp.13-29
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• 1986

This study was carried out to calculate working life expectancy and its potential gains according to the degree of reduction in the specific causes of death. It sought to ascertain what potential gains in labor force longevity might be reasonably achieved through efforts to reduce mortality from injuries and poisoning, diseases of circulatory system, neoplasms and the other causes of death. The data were drawn from the three sources such as "The 1982 Causes of Death Statistics," "Abridged Life Table for Korea 1978~'79" and "The 1982 annual Report of Economically Active Population" issued by Economic Planning Board. Analytical tools used in this study were the cause-deleted life table and the Wolfbein Wool's working life table method. Partial life expectancy was adopted as an index of this study, This application will be widely used as a good demographic tool for analyzing the dynamics of labor force and causes of death. Some of the findings are summerized as follows. 1. Partial life expectancies from initial age 15, 25, and 45 respectively to terminal age 65 are 44.86, 35.59 and 17.41 year in life expectancy itself, 37.08, 32.83 and 15.21 year in working life expectancy, 7.78, 2.76 and 2.20 years in inactive life years. 2. Potential gains in working expectancy from initial age 15, 25 and 45 to terminal age 65 by the complete elimination of the specific causes of death are 1.36, 0.94 and 0.27 years in injuries and poisoning, 0.88, 0.83 and 0.54 years in diseases of circulatory system, 0.56, 0.54 and 0.37 years in neoplasms, 1.13, 1.02 and 0.58 years in the other causes of death. The relationship between degree of reduction in causes of death and potential gains in working life years is in direct proportion. The prime orders of reduction effectiveness in age groups by the causes of death are injuries and poisoning in age 15-24, the other causes of death in age 25-49 and diseases of circulatory system in age 50 and over. 3. If it were possible to reduce 25%, 50% and 75% in mortality condition 1978~'79, the average length of working life would be 38.08, 39.13 and 40.17 years in age 15, and 33.68, 34.57 and 35.44 years in age 25, and 15.67, 16.14 and 16.63 years in age 45.