• Journal of Korean Medicine Rehabilitation
• /
• v.23 no.4
• /
• pp.9-21
• /
• 2013

Objectives The purpose of this study was investigating effects of Jengjengamiyijin-tang (zhengzhuanjiaweierchentang) (JGYT) on lowering lipid, antioxidation and production of inflammatory mediators being used rats fed on high oxidized fat. Methods We divided fat Sprague-Dawley rats fed on high oxidized into 4 groups. Each of 8 rats was divided into a control group and experimental groups. We fed a control group of rats a basal diet and administered normal saline (100 mg/kg, 1 time/1 day) for 4 weeks. And We fed each experimental group of rats basal diet and administered an extract of JGYT extracts (100 mg/kg, 200 mg/kg, 300 mg/kg, 1 time/1 day) for 4 weeks. At the end of the experiment, the rats were sacrificed to determine their chemical composition. We measured lipid of plasma and liver, concentration of proinflammatory cytokines, antioxidative activity and plasma tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), plasma interleukin-6 (IL-6), Apo-B, Apo-E and Leptin gene expression. Results 1. Concentration of plasma FFA, LDL-cholesterol, plasma and liver total cholesterol showed a significant decrement in JGYT groups. However, concentration of plasma HDL-cholesterol showed a significant increment in JGYT groups. 2. Concentration of plasma and liver TG, TBARS showed a significant decrement in JGYT groups. However, concentration of liver GSH-Px, SOD and CAT showed a significant increment in JGYT groups. 3. Plasma GPT activity and concentration of plasma IL-6, TNF-${\alpha}$, NO, Ceruloplasmin, ${\alpha}1$-acid glycoprotein showed a significant decrement in JGYT groups. 4. In the analysis of RT-PCR, gene expression of Apo-B and Apo-E in the JGYT groups showed a low expression than that of control group. However, the gene expression of leptin showed no difference in all the treatment groups. 5. The ratio of leptin expression per ${\beta}$-actin expression showed no significant difference among all treatment groups. However, The ratio of Apo-B and Apo-E expression per ${\beta}$-actin expression showed a significant decrement in JGYT groups. Conclusions According to this study, extract of JGYT showed a positive effect in lowering lipid, antioxidation and control of inflammatory mediators production.

• Transactions of the Korean Society of Mechanical Engineers
• /
• v.13 no.1
• /
• pp.20-28
• /
• 1989

SEA(Statistical Energy Analysis) method has been applied to predict the sound radiation power from vibrating machinery. In this study, sound radiation power was predicted from coupled structures by transmission of vibration, which composed of two plates welded into an L shape. The predicted sound radiation power is in agreement within 2 or 3 dB on octave band comparing with values obtained from direct measurements. Also, in order to prove the validity of this method in changes of sound radiation power associated with modifications to structures, rubber pad was stuck on a plate. The results agree approximately within 3 or 5 dB. And SEA method is valuable for the optimal design to reduce the noise. Additionally, this paper suggests that the logarithmic decrement method is valid as the one for finding the loss factor.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.35 no.11
• /
• pp.1415-1422
• /
• 2011

Sheet aluminum alloys used in manufacturing of machine structures for transportation show the difference of crack growth speed depending on thickness under the constant fatigue stress condition. The referred thickness effect is a major fatigue failure property of sheet aluminum alloys. In this work, we identified the thickness effect in fatigue test of thick plate and thin plate of Al 2024-T3 alloy under the constant fatigue stress condition, and presented the thickness effect to a correlative equation, $U_{i}^{equ}=f(R_t)$ which is determined by the shape factor, thickness ratio, $R_t$ and the loading factor, equivalent effective stress intensity ratio depending on thickness, $U_{i}^{equ}$. And we analyzed quantitatively the crack growth retardation behavior in thin plate compared to thick plate by the thickness effect using ${\Delta}K$ conversion method. We obtained such values as decrement of thickness(DoT), decrement of stress intensity factor range, ${\Delta}K$ (DoS) and identified the relation between them to present the nature of thickness effect in this work.

• Transactions of the Korean Society for Noise and Vibration Engineering
• /
• v.16 no.2 s.107
• /
• pp.163-168
• /
• 2006

The PWR Nuclear Fuel assembly consists of more than 250 fuel rods that are supported by leaf springs in the cells of more than 10 Spacer Grids (SG) along the rod length. Since it is not easy to conduct mechanical tests on a full-scale model basis, the small-scaled rod bundle $(5\times5)$ which is called partial fuel assembly is generally used for various performance tests during the development stage. As one of the small-scaled tests, a flow test should be carried out in order to verify the performance of the spacer grid to obtain the Flow-Induced Vibration (FIV) characteristics of the scaled fuel assembly over the specified flow range. A vibration test should be also performed to obtain the modal parameters of the assembly prior to the flow test. In this study, we want to develop the estimation procedure of the damping ratio for the scaled test assembly. For the damping factor of the partial fuel assembly and the grid cage at the first vibration mode, as one of the vibration tests, a so-called pluck testing has been performed in air as a preliminary test prior to in-flow damping measurement test. Logarithmic decrement method is used for calculation of the damping ratio. Estimated damping ratio of the partial fuel assembly is about $0.7\%$ with reasonable error of $2\%$ for the previous results. Nonlinear behavior of the partial fuel assembly might be stem mainly from the rod-grid support configuration.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2005.11a
• /
• pp.503-506
• /
• 2005

The PWR Nuclear Fuel assembly consists of more than 250 fuel rods that are supported by leaf springs in the cells of more than 10 Spacer Grids (SG) along the rod length. Since it is not easy to conduct mechanical tests on a full-scale model basis, the small-scaled rod bundle (5$\times$5) is generally used for various performance tests during the development stage. As one of the small-scaled tests, a flow test should be carried out in order to verify the performance of the spacer grid like the coolant mixing performance and to obtain the Flow-Induced Vibration (FIV) characteristics of the rod bundle over the specified flow range. A vibration test should be also performed to obtain the modal parameters of the bundle prior to the flow test. In this study, we want to develop the estimation procedure of the damping ratio for the small scaled test bundle. For the damping factor of the rod bundle and the grid case at the first vibration mode, as one of the vibration tests, a so-called pluck testing has been performed in air as a preliminary test prior to in-flow damping measurement test. Logarithmic decrement method is used for calculation of the damping ratio. Estimated damping ratio of the rod bundle is about 0.7% with reasonable error of 2% for the previous results. Nonlinear behavior of the rod bundle might be stem mainly Iron the rod-grid support configuration.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.16 no.5
• /
• pp.33-40
• /
• 2012

To reduce the vulnerability of torsional irregular buildings caused by seismic loads, the torsional amplification factor was introduced by the seismic code. This factor has been applied differently in a variety of seismic codes. In this study, the final static eccentricity, and the lateral and torsional stiffness ratios of buildings designed with different design eccentricities were compared. The increment of the torsional amplification factor resulted in a decrement of the final static eccentricity of the building. However, after reaching the maximum value of this factor, the final static eccentricity of the building increased again. The final static eccentricity of the building designed by multiplying the sum of the inherent and accidental eccentricity by the torsional amplification factor was zero or had a minus value, depending to the position of the vertical element.

• Journal of Korean Medicine Rehabilitation
• /
• v.21 no.4
• /
• pp.23-40
• /
• 2011

Objectives: This study was designed to examine the effects of extracts of Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) on the lipid lowering, anti-oxidation and concentration of proinflammatory cytokines and was investigated on hyperlipidemic rats. Methods: Male rats weighing $182.39{\pm}4.71g$ were fed high fat diet for 8 weeks and 36 rats(above 400 g) were divided into 4 groups. Each of 9 rats was divided a control group and experimental groups. We fed a control group of rats a basal diet and administered normal saline(100 mg/kg, 1 time/1 day) for 4 weeks. And we fed each experimental group of rats basal diet and administered an extract of Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) extracts(100 mg/kg, 200mg/kg, 300 mg/kg, 300 mg/kg, 1 time/1 day) for 4 weeks. At the end of the experiment, the rats were sacrificed to determine their chemical composition. We measured lipid of plasma and liver, concentration of proinflmmatory cytokines, anti-oxidative activity and $TNF-{\alpha}$, Apo-B, Apo-E and leptin gene expression. Results: 1. Concentration of plasma free fatty(FFA) showed no significant difference in all the treatment groups. Concentration of plasma triglyceride(TG) showed a significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. 2. Concentration of plasma total cholesterol showed a significant decrement in the 200 and 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. Concentration of plasma low density lipoprotein(LDL)-cholesterol showed a Significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. Concentration of plasma high density lipoprotein(HDL)-cholesterol showed a significant increment in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group. 3. Concentration of liver total cholesterol showed a tendence to decrease in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups. Concentration of liver TG showed a significant decrement in all Ojeoksangamibang groups than that of control group. 4. Concentration of plasma and liver thiobarbituric acid reactive substance(TBARS) showed a tendence to decrease in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups. 5. The values of glutathione peroxidase(GSH-Px), superoxide dismutase(SOD) and catalase(CAT) activity showed a significant increment in all Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. 6. The values of plasma aspartate aminotransferase(AST) and alanine aminotransferase(ALT) activity showed no significant different in all treatment group. 7. Concentration of plasma $interleukin(IL)-1{beta}$ showed no significant difference in all the treatment groups. Concentration of plasma IL-6 showed a significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group than that of control group. Concentration of plasma tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ a siginifant decrement in the 200 and 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group than that of control group. However the concentration of plasma IL-10 in the 300 mg/kg Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a significant increment than that of control group. 9. In the analysis of reverse transcription-polymerase chain reaction(RT-PCR), gene expression of $TNF-{\alpha}$, Apo-B and Apo-E in the Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a lower expression than that of control group. However the gene expression of leptin showed no difference in the treatment groups. 10. The ratio of $TNF-{\alpha}$, Apo-B, and Apo-E per ${\beta}-actin$ expression in the Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a significant decrement than that of control group. However The ratio of leptin expression per ${\beta}-actin$ expression showed no significant difference among all the treatment groups. Conclusions: According to above results, in lowering lipid effect, anti-oxidation and control of pro-inflammatory cytokines production, Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) gives effect.

• Journal of Korean Neurosurgical Society
• /
• v.64 no.3
• /
• pp.437-446
• /
• 2021

Objective : To investigate the radiographic characteristics of the uppermost instrumented vertebrae (UIV) and UIV+1 compression fractures that are predictive of revision surgery following long-segment spinal fixation. Methods : A total 27 patients who presented newly developed compression fracture at UIV, UIV+1 after long segment spinal fixation (minimum 5 vertebral bodies, lowest instrumented vertebra of L5 or distal) were reviewed retrospectively. Patients were divided into two groups according to following management : revisional surgery (group A, n=13) and conservative care (group B, n=14). Pre- and postoperative images, and images taken shortly before and after the occurrence of fracture were evaluated for radiologic characteristics Results : Despite similar degrees of surgical correction of deformity, the fate of the two groups with proximal junctional compression fractures differed. Immediately after the fracture, the decrement of adjacent disc height in group A (32.3±7.6 mm to 23.7±8.4 mm, Δ=8.5±6.9 mm) was greater than group B (31.0±13.9 mm to 30.1±15.5 mm, Δ=0.9±2.9 mm, p=0.003). Pre-operative magnetic resonance imaging indicated that group A patients have a higher grade of disc degeneration adjacent to fractured vertebrae compared to group B (modified Pfirrmann grade, group A : 6.10±0.99, group B : 4.08±0.90, p=0.004). Binary logistic regression analysis indicated that decrement of disc height was the only associated risk factor for future revision surgery (odds ratio, 1.891; 95% confidence interval, 1.121-3.190; p=0.017). Conclusion : Proximal junctional vertebral compression fractures with greater early-stage decrement of adjacent disc height were associated with increased risk of future neurological deterioration and necessity of revision. The condition of adjacent disc degeneration should be considered regarding severity and revision rate of proximal junctional kyphosis/proximal junction failures.

• Journal of Haehwa Medicine
• /
• v.12 no.2
• /
• pp.177-197
• /
• 2004

1. The values of Cronbach's alpha for the Taeyang, Taeum, Soyang and Soeum questionnaire were 0.7955, 0.7776, 0.8545, and 0.8601 respectively. These results indicate a highly satisfactory level of internal consistency for the questionnaire. 2. If the deletion of an item increases Cronbach's alpha then what that means is that the deletion of that item improves reliability. Therefore, any items that result in substantially greater values of alpha than the overall alpha may need to be deleted from the questionnaire to improve its reliability. 3. Factor analysis was performed on the 81 questionnaires. Based on the scree plot and the number and decrement of eigen values greater than one, three to four factor solution was most significant. 4. The hierarchical cluster analysis was performed on the 81 Sasang constitution questionnaire. These results suggested that two or four clusters identified with homogeneous groups 5. The hierarchical cluster analysis was performed on the 1046 responders. These results suggested that two, three, or four clusters might identified with homogeneous groups. Furthemore, there were statistically significant difference among the each group by ANOVA(P<0.0001).

• Wind and Structures
• /
• v.14 no.3
• /
• pp.253-283
• /
• 2011

This paper presents the field measurement results of wind effects on a super-tall building (CITIC Plaza, 391 m high) located in Guangzhou. The field data such as wind speed, wind direction and acceleration responses were simultaneously and continuously recorded from the tall building by a wind and vibration monitoring system during two typhoons. The typhoon-generated wind characteristics including turbulence intensity, gust factor, peak factor, turbulence integral length scale and power spectral density of fluctuating wind speed were presented and discussed. The dynamic characteristics of the tall building were determined based on the field measurements and compared with those calculated from a 3D finite element model of the building. The measured natural frequencies of the two fundamental sway modes of the building were found to be larger than those calculated. The damping ratios of the building were evaluated by the random decrement technique, which demonstrated amplitude-dependent characteristics. The field measured acceleration responses were compared with wind tunnel test results, which were found to be consistent with the model test data. Finally, the serviceability performance of the super-tall building was assessed based on the field measurement results.