• Title/Summary/Keyword: De-yi

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An unusual de novo duplication 10p/deletion 10q syndrome: The first case in Korea

  • Lee, Bom-Yi;Park, Ju-Yeon;Lee, Yeon-Woo;Oh, Ah-Rum;Lee, Shin-Young;Choi, Eun-Young;Kim, Moon-Young;Ryu, Hyun-Mee;Park, So-Yeon
    • Journal of Genetic Medicine
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    • v.12 no.1
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    • pp.49-56
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    • 2015
  • We herein report an analysis of a female baby with a de novo dup(10p)/del(10q) chromosomal aberration. A prenatal cytogenetic analysis was performed owing to abnormal ultrasound findings including a choroid plexus cyst, prominent cisterna magna, and a slightly medially displaced stomach. The fetal karyotype showed additional material attached to the terminal region of chromosome 10q. Parental karyotypes were both normal. At birth, the baby showed hypotonia, upslanting palpebral fissures, a nodular back mass, respiratory distress, neonatal jaundice and a suspicious polycystic kidney. We ascertained that the karyotype of the baby was 46,XX,der(10)($pter{\rightarrow}q26.3::p11.2{\rightarrow}pter$) by cytogenetic and molecular cytogenetic analyses including high resolution GTG-and RBG-banding, fluorescence in situ hybridization, comparative genomic hybridization, and short tandem repeat marker analyses. While almost all reported cases of 10p duplication originated from one of the parents with a pericentric inversion, our case is extraordinarily rare as the de novo dup(10p)/del(10q) presumably originated from a rearrangement at the premeiotic stage of the parental germ cell or from parental germline mosaicism.

Design of Spatial Relationship for 3D Geometry Model (3차원 기하모델에 대한 공간 관계 연산 설계)

  • Yi Dong-Heon;Hong Sung-Eon;Park Soo-Hong
    • Spatial Information Research
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    • v.13 no.2 s.33
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    • pp.119-128
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    • 2005
  • Most spatial data handled in GIS is two-dimensional. These two-dimensional data is established by selecting 2D aspects form 3D, or by projecting 3D onto 2D space. During this conversion, without user's intention, data are abstracted and omitted. This unwanted data loss causes disadvantages such as restrictingof the range of data application and describing inaccurate real world. Recently, three dimensional data is getting wide interests and demands. One of the examplesis Database Management System which can store and manage three dimensional spatial data. However, this DBMS does not support spatial query which is the essence of the database management system. So, various studies are needed in this field. This research designs spatial relationship that is defined in space database standard using the three-dimension space model. The spatial data model, which is used in this research, is the one defined in OGC for GMS3, and designing tool is DE-9IM based on Point-Set Topology blow as the best method for topological operation.

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The Role of Camera-Based Coincidence Positron Emission Tomography in Nodal Staging of Non-Small Cell Lung Cancer (비소세포폐암의 림프절 병기 결정에서 Coincidence PET의 역할)

  • Lee, Sun-Min;Choi, Young-Hwa;Oh, Yoon-Jung;Cheong, Seong-Cheoll;Park, Kwang-Joo;Hwang, Sung-Chul;Lee, Yi-Hyeong;Park, Chan-H;Hahn, Myung-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.47 no.5
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    • pp.642-649
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    • 1999
  • Background: It is very important to determine an accurate staging of the non-small cell lung cancer(NSCLC) for an assessment of operability and it's prognosis. However, it is difficult to evaluate tumor involvement of mediastinal lymph nodes accurately utilizing noninvasive imaging modalities. PET is one of the sensitive and specific imaging modality. Unfortunately PET is limited use because of prohibitive cost involved with it's operation. Recently hybrid SPECT/PET(single photon emission computed tomography/positron emission tomography) camera based PET imaging was introduced with relatively low cost. We evaluated the usefulness of coincidence detection(CoDe) PET in the detection of metastasis to the mediastinal lymph nodes in patients with NSCLC. Methods: Twenty one patients with NSCLC were evaluated by CT or MRI and they were considered operable. CoDe PET was performed in all 21 patients prior to surgery. Tomographic slices of axial, coronal and sagittal planes were visually analysed. At surgery, mediastinal lymph nodes were removed and histological diagnosis was performed. CoDe PET findings were correlated with histological findings. Results: Twenty of 21 primary tumor masses were detected by the CoDe PET. Thirteen of 21 patients was correctly diagnosed mediastinal lymph node metastasis by the CoDe PET. Pathological N0 was 14 cases and the specificity of N0 of CoDe PET was 64.3%. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of N1 node was 83.3%, 73.3%, 55.6%, 91.7%, and 76.2% respectively. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of N2 node was 60.0%, 87.5%, 60.0%,87.5%, and 90.0% respectively. There were 3 false negative cases but the size of the 3 nodes were less than 1cm. The size of true positive nodes were 1.1cm, 1.0cm, 0.5cm respectively. There were 1 false positive among the 12 lymph nodes which were larger than 1cm. False positive cases consisted of 1 tuberculosis case, 1 pneumoconiosis case and 1 anthracosis case. Conclusion: CoDe PET has relatively high negative predictive value in the enlarged lymph node in staging of mediastinal nodes in patients with NSCLC. Therefore CoDe PET is useful in ruling out metastasis of enlarged N3 nodes. However, further study is needed including more number of patients in the future.

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Jeongjae(正齋) Nam Dae-nyeon's(南大秊) Study and Thought (정재(正齋) 남대년(南大秊)의 학문과 사상)

  • Lim, Ok-kyun
    • The Journal of Korean Philosophical History
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    • no.53
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    • pp.63-100
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    • 2017
  • In this article, I researched Nam Dae-nyeon's(1887~1958) thought of Neo-confucian theories, interpretation of confucian canons, and evaluation of historical figures. First, from the side of Neo-confucian theories, he asserted that Qi(氣) had behaviors and Li(理) had not. About his teacher Jeon Wu's(田愚) theories, he thought that those were in tradition of Confucius(孔子) and Mencius(孟子), but not emphasized presidence of mind. And he criticized the theory of mind was Li(理). Second, from the side of interpretation of Confucian canons, Nam Dae-nyeon's study centered on Four Books(四書). This showed he was in tradition of Neo-confucianism. Through this studies he emphasized the importance of Confucian Ren(仁) and Filial piety(孝), self-consciousness as gentry(士). Third, from the side of evaluation of historical figures, Nam Dae-nyeon evaluated many Chinese and Korean scholars, for example, Qu Yuan(屈原), Lu Zhong-lian(魯仲連), Zhen De-xiu(眞德秀), Lu Long-qi((陸?其), Zhang Lu-xiang (張履祥) of China, and Jeong Mong-ju(鄭夢周), Zho Kwang-jo(趙光祖), Yi Hwang(李滉), Yi Yi(李珥), Jeon Wu(田愚) of Korea. And his criteria for evaluation of historical figures was fidelity and insight.

Penn Korean Treebank: Development and Evaluation

  • Han, Chung-hye;Han, Na-Rae;Ko, Eon-Suk;Martha Palmer;Heejong Yi
    • Proceedings of the Korean Society for Language and Information Conference
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    • 2002.02a
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    • pp.69-78
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    • 2002
  • This paper discusses issues in building a 54-thousand-word Korean Treebank using a phrase structure annotation, along with developing annotation guidelines based on the morpho-syntactic phenomena represented in the corpus. Various methods that were employed for quality control and the evaluation on the Treebank are also presented.

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Perception of Korean Prosody by Native Speakers of English and Native Speakers of Korean (영어 원어민과 한국어 원어민의 한국어운율 인식)

  • Yi, So-Pae
    • MALSORI
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    • no.65
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    • pp.1-11
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    • 2008
  • This study explored the perception of transplanted Korean prosody by NE (Native speakers of English) and NK (Native speakers of Korean) listeners. The Korean utterances of various sentence types produced by NE and NK were employed to transplant the original Korean prosody contours to the Korean utterances read by NE. Then, other NE and NK were instructed to rate the transplanted prosodic components. Results showed that the interactions between the two rater groups with the three factors (e.g., transplantation types & rater groups, sentence types & rater groups, sentence length & rater groups) turned out to be meaningful. Both rater groups preferred the combined effect of transplanted prosodic components (e.g. DP, DPI) to that of individual transplantation (e.g. I, D, P). Compared to NK, NE were more sensitive to duration change than pitch change whereas NK showed equal preference to the both. In sentence types such as De, Ex, Im, and Ta, NE perceived higher similarity than NK.

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Specification of Communication Services for Multimedia Cooperative Applications Based on the Reference Model of ODP

  • Yi, Jong-Hwa;Pastor, Encarna
    • ETRI Journal
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    • v.20 no.2
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    • pp.149-170
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    • 1998
  • Between a wide range of distributed applications, this work is particularly focused on those applications which allow a group of persons, who are geographically distributed, to interact and cooperate exchanging different kind of information in order to realize group activities in a common work environment. In this paper we realized a study of this kind of applications to identify general and functional characteristics which will then enable us to determine their communication requirements. Also, we analyzed the existent support architectures to examine whether they support multimedia cooperative applications. Based on the results of analysis, we proposed a set of communication functions needed additionally to support these applications, using the ODP(Open Distributed Processing) modelling concepts, rules and view points as our global design methodology.

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복온공주(福溫公主) 복식유품(服飾遺品)에 나타난 문양(紋樣)에 관한 소고(小考)

  • Lee, Sang-Eun
    • Journal of the Korean Society of Costume
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    • v.15
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    • pp.63-76
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    • 1990
  • The purpose of this paper is to de31 with the sorts, significances and characteristics of the devices embroiderered on the ritual dreses(hwarot), skirts and embroidered-cushions among the relics of Princess Bok-On(A.D. $1818{\sim}1834$), the second daughter of King Soon-Jo(A.D. $1790{\sim}1834$) in the Yi Dynasty. Her ritual dresses(hwarot)adopt the devices of Buddhism style, Taoism one, Chinese one and Korean one together in mixture, and have no letter-devices in embroidering treasure-devices. Her skirts have the ornament signifying the Orientalism, and express the spiritual world symbolically and artistically. Her embroidered-cushions make harmonization of Confucianism and Buddhism on the splendid base-cloth, and create a unique art style of Korea.

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On the evolution of observable properties from equal-mass disk merger simulations

  • Ji, Inchan;Peirani, Sebastien;Yi, Sukyoung
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.1
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    • pp.32.1-32.1
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    • 2013
  • We use numerical simulations to investigate the evolution of both the star formation rate (SFR) and the observable properties of equal-mass disk merger remnants for 18 different orbital configurations. In our analysis, the photometric properties of the remnants have been constructed by considering dust reddening effect in order to facilitate the comparison with observational data of large surveys such as the Sloan Digital Sky Survey (SDSS). First, we found that the detailed evolutions of merging galaxies are different between the merging characteristics such as merging time scale, SFR history, and burst efficiency. Around $70{\pm}5$ percent of gas turns into stars until the merger-induced starburst ends regardless of merger types. Our study also suggests that merger features involve a small fraction of stars. Merger features last roughly 3 times the final coalescence time of galaxy mergers. For a shallower surface brightness limit, the features seem to survive in a shorter time, which is the reason why detecting merger features by using shallow surveys were difficult in the past.

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Fuzzy AHP Approach to TQM Strategy Evaluation

  • Tseng, Ming-Lang;Lin, Yuan-Hsu;Chiu, Anthony SF;Chen, Chia Yi
    • Industrial Engineering and Management Systems
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    • v.7 no.1
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    • pp.34-43
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    • 2008
  • In recent years, many electronics producing firms have looked upon total quality management (TQM) strategy as a means by which they could maintain competitive advantage. This empirical research evaluates TQM strategic factors in order to determine the critical success factors in environmental uncertainty. Fuzzy analytic hierarchy process (FAHP) is the proposed research methodology to discuss and tackle the different decision criteria like effective leadership, people management, customer focus, strategic plan and process management, being involved in identifying the TQM strategic critical success factors with uncertainty. The result shows that effective leadership is the most critical success factor in TQM strategy.