• Journal of Intelligence and Information Systems
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• v.29 no.4
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• pp.1-13
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• 2023

The widespread adoption of smartphones and advancements in internet technology have notably shifted content consumption habits toward video. This research aims to dissect the nature of videos posted on YouTube, the global video-sharing platform, to understand the characteristics of both produced and preferred content. For this study, dance was chosen as a specific subject from a variety of video categories. Data on YouTube videos associated with the term "dance" was compiled over three years, from 2019 to 2021. The investigation revealed a clear distinction between the types of dance videos frequently uploaded to YouTube and those that receive a high number of views. The empirical analysis of this study indicates a viewer preference for vlogs that provide insights into the daily lives of dance students, as well as for purpose-driven videos, such as those highlighting dance exam preparations or school dance events. Notably, the vlogs that attract the most attention are typically created by dance students at the college or secondary school level, rather than by professionals. Although the study was focused on dance, its methodologies can be applied to different subjects. These insights are expected to contribute to the development of a recommendation system that aids content creators in effectively targeting their productions.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.29 no.2
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• pp.101-115
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• 2024

The ocean heatwave is emerging as a major issue due to global warming, posing a direct threat to marine ecosystems and humanity through decreased food resources and reduced carbon absorption capacity of the oceans. Consequently, the prediction of ocean heatwaves in the vicinity of the Korean Peninsula is becoming increasingly important for marine environmental monitoring and management. In this study, an LSTM model was developed to improve the underestimated prediction of ocean heatwaves caused by the coarse vertical grid system of the Korean Peninsula Ocean Prediction System. Based on the results of ocean heatwave predictions for the Korean Peninsula conducted in 2023, as well as those generated by the LSTM model, the performance of heatwave predictions in the East Sea, Yellow Sea, and South Sea areas surrounding the Korean Peninsula was evaluated. The LSTM model developed in this study significantly improved the prediction performance of sea surface temperatures during periods of temperature increase in all three regions. However, its effectiveness in improving prediction performance during periods of temperature decrease or before temperature rise initiation was limited. This demonstrates the potential of the LSTM model to address the underestimated prediction of ocean heatwaves caused by the coarse vertical grid system during periods of enhanced stratification. It is anticipated that the utility of data-driven artificial intelligence models will expand in the future to improve the prediction performance of dynamical models or even replace them.

• BMB Reports
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• v.57 no.6
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• pp.281-286
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• 2024

Adult hippocampal neurogenesis plays a pivotal role in maintaining cognitive brain function. However, this process diminishes with age, particularly in patients with neurodegenerative disorders. While small, non-coding microRNAs (miRNAs) are crucial for hippocampal neural stem (HCN) cell maintenance, their involvement in neurodegenerative disorders remains unclear. This study aimed to elucidate the mechanisms through which miRNAs regulate HCN cell death and their potential involvement in neurodegenerative disorders. We performed a comprehensive microarray-based analysis to investigate changes in miRNA expression in insulin-deprived HCN cells as an in vitro model for cognitive impairment. miR-150-3p, miR-323-5p, and miR-370-3p, which increased significantly over time following insulin withdrawal, induced pronounced mitochondrial fission and dysfunction, ultimately leading to HCN cell death. These miRNAs collectively targeted the mitochondrial fusion protein OPA1, with miR-150-3p also targeting MFN2. Data-driven analyses of the hippocampi and brains of human subjects revealed significant reductions in OPA1 and MFN2 in patients with Alzheimer's disease (AD). Our results indicate that miR-150-3p, miR-323-5p, and miR-370-3p contribute to deficits in hippocampal neurogenesis by modulating mitochondrial dynamics. Our findings provide novel insight into the intricate connections between miRNA and mitochondrial dynamics, shedding light on their potential involvement in conditions characterized by deficits in hippocampal neurogenesis, such as AD.

• Korean Journal of Radiology
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• v.25 no.6
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• pp.565-574
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• 2024

Objective: To evaluate the safety and clinical outcomes of the Passeo-18 Lux drug-coated balloon (DCB) in endovascular revascularization procedures under real-world conditions in a Korean population with atherosclerotic disease of the infrainguinal arteries, including below-the-knee (BTK) arteries. Materials and Methods: Eight institutions in the Republic of Korea participated in this prospective, multicenter, single-arm, post-market surveillance study. Two hundred patients with Rutherford class 2-5 peripheral arterial disease and infrainguinal lesions suitable for endovascular treatment were competitively enrolled. Data were collected at baseline, the time of intervention, discharge, and 1-, 6-, 12-, and 24-month follow-up visits. The primary safety endpoint was freedom from major adverse events (MAE) within 6 months (except when limiting the time frame for procedure- or device-related mortality to within 30 days), and the primary effectiveness endpoint was freedom from clinically driven target lesion revascularization (CD-TLR) within 12 months after the procedure. Results: A total of 197 patients with 332 target lesions were analyzed. Two-thirds of the patients had diabetes mellitus, and 41.6% had chronic limb-threatening ischemia. The median target lesion length was 100 mm (interquartile range: 56-133 mm). Of the target lesions, 35.2% were occlusions, and 14.8% were located in the BTK arteries. Rate of freedom from MAE was 97.9% at 6 months, and the rate of freedom from CD-TLR was 95.0% and 92.2% at 12 and 24 months, respectively. Subgroup analysis of 43 patients and 49 target lesions involving the BTK arteries showed rate of freedom from MAE of 92.8% at 6 months and rates of freedom from CD-TLR of 88.8% and 84.4% at 12 and 24 months, respectively. Conclusion: The results of the present study, including the BTK subgroup analysis, showed outcomes comparable to those of other DCB studies, confirming the safety and effectiveness of Passeo-18 Lux DCB in the Korean population.

• Korean Journal of Ecology and Environment
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• v.57 no.2
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• pp.83-91
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• 2024

This study utilizes association rule learning and clustering analysis to explore the co-occurrence and relationships within ecosystems, focusing on the endangered brackish-water snail Clithon retropictum, classified as Class II endangered wildlife in Korea. The goal is to analyze co-occurrence patterns between brackish-water snails and other species to better understand their roles within the ecosystem. By examining co-occurrence patterns and relationships among species in large datasets, association rule learning aids in identifying significant relationships. Meanwhile, K-means and hierarchical clustering analyses are employed to assess ecological similarities and differences among species, facilitating their classification based on ecological characteristics. The findings reveal a significant level of relationship and co-occurrence between brackish-water snails and other species. This research underscores the importance of understanding these relationships for the conservation of endangered species like C. retropictum and for developing effective ecosystem management strategies. By emphasizing the role of a data-driven approach, this study contributes to advancing our knowledge on biodiversity conservation and ecosystem health, proposing new directions for future research in ecosystem management and conservation strategies.

• Journal of the Korean Society of Marine Environment & Safety
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• v.30 no.4
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• pp.365-372
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• 2024

The South Korean marine industry is emerging as a significant market, driven by the growing popularity of various water leisure activities, including sailing. This trend suggests a rising demand for sailing yachts. Consequently, since 2022, the design and development of a 28ft sailing yacht have been ongoing, supported by the government and the Ministry of Oceans and Fisheries, to promote yachting culture in South Korea. The Velocity Prediction Program (VPP) analysis was conducted using WinDesign during the preliminary design stage to evaluate performance and determine design parameters. The hydrodynamic model used for this vessel is based on regression methods developed from years of experience in naval architecture and yacht research at the Wolfson Unit, providing reliable estimates for most modern yachts. However, owing to the lack of specific hydrodynamic data from towing tank tests or CFD numerical analysis, verification of the hydrodynamic model has faced some challenges. Additionally, an incomplete weight estimate resulted in variable VCG values, potentially affecting stability and overall performance. The optimal boat speed for this vessel was determined at true wind speeds (TWS) of 4, 8, 12, 16, and 20 knots, using both the jib (up to 120° TWA) and the spinnaker (from 80° TWA). The optimized speed of the yacht was found to be comparable to that of international similar-class yachts.

• Korean Circulation Journal
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• v.54 no.8
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• pp.454-465
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• 2024

Background and Objectives: The popliteal artery is generally regarded as a "no-stent zone." Limited data are available on the outcomes of drug-coated balloons (DCBs) for popliteal artery disease. This study aimed to evaluate the 12-month clinical outcomes among patients who received DCB treatment for atherosclerotic popliteal artery disease. Methods: This prospective, multicenter registry study enrolled 100 patients from 7 Korean endovascular centers who underwent endovascular therapy using IN.PACT DCB (Medtronic) for symptomatic atherosclerotic popliteal artery disease. The primary endpoint was 12-month clinical primary patency and the secondary endpoint was clinically driven target lesion revascularization (TLR)-free rate. Results: The mean age of the study cohort was 65.7±10.8 years, and 77% of enrolled patients were men. The mean lesion length was 93.7±53.7 mm, and total occlusions were present in 45% of patients. Technical success was achieved in all patients. Combined atherectomy was performed in 17% and provisional stenting was required in 11%. Out of the enrolled patients, 91 patients completed the 12-month follow-up. Clinical primary patency and TLR-free survival rates at 12 months were 76.0% and 87.2%, respectively. A multivariate Cox regression analysis identified female and longer lesion length as the significant independent predictors of loss of patency. Conclusions: DCB treatment yielded favorable 12-month clinical primary patency and TLR-free survival outcomes in patients with popliteal artery disease.

• International Journal of Heart Failure
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• v.6 no.2
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• pp.56-69
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• 2024

Background and Objectives: The number of people with heart failure (HF) is increasing worldwide, and the social burden is increasing as HF has high mortality and morbidity. We aimed to provide updated trends on the epidemiology of HF in Korea to shape future social measures against HF. Methods: We used the National Health Information Database of the National Health Insurance Service to determine the prevalence, incidence, hospitalization rate, mortality rate, comorbidities, in-hospital mortality, and healthcare cost of patients with HF from 2002 to 2020 in Korea. Results: The prevalence of HF in the total Korean population rose from 0.77% in 2002 to 2.58% (1,326,886 people) in 2020. Although the age-standardized incidence of HF decreased over the past 18 years, the age-standardized prevalence increased. In 2020, the hospitalization rate for any cause in patients with HF was 1,166 per 100,000 persons, with a steady increase from 2002. In 2002, the HF mortality was 3.0 per 100,000 persons, which rose to 15.6 per 100,000 persons in 2020. While hospitalization rates and in-hospital mortality for patients with HF increased, the mortality rate for patients with HF did not (5.8% in 2020), and the one-year survival rate from the first diagnosis of HF improved. The total healthcare costs for patients with HF were approximately $2.4 billion in 2020, a 16-fold increase over the $0.15 billion in 2002. Conclusions: The study's results underscore the growing socioeconomic burden of HF in Korea, driven by an aging population and increasing HF prevalence.

• Journal of Internet Computing and Services
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• v.25 no.4
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• pp.23-37
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• 2024

Digital twin is an M&S (Modeling and Simulation) technology designed to solve or optimize problems in the real world by replicating physical objects in the real world as virtual objects in the digital world and predicting phenomena that may occur in the future through simulation. Digital twins have been elaborately designed and utilized based on data collected to achieve specific purposes in large-scale environments such as cities and industrial facilities. In order to apply this digital twin technology to real life and expand it into user-customized service technology, practical but sensitive issues such as personal information protection and personalization of simulations must be resolved. To solve this problem, this paper proposes a federated learning-based accelerated client training method (FACTS) for personalized digital twins. The basic approach is to use a cluster-driven federated learning training procedure to protect personal information while simultaneously selecting a training model similar to the user and training it adaptively. As a result of experiments under various statistically heterogeneous conditions, FACTS was found to be superior to the existing FL method in terms of training speed and resource efficiency.

• Korean Circulation Journal
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• v.54 no.9
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• pp.565-576
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• 2024

Background and Objectives: The K-ELUVIA study aimed to investigate the clinical effectiveness and safety of Eluvia^TM, a polymer-coated, paclitaxel-eluting stent, for femoropopliteal artery disease using data from a prospective Korean multicenter registry. Methods: A total of 105 patients with femoropopliteal artery disease who received endovascular treatment (EVT) with Eluvia^TM stents at 7 Korean sites were enrolled in a prospective cohort and followed for 2 years. The primary endpoint was the 2-year clinical patency. The secondary endpoint was 2-year freedom from clinically driven target lesion revascularization (TLR). Results: Mean patient age was 68.2±10.4 years, and most patients (82.7%) were male. Mean lesion length was 168.3±117.6 mm. Chronic total occlusion was found in 57.7% of patients. Trans-Atlantic Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II) type C or D lesions were present in 46.1% of patients. Procedural success was achieved in 99.0% of patients. The clinical patency rate was 84.4% at 1 year after EVT and 76.3% at 2 years post-EVT. The freedom from TLR rate was 89.1% at 1 year after EVT and 79.1% at 2 years post-EVT. Chronic total occlusion (hazard ratio [HR], 3.53; 95% confidence interval [CI], 1.08-11.67; p=0.039) and smaller mean stent diameter (HR, 0.40; 95% CI, 0.16-0.98; p=0.044) were identified as independent predictors of loss of clinical patency at 2 years. Conclusions: The K-ELUVIA study demonstrated favorable 2-year clinical effectiveness and safety outcomes of Eluvia stent for femoropopliteal artery lesions in real-world practice.