• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.2
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• pp.562-570
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• 2019

The purpose of this study was to identify the factors influencing the quality of sleep in breast cancer patients receiving chemotherapy in the outpatient settings. The data were collected from 203 patients with breast cancer receiving chemotherapy in the outpatient settings at one tertiary hospital in B City. Stress, fatigue and depression were negatively correlated with quality of sleep (r=-.369, p=.001; r=-.565, p=.001; r=-.526, p=.001, respectively). Fatigue(${\beta}=-.387$, p<.001) was one of the biggest impact factors on quality of sleep which explained 31.6% of the variance of the sleep quality, followed by the experience of sleep disturbances prior to the diagnosis of breast cancer(${\beta}=-.178$, p<.002) and depression(${\beta}=-.231$, p<.004). In total, all of the antecedent variables explained significantly 37.4% of the variance of the sleep quality. Thus, in order to improve the quality of sleep, integrative nursing interventions need to be developed to reduce fatigue and depression among them, including an proactive system to screen out the patients with the experience of sleep disturbances prior to the diagnosis with breast cancer and to provide adequate pharmacological and/or non-pharmacological sleep interventions prior to the chemotherapy.

• The Korean Journal of Rehabilitation Nursing
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• v.4 no.2
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• pp.219-231
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• 2001

The purpose of this study was to investigate the relationship among percieved social support, hope and quality of life of the cancer patients and to gain the baseline data for development of nursing intervention program for promoting quality of life in cancer patients. The design of this study was a cross sectional correlational survey. The subjects were 220 out and in-cancer patients in 5 general hospitals in Pusan. The data were collected from July 2 to August 1, 2001. The instruments were the Percieved social support scale(16 items, 5 point scale) had developed by Tae(1986), Hope scale(12 items, 4point scale) developed by Nowotny(1989) and Quality of life scale(31 items, 10 point scale) developed by Tae et al.(2000). The data was analyzed by the SPSS/PC+ program using frequency & percentage, item mean & standard deviation, t-test, ANOVA & Scheffe test, Pearson's correlation coefficient. The results of this study was as follows: 1) The item mean score of quality of life was $6.05{\pm}1.16$ (range 0-10). The highest score of subarea of the quality of life was the spiritual wellbeing area ($7.09{\pm}1.63$) and the lowest score was social wellbeing area ($5.53{\pm}1.65$). The mean score of perceived social support was $52.65{\pm}10.32$ (최저 1, 최고 80). The mean score of family support was $32.71{\pm}6.66$ (range 1-40) and the mean score of medical team support was $19.93{\pm}5.95$ (range 1-40). The mean score of Hope was $37.02{\pm}5.64$ (range 1-48). 2) There were statistically significant difference in the score of quality of life according to the life effect of religion(F=3.97, p=0.00), treatment method(F=2.94, p=0.01), area of diagnosis(F= 3.48, p=0.01), stage of disease (F=13.74, p=0.00). 3) There was significant correlation between perceived social support(r=0.44, p=0.000 ; family support ; r=0.334, p=0.000, medical support; r=0.395, p=0.000), hope(r=0.563, p=0.000) and quality of life. In conclusion, there was a significant relationship among perceived social support, hope and quality of life. Therefore perceived social support, hope intervention programs should be developed to improve the quality of life in cancer patients.

• The Journal of Korean Society for School & Community Health Education
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• v.12 no.3
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• pp.1-15
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• 2011

Objectives: We describe the development of a smoking and drinking prevention program for adolescents, using intervention mapping. Methods: The study sample consisted of 1,000 high school second-grade students from 6 high schools in Seoul. The PRECEDE model was applied for the needs assessment. We carried out a social diagnosis by assessing the factors such as the quality of life, happiness level, and satisfaction with school life; an epidemiological diagnosis on the perceived health status, stress levels, and priority of health issues; a behavioral diagnosis on the smoking and drinking rate and the intention to smoke and drink; and an educational diagnosis on knowledge, beliefs, attitudes, self-efficacy, outcome expectations, social norms and life skills. Results: The development process included a needs assessment, identifying factors that influence smoking and drinking among adolescents. Intention, knowledge, perceived norms, perceived benefit, perceived cost, perceived susceptibility, self-efficacy, and life skills were identified as determinants. Three performance objectives were formulated to describe what an individual needs to do in order to avoid smoking and drinking. Subsequently, we constructed an intervention matrix by crossing the performance objectives with the selected determinants. Each cell describes the learning objectives of the smoking and drinking prevention program. The program used methods from the transtheoretical model, such as consciousness raising, outcome expectations, self-reevaluation, self-liberation, counterconditioning, environmental reevaluation, and stimulus control. The program deals with the effects of smoking and drinking, self-improvement, decision making, understanding advertisements, communication skills, social relationships, and assertiveness. Conclusions: By using the process of intervention mapping, the program developer was able to ensure a systematical incorporation of empirical and new data and theories to guide the intervention design. Programs targeting other health-related behavior and other methods or strategies can also be developed using this intervention mapping process.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.1
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• pp.89-99
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• 2020

Although microscopic analysis of tissue slides has been the basis for disease diagnosis for decades, intra- and inter-observer variabilities remain issues to be resolved. The recent introduction of digital scanners has allowed for using deep learning in the analysis of tissue images because many whole slide images (WSIs) are accessible to researchers. In the present study, we investigated the possibility of a deep learning-based, fully automated, computer-aided diagnosis system with WSIs from a stomach adenocarcinoma dataset. Three different convolutional neural network architectures were tested to determine the better architecture for tissue classifier. Each network was trained to classify small tissue patches into normal or tumor. Based on the patch-level classification, tumor probability heatmaps can be overlaid on tissue images. We observed three different tissue patterns, including clear normal, clear tumor and ambiguous cases. We suggest that longer inspection time can be assigned to ambiguous cases compared to clear normal cases, increasing the accuracy and efficiency of histopathologic diagnosis by pre-evaluating the status of the WSIs. When the classifier was tested with completely different WSI dataset, the performance was not optimal because of the different tissue preparation quality. By including a small amount of data from the new dataset for training, the performance for the new dataset was much enhanced. These results indicated that WSI dataset should include tissues prepared from many different preparation conditions to construct a generalized tissue classifier. Thus, multi-national/multi-center dataset should be built for the application of deep learning in the real world medical practice.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.10
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• pp.4723-4727
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• 2016

Background: There are substantial differences in the mortality rates of stomach cancer among the 47 prefectures in Japan, and Aomori prefecture is one of the most severely impacted. The aims of this study were to determine the incidence and mortality rates of stomach cancer in Aomori prefecture in comparison with Japan as a whole and cast light on reasons underlying variation. Methods: Data on stomach cancer cases were extracted from the Aomori Cancer Registry Database. Incidence rates for specific stages at the time of diagnosis were cited from Monitoring of Cancer Incidence in Japan, and mortality rates for stomach cancer in Aomori prefecture and the whole of Japan were obtained from Vital Statistics. Age-standardised incidence and mortality rates were calculated using the direct method. Results: The age-standardised incidence rate of stomach cancer in Aomori prefecture was higher than in the whole of Japan for males but lower for females. However, the age-standardised mortality rates were higher in Aomori prefecture in both sexes. The proportion of localised cancers was lower in Aomori prefecture than in the whole of Japan for most age groups. Conclusions: The lower rate for localised cancer suggests that higher age-standardised mortality rates are due to delays in diagnosis, despite an attendance rate for stomach cancer screening was higher in Aomori prefecture than in the whole of Japan. One plausible explanation for the failure of successful early detection might be poor quality control during screening implementation that impedes early detection.

• Korean Journal of Clinical Pharmacy
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• v.19 no.2
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• pp.81-88
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• 2009

Objectives: With more and more health economic evaluations being performed in many countries, the question of whether the results from the foreign studies can be transferred to other country is becoming important. The objective of this study was to conduct a case study using three transferability diagnosis tools for economic evaluation on rheumatoid arthritis. Methods: Three diagnosis tools were used to assess transferability: Welte's tool, Boulenger's and Urdahl's. Five researchers who have experience on economic evaluation made consensus on the evaluation through the semi-delphi method. Results: With Welte's tool, absolute and relative prices in healthcare, practice variation, health-status preference, productivity and work-loss time were evaluated as biased. The transferability information score by Boulenger's was 85.9%, which means qood quality reporting. In case of Urdahl's, research questions were well defined and reporting was transparent and explicitly stated. However, both the relevance of data inputs to Korea and robustness of model were relatively low. In conclusion the UK study on rheumatoid arthritis could be partially transferable to Korea, and will need modeling-based adjustments.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.5869-5873
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• 2015

Background: Breast and cervical cancers are among the most frequent and most fatal cancers in women. Life span of patients may be increased and quality of life improved through early diagnosis and treatment. This investigation was performed in order to determine knowledge and practices of female health personnel working at a university hospital regarding breast and cervical cancers. Materials and Methods: This descriptive investigation was performed in Erciyes University Hospitals in 2014. A total of 524 female health personnel were included in the study. Data were collected through a questionnaire of 36 questions prepared by the researchers. The Chi square test and logistic regression were used for statistical analyses. Results: The mean age of the study group was $32.8{\pm}6.9$ years, 18.3% being doctors and 81.7% nurses. Of the study group, 60.5% stated that they performed self breast-examination, 4.4% underwent HPV testing, 26.3% thought about taking an HPV test, 34.7% of those who are 40 years and over had mammography regularly and 19.5% of those who were married had a Pap smear conducted regularly. Most important causes of not performing the methods for early diagnosis of breast and cervical cancers are "forget and neglect". Conclusions: It was concluded that female doctors and nurses do not pay sufficient attention to screening programs for breast and cervical cancers. The importance of early diagnosis and treatment should be emphasized during the undergraduate education and in-service training programs. Health condition of personnel and their utilization of preventive health care should be followed by occupational physicians.

• Journal of the Korean Society for Precision Engineering
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• v.13 no.5
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• pp.84-94
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• 1996

In order to prevent shell sticking by providing sufficient lubrication between the strand and the mold, the mold oscillation has been used. Now it is well known that the shape of the oscillation curve has a decisive effect on the surface quality of the cast product. Besides, oscillation parameters such as stroke and frequency are also very important. In order to guarantee that parameters which have been found to be optimal for a certain grade of steel do not change with time, periodical checks of the physical condition of the whole equipment are necessary. The portable mold oscillation analyzer with integrated computer, developed by POSCO, records the movement of the mold in every spatial direction. The system uses the gap sensors to measure the mold movement (displacement ) in the two horizontal directions according to the mold narrow and broad faces and the vertical strokes in the four corners of mold. The gap sensor is a non-contacting minute displacement measuring device using the principle of high frequency eddy current loss. The mold oscillation diagnosis system integrates the gap sensors, their converters and the industrial portable computer with plug-in data acquisition boards. The all programs, such as the fast Fourier transformation module (amplitude and phase spectrums) and harmonic analysis module, was coded by LabVIEW$^{TM}$ software as the graphical language. In an own 'expert module' which is included in the diagnosis program, one can obtain much information about the mold oscillation equipment.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.3
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• pp.40-45
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• 2018

Intelligent monitoring and diagnosis of production processes based on multivariate statistical methods has been one of important tasks for safety and quality issues. This is due to the fact that faults and unexpected events may have serious impacts on the operation of processes. This study proposes a diagnostic scheme based on effective representation of process measurement data and is evaluated using simulation process data. The effects of utilizing a preprocessing step and nonlinear statistical methods are also tested using fifteen faults of the simulation process. Results show that the proposed scheme produced more reliable results and outperformed other tested schemes with none of the filtering step and nonlinear methods. The proposed scheme is expected to be robust to process noises and easy to develop due to the lack of required rigorous mathematical process models or expert knowledge.

• Journal of Korean Society for Quality Management
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• v.45 no.1
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• pp.25-38
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• 2017

Purpose: Hot strip rolling mill consists of a lot of mechanical and electrical units. In condition monitoring and diagnosis phase, various units could be failed with unknown reasons. In this study, we propose an effective method to detect early the units with abnormal status to minimize system downtime. Methods: The early warning problem with various units is defined. K-means and PAM algorithm with Euclidean and Manhattan distances were performed to detect the abnormal status. In addition, an performance of the proposed algorithm is investigated by field data analysis. Results: PAM with Manhattan distance(PAM_ManD) showed better results than K-means algorithm with Euclidean distance(K-means_ED). In addition, we could know from multivariate field data analysis that the system reliability of hot strip rolling mill can be increased by detecting early abnormal status. Conclusion: In this paper, clustering-based monitoring and fault detection algorithm using Manhattan distance is proposed. Experiments are performed to study the benefit of the PAM with Manhattan distance against the K-means with Euclidean distance.